Rattus norvegicus

0 known processes

Sh3tc2

SH3 domain and tetratricopeptide repeats 2

(Aliases: RGD1309038)

Sh3tc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to peptide GO:1901652 292 0.114
response to nutrient levels GO:0031667 370 0.104
response to extracellular stimulus GO:0009991 380 0.096
response to inorganic substance GO:0010035 377 0.089
response to oxygen levels GO:0070482 265 0.085
cellular response to peptide hormone stimulus GO:0071375 120 0.081
apoptotic process GO:0006915 381 0.077
reproductive process GO:0022414 372 0.068
cellular response to lipid GO:0071396 201 0.068
response to peptide hormone GO:0043434 278 0.067
cellular response to hormone stimulus GO:0032870 247 0.066
tissue development GO:0009888 252 0.064
carboxylic acid metabolic process GO:0019752 289 0.059
positive regulation of catalytic activity GO:0043085 184 0.059
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.054
regulation of phosphorus metabolic process GO:0051174 349 0.052
regulation of cellular protein metabolic process GO:0032268 267 0.052
regulation of system process GO:0044057 208 0.052
response to corticosteroid GO:0031960 235 0.050
cellular response to oxygen containing compound GO:1901701 386 0.049
cell motility GO:0048870 202 0.048
organic acid metabolic process GO:0006082 292 0.048
regulation of phosphate metabolic process GO:0019220 349 0.047
positive regulation of biosynthetic process GO:0009891 319 0.043
regulation of apoptotic process GO:0042981 335 0.043
regulation of protein metabolic process GO:0051246 289 0.043
proteolysis GO:0006508 175 0.042
growth GO:0040007 165 0.042
biological adhesion GO:0022610 110 0.040
regulation of blood pressure GO:0008217 83 0.040
regulation of transcription dna templated GO:0006355 374 0.040
neurological system process GO:0050877 219 0.039
cellular response to peptide GO:1901653 133 0.039
regulation of catalytic activity GO:0050790 304 0.039
positive regulation of cellular biosynthetic process GO:0031328 295 0.039
cellular response to external stimulus GO:0071496 118 0.038
cellular response to organonitrogen compound GO:0071417 197 0.038
response to decreased oxygen levels GO:0036293 237 0.037
regulation of molecular function GO:0065009 398 0.037
intracellular signal transduction GO:0035556 314 0.037
oxoacid metabolic process GO:0043436 290 0.037
cellular catabolic process GO:0044248 295 0.036
regulation of signal transduction GO:0009966 318 0.036
regulation of cellular component organization GO:0051128 368 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.036
positive regulation of molecular function GO:0044093 230 0.036
multicellular organismal reproductive process GO:0048609 233 0.035
chemical homeostasis GO:0048878 292 0.035
regulation of cell migration GO:0030334 128 0.035
macromolecular complex subunit organization GO:0043933 339 0.035
single organism reproductive process GO:0044702 297 0.034
regulation of multicellular organismal development GO:2000026 376 0.034
positive regulation of cellular protein metabolic process GO:0032270 167 0.034
single organism biosynthetic process GO:0044711 342 0.034
response to hypoxia GO:0001666 231 0.033
response to glucocorticoid GO:0051384 223 0.033
neuron death GO:0070997 127 0.033
response to starvation GO:0042594 59 0.033
regulation of nucleic acid templated transcription GO:1903506 380 0.033
regulation of rna biosynthetic process GO:2001141 381 0.033
catabolic process GO:0009056 351 0.032
cellular component movement GO:0006928 248 0.031
lipid biosynthetic process GO:0008610 128 0.031
protein phosphorylation GO:0006468 345 0.031
cellular component assembly GO:0022607 360 0.031
macromolecule localization GO:0033036 252 0.030
muscle system process GO:0003012 115 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.030
cellular response to stress GO:0033554 269 0.030
positive regulation of protein metabolic process GO:0051247 178 0.030
regulation of phosphorylation GO:0042325 248 0.029
response to hydrogen peroxide GO:0042542 89 0.029
negative regulation of cell death GO:0060548 229 0.029
rna biosynthetic process GO:0032774 380 0.028
circulatory system process GO:0003013 183 0.028
multi multicellular organism process GO:0044706 138 0.028
rna metabolic process GO:0016070 406 0.028
cellular response to nitrogen compound GO:1901699 210 0.028
negative regulation of metabolic process GO:0009892 331 0.028
cell projection organization GO:0030030 302 0.027
regulation of mesenchymal cell proliferation GO:0010464 4 0.027
regulation of rna metabolic process GO:0051252 391 0.027
response to oxidative stress GO:0006979 186 0.027
regulation of protein modification process GO:0031399 194 0.026
programmed cell death GO:0012501 392 0.026
reproductive structure development GO:0048608 128 0.026
intracellular transport GO:0046907 185 0.026
response to acid chemical GO:0001101 222 0.026
multicellular organismal signaling GO:0035637 44 0.026
negative regulation of response to stimulus GO:0048585 155 0.026
multi organism reproductive process GO:0044703 262 0.026
regulation of canonical wnt signaling pathway GO:0060828 4 0.025
cellular homeostasis GO:0019725 252 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
lipid metabolic process GO:0006629 283 0.025
female pregnancy GO:0007565 122 0.025
response to transition metal nanoparticle GO:1990267 122 0.025
cellular response to endogenous stimulus GO:0071495 377 0.024
response to metal ion GO:0010038 253 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
sexual reproduction GO:0019953 148 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
regulation of protein phosphorylation GO:0001932 183 0.023
response to external biotic stimulus GO:0043207 221 0.023
single organism catabolic process GO:0044712 283 0.022
regulation of cell proliferation GO:0042127 359 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.022
positive regulation of developmental process GO:0051094 283 0.022
gland development GO:0048732 155 0.022
cellular response to abiotic stimulus GO:0071214 85 0.022
cellular response to organic cyclic compound GO:0071407 202 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
cellular ion homeostasis GO:0006873 184 0.021
single organism intracellular transport GO:1902582 166 0.021
cellular component biogenesis GO:0044085 368 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
cell type specific apoptotic process GO:0097285 134 0.021
actin filament based process GO:0030029 86 0.021
protein oligomerization GO:0051259 191 0.021
monocarboxylic acid metabolic process GO:0032787 152 0.021
response to estradiol GO:0032355 164 0.020
cation homeostasis GO:0055080 195 0.020
negative regulation of cell communication GO:0010648 158 0.020
reactive oxygen species metabolic process GO:0072593 37 0.020
positive regulation of gene expression GO:0010628 244 0.020
cell cell signaling GO:0007267 335 0.020
regulation of growth GO:0040008 105 0.020
divalent inorganic cation homeostasis GO:0072507 165 0.020
regulation of cell differentiation GO:0045595 320 0.020
response to insulin GO:0032868 133 0.020
regulation of neuron death GO:1901214 115 0.019
single organism organelle organization GO:1902589 180 0.019
response to nutrient GO:0007584 248 0.019
regulation of cellular catabolic process GO:0031329 101 0.019
response to carbohydrate GO:0009743 183 0.019
cellular chemical homeostasis GO:0055082 247 0.019
nucleic acid templated transcription GO:0097659 379 0.019
cellular cation homeostasis GO:0030003 180 0.019
organic substance catabolic process GO:1901575 316 0.019
negative regulation of signaling GO:0023057 157 0.019
organelle organization GO:0006996 266 0.019
regulation of anatomical structure size GO:0090066 135 0.019
salivary gland development GO:0007431 3 0.018
regulation of transferase activity GO:0051338 123 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
neuron apoptotic process GO:0051402 88 0.018
protein complex assembly GO:0006461 263 0.018
transmission of nerve impulse GO:0019226 42 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
protein complex subunit organization GO:0071822 302 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
male sex differentiation GO:0046661 64 0.018
negative regulation of protein metabolic process GO:0051248 114 0.018
cell adhesion GO:0007155 110 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
organ morphogenesis GO:0009887 75 0.018
regulation of hydrolase activity GO:0051336 143 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
regulation of mapk cascade GO:0043408 116 0.017
regulation of cell motility GO:2000145 131 0.017
metal ion homeostasis GO:0055065 186 0.017
mesenchymal cell proliferation GO:0010463 4 0.017
cell growth GO:0016049 104 0.017
response to testosterone GO:0033574 55 0.017
regulation of body fluid levels GO:0050878 90 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
organophosphate metabolic process GO:0019637 370 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.017
negative regulation of phosphate metabolic process GO:0045936 80 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
regulation of kinase activity GO:0043549 117 0.016
cell migration GO:0016477 197 0.016
protein complex biogenesis GO:0070271 263 0.016
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
regulation of cell growth GO:0001558 85 0.016
macromolecular complex assembly GO:0065003 273 0.015
response to ketone GO:1901654 182 0.015
cellular ketone metabolic process GO:0042180 51 0.015
reproduction GO:0000003 245 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
response to cytokine GO:0034097 215 0.015
regulation of immune system process GO:0002682 123 0.015
negative regulation of osteoblast differentiation GO:0045668 2 0.015
axis specification GO:0009798 4 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
nucleotide metabolic process GO:0009117 279 0.015
homeostatic process GO:0042592 331 0.015
cellular response to mechanical stimulus GO:0071260 48 0.015
multicellular organism reproduction GO:0032504 233 0.015
negative regulation of gene expression GO:0010629 199 0.014
non canonical wnt signaling pathway GO:0035567 3 0.014
positive regulation of protein kinase activity GO:0045860 73 0.014
action potential GO:0001508 54 0.014
epiboly GO:0090504 2 0.014
male gonad development GO:0008584 59 0.014
nitrogen compound transport GO:0071705 229 0.014
synaptic transmission GO:0007268 235 0.014
positive regulation of cell death GO:0010942 184 0.014
head development GO:0060322 247 0.014
response to vitamin GO:0033273 131 0.014
positive regulation of signaling GO:0023056 270 0.014
positive regulation of kinase activity GO:0033674 77 0.014
regulation of neurogenesis GO:0050767 247 0.014
sex differentiation GO:0007548 113 0.014
neuron development GO:0048666 286 0.014
gonad development GO:0008406 104 0.014
central nervous system development GO:0007417 311 0.014
cellular component morphogenesis GO:0032989 155 0.014
response to purine containing compound GO:0014074 126 0.014
embryonic pattern specification GO:0009880 1 0.014
regulation of cytokine production GO:0001817 56 0.014
immune response GO:0006955 104 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
purine containing compound metabolic process GO:0072521 253 0.014
secretion GO:0046903 307 0.014
aging GO:0007568 241 0.013
response to toxic substance GO:0009636 133 0.013
multicellular organism growth GO:0035264 1 0.013
protein processing GO:0016485 68 0.013
brain development GO:0007420 247 0.013
protein localization GO:0008104 191 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
response to biotic stimulus GO:0009607 226 0.013
heterocycle catabolic process GO:0046700 167 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
neuron projection development GO:0031175 273 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
response to reactive oxygen species GO:0000302 120 0.013
cellular amide metabolic process GO:0043603 44 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
cellular lipid metabolic process GO:0044255 208 0.013
regulation of cellular component movement GO:0051270 150 0.013
blood circulation GO:0008015 183 0.013
positive regulation of protein modification process GO:0031401 142 0.013
neuron differentiation GO:0030182 368 0.013
sequestering of metal ion GO:0051238 9 0.012
regulation of protein kinase activity GO:0045859 105 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
wnt signaling pathway GO:0016055 17 0.012
regulation of locomotion GO:0040012 148 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
cellular macromolecule localization GO:0070727 122 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
liver development GO:0001889 90 0.012
response to estrogen GO:0043627 232 0.012
glomerular epithelial cell differentiation GO:0072311 2 0.012
cellular response to alcohol GO:0097306 87 0.012
cellular protein localization GO:0034613 122 0.012
regulation of membrane potential GO:0042391 110 0.012
negative regulation of signal transduction GO:0009968 83 0.012
autonomic nervous system development GO:0048483 3 0.012
ras protein signal transduction GO:0007265 29 0.012
positive regulation of growth GO:0045927 55 0.012
defense response GO:0006952 194 0.012
cellular response to acid chemical GO:0071229 75 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
localization of cell GO:0051674 202 0.012
nucleoside metabolic process GO:0009116 179 0.012
response to mechanical stimulus GO:0009612 134 0.012
regulation of nervous system development GO:0051960 264 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
reproductive system development GO:0061458 128 0.012
regulation of programmed cell death GO:0043067 341 0.012
cellular response to glucocorticoid stimulus GO:0071385 68 0.012
inflammatory response GO:0006954 150 0.011
spermatogenesis GO:0007283 99 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
developmental growth GO:0048589 100 0.011
positive regulation of transferase activity GO:0051347 81 0.011
response to lipopolysaccharide GO:0032496 191 0.011
aromatic compound catabolic process GO:0019439 168 0.011
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.011
regulation of cellular localization GO:0060341 263 0.011
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.011
cell cycle checkpoint GO:0000075 2 0.011
cellular amine metabolic process GO:0044106 38 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
hepaticobiliary system development GO:0061008 90 0.011
regulation of response to stress GO:0080134 126 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
response to organophosphorus GO:0046683 102 0.011
regulation of protein serine threonine kinase activity GO:0071900 64 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
neuronal action potential GO:0019228 35 0.011
locomotion GO:0040011 237 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
circadian rhythm GO:0007623 88 0.011
epithelial cell differentiation GO:0030855 71 0.011
regulation of cell projection organization GO:0031344 175 0.011
protein dephosphorylation GO:0006470 38 0.011
kidney development GO:0001822 67 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
cytoplasmic transport GO:0016482 115 0.011
urogenital system development GO:0001655 78 0.011
renal system process GO:0003014 40 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
regulation of homeostatic process GO:0032844 101 0.010
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
cellular response to steroid hormone stimulus GO:0071383 93 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
nucleotide catabolic process GO:0009166 139 0.010
transcription dna templated GO:0006351 377 0.010
regulation of proteolysis GO:0030162 66 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
positive regulation of rna metabolic process GO:0051254 203 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.010
secretion by cell GO:0032940 248 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
development of primary male sexual characteristics GO:0046546 59 0.010
negative regulation of phosphorylation GO:0042326 57 0.010
regulation of cell development GO:0060284 263 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
positive regulation of locomotion GO:0040017 102 0.010
regulation of ion homeostasis GO:2000021 63 0.010
response to growth factor GO:0070848 189 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010

Sh3tc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
Human
nervous system disease DOID:863 0 0.031
Human
musculoskeletal system disease DOID:17 0 0.028
kidney disease DOID:557 0 0.025
urinary system disease DOID:18 0 0.025
cardiovascular system disease DOID:1287 0 0.020
sensory system disease DOID:0050155 0 0.017
bone disease DOID:0080001 0 0.014
connective tissue disease DOID:65 0 0.014
disease of metabolism DOID:0014667 0 0.012
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.010