Rattus norvegicus

0 known processes

Adam22

a disintegrin and metalloprotease domain (ADAM) 22

(Aliases: MDC2)

Adam22 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 391 0.100
regulation of transcription dna templated GO:0006355 374 0.088
positive regulation of biosynthetic process GO:0009891 319 0.080
rna metabolic process GO:0016070 406 0.077
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.076
negative regulation of multicellular organismal process GO:0051241 203 0.070
cellular response to oxygen containing compound GO:1901701 386 0.065
positive regulation of transcription dna templated GO:0045893 197 0.059
regulation of nucleic acid templated transcription GO:1903506 380 0.051
regulation of neuron differentiation GO:0045664 208 0.051
positive regulation of cellular biosynthetic process GO:0031328 295 0.049
secretion GO:0046903 307 0.049
regulation of rna biosynthetic process GO:2001141 381 0.049
regulation of neuron projection development GO:0010975 161 0.049
negative regulation of macromolecule metabolic process GO:0010605 260 0.047
response to wounding GO:0009611 254 0.045
positive regulation of gene expression GO:0010628 244 0.045
intracellular signal transduction GO:0035556 314 0.044
nucleic acid templated transcription GO:0097659 379 0.041
protein phosphorylation GO:0006468 345 0.041
rna biosynthetic process GO:0032774 380 0.041
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.041
negative regulation of cell communication GO:0010648 158 0.040
regulation of cellular amine metabolic process GO:0033238 8 0.039
regulation of nervous system development GO:0051960 264 0.037
positive regulation of rna biosynthetic process GO:1902680 197 0.037
positive regulation of molecular function GO:0044093 230 0.036
transcription dna templated GO:0006351 377 0.035
regulation of neurogenesis GO:0050767 247 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.033
secretion by cell GO:0032940 248 0.031
neuron death GO:0070997 127 0.031
negative regulation of metabolic process GO:0009892 331 0.031
regulation of multicellular organismal development GO:2000026 376 0.031
positive regulation of cell development GO:0010720 176 0.030
regulation of signal transduction GO:0009966 318 0.029
regulation of cell development GO:0060284 263 0.028
cellular amine metabolic process GO:0044106 38 0.028
synaptic transmission GO:0007268 235 0.028
negative regulation of gene expression GO:0010629 199 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
positive regulation of neurogenesis GO:0050769 165 0.028
positive regulation of cell differentiation GO:0045597 217 0.027
positive regulation of protein phosphorylation GO:0001934 135 0.027
negative regulation of nucleic acid templated transcription GO:1903507 117 0.027
positive regulation of phosphate metabolic process GO:0045937 262 0.026
positive regulation of rna metabolic process GO:0051254 203 0.026
amine metabolic process GO:0009308 38 0.026
cell projection organization GO:0030030 302 0.025
regulation of mapk cascade GO:0043408 116 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
regulation of phosphorylation GO:0042325 248 0.024
single organism reproductive process GO:0044702 297 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.024
cellular component biogenesis GO:0044085 368 0.024
regulation of cell differentiation GO:0045595 320 0.024
head development GO:0060322 247 0.024
positive regulation of developmental process GO:0051094 283 0.024
coenzyme metabolic process GO:0006732 86 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.023
negative regulation of signaling GO:0023057 157 0.023
purine containing compound metabolic process GO:0072521 253 0.023
organelle organization GO:0006996 266 0.022
anterior posterior pattern specification GO:0009952 1 0.022
nucleotide metabolic process GO:0009117 279 0.021
regulation of cellular localization GO:0060341 263 0.021
rhythmic process GO:0048511 156 0.021
cellular component assembly GO:0022607 360 0.021
ribonucleotide biosynthetic process GO:0009260 85 0.021
positive regulation of protein modification process GO:0031401 142 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
response to growth factor GO:0070848 189 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
axis specification GO:0009798 4 0.020
negative regulation of response to stimulus GO:0048585 155 0.020
regulation of synaptic transmission GO:0050804 141 0.020
positive regulation of nervous system development GO:0051962 178 0.020
embryonic skeletal system morphogenesis GO:0048704 3 0.020
aging GO:0007568 241 0.020
circadian rhythm GO:0007623 88 0.020
cellular amino acid metabolic process GO:0006520 107 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
multi organism reproductive process GO:0044703 262 0.019
regulation of cellular component organization GO:0051128 368 0.019
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.019
cell cell signaling GO:0007267 335 0.019
negative regulation of nervous system development GO:0051961 79 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
regulation of cell projection organization GO:0031344 175 0.019
cyclic nucleotide metabolic process GO:0009187 80 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
negative regulation of neurogenesis GO:0050768 78 0.018
transmembrane transport GO:0055085 412 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
response to ammonium ion GO:0060359 71 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
cellular response to endogenous stimulus GO:0071495 377 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
negative regulation of neuron differentiation GO:0045665 62 0.017
positive regulation of neuron projection development GO:0010976 99 0.017
response to axon injury GO:0048678 59 0.017
response to peptide hormone GO:0043434 278 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
regulation of dendrite development GO:0050773 59 0.016
negative regulation of signal transduction GO:0009968 83 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
reactive oxygen species metabolic process GO:0072593 37 0.016
learning or memory GO:0007611 90 0.016
multicellular organism reproduction GO:0032504 233 0.016
transcription from rna polymerase ii promoter GO:0006366 252 0.016
synaptic growth at neuromuscular junction GO:0051124 1 0.016
embryonic pattern specification GO:0009880 1 0.016
regulation of molecular function GO:0065009 398 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
amide transport GO:0042886 105 0.015
chromosome segregation GO:0007059 2 0.015
organ formation GO:0048645 3 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
regulation of synaptic plasticity GO:0048167 70 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
reproductive process GO:0022414 372 0.015
inorganic cation transmembrane transport GO:0098662 202 0.015
negative regulation of transcription dna templated GO:0045892 116 0.014
neuron projection development GO:0031175 273 0.014
response to temperature stimulus GO:0009266 94 0.014
development of primary sexual characteristics GO:0045137 107 0.014
growth GO:0040007 165 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
programmed cell death GO:0012501 392 0.014
cellular response to stress GO:0033554 269 0.014
cofactor metabolic process GO:0051186 95 0.014
negative regulation of phosphate metabolic process GO:0045936 80 0.014
embryonic skeletal system development GO:0048706 3 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
metal ion transport GO:0030001 289 0.014
ras protein signal transduction GO:0007265 29 0.014
sensory organ development GO:0007423 74 0.014
positive regulation of response to stimulus GO:0048584 285 0.013
regulation of secretion by cell GO:1903530 208 0.013
regulation of growth GO:0040008 105 0.013
neuron fate commitment GO:0048663 4 0.013
sex differentiation GO:0007548 113 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
neural crest cell differentiation GO:0014033 2 0.013
dorsal ventral axon guidance GO:0033563 1 0.013
camp metabolic process GO:0046058 63 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
brain development GO:0007420 247 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
cation transmembrane transport GO:0098655 263 0.013
regulation of protein modification process GO:0031399 194 0.013
reproduction GO:0000003 245 0.013
developmental growth GO:0048589 100 0.013
reactive nitrogen species metabolic process GO:2001057 1 0.013
tissue development GO:0009888 252 0.012
behavior GO:0007610 205 0.012
regulation of secretion GO:0051046 224 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
proteolysis GO:0006508 175 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
response to nutrient levels GO:0031667 370 0.012
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.012
ovulation cycle GO:0042698 67 0.012
heart morphogenesis GO:0003007 3 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
embryonic axis specification GO:0000578 1 0.012
response to extracellular stimulus GO:0009991 380 0.012
regulation of protein metabolic process GO:0051246 289 0.012
intracellular transport GO:0046907 185 0.012
response to ethanol GO:0045471 162 0.012
central nervous system development GO:0007417 311 0.012
signal release GO:0023061 145 0.012
sequestering of metal ion GO:0051238 9 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
cell motility GO:0048870 202 0.011
hormone secretion GO:0046879 115 0.011
catabolic process GO:0009056 351 0.011
adult locomotory behavior GO:0008344 4 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
somatic stem cell maintenance GO:0035019 2 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.011
regulation of phosphate metabolic process GO:0019220 349 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
cellular homeostasis GO:0019725 252 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
single organism intracellular transport GO:1902582 166 0.011
response to peptide GO:1901652 292 0.011
negative regulation of developmental process GO:0051093 125 0.011
response to glucose GO:0009749 136 0.011
response to acid chemical GO:0001101 222 0.010
positive regulation of signaling GO:0023056 270 0.010
regulation of membrane potential GO:0042391 110 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
apoptotic process GO:0006915 381 0.010
synapse assembly GO:0007416 29 0.010
nitrogen compound transport GO:0071705 229 0.010
dendrite development GO:0016358 72 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
response to heat GO:0009408 60 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
cellular response to acid chemical GO:0071229 75 0.010
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
cardiac ventricle development GO:0003231 1 0.010

Adam22 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014