Rattus norvegicus

0 known processes

Insl6

insulin-like 6

Insl6 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
single organism biosynthetic process GO:0044711 342 0.259
cell motility GO:0048870 202 0.187
Mouse
positive regulation of multicellular organismal process GO:0051240 387 0.135
sexual reproduction GO:0019953 148 0.134
Mouse
response to oxygen levels GO:0070482 265 0.125
cell migration GO:0016477 197 0.124
cellular response to hormone stimulus GO:0032870 247 0.123
response to decreased oxygen levels GO:0036293 237 0.120
localization of cell GO:0051674 202 0.113
Mouse
multi organism reproductive process GO:0044703 262 0.106
Mouse
response to extracellular stimulus GO:0009991 380 0.098
response to insulin GO:0032868 133 0.090
response to nutrient levels GO:0031667 370 0.086
ovulation cycle process GO:0022602 50 0.080
cellular response to oxygen containing compound GO:1901701 386 0.079
response to hexose GO:0009746 144 0.076
programmed cell death GO:0012501 392 0.075
Mouse
response to hypoxia GO:0001666 231 0.075
carbohydrate derivative metabolic process GO:1901135 346 0.072
carboxylic acid metabolic process GO:0019752 289 0.071
regulation of cell differentiation GO:0045595 320 0.068
regulation of neurogenesis GO:0050767 247 0.067
positive regulation of developmental process GO:0051094 283 0.064
regulation of signal transduction GO:0009966 318 0.064
regulation of neuron differentiation GO:0045664 208 0.061
positive regulation of phosphorus metabolic process GO:0010562 262 0.061
response to acid chemical GO:0001101 222 0.061
response to estrogen GO:0043627 232 0.060
organonitrogen compound biosynthetic process GO:1901566 167 0.058
regulation of multicellular organismal development GO:2000026 376 0.057
regulation of molecular function GO:0065009 398 0.057
chemical homeostasis GO:0048878 292 0.057
protein phosphorylation GO:0006468 345 0.057
response to inorganic substance GO:0010035 377 0.057
regulation of nervous system development GO:0051960 264 0.056
regulation of cell projection organization GO:0031344 175 0.053
reproductive system development GO:0061458 128 0.051
Mouse
multicellular organism reproduction GO:0032504 233 0.051
Mouse
locomotion GO:0040011 237 0.050
Mouse
cell projection organization GO:0030030 302 0.050
response to vitamin GO:0033273 131 0.049
reproduction GO:0000003 245 0.049
Mouse
cellular response to fluid shear stress GO:0071498 4 0.047
regulation of cellular component organization GO:0051128 368 0.047
positive regulation of cell differentiation GO:0045597 217 0.046
cellular component movement GO:0006928 248 0.044
Mouse
response to molecule of bacterial origin GO:0002237 194 0.044
response to nutrient GO:0007584 248 0.044
organic acid metabolic process GO:0006082 292 0.043
multicellular organismal reproductive process GO:0048609 233 0.042
Mouse
cellular metal ion homeostasis GO:0006875 172 0.042
response to glucose GO:0009749 136 0.042
protein complex assembly GO:0006461 263 0.042
regulation of cellular protein metabolic process GO:0032268 267 0.040
protein complex subunit organization GO:0071822 302 0.039
response to alkaloid GO:0043279 132 0.038
positive regulation of molecular function GO:0044093 230 0.038
aging GO:0007568 241 0.038
regulation of cellular component movement GO:0051270 150 0.037
positive regulation of locomotion GO:0040017 102 0.037
positive regulation of cell motility GO:2000147 97 0.037
response to carbohydrate GO:0009743 183 0.036
gamete generation GO:0007276 124 0.036
Mouse
catabolic process GO:0009056 351 0.036
regulation of apoptotic process GO:0042981 335 0.036
Mouse
response to growth factor GO:0070848 189 0.036
regulation of programmed cell death GO:0043067 341 0.036
Mouse
cellular response to stress GO:0033554 269 0.036
macromolecular complex assembly GO:0065003 273 0.035
homeostatic process GO:0042592 331 0.035
cellular response to acid chemical GO:0071229 75 0.035
cation transport GO:0006812 382 0.035
positive regulation of cell migration GO:0030335 96 0.034
positive regulation of cellular component organization GO:0051130 200 0.034
neuron differentiation GO:0030182 368 0.033
negative regulation of metabolic process GO:0009892 331 0.032
cellular lipid metabolic process GO:0044255 208 0.032
signal transduction by phosphorylation GO:0023014 144 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.030
tissue development GO:0009888 252 0.030
positive regulation of cell proliferation GO:0008284 249 0.029
regulation of mapk cascade GO:0043408 116 0.029
single organism reproductive process GO:0044702 297 0.029
Mouse
macromolecular complex subunit organization GO:0043933 339 0.029
urogenital system development GO:0001655 78 0.029
reproductive process GO:0022414 372 0.029
Mouse
regulation of catalytic activity GO:0050790 304 0.029
cellular response to lipid GO:0071396 201 0.028
secretion GO:0046903 307 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
cellular amine metabolic process GO:0044106 38 0.027
amine metabolic process GO:0009308 38 0.027
reproductive structure development GO:0048608 128 0.027
Mouse
protein localization GO:0008104 191 0.027
macromolecule localization GO:0033036 252 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.027
response to vitamin d GO:0033280 34 0.026
mapk cascade GO:0000165 140 0.026
cytoskeleton organization GO:0007010 111 0.026
secretion by cell GO:0032940 248 0.026
regulation of cell proliferation GO:0042127 359 0.026
neuron projection development GO:0031175 273 0.026
cell type specific apoptotic process GO:0097285 134 0.026
glomerular epithelial cell differentiation GO:0072311 2 0.025
cellular ketone metabolic process GO:0042180 51 0.025
regeneration GO:0031099 163 0.025
positive regulation of nervous system development GO:0051962 178 0.025
developmental process involved in reproduction GO:0003006 159 0.025
Mouse
intracellular transport GO:0046907 185 0.025
regulation of system process GO:0044057 208 0.024
positive regulation of protein kinase activity GO:0045860 73 0.024
response to organophosphorus GO:0046683 102 0.024
response to metal ion GO:0010038 253 0.024
negative regulation of cell communication GO:0010648 158 0.024
regulation of phosphorylation GO:0042325 248 0.024
response to activity GO:0014823 73 0.024
cellular amide metabolic process GO:0043603 44 0.024
regulation of cellular localization GO:0060341 263 0.023
regulation of cell motility GO:2000145 131 0.023
response to corticosteroid GO:0031960 235 0.023
purine nucleotide metabolic process GO:0006163 229 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
response to estradiol GO:0032355 164 0.023
cellular component assembly GO:0022607 360 0.022
cellular chemical homeostasis GO:0055082 247 0.022
purine containing compound biosynthetic process GO:0072522 85 0.022
regulation of neuron projection development GO:0010975 161 0.022
limb morphogenesis GO:0035108 4 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
cellular response to alcohol GO:0097306 87 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
embryonic appendage morphogenesis GO:0035113 4 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
negative regulation of nucleic acid templated transcription GO:1903507 117 0.022
cellular component morphogenesis GO:0032989 155 0.022
sensory organ development GO:0007423 74 0.021
anatomical structure morphogenesis GO:0009653 298 0.021
protein complex biogenesis GO:0070271 263 0.021
regulation of anatomical structure morphogenesis GO:0022603 141 0.021
positive regulation of neuron differentiation GO:0045666 126 0.020
regulation of cell development GO:0060284 263 0.020
positive regulation of transport GO:0051050 245 0.020
appendage morphogenesis GO:0035107 4 0.020
response to temperature stimulus GO:0009266 94 0.020
cellular homeostasis GO:0019725 252 0.020
positive regulation of signaling GO:0023056 270 0.020
positive regulation of cell communication GO:0010647 271 0.020
positive regulation of apoptotic process GO:0043065 154 0.020
cellular response to iron iii ion GO:0071283 3 0.020
apoptotic process GO:0006915 381 0.020
Mouse
embryonic hindlimb morphogenesis GO:0035116 2 0.020
calcium ion homeostasis GO:0055074 162 0.020
oxoacid metabolic process GO:0043436 290 0.020
negative regulation of ion transport GO:0043271 51 0.019
nucleotide metabolic process GO:0009117 279 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
Mouse
cellular component biogenesis GO:0044085 368 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
regulation of transferase activity GO:0051338 123 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
female gonad development GO:0008585 53 0.018
cellular protein localization GO:0034613 122 0.018
cellular response to growth factor stimulus GO:0071363 162 0.018
smooth muscle cell migration GO:0014909 36 0.018
organophosphate metabolic process GO:0019637 370 0.018
regulation of cell migration GO:0030334 128 0.018
organ regeneration GO:0031100 101 0.018
cellular catabolic process GO:0044248 295 0.018
regulation of kinase activity GO:0043549 117 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
cell morphogenesis GO:0000902 142 0.018
response to biotic stimulus GO:0009607 226 0.018
cellular response to low density lipoprotein particle stimulus GO:0071404 3 0.018
positive regulation of cell projection organization GO:0031346 111 0.018
response to transition metal nanoparticle GO:1990267 122 0.017
central nervous system development GO:0007417 311 0.017
organelle organization GO:0006996 266 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
circulatory system development GO:0072359 134 0.017
spermatogenesis GO:0007283 99 0.017
Mouse
regulation of intracellular signal transduction GO:1902531 218 0.017
response to other organism GO:0051707 220 0.017
male gamete generation GO:0048232 99 0.017
Mouse
positive regulation of catalytic activity GO:0043085 184 0.017
endocrine system development GO:0035270 30 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.016
cyclic nucleotide metabolic process GO:0009187 80 0.016
regulation of smooth muscle cell migration GO:0014910 36 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
positive regulation of neuron projection development GO:0010976 99 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
response to monosaccharide GO:0034284 159 0.016
nucleoside phosphate biosynthetic process GO:1901293 102 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
cofactor metabolic process GO:0051186 95 0.016
response to oxidative stress GO:0006979 186 0.016
regulation of leukocyte differentiation GO:1902105 20 0.016
positive regulation of cellular component movement GO:0051272 102 0.016
protein oligomerization GO:0051259 191 0.016
response to peptide hormone GO:0043434 278 0.016
single organism catabolic process GO:0044712 283 0.016
kidney development GO:0001822 67 0.015
transcription dna templated GO:0006351 377 0.015
regulation of phosphate metabolic process GO:0019220 349 0.015
multicellular organism growth GO:0035264 1 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
response to nicotine GO:0035094 51 0.015
response to ethanol GO:0045471 162 0.015
regulation of dopamine secretion GO:0014059 15 0.015
regulation of protein kinase activity GO:0045859 105 0.015
regulation of locomotion GO:0040012 148 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
intracellular signal transduction GO:0035556 314 0.015
response to glucocorticoid GO:0051384 223 0.015
cellular response to insulin stimulus GO:0032869 81 0.015
response to amino acid GO:0043200 75 0.014
calcium ion transmembrane transport GO:0070588 70 0.014
purine containing compound metabolic process GO:0072521 253 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
rna metabolic process GO:0016070 406 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
response to camp GO:0051591 91 0.014
response to mechanical stimulus GO:0009612 134 0.014
positive regulation of kinase activity GO:0033674 77 0.014
regulation of protein metabolic process GO:0051246 289 0.014
regulation of membrane potential GO:0042391 110 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
organic acid transport GO:0015849 116 0.013
positive regulation of protein modification process GO:0031401 142 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
coenzyme metabolic process GO:0006732 86 0.013
regulation of transcription dna templated GO:0006355 374 0.013
response to retinoic acid GO:0032526 63 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
neuronal action potential GO:0019228 35 0.013
prostate gland epithelium morphogenesis GO:0060740 2 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
smooth muscle cell proliferation GO:0048659 77 0.013
regulation of protein modification process GO:0031399 194 0.013
response to peptide GO:1901652 292 0.013
wound healing GO:0042060 122 0.013
positive regulation of epithelial cell proliferation GO:0050679 32 0.012
cellular macromolecule localization GO:0070727 122 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
multicellular organismal signaling GO:0035637 44 0.012
fertilization GO:0009566 3 0.012
Mouse
neuron development GO:0048666 286 0.012
cellular response to glucose stimulus GO:0071333 65 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
regulation of immune system process GO:0002682 123 0.012
organic substance catabolic process GO:1901575 316 0.012
embryonic limb morphogenesis GO:0030326 4 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
response to low density lipoprotein particle GO:0055098 4 0.012
collagen catabolic process GO:0030574 2 0.012
muscle cell migration GO:0014812 36 0.012
response to wounding GO:0009611 254 0.012
prostate gland morphogenesis GO:0060512 2 0.012
transformation of host cell by virus GO:0019087 4 0.012
cellular response to hexose stimulus GO:0071331 65 0.011
molting cycle GO:0042303 3 0.011
eye morphogenesis GO:0048592 4 0.011
positive regulation of signal transduction GO:0009967 175 0.011
gonad development GO:0008406 104 0.011
Mouse
dna metabolic process GO:0006259 96 0.011
establishment of protein localization GO:0045184 141 0.011
sulfur compound metabolic process GO:0006790 70 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
adult locomotory behavior GO:0008344 4 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
regulation of protein serine threonine kinase activity GO:0071900 64 0.011
nucleic acid templated transcription GO:0097659 379 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
macromolecule catabolic process GO:0009057 58 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
transmission of nerve impulse GO:0019226 42 0.011
response to fluid shear stress GO:0034405 16 0.011
fatty acid metabolic process GO:0006631 99 0.011
hindlimb morphogenesis GO:0035137 2 0.011
myelination GO:0042552 39 0.011
cytoplasmic transport GO:0016482 115 0.010
blood vessel development GO:0001568 69 0.010
negative regulation of cell death GO:0060548 229 0.010
Mouse
regulation of vasculature development GO:1901342 44 0.010
activation of protein kinase activity GO:0032147 47 0.010
negative regulation of cellular metabolic process GO:0031324 281 0.010
regulation of rna biosynthetic process GO:2001141 381 0.010
male gonad development GO:0008584 59 0.010
Mouse
ras protein signal transduction GO:0007265 29 0.010

Insl6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
nervous system disease DOID:863 0 0.052
musculoskeletal system disease DOID:17 0 0.022
retinal disease DOID:5679 0 0.018
retinal degeneration DOID:8466 0 0.018
cone rod dystrophy DOID:0050572 0 0.018
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.018
eye disease DOID:5614 0 0.018