Rattus norvegicus

150 known processes

Uts2r

urotensin 2 receptor

(Aliases: Senr,Gpr14,UR-2-R)

Uts2r biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.374
regulation of nucleic acid templated transcription GO:1903506 380 0.371
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.325
regulation of rna metabolic process GO:0051252 391 0.237
positive regulation of biosynthetic process GO:0009891 319 0.217
transcription dna templated GO:0006351 377 0.162
transcription from rna polymerase ii promoter GO:0006366 252 0.157
negative regulation of nucleic acid templated transcription GO:1903507 117 0.151
gliogenesis GO:0042063 93 0.148
response to growth factor GO:0070848 189 0.141
regulation of molecular function GO:0065009 398 0.130
positive regulation of gene expression GO:0010628 244 0.130
macromolecular complex subunit organization GO:0043933 339 0.129
negative regulation of transcription dna templated GO:0045892 116 0.126
positive regulation of rna biosynthetic process GO:1902680 197 0.125
positive regulation of cellular biosynthetic process GO:0031328 295 0.119
cellular ketone metabolic process GO:0042180 51 0.116
regulation of rna biosynthetic process GO:2001141 381 0.115
response to inorganic substance GO:0010035 377 0.114
positive regulation of transcription dna templated GO:0045893 197 0.112
regulation of cellular protein metabolic process GO:0032268 267 0.109
nucleic acid templated transcription GO:0097659 379 0.107
regulation of transcription dna templated GO:0006355 374 0.106
response to hypoxia GO:0001666 231 0.106
cellular response to acid chemical GO:0071229 75 0.101
apoptotic process GO:0006915 381 0.098
cell migration GO:0016477 197 0.097
response to retinoic acid GO:0032526 63 0.096
cell motility GO:0048870 202 0.095
regulation of cellular ketone metabolic process GO:0010565 27 0.095
response to acid chemical GO:0001101 222 0.094
multi organism reproductive process GO:0044703 262 0.093
Worm
positive regulation of rna metabolic process GO:0051254 203 0.093
regulation of programmed cell death GO:0043067 341 0.092
reproduction GO:0000003 245 0.090
Worm
cell type specific apoptotic process GO:0097285 134 0.090
pancreatic stellate cell proliferation GO:0072343 2 0.089
regulation of signal transduction GO:0009966 318 0.087
response to metal ion GO:0010038 253 0.087
locomotion GO:0040011 237 0.086
Worm
defense response GO:0006952 194 0.082
regulation of apoptotic process GO:0042981 335 0.082
single organism reproductive process GO:0044702 297 0.081
Worm
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.081
positive regulation of immunoglobulin production GO:0002639 4 0.079
nucleobase containing small molecule metabolic process GO:0055086 316 0.078
negative regulation of multicellular organismal process GO:0051241 203 0.077
positive regulation of phosphorus metabolic process GO:0010562 262 0.076
regulation of locomotion GO:0040012 148 0.075
organic acid metabolic process GO:0006082 292 0.074
glial cell differentiation GO:0010001 65 0.074
positive regulation of nucleic acid templated transcription GO:1903508 197 0.072
positive regulation of signaling GO:0023056 270 0.072
regulation of phosphate metabolic process GO:0019220 349 0.071
programmed cell death GO:0012501 392 0.071
sexual reproduction GO:0019953 148 0.070
Worm
response to wounding GO:0009611 254 0.069
negative regulation of cell differentiation GO:0045596 99 0.068
regulation of multicellular organismal development GO:2000026 376 0.068
regulation of protein metabolic process GO:0051246 289 0.068
cation transport GO:0006812 382 0.067
organic anion transport GO:0015711 132 0.066
oxoacid metabolic process GO:0043436 290 0.065
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.065
sensory organ development GO:0007423 74 0.065
response to nutrient levels GO:0031667 370 0.064
negative regulation of cellular biosynthetic process GO:0031327 161 0.063
positive regulation of protein phosphorylation GO:0001934 135 0.063
reproductive process GO:0022414 372 0.062
Worm
head development GO:0060322 247 0.062
organophosphate biosynthetic process GO:0090407 143 0.062
negative regulation of gene expression GO:0010629 199 0.061
response to radiation GO:0009314 137 0.061
negative regulation of biosynthetic process GO:0009890 168 0.061
response to oxygen levels GO:0070482 265 0.060
carboxylic acid metabolic process GO:0019752 289 0.060
positive regulation of protein modification process GO:0031401 142 0.059
rna metabolic process GO:0016070 406 0.058
negative regulation of macromolecule metabolic process GO:0010605 260 0.057
regulation of ion transport GO:0043269 245 0.057
cellular response to cytokine stimulus GO:0071345 127 0.057
response to extracellular stimulus GO:0009991 380 0.056
positive regulation of protein metabolic process GO:0051247 178 0.056
chemical homeostasis GO:0048878 292 0.056
regulation of phosphorylation GO:0042325 248 0.055
localization of cell GO:0051674 202 0.055
single organism biosynthetic process GO:0044711 342 0.053
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.053
brain development GO:0007420 247 0.052
organophosphate metabolic process GO:0019637 370 0.052
protein localization GO:0008104 191 0.052
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.052
negative regulation of rna biosynthetic process GO:1902679 118 0.051
regulation of immunoglobulin production GO:0002637 4 0.051
ribonucleotide metabolic process GO:0009259 231 0.051
cellular response to lipid GO:0071396 201 0.051
negative regulation of developmental process GO:0051093 125 0.050
protein complex subunit organization GO:0071822 302 0.050
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.050
response to estrogen GO:0043627 232 0.049
protein complex assembly GO:0006461 263 0.049
cellular component movement GO:0006928 248 0.049
cellular homeostasis GO:0019725 252 0.049
catabolic process GO:0009056 351 0.049
regulation of protein phosphorylation GO:0001932 183 0.049
regulation of cell differentiation GO:0045595 320 0.048
homeostatic process GO:0042592 331 0.047
carbohydrate derivative metabolic process GO:1901135 346 0.047
tissue development GO:0009888 252 0.047
response to decreased oxygen levels GO:0036293 237 0.047
macromolecular complex assembly GO:0065003 273 0.047
regulation of phosphorus metabolic process GO:0051174 349 0.047
regulation of anatomical structure size GO:0090066 135 0.045
regulation of neuron differentiation GO:0045664 208 0.044
epithelial cell differentiation GO:0030855 71 0.044
nucleotide metabolic process GO:0009117 279 0.043
response to nutrient GO:0007584 248 0.043
response to ionizing radiation GO:0010212 59 0.043
positive regulation of programmed cell death GO:0043068 157 0.043
protein complex biogenesis GO:0070271 263 0.042
behavior GO:0007610 205 0.042
regulation of secretion GO:0051046 224 0.042
central nervous system development GO:0007417 311 0.041
reproductive system development GO:0061458 128 0.041
negative regulation of metabolic process GO:0009892 331 0.041
cellular response to growth factor stimulus GO:0071363 162 0.040
regulation of cellular amino acid metabolic process GO:0006521 2 0.040
multi multicellular organism process GO:0044706 138 0.039
establishment of protein localization GO:0045184 141 0.039
protein oligomerization GO:0051259 191 0.039
response to estradiol GO:0032355 164 0.039
regulation of cell development GO:0060284 263 0.039
organ morphogenesis GO:0009887 75 0.038
aging GO:0007568 241 0.038
regulation of cell motility GO:2000145 131 0.038
positive regulation of secretion by cell GO:1903532 128 0.037
cytokine mediated signaling pathway GO:0019221 43 0.037
positive regulation of phosphate metabolic process GO:0045937 262 0.037
intracellular signal transduction GO:0035556 314 0.037
cellular response to retinoic acid GO:0071300 27 0.037
lipid metabolic process GO:0006629 283 0.036
organic substance catabolic process GO:1901575 316 0.035
positive regulation of transport GO:0051050 245 0.035
anterior posterior pattern specification GO:0009952 1 0.035
response to vitamin GO:0033273 131 0.035
wound healing GO:0042060 122 0.034
multicellular organismal reproductive process GO:0048609 233 0.034
Worm
regulation of intracellular signal transduction GO:1902531 218 0.034
positive regulation of phosphorylation GO:0042327 177 0.033
regulation of cellular component movement GO:0051270 150 0.033
dna metabolic process GO:0006259 96 0.033
neuron differentiation GO:0030182 368 0.033
macromolecule localization GO:0033036 252 0.032
positive regulation of apoptotic process GO:0043065 154 0.032
n methyl d aspartate receptor clustering GO:0097114 2 0.031
cellular amino acid metabolic process GO:0006520 107 0.030
purine ribonucleoside metabolic process GO:0046128 168 0.030
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.030
cellular component biogenesis GO:0044085 368 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.029
regulation of response to stress GO:0080134 126 0.029
protein transport GO:0015031 132 0.029
cation homeostasis GO:0055080 195 0.029
response to ketone GO:1901654 182 0.029
organonitrogen compound biosynthetic process GO:1901566 167 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.029
positive regulation of cell development GO:0010720 176 0.029
single organism behavior GO:0044708 130 0.029
cation transmembrane transport GO:0098655 263 0.029
cellular lipid metabolic process GO:0044255 208 0.028
response to nicotine GO:0035094 51 0.028
purine nucleotide metabolic process GO:0006163 229 0.028
positive regulation of secretion GO:0051047 140 0.028
cellular metal ion homeostasis GO:0006875 172 0.028
negative regulation of molecular function GO:0044092 133 0.028
camp metabolic process GO:0046058 63 0.028
regulation of nucleotide metabolic process GO:0006140 117 0.027
gonad development GO:0008406 104 0.027
rhythmic process GO:0048511 156 0.027
regulation of neuron death GO:1901214 115 0.027
inflammatory response GO:0006954 150 0.027
cellular amine metabolic process GO:0044106 38 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.027
glycosyl compound metabolic process GO:1901657 182 0.027
regulation of nervous system development GO:0051960 264 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
negative regulation of membrane potential GO:0045837 5 0.027
response to mechanical stimulus GO:0009612 134 0.027
regulation of cellular component organization GO:0051128 368 0.027
regulation of protein modification process GO:0031399 194 0.026
anion transport GO:0006820 178 0.026
circadian rhythm GO:0007623 88 0.026
positive regulation of signal transduction GO:0009967 175 0.026
cellular protein localization GO:0034613 122 0.026
negative regulation of cell death GO:0060548 229 0.026
positive regulation of nucleotide metabolic process GO:0045981 91 0.026
negative regulation of apoptotic process GO:0043066 181 0.026
cell cell signaling GO:0007267 335 0.025
g protein coupled receptor signaling pathway GO:0007186 242 0.025
epithelium development GO:0060429 96 0.025
cellular response to stress GO:0033554 269 0.025
regulation of neuron projection development GO:0010975 161 0.025
response to testosterone GO:0033574 55 0.025
cellular response to oxygen containing compound GO:1901701 386 0.024
response to ethanol GO:0045471 162 0.024
regulation of acute inflammatory response GO:0002673 23 0.024
positive regulation of cell death GO:0010942 184 0.024
membrane organization GO:0061024 94 0.024
reproductive structure development GO:0048608 128 0.024
organ formation GO:0048645 3 0.024
regulation of cell proliferation GO:0042127 359 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
response to external biotic stimulus GO:0043207 221 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
regulation of neurogenesis GO:0050767 247 0.023
cellular nitrogen compound catabolic process GO:0044270 163 0.022
response to molecule of bacterial origin GO:0002237 194 0.022
regulation of cellular localization GO:0060341 263 0.022
positive regulation of nervous system development GO:0051962 178 0.022
cell projection organization GO:0030030 302 0.022
intracellular protein transport GO:0006886 79 0.022
peptidyl amino acid modification GO:0018193 126 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
mapk cascade GO:0000165 140 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
transmembrane transport GO:0055085 412 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.021
response to amino acid GO:0043200 75 0.021
development of primary sexual characteristics GO:0045137 107 0.021
positive regulation of locomotion GO:0040017 102 0.021
negative regulation of rna metabolic process GO:0051253 123 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
male sex differentiation GO:0046661 64 0.020
cytosolic calcium ion homeostasis GO:0051480 140 0.020
muscle system process GO:0003012 115 0.020
positive regulation of molecular function GO:0044093 230 0.020
multicellular organism reproduction GO:0032504 233 0.020
Worm
regulation of cell migration GO:0030334 128 0.020
cellular macromolecule localization GO:0070727 122 0.020
anatomical structure morphogenesis GO:0009653 298 0.020
muscle structure development GO:0061061 87 0.020
positive regulation of response to stimulus GO:0048584 285 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
neuromuscular synaptic transmission GO:0007274 2 0.019
protein phosphorylation GO:0006468 345 0.019
purine containing compound metabolic process GO:0072521 253 0.019
positive regulation of long term synaptic potentiation GO:1900273 4 0.019
negative regulation of signal transduction GO:0009968 83 0.019
embryonic pattern specification GO:0009880 1 0.019
nucleotide biosynthetic process GO:0009165 98 0.019
comma shaped body morphogenesis GO:0072049 2 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
circadian sleep wake cycle wakefulness GO:0042746 2 0.018
organic acid transport GO:0015849 116 0.018
response to oxidative stress GO:0006979 186 0.018
cellular ion homeostasis GO:0006873 184 0.018
response to lipopolysaccharide GO:0032496 191 0.018
regeneration GO:0031099 163 0.018
regulation of muscle organ development GO:0048634 26 0.018
sex differentiation GO:0007548 113 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
regulation of muscle tissue development GO:1901861 25 0.018
intracellular transport GO:0046907 185 0.017
single organism membrane organization GO:0044802 74 0.017
eye development GO:0001654 50 0.017
positive regulation of cell communication GO:0010647 271 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
nucleoside phosphate biosynthetic process GO:1901293 102 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
forebrain development GO:0030900 98 0.017
single organism intracellular transport GO:1902582 166 0.017
response to temperature stimulus GO:0009266 94 0.016
positive regulation of circadian sleep wake cycle wakefulness GO:0010841 2 0.016
phospholipid metabolic process GO:0006644 61 0.016
regulation of pancreatic stellate cell proliferation GO:2000229 2 0.016
metal ion homeostasis GO:0055065 186 0.016
regulation of kinase activity GO:0043549 117 0.016
regulation of catalytic activity GO:0050790 304 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
negative regulation of nervous system development GO:0051961 79 0.016
negative regulation of neurogenesis GO:0050768 78 0.016
divalent metal ion transport GO:0070838 132 0.016
positive regulation of inflammatory response GO:0050729 24 0.016
female pregnancy GO:0007565 122 0.016
synaptic transmission GO:0007268 235 0.016
response to reactive oxygen species GO:0000302 120 0.015
circulatory system process GO:0003013 183 0.015
camp biosynthetic process GO:0006171 47 0.015
negative regulation of acute inflammatory response GO:0002674 4 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
response to bacterium GO:0009617 200 0.015
positive regulation of cellular component biogenesis GO:0044089 55 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
response to other organism GO:0051707 220 0.015
response to cytokine GO:0034097 215 0.015
carbohydrate metabolic process GO:0005975 130 0.015
positive regulation of cell migration GO:0030335 96 0.015
gamete generation GO:0007276 124 0.015
Worm
rna biosynthetic process GO:0032774 380 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.014
amine metabolic process GO:0009308 38 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
s shaped body morphogenesis GO:0072050 2 0.014
hemopoiesis GO:0030097 34 0.014
regulation of circadian sleep wake cycle wakefulness GO:0010840 2 0.014
calcium ion transport GO:0006816 131 0.014
motor neuron axon guidance GO:0008045 1 0.014
regulation of camp biosynthetic process GO:0030817 38 0.014
positive regulation of camp metabolic process GO:0030816 31 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
cellular cation homeostasis GO:0030003 180 0.014
regulation of developmental growth GO:0048638 45 0.013
cytokine production GO:0001816 61 0.013
nucleotide catabolic process GO:0009166 139 0.013
endocytosis GO:0006897 84 0.013
multicellular organism growth GO:0035264 1 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
protein targeting GO:0006605 61 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
epiboly involved in wound healing GO:0090505 2 0.013
carboxylic acid transport GO:0046942 115 0.013
spermatogenesis GO:0007283 99 0.013
unsaturated fatty acid metabolic process GO:0033559 39 0.013
purine containing compound catabolic process GO:0072523 138 0.013
muscle cell differentiation GO:0042692 52 0.013
oligodendrocyte differentiation GO:0048709 32 0.013
monocarboxylic acid transport GO:0015718 52 0.013
cellular response to vitamin e GO:0071306 3 0.013
proteolysis GO:0006508 175 0.013
immune system process GO:0002376 204 0.013
regulation of dna metabolic process GO:0051052 60 0.013
t cell activation GO:0042110 29 0.012
circulatory system development GO:0072359 134 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
ribonucleotide biosynthetic process GO:0009260 85 0.012
development of primary male sexual characteristics GO:0046546 59 0.012
jak stat cascade GO:0007259 26 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
positive regulation of camp biosynthetic process GO:0030819 28 0.012
response to purine containing compound GO:0014074 126 0.012
developmental process involved in reproduction GO:0003006 159 0.012
Worm
cognition GO:0050890 92 0.012
leukocyte differentiation GO:0002521 30 0.012
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
regulation of cellular response to stress GO:0080135 49 0.012
cell morphogenesis GO:0000902 142 0.012
multicellular organismal homeostasis GO:0048871 49 0.012
growth GO:0040007 165 0.012
regulation of organ growth GO:0046620 13 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
neuron death GO:0070997 127 0.012
cellular component assembly GO:0022607 360 0.012
cyclic nucleotide biosynthetic process GO:0009190 63 0.012
somatostatin signaling pathway GO:0038170 4 0.012
icosanoid metabolic process GO:0006690 38 0.011
regulation of vasculature development GO:1901342 44 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
acid secretion GO:0046717 48 0.011
dendrite development GO:0016358 72 0.011
metal ion transport GO:0030001 289 0.011
angiogenesis GO:0001525 53 0.011
regulation of mapk cascade GO:0043408 116 0.011
negative regulation of glutamate secretion GO:0014050 9 0.011
hippocampus development GO:0021766 30 0.011
cellular response to interleukin 1 GO:0071347 37 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
regulation of synaptic transmission GO:0050804 141 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
acute inflammatory response GO:0002526 58 0.011
gland development GO:0048732 155 0.011
eye morphogenesis GO:0048592 4 0.011
cell growth GO:0016049 104 0.011
somatostatin receptor signaling pathway GO:0038169 4 0.011
fatty acid derivative metabolic process GO:1901568 38 0.011
carboxylic acid biosynthetic process GO:0046394 83 0.011
response to carbohydrate GO:0009743 183 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
organ regeneration GO:0031100 101 0.011
neuron projection development GO:0031175 273 0.011
regulation of response to wounding GO:1903034 69 0.011
positive regulation of cytokine production GO:0001819 42 0.011
response to hyperoxia GO:0055093 45 0.011
dna replication GO:0006260 37 0.011
response to tumor necrosis factor GO:0034612 56 0.011
amino acid transport GO:0006865 70 0.010
muscle cell proliferation GO:0033002 84 0.010
negative regulation of cell development GO:0010721 82 0.010
protein homooligomerization GO:0051260 91 0.010
digestive tract development GO:0048565 39 0.010
positive regulation of response to food GO:0032097 3 0.010
chemosensory behavior GO:0007635 2 0.010
urogenital system development GO:0001655 78 0.010
odontogenesis GO:0042476 32 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
cytoplasmic transport GO:0016482 115 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
regulation of hydrolase activity GO:0051336 143 0.010
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.010

Uts2r disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.055
disease of anatomical entity DOID:7 0 0.055
eye and adnexa disease DOID:1492 0 0.055
nervous system disease DOID:863 0 0.055
retinal disease DOID:5679 0 0.021
eye disease DOID:5614 0 0.021
musculoskeletal system disease DOID:17 0 0.014
urinary system disease DOID:18 0 0.012
cardiovascular system disease DOID:1287 0 0.012
blindness DOID:1432 0 0.011
kidney disease DOID:557 0 0.011
nephrogenic diabetes insipidus DOID:12387 0 0.011
impaired renal function disease DOID:11705 0 0.011