Rattus norvegicus

0 known processes

Ckmt2

creatine kinase, mitochondrial 2, sarcomeric

(Aliases: MGC187999)

Ckmt2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle system process GO:0003012 115 0.252
slow twitch skeletal muscle fiber contraction GO:0031444 2 0.247
striated muscle contraction GO:0006941 44 0.208
muscle contraction GO:0006936 88 0.168
cardiac muscle contraction GO:0060048 27 0.152
actin myosin filament sliding GO:0033275 2 0.151
cold acclimation GO:0009631 1 0.129
cardiac muscle tissue morphogenesis GO:0055008 1 0.113
catabolic process GO:0009056 351 0.113
carboxylic acid metabolic process GO:0019752 289 0.092
cellular catabolic process GO:0044248 295 0.082
organic substance catabolic process GO:1901575 316 0.079
single organism catabolic process GO:0044712 283 0.078
muscle filament sliding GO:0030049 2 0.068
cellular component assembly GO:0022607 360 0.066
response to inorganic substance GO:0010035 377 0.066
reproduction GO:0000003 245 0.065
organic acid metabolic process GO:0006082 292 0.062
cellular component biogenesis GO:0044085 368 0.061
homeostatic process GO:0042592 331 0.060
cardiac myofibril assembly GO:0055003 1 0.056
actin filament based movement GO:0030048 16 0.055
heart morphogenesis GO:0003007 3 0.054
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.053
response to heat GO:0009408 60 0.051
cellular modified amino acid metabolic process GO:0006575 61 0.050
response to metal ion GO:0010038 253 0.050
circulatory system process GO:0003013 183 0.049
response to estrogen GO:0043627 232 0.048
blood circulation GO:0008015 183 0.048
cell projection organization GO:0030030 302 0.048
nucleotide metabolic process GO:0009117 279 0.047
cellular component morphogenesis GO:0032989 155 0.046
actin mediated cell contraction GO:0070252 12 0.045
carbohydrate derivative metabolic process GO:1901135 346 0.043
positive regulation of developmental process GO:0051094 283 0.043
aromatic compound catabolic process GO:0019439 168 0.042
actin filament based process GO:0030029 86 0.042
negative regulation of multicellular organismal process GO:0051241 203 0.041
regulation of ion transport GO:0043269 245 0.041
protein complex biogenesis GO:0070271 263 0.041
muscle structure development GO:0061061 87 0.040
cell cell signaling GO:0007267 335 0.040
muscle tissue development GO:0060537 58 0.040
negative regulation of cell death GO:0060548 229 0.039
oxidation reduction process GO:0055114 304 0.039
response to oxidative stress GO:0006979 186 0.039
regulation of muscle contraction GO:0006937 53 0.037
monocarboxylic acid metabolic process GO:0032787 152 0.037
intracellular signal transduction GO:0035556 314 0.037
generation of precursor metabolites and energy GO:0006091 62 0.036
organophosphate metabolic process GO:0019637 370 0.035
regulation of system process GO:0044057 208 0.035
cellular chemical homeostasis GO:0055082 247 0.035
heart development GO:0007507 72 0.035
heterocycle catabolic process GO:0046700 167 0.035
anatomical structure formation involved in morphogenesis GO:0048646 83 0.034
protein complex subunit organization GO:0071822 302 0.033
muscle cell differentiation GO:0042692 52 0.033
ventricular cardiac muscle cell action potential GO:0086005 2 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.033
positive regulation of transport GO:0051050 245 0.033
carbohydrate derivative catabolic process GO:1901136 147 0.032
nucleoside catabolic process GO:0009164 126 0.032
response to growth factor GO:0070848 189 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
negative regulation of apoptotic process GO:0043066 181 0.030
negative regulation of programmed cell death GO:0043069 183 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
single organism organelle organization GO:1902589 180 0.030
response to reactive oxygen species GO:0000302 120 0.030
regulation of cellular localization GO:0060341 263 0.030
cellular amino acid metabolic process GO:0006520 107 0.030
negative regulation of metabolic process GO:0009892 331 0.030
regulation of nucleic acid templated transcription GO:1903506 380 0.029
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.029
regulation of molecular function GO:0065009 398 0.029
response to oxygen levels GO:0070482 265 0.029
heart contraction GO:0060047 57 0.029
regulation of cell development GO:0060284 263 0.029
organelle organization GO:0006996 266 0.028
regulation of rna metabolic process GO:0051252 391 0.028
protein oligomerization GO:0051259 191 0.028
circulatory system development GO:0072359 134 0.028
secretion by cell GO:0032940 248 0.028
response to mechanical stimulus GO:0009612 134 0.027
immune system process GO:0002376 204 0.027
defense response GO:0006952 194 0.027
muscle organ morphogenesis GO:0048644 1 0.027
organophosphate catabolic process GO:0046434 148 0.027
organonitrogen compound catabolic process GO:1901565 179 0.026
twitch skeletal muscle contraction GO:0014721 3 0.026
glycosyl compound metabolic process GO:1901657 182 0.026
response to decreased oxygen levels GO:0036293 237 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
positive regulation of signal transduction GO:0009967 175 0.026
cellular amine metabolic process GO:0044106 38 0.026
positive regulation of ion transport GO:0043270 94 0.025
protein complex assembly GO:0006461 263 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.025
regulation of cell differentiation GO:0045595 320 0.025
heart process GO:0003015 57 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
ribonucleoside triphosphate metabolic process GO:0009199 141 0.025
negative regulation of gene expression GO:0010629 199 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
secretion GO:0046903 307 0.024
erythrocyte differentiation GO:0030218 1 0.024
cellular nitrogen compound catabolic process GO:0044270 163 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
purine nucleoside monophosphate catabolic process GO:0009128 55 0.024
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 3 0.024
macromolecular complex assembly GO:0065003 273 0.024
chemical homeostasis GO:0048878 292 0.024
purine containing compound catabolic process GO:0072523 138 0.024
divalent inorganic cation homeostasis GO:0072507 165 0.024
response to hypoxia GO:0001666 231 0.023
skeletal muscle contraction GO:0003009 17 0.023
rna metabolic process GO:0016070 406 0.023
cellular component movement GO:0006928 248 0.023
organic cyclic compound catabolic process GO:1901361 175 0.023
single organism biosynthetic process GO:0044711 342 0.022
cellular macromolecule localization GO:0070727 122 0.022
amine metabolic process GO:0009308 38 0.022
ribonucleoside metabolic process GO:0009119 174 0.022
cell projection morphogenesis GO:0048858 123 0.022
nucleoside metabolic process GO:0009116 179 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.022
rna biosynthetic process GO:0032774 380 0.021
nucleobase containing compound catabolic process GO:0034655 152 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
glycosyl compound catabolic process GO:1901658 126 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
cellular homeostasis GO:0019725 252 0.021
organic hydroxy compound metabolic process GO:1901615 115 0.021
cardiac muscle cell action potential involved in contraction GO:0086002 2 0.021
cardiovascular system development GO:0072358 134 0.021
negative regulation of transport GO:0051051 136 0.021
neuron differentiation GO:0030182 368 0.021
multicellular organism reproduction GO:0032504 233 0.021
cellular protein localization GO:0034613 122 0.021
positive regulation of cellular component organization GO:0051130 200 0.020
regulation of cell proliferation GO:0042127 359 0.020
oxoacid metabolic process GO:0043436 290 0.020
programmed cell death GO:0012501 392 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.020
neuron development GO:0048666 286 0.020
purine containing compound metabolic process GO:0072521 253 0.020
regulation of programmed cell death GO:0043067 341 0.020
cellular response to oxygen containing compound GO:1901701 386 0.020
response to temperature stimulus GO:0009266 94 0.020
response to other organism GO:0051707 220 0.020
cytosolic calcium ion homeostasis GO:0051480 140 0.019
protein tetramerization GO:0051262 38 0.019
regulation of muscle system process GO:0090257 79 0.019
transcription dna templated GO:0006351 377 0.019
purine nucleoside metabolic process GO:0042278 169 0.019
cellular ion homeostasis GO:0006873 184 0.019
response to peptide GO:1901652 292 0.019
regulation of apoptotic process GO:0042981 335 0.019
voluntary skeletal muscle contraction GO:0003010 3 0.019
apoptotic process GO:0006915 381 0.019
response to nutrient levels GO:0031667 370 0.019
cellular metal ion homeostasis GO:0006875 172 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
regulation of catabolic process GO:0009894 113 0.019
response to peptide hormone GO:0043434 278 0.019
cellular ketone metabolic process GO:0042180 51 0.019
response to carbohydrate GO:0009743 183 0.019
cardiac ventricle development GO:0003231 1 0.018
macromolecule localization GO:0033036 252 0.018
lipid metabolic process GO:0006629 283 0.018
head development GO:0060322 247 0.018
regulation of signal transduction GO:0009966 318 0.018
negative regulation of cell communication GO:0010648 158 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
regulation of neuron projection development GO:0010975 161 0.018
response to bacterium GO:0009617 200 0.017
cardiac chamber development GO:0003205 1 0.017
atp metabolic process GO:0046034 72 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
multi organism reproductive process GO:0044703 262 0.017
nucleoside phosphate catabolic process GO:1901292 140 0.017
ribonucleoside monophosphate metabolic process GO:0009161 88 0.017
cation homeostasis GO:0055080 195 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
response to monosaccharide GO:0034284 159 0.017
proteolysis GO:0006508 175 0.017
adult locomotory behavior GO:0008344 4 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
nucleotide catabolic process GO:0009166 139 0.017
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.017
response to extracellular stimulus GO:0009991 380 0.017
neuron projection morphogenesis GO:0048812 122 0.017
regulation of striated muscle contraction GO:0006942 21 0.017
nucleoside monophosphate metabolic process GO:0009123 93 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
cytoskeleton organization GO:0007010 111 0.016
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.016
lipid biosynthetic process GO:0008610 128 0.016
immune response GO:0006955 104 0.016
peptide hormone secretion GO:0030072 84 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
hexose biosynthetic process GO:0019319 15 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
ribonucleoside catabolic process GO:0042454 126 0.016
gamete generation GO:0007276 124 0.016
regulation of cellular component organization GO:0051128 368 0.016
enzyme linked receptor protein signaling pathway GO:0007167 116 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
reproductive process GO:0022414 372 0.016
nucleic acid templated transcription GO:0097659 379 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.015
carbohydrate catabolic process GO:0016052 40 0.015
aging GO:0007568 241 0.015
central nervous system development GO:0007417 311 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
negative regulation of molecular function GO:0044092 133 0.015
reactive oxygen species metabolic process GO:0072593 37 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
single organism carbohydrate catabolic process GO:0044724 40 0.015
purine nucleoside monophosphate metabolic process GO:0009126 84 0.015
single organism reproductive process GO:0044702 297 0.015
sequestering of triglyceride GO:0030730 1 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
response to radiation GO:0009314 137 0.015
cellular response to stress GO:0033554 269 0.015
neuron projection development GO:0031175 273 0.015
signal release GO:0023061 145 0.015
response to calcium ion GO:0051592 59 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
axon development GO:0061564 96 0.015
carbohydrate biosynthetic process GO:0016051 42 0.015
nucleoside monophosphate catabolic process GO:0009125 56 0.015
regulation of hormone levels GO:0010817 187 0.015
response to biotic stimulus GO:0009607 226 0.015
regulation of neuron differentiation GO:0045664 208 0.015
negative regulation of signaling GO:0023057 157 0.014
regulation of membrane potential GO:0042391 110 0.014
striated muscle tissue development GO:0014706 58 0.014
carbohydrate metabolic process GO:0005975 130 0.014
vesicle mediated transport GO:0016192 181 0.014
response to hydrogen peroxide GO:0042542 89 0.014
anterior posterior pattern specification GO:0009952 1 0.014
calcium ion homeostasis GO:0055074 162 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
striated muscle cell development GO:0055002 26 0.014
actin cytoskeleton organization GO:0030036 73 0.014
regulation of mapk cascade GO:0043408 116 0.014
cell growth GO:0016049 104 0.014
response to hexose GO:0009746 144 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
maintenance of location GO:0051235 17 0.014
response to wounding GO:0009611 254 0.013
syncytium formation by plasma membrane fusion GO:0000768 3 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
nucleoside triphosphate catabolic process GO:0009143 123 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
positive regulation of cell communication GO:0010647 271 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
metal ion transport GO:0030001 289 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
response to external biotic stimulus GO:0043207 221 0.013
regulation of metal ion transport GO:0010959 118 0.013
cardiocyte differentiation GO:0035051 22 0.013
regulation of response to stress GO:0080134 126 0.013
regulation of hormone secretion GO:0046883 106 0.013
endoplasmic reticulum to cytosol transport GO:1903513 4 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
regulation of transcription dna templated GO:0006355 374 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
regulation of phosphate metabolic process GO:0019220 349 0.012
intracellular transport GO:0046907 185 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
response to glucose GO:0009749 136 0.012
regulation of phosphorylation GO:0042325 248 0.012
single organism intracellular transport GO:1902582 166 0.012
regulation of nervous system development GO:0051960 264 0.012
spermatogenesis GO:0007283 99 0.012
positive regulation of nervous system development GO:0051962 178 0.012
hormone secretion GO:0046879 115 0.012
cellular component assembly involved in morphogenesis GO:0010927 17 0.012
response to ethanol GO:0045471 162 0.012
positive regulation of signaling GO:0023056 270 0.012
myeloid cell differentiation GO:0030099 22 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
alcohol metabolic process GO:0006066 77 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
positive regulation of cell development GO:0010720 176 0.012
brain development GO:0007420 247 0.012
growth GO:0040007 165 0.012
negative regulation of potassium ion transmembrane transport GO:1901380 3 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
sequestering of calcium ion GO:0051208 8 0.012
regulation of cell projection organization GO:0031344 175 0.012
regulation of protein metabolic process GO:0051246 289 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
response to estradiol GO:0032355 164 0.012
erk1 and erk2 cascade GO:0070371 48 0.012
positive regulation of molecular function GO:0044093 230 0.012
atp catabolic process GO:0006200 54 0.011
axis specification GO:0009798 4 0.011
single organism behavior GO:0044708 130 0.011
protein homooligomerization GO:0051260 91 0.011
developmental growth GO:0048589 100 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
syncytium formation GO:0006949 4 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
response to corticosteroid GO:0031960 235 0.011
cardiac conduction GO:0061337 2 0.011
erythrocyte homeostasis GO:0034101 2 0.011
response to lipopolysaccharide GO:0032496 191 0.011
response to transforming growth factor beta GO:0071559 46 0.011
cytokinetic process GO:0032506 1 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
axonogenesis GO:0007409 71 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
cellular cation homeostasis GO:0030003 180 0.011
hormone metabolic process GO:0042445 69 0.011
regulation of cytokine production GO:0001817 56 0.011
regulation of hydrolase activity GO:0051336 143 0.011
cardiac muscle cell development GO:0055013 16 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
bmp signaling pathway GO:0030509 4 0.011
cellular amino acid biosynthetic process GO:0008652 32 0.011
synaptic transmission GO:0007268 235 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
male gamete generation GO:0048232 99 0.011
positive regulation of cell proliferation GO:0008284 249 0.010
cardiac muscle cell contraction GO:0086003 10 0.010
response to nutrient GO:0007584 248 0.010
cation transport GO:0006812 382 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
response to electrical stimulus GO:0051602 56 0.010
transcription from rna polymerase ii promoter GO:0006366 252 0.010
regulation of interferon gamma production GO:0032649 3 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
muscle tissue morphogenesis GO:0060415 1 0.010
myoblast fusion GO:0007520 2 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
sequestering of metal ion GO:0051238 9 0.010
metal ion homeostasis GO:0055065 186 0.010
peptide transport GO:0015833 97 0.010
developmental process involved in reproduction GO:0003006 159 0.010
regulation of catalytic activity GO:0050790 304 0.010
membrane organization GO:0061024 94 0.010
calcium ion transport GO:0006816 131 0.010
cell part morphogenesis GO:0032990 123 0.010

Ckmt2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.319
muscular disease DOID:0080000 0 0.319
heart disease DOID:114 0 0.319
cardiomyopathy DOID:0050700 0 0.319
disease of anatomical entity DOID:7 0 0.319
intrinsic cardiomyopathy DOID:0060036 0 0.319
cardiovascular system disease DOID:1287 0 0.319
musculoskeletal system disease DOID:17 0 0.319
muscle tissue disease DOID:66 0 0.319
dilated cardiomyopathy DOID:12930 0 0.078
hypertrophic cardiomyopathy DOID:11984 0 0.075
congenital heart disease DOID:1682 0 0.029
heart septal defect DOID:1681 0 0.029
disease of metabolism DOID:0014667 0 0.029