Rattus norvegicus

52 known processes

Xdh

xanthine dehydrogenase

(Aliases: XOR)

Xdh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to biotic stimulus GO:0009607 226 0.547
response to other organism GO:0051707 220 0.493
immunoglobulin mediated immune response GO:0016064 4 0.265
rna biosynthetic process GO:0032774 380 0.259
response to external biotic stimulus GO:0043207 221 0.249
cellular response to oxygen containing compound GO:1901701 386 0.226
rna metabolic process GO:0016070 406 0.224
negative regulation of metabolic process GO:0009892 331 0.201
Human
single organism biosynthetic process GO:0044711 342 0.188
response to bacterium GO:0009617 200 0.181
response to lipopolysaccharide GO:0032496 191 0.157
fatty acid metabolic process GO:0006631 99 0.155
regulation of cell proliferation GO:0042127 359 0.145
Human
lipid metabolic process GO:0006629 283 0.140
organic substance catabolic process GO:1901575 316 0.126
defense response GO:0006952 194 0.122
lipid biosynthetic process GO:0008610 128 0.122
immune system process GO:0002376 204 0.122
regulation of cytokine production GO:0001817 56 0.119
cellular response to lipid GO:0071396 201 0.114
organic acid metabolic process GO:0006082 292 0.113
regulation of rna metabolic process GO:0051252 391 0.103
carboxylic acid metabolic process GO:0019752 289 0.103
oxoacid metabolic process GO:0043436 290 0.094
response to inorganic substance GO:0010035 377 0.091
icosanoid metabolic process GO:0006690 38 0.090
response to metal ion GO:0010038 253 0.089
regulation of transcription dna templated GO:0006355 374 0.089
cytokine biosynthetic process GO:0042089 3 0.087
cellular response to organic cyclic compound GO:0071407 202 0.086
regulation of nucleic acid templated transcription GO:1903506 380 0.081
positive regulation of transcription dna templated GO:0045893 197 0.079
unsaturated fatty acid metabolic process GO:0033559 39 0.078
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.077
nucleic acid templated transcription GO:0097659 379 0.076
transcription dna templated GO:0006351 377 0.074
cellular response to endogenous stimulus GO:0071495 377 0.074
response to molecule of bacterial origin GO:0002237 194 0.063
regulation of rna biosynthetic process GO:2001141 381 0.059
circulatory system development GO:0072359 134 0.056
Human
cellular response to external stimulus GO:0071496 118 0.054
intracellular signal transduction GO:0035556 314 0.053
Human
cellular lipid metabolic process GO:0044255 208 0.053
negative regulation of cellular metabolic process GO:0031324 281 0.052
Human
carboxylic acid biosynthetic process GO:0046394 83 0.051
negative regulation of macromolecule metabolic process GO:0010605 260 0.050
Human
response to wounding GO:0009611 254 0.049
reproductive process GO:0022414 372 0.049
cellular response to stress GO:0033554 269 0.049
Human
negative regulation of phosphorus metabolic process GO:0010563 80 0.049
Human
cellular response to molecule of bacterial origin GO:0071219 56 0.048
organonitrogen compound catabolic process GO:1901565 179 0.048
negative regulation of multicellular organismal process GO:0051241 203 0.047
Human
regulation of smooth muscle cell proliferation GO:0048660 75 0.047
positive regulation of cell proliferation GO:0008284 249 0.047
negative regulation of molecular function GO:0044092 133 0.046
small molecule biosynthetic process GO:0044283 124 0.046
fatty acid derivative metabolic process GO:1901568 38 0.046
regulation of phosphate metabolic process GO:0019220 349 0.044
Human
homeostatic process GO:0042592 331 0.044
liver development GO:0001889 90 0.043
positive regulation of developmental process GO:0051094 283 0.043
macromolecular complex assembly GO:0065003 273 0.043
immune effector process GO:0002252 53 0.043
immune response GO:0006955 104 0.042
regulation of cellular ketone metabolic process GO:0010565 27 0.042
unsaturated fatty acid biosynthetic process GO:0006636 21 0.041
aging GO:0007568 241 0.041
icosanoid biosynthetic process GO:0046456 18 0.040
response to temperature stimulus GO:0009266 94 0.040
b cell mediated immunity GO:0019724 4 0.039
response to estradiol GO:0032355 164 0.039
cellular ketone metabolic process GO:0042180 51 0.039
macromolecular complex subunit organization GO:0043933 339 0.039
positive regulation of cellular biosynthetic process GO:0031328 295 0.038
protein complex biogenesis GO:0070271 263 0.038
peptidyl tyrosine modification GO:0018212 72 0.038
regulation of response to stress GO:0080134 126 0.038
Human
organic cyclic compound catabolic process GO:1901361 175 0.038
negative regulation of signal transduction GO:0009968 83 0.038
Human
negative regulation of signaling GO:0023057 157 0.038
Human
multi organism reproductive process GO:0044703 262 0.037
cell cell signaling GO:0007267 335 0.037
organic acid biosynthetic process GO:0016053 83 0.037
regulation of neurogenesis GO:0050767 247 0.037
response to peptidoglycan GO:0032494 1 0.037
localization of cell GO:0051674 202 0.036
catabolic process GO:0009056 351 0.036
regulation of cellular protein metabolic process GO:0032268 267 0.036
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.035
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
organophosphate metabolic process GO:0019637 370 0.035
regulation of immune system process GO:0002682 123 0.035
regulation of phosphorylation GO:0042325 248 0.034
Human
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
cellular response to biotic stimulus GO:0071216 59 0.034
innate immune response GO:0045087 35 0.034
carbohydrate derivative metabolic process GO:1901135 346 0.033
amine metabolic process GO:0009308 38 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.033
negative regulation of cell death GO:0060548 229 0.033
cognition GO:0050890 92 0.033
protein complex assembly GO:0006461 263 0.032
cellular amino acid metabolic process GO:0006520 107 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
tumor necrosis factor superfamily cytokine production GO:0071706 13 0.031
defense response to gram positive bacterium GO:0050830 2 0.031
protein localization GO:0008104 191 0.031
positive regulation of biosynthetic process GO:0009891 319 0.031
fatty acid biosynthetic process GO:0006633 33 0.031
response to extracellular stimulus GO:0009991 380 0.030
regulation of system process GO:0044057 208 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
smooth muscle cell proliferation GO:0048659 77 0.029
endocytosis GO:0006897 84 0.029
response to peptide GO:1901652 292 0.029
neurological system process GO:0050877 219 0.029
negative regulation of apoptotic process GO:0043066 181 0.029
negative regulation of phosphate metabolic process GO:0045936 80 0.028
Human
response to nutrient GO:0007584 248 0.028
positive regulation of nervous system development GO:0051962 178 0.028
multi multicellular organism process GO:0044706 138 0.028
glycerolipid metabolic process GO:0046486 67 0.028
cellular response to lipopolysaccharide GO:0071222 55 0.028
positive regulation of cell differentiation GO:0045597 217 0.028
cellular amine metabolic process GO:0044106 38 0.028
response to molecule of fungal origin GO:0002238 3 0.028
regulation of cell activation GO:0050865 50 0.028
positive regulation of chemokine production GO:0032722 4 0.027
negative regulation of gene expression GO:0010629 199 0.027
Human
regulation of cellular component organization GO:0051128 368 0.027
negative regulation of programmed cell death GO:0043069 183 0.027
tumor necrosis factor production GO:0032640 13 0.027
chemical homeostasis GO:0048878 292 0.027
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 13 0.026
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 8 0.026
response to nutrient levels GO:0031667 370 0.026
cellular response to reactive oxygen species GO:0034614 55 0.026
response to peptide hormone GO:0043434 278 0.026
positive regulation of apoptotic process GO:0043065 154 0.026
Human
positive regulation of cellular component organization GO:0051130 200 0.026
hepaticobiliary system development GO:0061008 90 0.025
respiratory system development GO:0060541 45 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
cellular catabolic process GO:0044248 295 0.025
protein oligomerization GO:0051259 191 0.024
monocarboxylic acid metabolic process GO:0032787 152 0.024
protein homotrimerization GO:0070207 15 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
Human
response to glucose GO:0009749 136 0.024
lipid catabolic process GO:0016042 46 0.024
positive regulation of gene expression GO:0010628 244 0.024
negative regulation of biosynthetic process GO:0009890 168 0.024
sexual reproduction GO:0019953 148 0.023
regulation of immune response GO:0050776 55 0.023
cellular response to cytokine stimulus GO:0071345 127 0.023
cation homeostasis GO:0055080 195 0.023
negative regulation of cellular biosynthetic process GO:0031327 161 0.023
negative regulation of protein metabolic process GO:0051248 114 0.023
Human
leukocyte mediated immunity GO:0002443 28 0.023
synaptic transmission GO:0007268 235 0.023
cell type specific apoptotic process GO:0097285 134 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
regulation of protein metabolic process GO:0051246 289 0.022
Human
regulation of secretion GO:0051046 224 0.022
single organism catabolic process GO:0044712 283 0.022
regulation of body fluid levels GO:0050878 90 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
cell projection organization GO:0030030 302 0.021
regulation of signal transduction GO:0009966 318 0.021
Human
cellular component biogenesis GO:0044085 368 0.021
single organism carbohydrate metabolic process GO:0044723 118 0.021
inflammatory response GO:0006954 150 0.021
negative regulation of cellular protein metabolic process GO:0032269 106 0.021
Human
cellular response to hormone stimulus GO:0032870 247 0.021
leukotriene biosynthetic process GO:0019370 3 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
muscle cell proliferation GO:0033002 84 0.021
intracellular transport GO:0046907 185 0.021
protein phosphorylation GO:0006468 345 0.020
Human
negative regulation of transport GO:0051051 136 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
Human
coagulation GO:0050817 28 0.020
transmembrane transport GO:0055085 412 0.020
response to transition metal nanoparticle GO:1990267 122 0.020
tube development GO:0035295 89 0.020
regulation of response to wounding GO:1903034 69 0.020
response to carbohydrate GO:0009743 183 0.020
secretion GO:0046903 307 0.019
response to hexose GO:0009746 144 0.019
purine nucleoside metabolic process GO:0042278 169 0.019
positive regulation of cell death GO:0010942 184 0.019
Human
protein complex subunit organization GO:0071822 302 0.019
neuron development GO:0048666 286 0.019
proteolysis GO:0006508 175 0.019
Human
antigen processing and presentation of peptide antigen GO:0048002 2 0.019
cellular response to oxidative stress GO:0034599 76 0.019
antigen processing and presentation GO:0019882 2 0.019
regulation of defense response GO:0031347 68 0.019
purine containing compound biosynthetic process GO:0072522 85 0.018
regulation of cell differentiation GO:0045595 320 0.018
Human
negative regulation of humoral immune response GO:0002921 4 0.018
cell activation GO:0001775 97 0.018
nucleoside metabolic process GO:0009116 179 0.018
regulation of neuron projection development GO:0010975 161 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
regulation of locomotion GO:0040012 148 0.018
positive regulation of molecular function GO:0044093 230 0.018
Human
cellular response to abiotic stimulus GO:0071214 85 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
regulation of proteolysis GO:0030162 66 0.018
Human
cytokine production GO:0001816 61 0.018
regulation of tumor necrosis factor production GO:0032680 13 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
single organism carbohydrate catabolic process GO:0044724 40 0.017
cellular component assembly GO:0022607 360 0.017
regulation of cell development GO:0060284 263 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
positive regulation of transport GO:0051050 245 0.017
single organism cellular localization GO:1902580 102 0.017
steroid metabolic process GO:0008202 73 0.017
regulation of stress activated mapk cascade GO:0032872 23 0.017
Human
chromatin assembly or disassembly GO:0006333 1 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
negative regulation of developmental process GO:0051093 125 0.017
Human
carbohydrate metabolic process GO:0005975 130 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.017
Human
regulation of ion transmembrane transport GO:0034765 121 0.017
regulation of nervous system development GO:0051960 264 0.017
negative regulation of immune system process GO:0002683 39 0.016
cell migration GO:0016477 197 0.016
negative regulation of catalytic activity GO:0043086 103 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
positive regulation of neuron projection development GO:0010976 99 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
Human
neuron projection development GO:0031175 273 0.016
protein transport GO:0015031 132 0.016
lipid storage GO:0019915 1 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
response to calcium ion GO:0051592 59 0.016
regulation of catalytic activity GO:0050790 304 0.016
Human
purine nucleotide metabolic process GO:0006163 229 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
response to cytokine GO:0034097 215 0.016
cellular homeostasis GO:0019725 252 0.016
vesicle mediated transport GO:0016192 181 0.015
dna metabolic process GO:0006259 96 0.015
insulin secretion GO:0030073 69 0.015
blood circulation GO:0008015 183 0.015
nucleotide metabolic process GO:0009117 279 0.015
regulation of response to external stimulus GO:0032101 106 0.015
peptidyl tyrosine phosphorylation GO:0018108 72 0.015
regulation of cell projection organization GO:0031344 175 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
negative regulation of viral process GO:0048525 4 0.015
neutrophil apoptotic process GO:0001781 4 0.015
viral gene expression GO:0019080 2 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
respiratory tube development GO:0030323 43 0.015
central nervous system development GO:0007417 311 0.015
apoptotic process GO:0006915 381 0.015
Human
activation of immune response GO:0002253 26 0.015
mapk cascade GO:0000165 140 0.015
Human
regulation of vasculature development GO:1901342 44 0.015
Human
response to reactive oxygen species GO:0000302 120 0.015
nitrogen compound transport GO:0071705 229 0.014
negative regulation of response to external stimulus GO:0032102 37 0.014
behavior GO:0007610 205 0.014
regulation of molecular function GO:0065009 398 0.014
Human
regulation of programmed cell death GO:0043067 341 0.014
Human
negative regulation of innate immune response GO:0045824 4 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
cellular response to camp GO:0071320 26 0.014
monocarboxylic acid biosynthetic process GO:0072330 48 0.014
neuron differentiation GO:0030182 368 0.014
embryonic pattern specification GO:0009880 1 0.014
regulation of interleukin 6 production GO:0032675 12 0.014
negative regulation of cell communication GO:0010648 158 0.014
Human
vascular process in circulatory system GO:0003018 96 0.014
regulation of leukocyte proliferation GO:0070663 26 0.014
axis specification GO:0009798 4 0.014
positive regulation of programmed cell death GO:0043068 157 0.013
Human
positive regulation of phosphorylation GO:0042327 177 0.013
Human
response to camp GO:0051591 91 0.013
positive regulation of cytokine production GO:0001819 42 0.013
regulation of inflammatory response GO:0050727 48 0.013
lung development GO:0030324 43 0.013
response to toxic substance GO:0009636 133 0.013
regulation of interleukin 8 production GO:0032677 2 0.013
negative regulation of nf kappab transcription factor activity GO:0032088 4 0.013
regulation of dendrite development GO:0050773 59 0.013
blood coagulation GO:0007596 26 0.013
viral genome replication GO:0019079 2 0.013
regulation of mononuclear cell proliferation GO:0032944 26 0.013
metal ion transport GO:0030001 289 0.013
fatty acid derivative biosynthetic process GO:1901570 18 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
circulatory system process GO:0003013 183 0.013
positive regulation of interleukin 6 production GO:0032755 8 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.012
epithelial cell differentiation GO:0030855 71 0.012
Human
positive regulation of hemostasis GO:1900048 4 0.012
regulation of protein modification process GO:0031399 194 0.012
Human
nuclear import GO:0051170 35 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
complement activation GO:0006956 11 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
Human
macromolecule catabolic process GO:0009057 58 0.012
muscle system process GO:0003012 115 0.012
single organism intracellular transport GO:1902582 166 0.012
amp metabolic process GO:0046033 8 0.012
erk1 and erk2 cascade GO:0070371 48 0.012
regulation of blood pressure GO:0008217 83 0.012
peptidyl amino acid modification GO:0018193 126 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
regulation of cytokine biosynthetic process GO:0042035 3 0.012
positive regulation of immune response GO:0050778 42 0.012
positive regulation of cell development GO:0010720 176 0.012
regulation of lymphocyte proliferation GO:0050670 26 0.012
negative regulation of protein modification process GO:0031400 52 0.012
Human
defense response to gram negative bacterium GO:0050829 3 0.011
response to monosaccharide GO:0034284 159 0.011
regulation of multicellular organismal development GO:2000026 376 0.011
Human
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
negative regulation of intracellular signal transduction GO:1902532 38 0.011
Human
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
maintenance of location GO:0051235 17 0.011
negative regulation of homeostatic process GO:0032845 47 0.011
cellular component movement GO:0006928 248 0.011
regulation of transmembrane transport GO:0034762 122 0.011
regulation of neutrophil apoptotic process GO:0033029 4 0.011
activation of cysteine type endopeptidase activity GO:0097202 4 0.011
Human
neuron death GO:0070997 127 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
peptide metabolic process GO:0006518 32 0.011
glucose homeostasis GO:0042593 75 0.011
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 4 0.011
Human
ion transmembrane transport GO:0034220 365 0.011
defense response to other organism GO:0098542 17 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
epithelium development GO:0060429 96 0.011
Human
cellular response to starvation GO:0009267 27 0.011
endothelial cell differentiation GO:0045446 9 0.011
Human
response to starvation GO:0042594 59 0.011
regulation of cell migration GO:0030334 128 0.011
positive regulation of blood coagulation GO:0030194 4 0.011
axon development GO:0061564 96 0.011
glomerular mesangium development GO:0072109 4 0.011
programmed necrotic cell death GO:0097300 2 0.011
cellular chemical homeostasis GO:0055082 247 0.011
chemosensory behavior GO:0007635 2 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
peptide secretion GO:0002790 86 0.011
positive regulation of blood circulation GO:1903524 65 0.011
regulation of blood vessel size GO:0050880 89 0.011
response to oxidative stress GO:0006979 186 0.011
cellular amide metabolic process GO:0043603 44 0.011
regulation of viral transcription GO:0046782 2 0.011
locomotion GO:0040011 237 0.011
gland development GO:0048732 155 0.011
phospholipid metabolic process GO:0006644 61 0.011
protein homooligomerization GO:0051260 91 0.011
purine containing compound catabolic process GO:0072523 138 0.010
regulation of hormone levels GO:0010817 187 0.010
purine containing compound metabolic process GO:0072521 253 0.010
response to mechanical stimulus GO:0009612 134 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
Human
cardiovascular system development GO:0072358 134 0.010
Human
regulation of homeostatic process GO:0032844 101 0.010
negative regulation of secretion GO:0051048 82 0.010
purine nucleoside catabolic process GO:0006152 124 0.010
regulation of immunoglobulin production GO:0002637 4 0.010
establishment of protein localization GO:0045184 141 0.010
regulation of hydrolase activity GO:0051336 143 0.010
Human
regulation of membrane potential GO:0042391 110 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
Human
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.010
brain development GO:0007420 247 0.010
regulation of secretion by cell GO:1903530 208 0.010
cellular response to alcohol GO:0097306 87 0.010

Xdh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.049
cancer DOID:162 0 0.023
organ system cancer DOID:0050686 0 0.023
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011
cardiovascular system disease DOID:1287 0 0.011