Rattus norvegicus

24 known processes

Arhgdia

Rho GDP dissociation inhibitor (GDI) alpha

(Aliases: MGC94886)

Arhgdia biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular protein metabolic process GO:0032268 267 0.133
protein complex assembly GO:0006461 263 0.130
protein complex subunit organization GO:0071822 302 0.114
macromolecular complex subunit organization GO:0043933 339 0.109
anatomical structure morphogenesis GO:0009653 298 0.104
cytoskeleton organization GO:0007010 111 0.092
cellular component assembly GO:0022607 360 0.080
regulation of cell differentiation GO:0045595 320 0.075
organelle organization GO:0006996 266 0.074
single organism organelle organization GO:1902589 180 0.070
response to oxygen levels GO:0070482 265 0.065
response to glucocorticoid GO:0051384 223 0.064
carboxylic acid metabolic process GO:0019752 289 0.059
regulation of protein metabolic process GO:0051246 289 0.056
actin cytoskeleton organization GO:0030036 73 0.055
actin filament based process GO:0030029 86 0.055
macromolecular complex assembly GO:0065003 273 0.053
programmed cell death GO:0012501 392 0.052
aging GO:0007568 241 0.051
regulation of multicellular organismal development GO:2000026 376 0.051
macromolecule localization GO:0033036 252 0.050
positive regulation of cell communication GO:0010647 271 0.048
single organism intracellular transport GO:1902582 166 0.047
response to corticosteroid GO:0031960 235 0.047
apoptotic process GO:0006915 381 0.047
cellular component movement GO:0006928 248 0.045
oxoacid metabolic process GO:0043436 290 0.044
vesicle mediated transport GO:0016192 181 0.043
endocytosis GO:0006897 84 0.043
cell cycle process GO:0022402 57 0.041
response to acid chemical GO:0001101 222 0.041
localization of cell GO:0051674 202 0.041
response to oxidative stress GO:0006979 186 0.039
response to extracellular stimulus GO:0009991 380 0.039
neuron differentiation GO:0030182 368 0.039
response to decreased oxygen levels GO:0036293 237 0.039
protein complex biogenesis GO:0070271 263 0.039
regulation of programmed cell death GO:0043067 341 0.038
response to nutrient levels GO:0031667 370 0.038
cellular component biogenesis GO:0044085 368 0.037
negative regulation of macromolecule metabolic process GO:0010605 260 0.037
regulation of cellular component organization GO:0051128 368 0.036
response to hypoxia GO:0001666 231 0.035
negative regulation of metabolic process GO:0009892 331 0.035
regulation of rna metabolic process GO:0051252 391 0.034
regulation of anatomical structure morphogenesis GO:0022603 141 0.033
reproductive process GO:0022414 372 0.033
organic acid metabolic process GO:0006082 292 0.033
central nervous system development GO:0007417 311 0.032
lipid metabolic process GO:0006629 283 0.031
cellular amino acid metabolic process GO:0006520 107 0.031
cellular response to stress GO:0033554 269 0.031
intracellular transport GO:0046907 185 0.030
behavior GO:0007610 205 0.030
cellular amine metabolic process GO:0044106 38 0.030
regulation of actin filament depolymerization GO:0030834 2 0.029
transmembrane transport GO:0055085 412 0.029
cellular ketone metabolic process GO:0042180 51 0.028
negative regulation of gene expression GO:0010629 199 0.028
cellular chemical homeostasis GO:0055082 247 0.028
immune system process GO:0002376 204 0.028
small gtpase mediated signal transduction GO:0007264 36 0.028
actin filament organization GO:0007015 42 0.028
response to cytokine GO:0034097 215 0.028
regulation of cell morphogenesis GO:0022604 77 0.028
regulation of catalytic activity GO:0050790 304 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
regulation of organelle organization GO:0033043 80 0.027
cellular component morphogenesis GO:0032989 155 0.027
amine metabolic process GO:0009308 38 0.027
negative regulation of signaling GO:0023057 157 0.027
circulatory system development GO:0072359 134 0.026
head development GO:0060322 247 0.026
regulation of intracellular signal transduction GO:1902531 218 0.025
positive regulation of organelle organization GO:0010638 48 0.025
regulation of apoptotic process GO:0042981 335 0.025
negative regulation of apoptotic process GO:0043066 181 0.025
negative regulation of protein metabolic process GO:0051248 114 0.024
protein phosphorylation GO:0006468 345 0.024
regulation of cell development GO:0060284 263 0.024
positive regulation of cell death GO:0010942 184 0.024
positive regulation of developmental process GO:0051094 283 0.024
regulation of signal transduction GO:0009966 318 0.024
cell activation GO:0001775 97 0.024
response to ethanol GO:0045471 162 0.023
single organism reproductive process GO:0044702 297 0.023
response to wounding GO:0009611 254 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
anatomical structure formation involved in morphogenesis GO:0048646 83 0.023
cellular response to hydroperoxide GO:0071447 2 0.023
ion homeostasis GO:0050801 212 0.023
positive regulation of cellular protein metabolic process GO:0032270 167 0.023
regulation of molecular function GO:0065009 398 0.023
response to inorganic substance GO:0010035 377 0.022
cellular lipid metabolic process GO:0044255 208 0.022
cellular calcium ion homeostasis GO:0006874 160 0.022
chemical homeostasis GO:0048878 292 0.022
positive regulation of protein modification process GO:0031401 142 0.022
cell projection organization GO:0030030 302 0.022
regulation of system process GO:0044057 208 0.022
muscle system process GO:0003012 115 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
cellular cation homeostasis GO:0030003 180 0.021
homeostatic process GO:0042592 331 0.021
cellular macromolecular complex assembly GO:0034622 58 0.021
nucleotide metabolic process GO:0009117 279 0.021
regulation of locomotion GO:0040012 148 0.021
cell motility GO:0048870 202 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
regulation of membrane potential GO:0042391 110 0.020
single organism biosynthetic process GO:0044711 342 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
tissue development GO:0009888 252 0.019
regulation of neurogenesis GO:0050767 247 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
proteolysis GO:0006508 175 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
cardiovascular system development GO:0072358 134 0.019
protein transport GO:0015031 132 0.019
defense response GO:0006952 194 0.019
heart morphogenesis GO:0003007 3 0.019
protein oligomerization GO:0051259 191 0.019
ras protein signal transduction GO:0007265 29 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
calcium ion homeostasis GO:0055074 162 0.019
regulation of neuron differentiation GO:0045664 208 0.018
regulation of phosphorylation GO:0042325 248 0.018
olfactory behavior GO:0042048 2 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
response to growth factor GO:0070848 189 0.018
regulation of mapk cascade GO:0043408 116 0.018
regulation of actin cytoskeleton organization GO:0032956 30 0.018
regulation of anatomical structure size GO:0090066 135 0.018
lipid biosynthetic process GO:0008610 128 0.018
actin filament bundle organization GO:0061572 19 0.018
neural tube formation GO:0001841 1 0.018
regulation of synaptic transmission GO:0050804 141 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
multi organism reproductive process GO:0044703 262 0.017
protein localization GO:0008104 191 0.017
cellular ion homeostasis GO:0006873 184 0.017
multi multicellular organism process GO:0044706 138 0.017
tube development GO:0035295 89 0.017
negative regulation of nervous system development GO:0051961 79 0.017
organic substance catabolic process GO:1901575 316 0.017
positive regulation of programmed cell death GO:0043068 157 0.017
chemosensory behavior GO:0007635 2 0.017
response to peptide hormone GO:0043434 278 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
neuron projection development GO:0031175 273 0.017
dendrite morphogenesis GO:0048813 43 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
growth GO:0040007 165 0.017
protein import into nucleus GO:0006606 35 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
mapk cascade GO:0000165 140 0.016
ion transmembrane transport GO:0034220 365 0.016
response to alkaloid GO:0043279 132 0.016
response to biotic stimulus GO:0009607 226 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
regulation of mrna splicing via spliceosome GO:0048024 3 0.016
response to estrogen GO:0043627 232 0.016
muscle structure development GO:0061061 87 0.016
spindle organization GO:0007051 2 0.016
response to carbohydrate GO:0009743 183 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.016
tube formation GO:0035148 3 0.016
response to ketone GO:1901654 182 0.016
regulation of cytoskeleton organization GO:0051493 49 0.016
positive regulation of cellular component movement GO:0051272 102 0.015
regulation of reactive oxygen species metabolic process GO:2000377 26 0.015
protein localization to organelle GO:0033365 57 0.015
negative regulation of cell differentiation GO:0045596 99 0.015
cytoplasmic transport GO:0016482 115 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
anion transport GO:0006820 178 0.015
cellular protein complex assembly GO:0043623 44 0.015
intracellular signal transduction GO:0035556 314 0.015
reproduction GO:0000003 245 0.015
cellular homeostasis GO:0019725 252 0.015
single organism behavior GO:0044708 130 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
regulation of nervous system development GO:0051960 264 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
multicellular organism reproduction GO:0032504 233 0.015
epithelium development GO:0060429 96 0.015
anterior posterior pattern specification GO:0009952 1 0.015
muscle cell differentiation GO:0042692 52 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
cation transport GO:0006812 382 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
action potential GO:0001508 54 0.015
dendrite development GO:0016358 72 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
positive regulation of transport GO:0051050 245 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
response to external biotic stimulus GO:0043207 221 0.014
actin filament depolymerization GO:0030042 3 0.014
positive regulation of signal transduction GO:0009967 175 0.014
negative regulation of cell communication GO:0010648 158 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
regulation of actin filament based process GO:0032970 42 0.014
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.014
regulation of cellular localization GO:0060341 263 0.014
metal ion homeostasis GO:0055065 186 0.014
inflammatory response GO:0006954 150 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
organ morphogenesis GO:0009887 75 0.014
positive regulation of response to external stimulus GO:0032103 51 0.013
positive regulation of signaling GO:0023056 270 0.013
cellular response to hypoxia GO:0071456 51 0.013
brain development GO:0007420 247 0.013
transmission of nerve impulse GO:0019226 42 0.013
regulation of behavior GO:0050795 61 0.013
regulation of dna metabolic process GO:0051052 60 0.013
sexual reproduction GO:0019953 148 0.013
heart development GO:0007507 72 0.013
protein homooligomerization GO:0051260 91 0.013
morphogenesis of embryonic epithelium GO:0016331 3 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
cellular macromolecule localization GO:0070727 122 0.013
axis specification GO:0009798 4 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
response to amino acid GO:0043200 75 0.013
negative regulation of cell death GO:0060548 229 0.013
organic anion transport GO:0015711 132 0.013
regulation of cell size GO:0008361 37 0.013
neurological system process GO:0050877 219 0.013
cell projection morphogenesis GO:0048858 123 0.013
organophosphate metabolic process GO:0019637 370 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
response to fatty acid GO:0070542 65 0.012
single organism catabolic process GO:0044712 283 0.012
negative regulation of developmental process GO:0051093 125 0.012
neuronal action potential GO:0019228 35 0.012
regulation of muscle system process GO:0090257 79 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
regulation of dendrite development GO:0050773 59 0.012
regulation of immune system process GO:0002682 123 0.012
response to monosaccharide GO:0034284 159 0.012
response to nutrient GO:0007584 248 0.012
protein heterooligomerization GO:0051291 89 0.012
spermatogenesis GO:0007283 99 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
neuron development GO:0048666 286 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
regulation of neuron projection development GO:0010975 161 0.012
alcohol metabolic process GO:0006066 77 0.012
regulation of cell motility GO:2000145 131 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
fatty acid metabolic process GO:0006631 99 0.012
regeneration GO:0031099 163 0.012
developmental growth GO:0048589 100 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.011
muscle cell proliferation GO:0033002 84 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
response to metal ion GO:0010038 253 0.011
actin filament branching GO:0090135 1 0.011
regulation of homeostatic process GO:0032844 101 0.011
regulation of hydrolase activity GO:0051336 143 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
gamete generation GO:0007276 124 0.011
cell cycle GO:0007049 101 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
regulation of cell projection organization GO:0031344 175 0.011
carboxylic acid transport GO:0046942 115 0.011
gliogenesis GO:0042063 93 0.011
nucleotide catabolic process GO:0009166 139 0.011
cell migration GO:0016477 197 0.011
regulation of cellular component size GO:0032535 51 0.011
ossification GO:0001503 70 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
regulation of cell proliferation GO:0042127 359 0.011
regulation of peptide transport GO:0090087 87 0.011
mitotic spindle organization GO:0007052 2 0.011
dna metabolic process GO:0006259 96 0.011
gastrulation GO:0007369 2 0.011
negative regulation of molecular function GO:0044092 133 0.011
cellular catabolic process GO:0044248 295 0.011
positive regulation of behavior GO:0048520 38 0.011
actin filament polymerization GO:0030041 11 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
lipid storage GO:0019915 1 0.011
reproductive system development GO:0061458 128 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
positive regulation of cell development GO:0010720 176 0.010
negative regulation of transport GO:0051051 136 0.010
regulation of actin polymerization or depolymerization GO:0008064 12 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
salivary gland development GO:0007431 3 0.010
positive regulation of cellular biosynthetic process GO:0031328 295 0.010
striated muscle tissue development GO:0014706 58 0.010
peptidyl amino acid modification GO:0018193 126 0.010
fertilization GO:0009566 3 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
biological adhesion GO:0022610 110 0.010
signal transduction by phosphorylation GO:0023014 144 0.010
catabolic process GO:0009056 351 0.010
negative regulation of cell cycle phase transition GO:1901988 4 0.010
regulation of rna biosynthetic process GO:2001141 381 0.010
g protein coupled receptor signaling pathway GO:0007186 242 0.010
intracellular protein transport GO:0006886 79 0.010

Arhgdia disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.038
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
organ system cancer DOID:0050686 0 0.023
central nervous system disease DOID:331 0 0.014
muscular disease DOID:0080000 0 0.012
musculoskeletal system disease DOID:17 0 0.012
sensory system disease DOID:0050155 0 0.011