Rattus norvegicus

0 known processes

Osbp2

oxysterol binding protein 2

(Aliases: RGD1309479)

Osbp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 365 0.438
protein complex assembly GO:0006461 263 0.233
cation transport GO:0006812 382 0.221
protein complex subunit organization GO:0071822 302 0.182
transmembrane transport GO:0055085 412 0.159
establishment of organ orientation GO:0048561 1 0.158
protein complex biogenesis GO:0070271 263 0.150
cellular component biogenesis GO:0044085 368 0.149
anatomical structure morphogenesis GO:0009653 298 0.135
macromolecular complex subunit organization GO:0043933 339 0.124
establishment of anatomical structure orientation GO:0048560 1 0.119
neuron differentiation GO:0030182 368 0.117
transcription from rna polymerase ii promoter GO:0006366 252 0.116
cellular response to oxygen containing compound GO:1901701 386 0.111
neuron development GO:0048666 286 0.109
regulation of metal ion transport GO:0010959 118 0.105
divalent metal ion transport GO:0070838 132 0.088
inorganic ion transmembrane transport GO:0098660 229 0.086
metal ion transport GO:0030001 289 0.086
macromolecular complex assembly GO:0065003 273 0.085
inorganic cation transmembrane transport GO:0098662 202 0.080
positive regulation of nucleic acid templated transcription GO:1903508 197 0.079
regulation of molecular function GO:0065009 398 0.077
regulation of cellular component organization GO:0051128 368 0.074
apoptotic process GO:0006915 381 0.070
cellular component assembly GO:0022607 360 0.070
regulation of neuron differentiation GO:0045664 208 0.067
macromolecule localization GO:0033036 252 0.065
response to glucocorticoid GO:0051384 223 0.062
oligopeptide transport GO:0006857 4 0.062
chemical homeostasis GO:0048878 292 0.060
hormone metabolic process GO:0042445 69 0.060
amino acid transport GO:0006865 70 0.060
single organism catabolic process GO:0044712 283 0.059
regulation of ion transport GO:0043269 245 0.058
calcium ion homeostasis GO:0055074 162 0.057
cellular chemical homeostasis GO:0055082 247 0.057
response to acid chemical GO:0001101 222 0.057
regulation of neuron projection development GO:0010975 161 0.057
tissue development GO:0009888 252 0.056
rna biosynthetic process GO:0032774 380 0.054
anion transport GO:0006820 178 0.053
regulation of transcription dna templated GO:0006355 374 0.053
intracellular signal transduction GO:0035556 314 0.052
regulation of multicellular organismal development GO:2000026 376 0.051
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.051
negative regulation of cellular metabolic process GO:0031324 281 0.050
cytosolic calcium ion homeostasis GO:0051480 140 0.050
neuron projection development GO:0031175 273 0.050
response to inorganic substance GO:0010035 377 0.049
negative regulation of metabolic process GO:0009892 331 0.049
regulation of nucleic acid templated transcription GO:1903506 380 0.048
carboxylic acid transport GO:0046942 115 0.048
cation transmembrane transport GO:0098655 263 0.047
homeostatic process GO:0042592 331 0.047
regulation of rna biosynthetic process GO:2001141 381 0.046
negative regulation of cellular biosynthetic process GO:0031327 161 0.045
protein oligomerization GO:0051259 191 0.045
central nervous system development GO:0007417 311 0.044
organic anion transport GO:0015711 132 0.043
intracellular transport GO:0046907 185 0.042
response to corticosteroid GO:0031960 235 0.041
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.041
rna metabolic process GO:0016070 406 0.038
brain development GO:0007420 247 0.038
cellular calcium ion homeostasis GO:0006874 160 0.038
cell motility GO:0048870 202 0.037
cellular amide metabolic process GO:0043603 44 0.037
response to peptide hormone GO:0043434 278 0.037
positive regulation of cellular biosynthetic process GO:0031328 295 0.037
reproductive system development GO:0061458 128 0.037
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.036
regulation of cell development GO:0060284 263 0.036
regulation of neurogenesis GO:0050767 247 0.035
transcription dna templated GO:0006351 377 0.035
development of primary sexual characteristics GO:0045137 107 0.035
cytoskeleton organization GO:0007010 111 0.035
neurological system process GO:0050877 219 0.034
nucleobase containing small molecule metabolic process GO:0055086 316 0.034
response to hexose GO:0009746 144 0.034
dicarboxylic acid transport GO:0006835 34 0.033
cellular response to stress GO:0033554 269 0.032
ion homeostasis GO:0050801 212 0.032
gonad development GO:0008406 104 0.032
sensory perception GO:0007600 101 0.031
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.031
development of primary female sexual characteristics GO:0046545 56 0.031
locomotion GO:0040011 237 0.031
nucleic acid templated transcription GO:0097659 379 0.031
aging GO:0007568 241 0.031
cell morphogenesis GO:0000902 142 0.031
response to carbohydrate GO:0009743 183 0.030
cellular homeostasis GO:0019725 252 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.030
organonitrogen compound catabolic process GO:1901565 179 0.029
response to oxidative stress GO:0006979 186 0.029
axon development GO:0061564 96 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.029
multicellular organismal reproductive process GO:0048609 233 0.029
cell cycle GO:0007049 101 0.029
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.028
cellular divalent inorganic cation homeostasis GO:0072503 162 0.028
organophosphate metabolic process GO:0019637 370 0.028
growth GO:0040007 165 0.027
positive regulation of transcription dna templated GO:0045893 197 0.027
organic hydroxy compound metabolic process GO:1901615 115 0.026
response to external biotic stimulus GO:0043207 221 0.026
negative regulation of transport GO:0051051 136 0.026
lipid metabolic process GO:0006629 283 0.026
response to temperature stimulus GO:0009266 94 0.026
synaptic growth at neuromuscular junction GO:0051124 1 0.026
positive regulation of biosynthetic process GO:0009891 319 0.026
single organism intracellular transport GO:1902582 166 0.026
response to monosaccharide GO:0034284 159 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
organic acid transport GO:0015849 116 0.026
response to reactive oxygen species GO:0000302 120 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.025
cellular component morphogenesis GO:0032989 155 0.025
sex differentiation GO:0007548 113 0.025
cellular catabolic process GO:0044248 295 0.025
reproductive structure development GO:0048608 128 0.025
regulation of cell differentiation GO:0045595 320 0.025
action potential GO:0001508 54 0.024
programmed cell death GO:0012501 392 0.024
ovulation cycle process GO:0022602 50 0.024
protein localization GO:0008104 191 0.024
cation homeostasis GO:0055080 195 0.024
organophosphate biosynthetic process GO:0090407 143 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
metal ion homeostasis GO:0055065 186 0.023
cellular cation homeostasis GO:0030003 180 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
head development GO:0060322 247 0.023
blood circulation GO:0008015 183 0.023
secretion GO:0046903 307 0.023
regulation of intracellular signal transduction GO:1902531 218 0.023
response to mechanical stimulus GO:0009612 134 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
organelle organization GO:0006996 266 0.022
response to transition metal nanoparticle GO:1990267 122 0.022
sodium ion transmembrane transport GO:0035725 67 0.022
cellular metal ion homeostasis GO:0006875 172 0.022
developmental growth GO:0048589 100 0.022
response to glucose GO:0009749 136 0.022
regulation of rna metabolic process GO:0051252 391 0.022
dendrite development GO:0016358 72 0.021
reproduction GO:0000003 245 0.021
regulation of apoptotic process GO:0042981 335 0.021
response to estrogen GO:0043627 232 0.021
eye morphogenesis GO:0048592 4 0.021
response to camp GO:0051591 91 0.020
retina morphogenesis in camera type eye GO:0060042 1 0.020
organic substance catabolic process GO:1901575 316 0.020
negative regulation of developmental process GO:0051093 125 0.020
catabolic process GO:0009056 351 0.020
regulation of cell projection organization GO:0031344 175 0.020
cellular modified amino acid metabolic process GO:0006575 61 0.019
negative regulation of transcription dna templated GO:0045892 116 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
regulation of programmed cell death GO:0043067 341 0.019
vesicle mediated transport GO:0016192 181 0.019
response to extracellular stimulus GO:0009991 380 0.019
mechanoreceptor differentiation GO:0042490 2 0.019
peptide metabolic process GO:0006518 32 0.019
synaptic transmission GO:0007268 235 0.019
calcium ion transport GO:0006816 131 0.019
cytoplasmic transport GO:0016482 115 0.019
regulation of phosphate metabolic process GO:0019220 349 0.018
cell migration GO:0016477 197 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
female gonad development GO:0008585 53 0.018
negative regulation of rna biosynthetic process GO:1902679 118 0.018
response to growth factor GO:0070848 189 0.018
embryo development GO:0009790 49 0.018
protein phosphorylation GO:0006468 345 0.018
negative regulation of ion transport GO:0043271 51 0.018
response to retinoic acid GO:0032526 63 0.018
response to ammonium ion GO:0060359 71 0.017
response to ethanol GO:0045471 162 0.017
regulation of system process GO:0044057 208 0.017
divalent inorganic cation transport GO:0072511 134 0.017
developmental process involved in reproduction GO:0003006 159 0.017
cellular component movement GO:0006928 248 0.017
response to metal ion GO:0010038 253 0.017
response to ketone GO:1901654 182 0.017
regulation of nervous system development GO:0051960 264 0.017
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.017
cell adhesion GO:0007155 110 0.016
response to hydrogen peroxide GO:0042542 89 0.016
response to organophosphorus GO:0046683 102 0.016
regulation of phosphorylation GO:0042325 248 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
regulation of hormone levels GO:0010817 187 0.016
actin filament based process GO:0030029 86 0.015
sulfur compound metabolic process GO:0006790 70 0.015
response to alkaloid GO:0043279 132 0.015
regulation of cellular component biogenesis GO:0044087 86 0.015
cellular ion homeostasis GO:0006873 184 0.015
palate development GO:0060021 2 0.015
secretion by cell GO:0032940 248 0.015
establishment of tissue polarity GO:0007164 2 0.015
positive regulation of cell development GO:0010720 176 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
micturition GO:0060073 4 0.015
regulation of developmental growth GO:0048638 45 0.015
monocarboxylic acid transport GO:0015718 52 0.015
negative regulation of cell communication GO:0010648 158 0.015
purine containing compound biosynthetic process GO:0072522 85 0.015
membrane depolarization during cardiac muscle cell action potential GO:0086012 1 0.015
phospholipid metabolic process GO:0006644 61 0.015
multicellular organism reproduction GO:0032504 233 0.015
lipid transport GO:0006869 61 0.015
regulation of membrane potential GO:0042391 110 0.015
striated muscle tissue development GO:0014706 58 0.015
rhythmic process GO:0048511 156 0.015
cellular amine metabolic process GO:0044106 38 0.014
ribose phosphate biosynthetic process GO:0046390 87 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
organic acid metabolic process GO:0006082 292 0.014
cell cell signaling involved in cell fate commitment GO:0045168 2 0.014
forebrain development GO:0030900 98 0.014
biological adhesion GO:0022610 110 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
heart development GO:0007507 72 0.014
muscle tissue development GO:0060537 58 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
single organism organelle organization GO:1902589 180 0.014
defense response GO:0006952 194 0.013
response to decreased oxygen levels GO:0036293 237 0.013
positive regulation of gene expression GO:0010628 244 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
muscle structure development GO:0061061 87 0.013
regulation of signal transduction GO:0009966 318 0.013
regulation of hydrolase activity GO:0051336 143 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
camera type eye morphogenesis GO:0048593 2 0.013
protein homooligomerization GO:0051260 91 0.013
male gonad development GO:0008584 59 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
regulation of locomotion GO:0040012 148 0.013
establishment of protein localization GO:0045184 141 0.013
hormone transport GO:0009914 121 0.013
cellular response to ketone GO:1901655 51 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
sensory perception of bitter taste GO:0050913 4 0.012
cell projection organization GO:0030030 302 0.012
anion transmembrane transport GO:0098656 77 0.012
cellular response to histamine GO:0071420 3 0.012
negative regulation of molecular function GO:0044092 133 0.012
cell cycle checkpoint GO:0000075 2 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
inflammatory response GO:0006954 150 0.012
purine containing compound metabolic process GO:0072521 253 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
positive regulation of locomotion GO:0040017 102 0.012
localization of cell GO:0051674 202 0.012
calcium ion transport into cytosol GO:0060402 38 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
positive regulation of molecular function GO:0044093 230 0.012
response to other organism GO:0051707 220 0.012
reproductive process GO:0022414 372 0.012
female sex differentiation GO:0046660 59 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
negative regulation of gene expression GO:0010629 199 0.012
multi organism reproductive process GO:0044703 262 0.012
amine metabolic process GO:0009308 38 0.012
negative regulation of nervous system development GO:0051961 79 0.012
single organism biosynthetic process GO:0044711 342 0.012
nucleotide metabolic process GO:0009117 279 0.011
cyclic purine nucleotide metabolic process GO:0052652 62 0.011
response to lipopolysaccharide GO:0032496 191 0.011
locomotor rhythm GO:0045475 1 0.011
cellular response to oxidative stress GO:0034599 76 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
positive regulation of developmental process GO:0051094 283 0.011
regulation of transmembrane transport GO:0034762 122 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
organic hydroxy compound transport GO:0015850 77 0.011
response to nutrient levels GO:0031667 370 0.011
peptide transport GO:0015833 97 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
positive regulation of nervous system development GO:0051962 178 0.011
regulation of growth GO:0040008 105 0.011
muscle system process GO:0003012 115 0.011
multicellular organism growth GO:0035264 1 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
axis specification GO:0009798 4 0.011
maintenance of location GO:0051235 17 0.011
negative regulation of cell development GO:0010721 82 0.011
regulation of calcineurin nfat signaling cascade GO:0070884 3 0.011
organ morphogenesis GO:0009887 75 0.011
inner ear receptor cell differentiation GO:0060113 2 0.011
regeneration GO:0031099 163 0.011
sequestering of metal ion GO:0051238 9 0.011
regulation of homeostatic process GO:0032844 101 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
amide transport GO:0042886 105 0.011
regulation of vesicle mediated transport GO:0060627 81 0.010
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
regulation of transporter activity GO:0032409 50 0.010
brain renin angiotensin system GO:0002035 3 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
positive regulation of phosphate metabolic process GO:0045937 262 0.010
cellular macromolecule localization GO:0070727 122 0.010
dna integrity checkpoint GO:0031570 2 0.010
neuronal ion channel clustering GO:0045161 3 0.010
response to peptide GO:1901652 292 0.010
cellular hormone metabolic process GO:0034754 49 0.010
heart morphogenesis GO:0003007 3 0.010
positive regulation of epithelial cell proliferation GO:0050679 32 0.010
cellular response to abiotic stimulus GO:0071214 85 0.010
regulation of cellular localization GO:0060341 263 0.010
response to oxygen levels GO:0070482 265 0.010
lipid localization GO:0010876 62 0.010
negative regulation of signaling GO:0023057 157 0.010
renal system development GO:0072001 67 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010

Osbp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.149
disease of anatomical entity DOID:7 0 0.149
nervous system disease DOID:863 0 0.149
eye and adnexa disease DOID:1492 0 0.042
eye disease DOID:5614 0 0.042
retinal disease DOID:5679 0 0.038
retinal degeneration DOID:8466 0 0.038
retinitis pigmentosa DOID:10584 0 0.038
usher syndrome DOID:0050439 0 0.011
muscular disease DOID:0080000 0 0.010
musculoskeletal system disease DOID:17 0 0.010
muscle tissue disease DOID:66 0 0.010