Rattus norvegicus

0 known processes

Spic

Spi-C transcription factor (Spi-1/PU.1 related)

Spic biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.102
oxoacid metabolic process GO:0043436 290 0.101
organic acid metabolic process GO:0006082 292 0.084
reproductive process GO:0022414 372 0.076
intracellular signal transduction GO:0035556 314 0.074
cellular amino acid metabolic process GO:0006520 107 0.060
response to extracellular stimulus GO:0009991 380 0.058
cell activation GO:0001775 97 0.053
multicellular organism reproduction GO:0032504 233 0.052
leukocyte activation GO:0045321 76 0.049
localization of cell GO:0051674 202 0.049
macromolecule localization GO:0033036 252 0.045
cellular component movement GO:0006928 248 0.043
negative regulation of metabolic process GO:0009892 331 0.043
response to nutrient levels GO:0031667 370 0.042
regulation of cell differentiation GO:0045595 320 0.042
single organism reproductive process GO:0044702 297 0.041
chemical homeostasis GO:0048878 292 0.041
immune system process GO:0002376 204 0.041
defense response GO:0006952 194 0.040
multicellular organismal reproductive process GO:0048609 233 0.039
response to nutrient GO:0007584 248 0.039
multi organism reproductive process GO:0044703 262 0.039
regulation of programmed cell death GO:0043067 341 0.039
organic substance catabolic process GO:1901575 316 0.038
regulation of signal transduction GO:0009966 318 0.038
regulation of secretion GO:0051046 224 0.037
homeostatic process GO:0042592 331 0.037
amine metabolic process GO:0009308 38 0.037
positive regulation of transport GO:0051050 245 0.036
inflammatory response GO:0006954 150 0.036
cell motility GO:0048870 202 0.035
protein phosphorylation GO:0006468 345 0.035
catabolic process GO:0009056 351 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
cellular ketone metabolic process GO:0042180 51 0.032
secretion by cell GO:0032940 248 0.032
response to wounding GO:0009611 254 0.032
regulation of phosphate metabolic process GO:0019220 349 0.032
single organism biosynthetic process GO:0044711 342 0.032
response to cytokine GO:0034097 215 0.032
regulation of protein metabolic process GO:0051246 289 0.032
cellular amine metabolic process GO:0044106 38 0.031
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.031
cell migration GO:0016477 197 0.031
lipid metabolic process GO:0006629 283 0.031
biological adhesion GO:0022610 110 0.030
proteolysis GO:0006508 175 0.030
small molecule biosynthetic process GO:0044283 124 0.030
programmed cell death GO:0012501 392 0.030
reproduction GO:0000003 245 0.030
positive regulation of biosynthetic process GO:0009891 319 0.029
transcription dna templated GO:0006351 377 0.029
sexual reproduction GO:0019953 148 0.029
cellular homeostasis GO:0019725 252 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.028
regulation of molecular function GO:0065009 398 0.028
response to carbohydrate GO:0009743 183 0.028
aging GO:0007568 241 0.028
positive regulation of molecular function GO:0044093 230 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
positive regulation of catalytic activity GO:0043085 184 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
response to peptide GO:1901652 292 0.026
regeneration GO:0031099 163 0.026
regulation of protein phosphorylation GO:0001932 183 0.026
oxidation reduction process GO:0055114 304 0.026
response to lipopolysaccharide GO:0032496 191 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
cellular response to oxygen containing compound GO:1901701 386 0.025
negative regulation of innate immune response GO:0045824 4 0.025
positive regulation of cellular protein metabolic process GO:0032270 167 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
positive regulation of lipid kinase activity GO:0090218 2 0.025
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.025
response to metal ion GO:0010038 253 0.025
locomotion GO:0040011 237 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
cellular ion homeostasis GO:0006873 184 0.024
cellular response to cytokine stimulus GO:0071345 127 0.024
organophosphate metabolic process GO:0019637 370 0.024
cellular catabolic process GO:0044248 295 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
regulation of rna metabolic process GO:0051252 391 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
negative regulation of cell death GO:0060548 229 0.024
regulation of intracellular signal transduction GO:1902531 218 0.023
response to glucose GO:0009749 136 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.023
positive regulation of cell death GO:0010942 184 0.023
response to peptide hormone GO:0043434 278 0.023
regulation of phosphorylation GO:0042325 248 0.023
neuron differentiation GO:0030182 368 0.023
cell type specific apoptotic process GO:0097285 134 0.023
regulation of cell proliferation GO:0042127 359 0.023
regulation of catalytic activity GO:0050790 304 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.022
regulation of response to stress GO:0080134 126 0.022
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
protein localization GO:0008104 191 0.022
apoptotic process GO:0006915 381 0.022
regulation of hydrolase activity GO:0051336 143 0.021
endocytosis GO:0006897 84 0.021
cellular lipid metabolic process GO:0044255 208 0.021
regulation of lipid metabolic process GO:0019216 68 0.021
regulation of immune response to tumor cell GO:0002837 3 0.021
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.021
regulation of neurogenesis GO:0050767 247 0.021
cellular response to lipid GO:0071396 201 0.021
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
response to acid chemical GO:0001101 222 0.021
cellular metal ion homeostasis GO:0006875 172 0.021
carbohydrate metabolic process GO:0005975 130 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
negative regulation of response to stimulus GO:0048585 155 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
single organism catabolic process GO:0044712 283 0.020
regulation of protein modification process GO:0031399 194 0.020
anion transport GO:0006820 178 0.020
cation transport GO:0006812 382 0.020
positive regulation of programmed cell death GO:0043068 157 0.020
rna biosynthetic process GO:0032774 380 0.020
calcium ion homeostasis GO:0055074 162 0.020
establishment of protein localization GO:0045184 141 0.020
positive regulation of signaling GO:0023056 270 0.020
positive regulation of apoptotic process GO:0043065 154 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
positive regulation of cell communication GO:0010647 271 0.020
response to inorganic substance GO:0010035 377 0.020
single organism carbohydrate metabolic process GO:0044723 118 0.019
response to purine containing compound GO:0014074 126 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
secretion GO:0046903 307 0.019
regulation of rna biosynthetic process GO:2001141 381 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
response to external biotic stimulus GO:0043207 221 0.019
negative regulation of immune response to tumor cell GO:0002838 2 0.019
cell adhesion GO:0007155 110 0.018
nucleic acid templated transcription GO:0097659 379 0.018
ion transmembrane transport GO:0034220 365 0.018
response to oxygen levels GO:0070482 265 0.018
ion homeostasis GO:0050801 212 0.018
regulation of transferase activity GO:0051338 123 0.018
regulation of angiogenesis GO:0045765 39 0.018
central nervous system development GO:0007417 311 0.018
positive regulation of angiogenesis GO:0045766 28 0.018
response to bacterium GO:0009617 200 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
angiogenesis GO:0001525 53 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
response to biotic stimulus GO:0009607 226 0.018
negative regulation of response to tumor cell GO:0002835 2 0.018
cellular cation homeostasis GO:0030003 180 0.018
regulation of secretion by cell GO:1903530 208 0.018
regulation of kinase activity GO:0043549 117 0.017
neuron projection development GO:0031175 273 0.017
positive regulation of signal transduction GO:0009967 175 0.017
b cell mediated immunity GO:0019724 4 0.017
immunoglobulin mediated immune response GO:0016064 4 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
leukocyte cell cell adhesion GO:0007159 4 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
response to ketone GO:1901654 182 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
protein complex assembly GO:0006461 263 0.017
cation homeostasis GO:0055080 195 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
alcohol metabolic process GO:0006066 77 0.017
blood vessel morphogenesis GO:0048514 58 0.017
organic acid transport GO:0015849 116 0.017
regulation of nervous system development GO:0051960 264 0.017
metal ion homeostasis GO:0055065 186 0.017
cardiovascular system development GO:0072358 134 0.017
developmental process involved in reproduction GO:0003006 159 0.017
peptidyl amino acid modification GO:0018193 126 0.017
gamete generation GO:0007276 124 0.017
regulation of cell migration GO:0030334 128 0.016
circulatory system development GO:0072359 134 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
regulation of ion transport GO:0043269 245 0.016
cellular component biogenesis GO:0044085 368 0.016
positive regulation of developmental process GO:0051094 283 0.016
response to estrogen GO:0043627 232 0.016
cellular chemical homeostasis GO:0055082 247 0.016
response to hexose GO:0009746 144 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
negative regulation of molecular function GO:0044092 133 0.015
response to decreased oxygen levels GO:0036293 237 0.015
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
immune response GO:0006955 104 0.015
regulation of apoptotic process GO:0042981 335 0.015
protein complex biogenesis GO:0070271 263 0.015
cellular carbohydrate metabolic process GO:0044262 72 0.015
nucleotide metabolic process GO:0009117 279 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
regulation of hormone levels GO:0010817 187 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
ras protein signal transduction GO:0007265 29 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
gland development GO:0048732 155 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
regulation of cellular component organization GO:0051128 368 0.015
cellular response to stress GO:0033554 269 0.015
regulation of cell development GO:0060284 263 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
positive regulation of nervous system development GO:0051962 178 0.015
calcium ion transport GO:0006816 131 0.015
regulation of immune system process GO:0002682 123 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
macromolecular complex subunit organization GO:0043933 339 0.014
maintenance of location GO:0051235 17 0.014
salivary gland development GO:0007431 3 0.014
response to hypoxia GO:0001666 231 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
positive regulation of cell development GO:0010720 176 0.014
regulation of anatomical structure size GO:0090066 135 0.014
response to radiation GO:0009314 137 0.014
regulation of neuron differentiation GO:0045664 208 0.014
dna metabolic process GO:0006259 96 0.014
negative regulation of gene expression GO:0010629 199 0.014
rna metabolic process GO:0016070 406 0.014
response to monosaccharide GO:0034284 159 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
cellular response to lipopolysaccharide GO:0071222 55 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
lipid biosynthetic process GO:0008610 128 0.014
membrane organization GO:0061024 94 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
head development GO:0060322 247 0.014
neuron development GO:0048666 286 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
negative regulation of transport GO:0051051 136 0.013
female pregnancy GO:0007565 122 0.013
negative regulation of signaling GO:0023057 157 0.013
b cell activation involved in immune response GO:0002312 1 0.013
cellular component assembly GO:0022607 360 0.013
reactive nitrogen species metabolic process GO:2001057 1 0.013
response to other organism GO:0051707 220 0.013
response to activity GO:0014823 73 0.013
response to growth factor GO:0070848 189 0.013
response to ethanol GO:0045471 162 0.013
regulation of protein kinase activity GO:0045859 105 0.013
positive regulation of gene expression GO:0010628 244 0.013
cytokine production GO:0001816 61 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
immune response to tumor cell GO:0002418 3 0.013
divalent inorganic cation transport GO:0072511 134 0.013
regulation of cellular localization GO:0060341 263 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
regulation of vasculature development GO:1901342 44 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
cell cell signaling GO:0007267 335 0.013
organ regeneration GO:0031100 101 0.013
response to insulin GO:0032868 133 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
regulation of cytokine production GO:0001817 56 0.013
response to amino acid GO:0043200 75 0.012
regulation of protein secretion GO:0050708 28 0.012
response to axon injury GO:0048678 59 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
regulation of transcription dna templated GO:0006355 374 0.012
positive regulation of immunoglobulin production GO:0002639 4 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
sterol homeostasis GO:0055092 3 0.012
anion transmembrane transport GO:0098656 77 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
transmembrane transport GO:0055085 412 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
response to tumor cell GO:0002347 4 0.012
regulation of response to tumor cell GO:0002834 3 0.012
wound healing GO:0042060 122 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
negative regulation of cell communication GO:0010648 158 0.012
small molecule catabolic process GO:0044282 59 0.012
metal ion transport GO:0030001 289 0.012
immune effector process GO:0002252 53 0.012
response to alkaloid GO:0043279 132 0.012
response to hyperoxia GO:0055093 45 0.012
cofactor metabolic process GO:0051186 95 0.012
positive regulation of transferase activity GO:0051347 81 0.012
regulation of immunoglobulin mediated immune response GO:0002889 2 0.012
regulation of cell projection organization GO:0031344 175 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
positive regulation of protein modification process GO:0031401 142 0.011
brain development GO:0007420 247 0.011
cell projection organization GO:0030030 302 0.011
cellular response to oxygen levels GO:0071453 60 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
multicellular organism growth GO:0035264 1 0.011
regulation of cell motility GO:2000145 131 0.011
neuron death GO:0070997 127 0.011
regulation of interferon gamma production GO:0032649 3 0.011
behavior GO:0007610 205 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
development of primary sexual characteristics GO:0045137 107 0.011
hormone metabolic process GO:0042445 69 0.011
blood vessel development GO:0001568 69 0.011
neurological system process GO:0050877 219 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
positive regulation of lipid metabolic process GO:0045834 33 0.011
male gamete generation GO:0048232 99 0.011
gastrulation GO:0007369 2 0.011
regulation of cell activation GO:0050865 50 0.011
cellular response to biotic stimulus GO:0071216 59 0.011
vasculature development GO:0001944 70 0.011
single organismal cell cell adhesion GO:0016337 42 0.011
regulation of membrane potential GO:0042391 110 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
protein oligomerization GO:0051259 191 0.011
vascular process in circulatory system GO:0003018 96 0.011
peptidyl tyrosine phosphorylation GO:0018108 72 0.011
multicellular organismal homeostasis GO:0048871 49 0.011
mapk cascade GO:0000165 140 0.011
regulation of system process GO:0044057 208 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
regulation of metal ion transport GO:0010959 118 0.011
cellular response to organic cyclic compound GO:0071407 202 0.010
regulation of b cell mediated immunity GO:0002712 2 0.010
regulation of establishment of protein localization GO:0070201 69 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
protein maturation GO:0051604 68 0.010
regulation of protein transport GO:0051223 68 0.010
purine containing compound metabolic process GO:0072521 253 0.010
response to vitamin GO:0033273 131 0.010
positive regulation of kinase activity GO:0033674 77 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
hormone secretion GO:0046879 115 0.010
response to corticosteroid GO:0031960 235 0.010
sex differentiation GO:0007548 113 0.010
regulation of cellular component movement GO:0051270 150 0.010
positive regulation of protein kinase activity GO:0045860 73 0.010
organelle organization GO:0006996 266 0.010
single organism organelle organization GO:1902589 180 0.010
positive regulation of b cell mediated immunity GO:0002714 2 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
positive regulation of transcription dna templated GO:0045893 197 0.010
organic anion transport GO:0015711 132 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
nitrogen compound transport GO:0071705 229 0.010
single organism intracellular transport GO:1902582 166 0.010
response to temperature stimulus GO:0009266 94 0.010
cellular response to hormone stimulus GO:0032870 247 0.010
fertilization GO:0009566 3 0.010
sulfur compound metabolic process GO:0006790 70 0.010
phospholipid metabolic process GO:0006644 61 0.010
hepaticobiliary system development GO:0061008 90 0.010

Spic disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012
central nervous system disease DOID:331 0 0.011