Rattus norvegicus

69 known processes

Nr5a1

nuclear receptor subfamily 5, group A, member 1

(Aliases: Ftzf1,Ad4BP/SF-1,Ad4bp,Sf-1)

Nr5a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna biosynthetic process GO:0032774 380 0.388
regulation of nucleic acid templated transcription GO:1903506 380 0.356
regulation of rna biosynthetic process GO:2001141 381 0.280
rna metabolic process GO:0016070 406 0.258
response to extracellular stimulus GO:0009991 380 0.258
regulation of transcription dna templated GO:0006355 374 0.164
nucleic acid templated transcription GO:0097659 379 0.157
central nervous system development GO:0007417 311 0.154
Zebrafish Fly
negative regulation of rna biosynthetic process GO:1902679 118 0.143
regulation of rna metabolic process GO:0051252 391 0.131
small molecule biosynthetic process GO:0044283 124 0.130
anion transport GO:0006820 178 0.125
response to acid chemical GO:0001101 222 0.119
homeostatic process GO:0042592 331 0.114
Fly
regulation of signal transduction GO:0009966 318 0.113
negative regulation of cellular biosynthetic process GO:0031327 161 0.111
response to nutrient levels GO:0031667 370 0.111
negative regulation of nervous system development GO:0051961 79 0.110
cellular component assembly GO:0022607 360 0.104
transcription from rna polymerase ii promoter GO:0006366 252 0.101
cellular amino acid metabolic process GO:0006520 107 0.100
cell morphogenesis GO:0000902 142 0.098
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.095
Human Zebrafish Mouse Fly
negative regulation of cell proliferation GO:0008285 119 0.093
negative regulation of transcription dna templated GO:0045892 116 0.092
head development GO:0060322 247 0.091
Zebrafish Fly
organic acid metabolic process GO:0006082 292 0.089
multicellular organism reproduction GO:0032504 233 0.089
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.088
Human Zebrafish Mouse Rat Fly
cardiac chamber development GO:0003205 1 0.086
response to inorganic substance GO:0010035 377 0.080
intracellular signal transduction GO:0035556 314 0.079
embryonic skeletal system morphogenesis GO:0048704 3 0.074
regulation of multicellular organismal development GO:2000026 376 0.073
Human Mouse
nucleotide biosynthetic process GO:0009165 98 0.070
cell morphogenesis involved in differentiation GO:0000904 119 0.070
Fly
embryonic skeletal system development GO:0048706 3 0.070
nucleobase containing small molecule metabolic process GO:0055086 316 0.069
positive regulation of cell communication GO:0010647 271 0.068
positive regulation of cellular biosynthetic process GO:0031328 295 0.068
Human Zebrafish Mouse Fly
positive regulation of response to stimulus GO:0048584 285 0.067
s shaped body morphogenesis GO:0072050 2 0.067
carbohydrate derivative metabolic process GO:1901135 346 0.065
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.065
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.064
negative regulation of cellular metabolic process GO:0031324 281 0.063
ion homeostasis GO:0050801 212 0.060
comma shaped body morphogenesis GO:0072049 2 0.060
cellular response to lipid GO:0071396 201 0.059
anatomical structure morphogenesis GO:0009653 298 0.059
Fly
negative regulation of biosynthetic process GO:0009890 168 0.058
protein complex assembly GO:0006461 263 0.058
regulation of organelle organization GO:0033043 80 0.057
purine containing compound metabolic process GO:0072521 253 0.057
single organism behavior GO:0044708 130 0.056
Fly
positive regulation of immunoglobulin mediated immune response GO:0002891 2 0.055
response to growth factor GO:0070848 189 0.055
cellular component morphogenesis GO:0032989 155 0.055
Fly
response to oxidative stress GO:0006979 186 0.054
regulation of anion transport GO:0044070 43 0.054
rhythmic process GO:0048511 156 0.053
Mouse
amine metabolic process GO:0009308 38 0.053
regulation of cellular amine metabolic process GO:0033238 8 0.053
cell cycle GO:0007049 101 0.052
cellular response to endogenous stimulus GO:0071495 377 0.052
Fly
positive regulation of biosynthetic process GO:0009891 319 0.052
Human Zebrafish Mouse Fly
glycosyl compound metabolic process GO:1901657 182 0.051
cell projection organization GO:0030030 302 0.050
Fly
positive regulation of rna metabolic process GO:0051254 203 0.050
Human Zebrafish Mouse Fly
response to estrogen GO:0043627 232 0.050
negative regulation of metabolic process GO:0009892 331 0.050
protein complex subunit organization GO:0071822 302 0.049
negative regulation of rna metabolic process GO:0051253 123 0.049
cognition GO:0050890 92 0.049
negative regulation of apoptotic process GO:0043066 181 0.048
oxoacid metabolic process GO:0043436 290 0.047
purine ribonucleotide metabolic process GO:0009150 227 0.047
cellular response to organic cyclic compound GO:0071407 202 0.047
positive regulation of signal transduction GO:0009967 175 0.047
negative regulation of cell differentiation GO:0045596 99 0.047
cardiac ventricle development GO:0003231 1 0.046
cellular response to growth factor stimulus GO:0071363 162 0.046
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.046
negative regulation of phosphorus metabolic process GO:0010563 80 0.045
cellular component biogenesis GO:0044085 368 0.045
single organism reproductive process GO:0044702 297 0.045
behavioral response to ethanol GO:0048149 1 0.045
single organism intracellular transport GO:1902582 166 0.045
kidney morphogenesis GO:0060993 13 0.044
regulation of phosphorus metabolic process GO:0051174 349 0.044
regeneration GO:0031099 163 0.044
tissue development GO:0009888 252 0.044
Mouse
response to retinoic acid GO:0032526 63 0.044
cell type specific apoptotic process GO:0097285 134 0.044
positive regulation of signaling GO:0023056 270 0.044
single organism biosynthetic process GO:0044711 342 0.043
regulation of molecular function GO:0065009 398 0.043
negative regulation of programmed cell death GO:0043069 183 0.043
metanephric comma shaped body morphogenesis GO:0072278 2 0.042
brain development GO:0007420 247 0.042
Zebrafish Fly
multicellular organismal reproductive process GO:0048609 233 0.042
Mouse
negative regulation of gene expression GO:0010629 199 0.042
regulation of phosphate metabolic process GO:0019220 349 0.042
macromolecular complex subunit organization GO:0043933 339 0.042
response to cytokine GO:0034097 215 0.041
cellular response to hormone stimulus GO:0032870 247 0.040
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.039
transcription dna templated GO:0006351 377 0.039
cellular response to oxygen containing compound GO:1901701 386 0.039
cellular amine metabolic process GO:0044106 38 0.038
enzyme linked receptor protein signaling pathway GO:0007167 116 0.037
organic anion transport GO:0015711 132 0.037
response to reactive oxygen species GO:0000302 120 0.037
response to nutrient GO:0007584 248 0.037
negative regulation of neurogenesis GO:0050768 78 0.036
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.036
response to purine containing compound GO:0014074 126 0.036
kidney epithelium development GO:0072073 19 0.036
metanephric s shaped body morphogenesis GO:0072284 2 0.035
nucleotide metabolic process GO:0009117 279 0.035
regulation of cell differentiation GO:0045595 320 0.035
negative regulation of cell death GO:0060548 229 0.034
negative regulation of nucleic acid templated transcription GO:1903507 117 0.034
cation transport GO:0006812 382 0.034
male gonad development GO:0008584 59 0.034
Human Mouse
response to vitamin GO:0033273 131 0.034
positive regulation of phosphate metabolic process GO:0045937 262 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
positive regulation of synaptic transmission GO:0050806 62 0.032
behavior GO:0007610 205 0.032
Fly
response to decreased oxygen levels GO:0036293 237 0.032
purine nucleotide metabolic process GO:0006163 229 0.031
positive regulation of nucleic acid templated transcription GO:1903508 197 0.031
Human Zebrafish Mouse Fly
divalent inorganic cation homeostasis GO:0072507 165 0.031
cell motility GO:0048870 202 0.031
locomotion GO:0040011 237 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
single organism organelle organization GO:1902589 180 0.030
organophosphate metabolic process GO:0019637 370 0.030
peptidyl amino acid modification GO:0018193 126 0.030
developmental process involved in reproduction GO:0003006 159 0.029
negative regulation of signaling GO:0023057 157 0.029
positive regulation of transport GO:0051050 245 0.029
negative regulation of cell development GO:0010721 82 0.029
negative regulation of calcium ion transport into cytosol GO:0010523 4 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.028
cellular homeostasis GO:0019725 252 0.028
neurological system process GO:0050877 219 0.028
cellular ketone metabolic process GO:0042180 51 0.027
programmed cell death GO:0012501 392 0.027
embryonic pattern specification GO:0009880 1 0.027
Fly
carboxylic acid metabolic process GO:0019752 289 0.027
reproduction GO:0000003 245 0.027
Mouse
regulation of neurogenesis GO:0050767 247 0.027
reproductive system development GO:0061458 128 0.027
blood circulation GO:0008015 183 0.027
glial cell differentiation GO:0010001 65 0.027
intracellular transport GO:0046907 185 0.027
negative regulation of developmental process GO:0051093 125 0.026
Mouse
positive regulation of multicellular organismal process GO:0051240 387 0.026
Human Mouse
muscle structure development GO:0061061 87 0.026
response to oxygen levels GO:0070482 265 0.026
heart morphogenesis GO:0003007 3 0.026
positive regulation of secretion GO:0051047 140 0.026
ovulation cycle process GO:0022602 50 0.025
Mouse
male mating behavior GO:0060179 3 0.025
macromolecular complex assembly GO:0065003 273 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.025
Human Zebrafish Mouse Fly
response to camp GO:0051591 91 0.025
ribose phosphate metabolic process GO:0019693 235 0.025
negative regulation of multicellular organismal process GO:0051241 203 0.025
Mouse
gliogenesis GO:0042063 93 0.025
sulfur compound metabolic process GO:0006790 70 0.025
regulation of apoptotic process GO:0042981 335 0.025
signal release GO:0023061 145 0.025
regulation of cellular localization GO:0060341 263 0.025
positive regulation of gene expression GO:0010628 244 0.024
Human Zebrafish Mouse Fly
reproductive process GO:0022414 372 0.024
cellular response to acid chemical GO:0071229 75 0.024
metanephros morphogenesis GO:0003338 6 0.024
positive regulation of molecular function GO:0044093 230 0.024
metanephric glomerulus development GO:0072224 3 0.024
ribonucleotide metabolic process GO:0009259 231 0.024
negative regulation of signal transduction GO:0009968 83 0.023
negative regulation of cell communication GO:0010648 158 0.023
organonitrogen compound biosynthetic process GO:1901566 167 0.023
protein complex biogenesis GO:0070271 263 0.023
neuron differentiation GO:0030182 368 0.023
Fly
embryonic cranial skeleton morphogenesis GO:0048701 2 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
Human Zebrafish Mouse Fly
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
neuron development GO:0048666 286 0.022
Fly
regulation of metal ion transport GO:0010959 118 0.022
negative regulation of metanephros development GO:0072217 2 0.022
organic acid biosynthetic process GO:0016053 83 0.022
response to tumor necrosis factor GO:0034612 56 0.022
epithelial cell differentiation GO:0030855 71 0.022
regulation of protein metabolic process GO:0051246 289 0.022
vesicle mediated transport GO:0016192 181 0.021
regulation of intracellular signal transduction GO:1902531 218 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.021
protein phosphorylation GO:0006468 345 0.021
response to organophosphorus GO:0046683 102 0.021
response to metal ion GO:0010038 253 0.021
cellular catabolic process GO:0044248 295 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
sequestering of metal ion GO:0051238 9 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
craniofacial suture morphogenesis GO:0097094 4 0.020
cellular response to stress GO:0033554 269 0.020
cellular component movement GO:0006928 248 0.020
axis specification GO:0009798 4 0.020
positive regulation of secretion by cell GO:1903532 128 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
Human Zebrafish Mouse Fly
cardiac muscle tissue morphogenesis GO:0055008 1 0.020
cellular ion homeostasis GO:0006873 184 0.019
positive regulation of developmental process GO:0051094 283 0.019
Human Mouse
muscle organ morphogenesis GO:0048644 1 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
cellular macromolecule localization GO:0070727 122 0.019
Mouse
jak stat cascade GO:0007259 26 0.019
organic acid transport GO:0015849 116 0.019
regulation of programmed cell death GO:0043067 341 0.019
response to ethanol GO:0045471 162 0.019
regulation of protein localization GO:0032880 81 0.019
chemical homeostasis GO:0048878 292 0.019
Fly
palate development GO:0060021 2 0.018
response to hydrogen peroxide GO:0042542 89 0.018
antral ovarian follicle growth GO:0001547 3 0.018
response to carbohydrate GO:0009743 183 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
regulation of cell proliferation GO:0042127 359 0.018
sexual reproduction GO:0019953 148 0.018
anterior posterior pattern specification GO:0009952 1 0.018
developmental growth GO:0048589 100 0.018
negative regulation of molecular function GO:0044092 133 0.018
mesonephric tubule development GO:0072164 14 0.018
cell activation GO:0001775 97 0.018
regulation of establishment of protein localization GO:0070201 69 0.018
thyroid gland development GO:0030878 1 0.018
response to estradiol GO:0032355 164 0.018
response to transforming growth factor beta GO:0071559 46 0.018
b cell differentiation GO:0030183 2 0.018
defense response GO:0006952 194 0.018
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.017
cellular protein complex assembly GO:0043623 44 0.017
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 2 0.017
positive regulation of b cell mediated immunity GO:0002714 2 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
mesenchyme development GO:0060485 9 0.017
regulation of muscle system process GO:0090257 79 0.017
nucleoside triphosphate catabolic process GO:0009143 123 0.017
regulation of nervous system development GO:0051960 264 0.017
salivary gland morphogenesis GO:0007435 1 0.016
negative regulation of intracellular estrogen receptor signaling pathway GO:0033147 2 0.016
b cell mediated immunity GO:0019724 4 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
muscle tissue development GO:0060537 58 0.016
regulation of cytoskeleton organization GO:0051493 49 0.016
multi organism reproductive process GO:0044703 262 0.016
carboxylic acid biosynthetic process GO:0046394 83 0.016
regulation of mapk cascade GO:0043408 116 0.016
protein oligomerization GO:0051259 191 0.016
sensory perception of light stimulus GO:0050953 3 0.016
neuron fate commitment GO:0048663 4 0.016
regulation of cell cycle GO:0051726 73 0.016
response to hexose GO:0009746 144 0.016
peptidyl tyrosine phosphorylation GO:0018108 72 0.015
protein transport GO:0015031 132 0.015
localization of cell GO:0051674 202 0.015
immune system process GO:0002376 204 0.015
negative regulation of kidney development GO:0090185 2 0.015
negative regulation of cellular component organization GO:0051129 83 0.015
cellular response to cytokine stimulus GO:0071345 127 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
regulation of cellular component organization GO:0051128 368 0.015
establishment of protein localization to organelle GO:0072594 44 0.015
endocrine system development GO:0035270 30 0.015
Zebrafish Mouse
regulation of catalytic activity GO:0050790 304 0.015
carboxylic acid transport GO:0046942 115 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
epithelium development GO:0060429 96 0.015
organelle organization GO:0006996 266 0.015
regulation of system process GO:0044057 208 0.014
nephron development GO:0072006 22 0.014
carbohydrate metabolic process GO:0005975 130 0.014
erythrocyte differentiation GO:0030218 1 0.014
neuromuscular process GO:0050905 2 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
signal transduction in absence of ligand GO:0038034 5 0.014
regulation of homeostatic process GO:0032844 101 0.014
regulation of kinase activity GO:0043549 117 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
nephron morphogenesis GO:0072028 13 0.014
response to epidermal growth factor GO:0070849 18 0.014
skeletal system morphogenesis GO:0048705 12 0.014
neural crest cell development GO:0014032 2 0.014
regulation of jak stat cascade GO:0046425 21 0.014
cellular chemical homeostasis GO:0055082 247 0.014
positive regulation of cytokine production GO:0001819 42 0.014
negative regulation of skeletal muscle tissue development GO:0048642 3 0.014
muscle tissue morphogenesis GO:0060415 1 0.014
regulation of ion transport GO:0043269 245 0.014
circulatory system process GO:0003013 183 0.014
embryo development GO:0009790 49 0.014
Fly
interleukin 12 production GO:0032615 3 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
positive regulation of organelle organization GO:0010638 48 0.013
response to hypoxia GO:0001666 231 0.013
regulation of calcium ion transport GO:0051924 77 0.013
female sex differentiation GO:0046660 59 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
cell part morphogenesis GO:0032990 123 0.013
Fly
endocytosis GO:0006897 84 0.013
male sex differentiation GO:0046661 64 0.013
Human Mouse
dendrite morphogenesis GO:0048813 43 0.013
Fly
cell migration GO:0016477 197 0.013
chemosensory behavior GO:0007635 2 0.013
Fly
regulation of cellular protein metabolic process GO:0032268 267 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
negative regulation of ion transport GO:0043271 51 0.013
tissue morphogenesis GO:0048729 22 0.013
negative regulation of transport GO:0051051 136 0.013
calcium ion homeostasis GO:0055074 162 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
wound healing GO:0042060 122 0.013
regulation of stem cell differentiation GO:2000736 2 0.013
cellular macromolecular complex assembly GO:0034622 58 0.013
response to ketone GO:1901654 182 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
ribose phosphate biosynthetic process GO:0046390 87 0.013
coenzyme metabolic process GO:0006732 86 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
metanephric part of ureteric bud development GO:0035502 1 0.013
purine containing compound biosynthetic process GO:0072522 85 0.013
secretion by cell GO:0032940 248 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
olfactory behavior GO:0042048 2 0.012
Fly
establishment of protein localization GO:0045184 141 0.012
biological adhesion GO:0022610 110 0.012
skeletal system development GO:0001501 41 0.012
sequestering of calcium ion GO:0051208 8 0.012
response to temperature stimulus GO:0009266 94 0.012
cation transmembrane transport GO:0098655 263 0.012
regulation of intracellular transport GO:0032386 65 0.012
camera type eye development GO:0043010 48 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.012
Human Zebrafish Mouse Fly
neuron projection development GO:0031175 273 0.012
Fly
prepulse inhibition GO:0060134 1 0.012
regulation of cell cycle process GO:0010564 31 0.012
response to toxic substance GO:0009636 133 0.012
dephosphorylation GO:0016311 98 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 35 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
cellular amino acid biosynthetic process GO:0008652 32 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
immunoglobulin mediated immune response GO:0016064 4 0.012
positive regulation of immunoglobulin production GO:0002639 4 0.011
neural crest cell migration GO:0001755 1 0.011
response to peptide hormone GO:0043434 278 0.011
endocardial cushion development GO:0003197 1 0.011
learning or memory GO:0007611 90 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
cell cell signaling GO:0007267 335 0.011
response to glucose GO:0009749 136 0.011
cellular lipid metabolic process GO:0044255 208 0.011
mapk cascade GO:0000165 140 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
cellular response to peptide GO:1901653 133 0.011
muscle organ development GO:0007517 50 0.011
regulation of protein modification process GO:0031399 194 0.011
triglyceride homeostasis GO:0070328 2 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
calcium ion transport GO:0006816 131 0.011
cell differentiation involved in kidney development GO:0061005 4 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
negative regulation of homeostatic process GO:0032845 47 0.011
regulation of exit from mitosis GO:0007096 1 0.011
growth GO:0040007 165 0.011
single organism membrane organization GO:0044802 74 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
organophosphate catabolic process GO:0046434 148 0.011
respiratory system process GO:0003016 3 0.011
phototransduction visible light GO:0007603 2 0.010
negative regulation of protein modification process GO:0031400 52 0.010
leukocyte activation GO:0045321 76 0.010
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.010
signal transduction by phosphorylation GO:0023014 144 0.010
cellular response to reactive oxygen species GO:0034614 55 0.010
g protein coupled receptor signaling pathway GO:0007186 242 0.010
positive regulation of cell differentiation GO:0045597 217 0.010
eye morphogenesis GO:0048592 4 0.010
response to radiation GO:0009314 137 0.010
response to alkaloid GO:0043279 132 0.010
positive regulation of apoptotic process GO:0043065 154 0.010

Nr5a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
Human
musculoskeletal system disease DOID:17 0 0.059
urinary system disease DOID:18 0 0.038
nervous system disease DOID:863 0 0.033
kidney disease DOID:557 0 0.028
muscular disease DOID:0080000 0 0.020
muscle tissue disease DOID:66 0 0.020
connective tissue disease DOID:65 0 0.020
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
endocrine gland cancer DOID:170 0 0.014
organ system cancer DOID:0050686 0 0.014
respiratory system disease DOID:1579 0 0.012
lower respiratory tract disease DOID:0050161 0 0.012
renal tubular transport disease DOID:447 0 0.011
bone disease DOID:0080001 0 0.010