Rattus norvegicus

7 known processes

Npepps

aminopeptidase puromycin sensitive

(Aliases: Psa)

Npepps biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic substance catabolic process GO:1901575 316 0.072
Yeast Rat
rna metabolic process GO:0016070 406 0.068
catabolic process GO:0009056 351 0.057
Yeast Rat
vesicle mediated transport GO:0016192 181 0.054
cellular response to oxygen containing compound GO:1901701 386 0.052
anatomical structure morphogenesis GO:0009653 298 0.050
regulation of multicellular organismal development GO:2000026 376 0.046
protein complex biogenesis GO:0070271 263 0.046
neurological system process GO:0050877 219 0.046
macromolecular complex assembly GO:0065003 273 0.045
nitrogen compound transport GO:0071705 229 0.044
regulation of protein metabolic process GO:0051246 289 0.042
negative regulation of metabolic process GO:0009892 331 0.041
regulation of rna biosynthetic process GO:2001141 381 0.041
rna biosynthetic process GO:0032774 380 0.041
nucleic acid templated transcription GO:0097659 379 0.040
protein complex assembly GO:0006461 263 0.040
cellular component biogenesis GO:0044085 368 0.040
oxoacid metabolic process GO:0043436 290 0.038
macromolecule localization GO:0033036 252 0.038
single organism intracellular transport GO:1902582 166 0.038
behavior GO:0007610 205 0.037
regulation of molecular function GO:0065009 398 0.037
carboxylic acid metabolic process GO:0019752 289 0.037
regulation of cell differentiation GO:0045595 320 0.036
cellular component assembly GO:0022607 360 0.036
protein oligomerization GO:0051259 191 0.036
neuron differentiation GO:0030182 368 0.036
regulation of cellular component organization GO:0051128 368 0.034
transcription dna templated GO:0006351 377 0.034
single organism biosynthetic process GO:0044711 342 0.033
establishment of protein localization GO:0045184 141 0.032
negative regulation of cellular metabolic process GO:0031324 281 0.032
central nervous system development GO:0007417 311 0.032
regulation of nervous system development GO:0051960 264 0.031
regulation of apoptotic process GO:0042981 335 0.031
homeostatic process GO:0042592 331 0.031
Rat
regulation of transcription dna templated GO:0006355 374 0.030
programmed cell death GO:0012501 392 0.030
intracellular transport GO:0046907 185 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
regulation of cellular localization GO:0060341 263 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
nucleotide metabolic process GO:0009117 279 0.029
endocytosis GO:0006897 84 0.029
chemical homeostasis GO:0048878 292 0.029
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.029
response to peptide GO:1901652 292 0.028
protein phosphorylation GO:0006468 345 0.028
organophosphate metabolic process GO:0019637 370 0.028
regulation of rna metabolic process GO:0051252 391 0.028
response to nutrient levels GO:0031667 370 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
cellular catabolic process GO:0044248 295 0.027
Yeast Rat
organic acid metabolic process GO:0006082 292 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
response to extracellular stimulus GO:0009991 380 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
single organism catabolic process GO:0044712 283 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
single organism cellular localization GO:1902580 102 0.024
proteolysis GO:0006508 175 0.024
regulation of catalytic activity GO:0050790 304 0.024
developmental growth GO:0048589 100 0.024
cellular protein localization GO:0034613 122 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
protein localization GO:0008104 191 0.024
cell cell signaling GO:0007267 335 0.024
Rat
growth GO:0040007 165 0.023
protein complex subunit organization GO:0071822 302 0.023
positive regulation of developmental process GO:0051094 283 0.023
response to nutrient GO:0007584 248 0.023
secretion GO:0046903 307 0.023
Rat
regulation of neurogenesis GO:0050767 247 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
secretion by cell GO:0032940 248 0.022
regulation of cell development GO:0060284 263 0.022
apoptotic process GO:0006915 381 0.022
tissue development GO:0009888 252 0.022
reproductive process GO:0022414 372 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
regulation of programmed cell death GO:0043067 341 0.022
purine containing compound metabolic process GO:0072521 253 0.022
positive regulation of transport GO:0051050 245 0.021
cellular amine metabolic process GO:0044106 38 0.021
response to wounding GO:0009611 254 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
negative regulation of gene expression GO:0010629 199 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
brain development GO:0007420 247 0.020
oxidation reduction process GO:0055114 304 0.020
Yeast
cognition GO:0050890 92 0.020
head development GO:0060322 247 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
cellular chemical homeostasis GO:0055082 247 0.020
single organism reproductive process GO:0044702 297 0.020
positive regulation of gene expression GO:0010628 244 0.020
single organism behavior GO:0044708 130 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
cellular component movement GO:0006928 248 0.020
response to peptide hormone GO:0043434 278 0.020
transmembrane transport GO:0055085 412 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
spindle organization GO:0007051 2 0.019
response to oxygen levels GO:0070482 265 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
neuron development GO:0048666 286 0.019
positive regulation of signaling GO:0023056 270 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
mitotic spindle organization GO:0007052 2 0.019
cation transport GO:0006812 382 0.019
cell projection morphogenesis GO:0048858 123 0.018
cellular ketone metabolic process GO:0042180 51 0.018
regulation of system process GO:0044057 208 0.018
Rat
response to inorganic substance GO:0010035 377 0.018
neuron projection development GO:0031175 273 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
regulation of secretion GO:0051046 224 0.018
Rat
learning or memory GO:0007611 90 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
response to cytokine GO:0034097 215 0.018
amine metabolic process GO:0009308 38 0.018
regulation of phosphorylation GO:0042325 248 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
cellular macromolecule localization GO:0070727 122 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
synaptic growth at neuromuscular junction GO:0051124 1 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.017
protein transport GO:0015031 132 0.017
metal ion transport GO:0030001 289 0.017
cytoplasmic transport GO:0016482 115 0.017
response to estradiol GO:0032355 164 0.017
organelle organization GO:0006996 266 0.017
response to metal ion GO:0010038 253 0.017
cellular response to stress GO:0033554 269 0.017
multicellular organism reproduction GO:0032504 233 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
cellular homeostasis GO:0019725 252 0.017
regulation of cell growth GO:0001558 85 0.017
response to carbohydrate GO:0009743 183 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
Yeast Rat
response to acid chemical GO:0001101 222 0.016
anatomical structure formation involved in morphogenesis GO:0048646 83 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
response to monosaccharide GO:0034284 159 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
response to glucose GO:0009749 136 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
response to estrogen GO:0043627 232 0.015
gastrulation GO:0007369 2 0.015
cellular component morphogenesis GO:0032989 155 0.015
regeneration GO:0031099 163 0.015
negative regulation of cell development GO:0010721 82 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
Rat
gland development GO:0048732 155 0.015
regulation of phosphate metabolic process GO:0019220 349 0.015
alpha amino acid metabolic process GO:1901605 71 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
regulation of neuron projection development GO:0010975 161 0.015
ras protein signal transduction GO:0007265 29 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
regulation of hormone levels GO:0010817 187 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
aging GO:0007568 241 0.015
regulation of ion transport GO:0043269 245 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
regulation of growth GO:0040008 105 0.015
monocarboxylic acid metabolic process GO:0032787 152 0.015
cell projection organization GO:0030030 302 0.014
heterocycle catabolic process GO:0046700 167 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
reproduction GO:0000003 245 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
circulatory system process GO:0003013 183 0.014
Rat
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
negative regulation of cell communication GO:0010648 158 0.014
negative regulation of cell death GO:0060548 229 0.014
ion homeostasis GO:0050801 212 0.014
Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.014
response to hypoxia GO:0001666 231 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
regulation of cell projection organization GO:0031344 175 0.014
positive regulation of molecular function GO:0044093 230 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
regulation of hydrolase activity GO:0051336 143 0.014
regulation of cell proliferation GO:0042127 359 0.014
anion transport GO:0006820 178 0.014
regulation of catabolic process GO:0009894 113 0.014
negative regulation of programmed cell death GO:0043069 183 0.013
small molecule biosynthetic process GO:0044283 124 0.013
action potential GO:0001508 54 0.013
anterior posterior pattern specification GO:0009952 1 0.013
regulation of membrane potential GO:0042391 110 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
positive regulation of cell development GO:0010720 176 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
response to hexose GO:0009746 144 0.013
intracellular signal transduction GO:0035556 314 0.013
negative regulation of developmental process GO:0051093 125 0.013
metal ion homeostasis GO:0055065 186 0.013
Rat
locomotion GO:0040011 237 0.013
negative regulation of nervous system development GO:0051961 79 0.013
immune system process GO:0002376 204 0.013
response to insulin GO:0032868 133 0.013
negative regulation of transport GO:0051051 136 0.013
Rat
signal release GO:0023061 145 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
response to decreased oxygen levels GO:0036293 237 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
amide transport GO:0042886 105 0.013
multicellular organismal signaling GO:0035637 44 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
positive regulation of signal transduction GO:0009967 175 0.012
positive regulation of cell communication GO:0010647 271 0.012
chromosome segregation GO:0007059 2 0.012
lipid metabolic process GO:0006629 283 0.012
organelle localization GO:0051640 55 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
synaptic transmission GO:0007268 235 0.012
Rat
developmental process involved in reproduction GO:0003006 159 0.012
circulatory system development GO:0072359 134 0.012
cellular lipid metabolic process GO:0044255 208 0.012
membrane depolarization during action potential GO:0086010 1 0.012
negative regulation of signaling GO:0023057 157 0.012
intracellular protein transport GO:0006886 79 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
blood vessel development GO:0001568 69 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
axon development GO:0061564 96 0.012
embryonic pattern specification GO:0009880 1 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
cation homeostasis GO:0055080 195 0.012
Rat
cellular response to hormone stimulus GO:0032870 247 0.012
lipid biosynthetic process GO:0008610 128 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
neuron death GO:0070997 127 0.012
nucleoside metabolic process GO:0009116 179 0.012
glycogen metabolic process GO:0005977 23 0.012
Yeast
cellular response to external stimulus GO:0071496 118 0.012
regulation of neuron differentiation GO:0045664 208 0.012
cell part morphogenesis GO:0032990 123 0.011
axis specification GO:0009798 4 0.011
positive regulation of cell death GO:0010942 184 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
positive regulation of nervous system development GO:0051962 178 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
microtubule organizing center organization GO:0031023 1 0.011
cell morphogenesis GO:0000902 142 0.011
early endosome to late endosome transport GO:0045022 2 0.011
multi organism reproductive process GO:0044703 262 0.011
regulation of protein modification process GO:0031399 194 0.011
cellular cation homeostasis GO:0030003 180 0.011
response to ethanol GO:0045471 162 0.011
ion transmembrane transport GO:0034220 365 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.011
calcium ion homeostasis GO:0055074 162 0.011
negative regulation of molecular function GO:0044092 133 0.011
regulation of peptide transport GO:0090087 87 0.011
cellular ion homeostasis GO:0006873 184 0.011
cell activation GO:0001775 97 0.011
cellular modified amino acid metabolic process GO:0006575 61 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
Rat
positive regulation of secretion by cell GO:1903532 128 0.011
blood circulation GO:0008015 183 0.011
Rat
single organism organelle organization GO:1902589 180 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
synaptic vesicle endocytosis GO:0048488 4 0.011
response to bacterium GO:0009617 200 0.011
membrane organization GO:0061024 94 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
rna localization GO:0006403 4 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
hormone transport GO:0009914 121 0.010
macroautophagy GO:0016236 4 0.010
negative regulation of cell proliferation GO:0008285 119 0.010
regulation of secretion by cell GO:1903530 208 0.010
cofactor metabolic process GO:0051186 95 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
response to external biotic stimulus GO:0043207 221 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
positive regulation of protein modification process GO:0031401 142 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
response to growth factor GO:0070848 189 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
protein modification by small protein conjugation or removal GO:0070647 35 0.010
cytoskeleton dependent cytokinesis GO:0061640 2 0.010
eye morphogenesis GO:0048592 4 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
positive regulation of secretion GO:0051047 140 0.010

Npepps disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
central nervous system disease DOID:331 0 0.013
muscular disease DOID:0080000 0 0.011
musculoskeletal system disease DOID:17 0 0.011
muscle tissue disease DOID:66 0 0.011