Rattus norvegicus

0 known processes

Ifit1

interferon-induced protein with tetratricopeptide repeats 1

(Aliases: Garg16)

Ifit1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to extracellular stimulus GO:0009991 380 0.247
response to nutrient levels GO:0031667 370 0.241
cellular response to oxygen containing compound GO:1901701 386 0.229
response to inorganic substance GO:0010035 377 0.228
immune system process GO:0002376 204 0.227
Human
cellular response to lipid GO:0071396 201 0.217
neuron projection development GO:0031175 273 0.147
response to oxygen levels GO:0070482 265 0.133
response to glucocorticoid GO:0051384 223 0.128
fatty acid derivative metabolic process GO:1901568 38 0.126
cation homeostasis GO:0055080 195 0.119
cellular response to organic cyclic compound GO:0071407 202 0.115
Human
regulation of protein metabolic process GO:0051246 289 0.112
apoptotic process GO:0006915 381 0.112
regulation of cell proliferation GO:0042127 359 0.111
cellular response to endogenous stimulus GO:0071495 377 0.109
small molecule biosynthetic process GO:0044283 124 0.106
g protein coupled receptor signaling pathway GO:0007186 242 0.103
transcription dna templated GO:0006351 377 0.100
immune response GO:0006955 104 0.099
Human
hormone transport GO:0009914 121 0.086
circulatory system process GO:0003013 183 0.084
protein phosphorylation GO:0006468 345 0.083
carboxylic acid metabolic process GO:0019752 289 0.083
response to cytokine GO:0034097 215 0.083
Human Mouse
negative regulation of cell death GO:0060548 229 0.082
developmental process involved in reproduction GO:0003006 159 0.082
regulation of protein phosphorylation GO:0001932 183 0.076
blood circulation GO:0008015 183 0.074
cellular homeostasis GO:0019725 252 0.073
organic acid metabolic process GO:0006082 292 0.073
regulation of cellular localization GO:0060341 263 0.072
central nervous system development GO:0007417 311 0.071
positive regulation of cell proliferation GO:0008284 249 0.071
positive regulation of cell communication GO:0010647 271 0.071
response to peptide GO:1901652 292 0.070
response to peptide hormone GO:0043434 278 0.069
carbohydrate derivative metabolic process GO:1901135 346 0.068
intracellular signal transduction GO:0035556 314 0.068
oxoacid metabolic process GO:0043436 290 0.068
response to biotic stimulus GO:0009607 226 0.067
Human Mouse
divalent inorganic cation homeostasis GO:0072507 165 0.067
unsaturated fatty acid metabolic process GO:0033559 39 0.067
positive regulation of response to stimulus GO:0048584 285 0.066
reproductive process GO:0022414 372 0.066
response to molecule of bacterial origin GO:0002237 194 0.065
cellular response to stress GO:0033554 269 0.065
regulation of multicellular organismal development GO:2000026 376 0.063
tissue development GO:0009888 252 0.063
neuron differentiation GO:0030182 368 0.062
response to acid chemical GO:0001101 222 0.062
regulation of programmed cell death GO:0043067 341 0.061
brain development GO:0007420 247 0.060
fatty acid metabolic process GO:0006631 99 0.060
cell projection organization GO:0030030 302 0.059
nitrogen compound transport GO:0071705 229 0.059
response to organophosphorus GO:0046683 102 0.058
positive regulation of signaling GO:0023056 270 0.058
stress activated protein kinase signaling cascade GO:0031098 37 0.057
positive regulation of cellular biosynthetic process GO:0031328 295 0.057
positive regulation of intracellular signal transduction GO:1902533 138 0.057
mapk cascade GO:0000165 140 0.056
regulation of phosphorus metabolic process GO:0051174 349 0.056
negative regulation of cellular metabolic process GO:0031324 281 0.055
aging GO:0007568 241 0.055
cell motility GO:0048870 202 0.054
regulation of transcription dna templated GO:0006355 374 0.053
negative regulation of multicellular organismal process GO:0051241 203 0.053
intracellular transport GO:0046907 185 0.052
Human
amide transport GO:0042886 105 0.052
carboxylic acid transport GO:0046942 115 0.052
regulation of cellular component organization GO:0051128 368 0.051
nucleoside phosphate metabolic process GO:0006753 283 0.050
cellular cation homeostasis GO:0030003 180 0.049
positive regulation of multicellular organismal process GO:0051240 387 0.049
response to mechanical stimulus GO:0009612 134 0.049
regulation of apoptotic process GO:0042981 335 0.048
regulation of cellular component movement GO:0051270 150 0.047
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.047
cellular response to tumor necrosis factor GO:0071356 46 0.047
growth GO:0040007 165 0.047
localization of cell GO:0051674 202 0.047
cellular response to organonitrogen compound GO:0071417 197 0.047
regulation of cell motility GO:2000145 131 0.046
rna metabolic process GO:0016070 406 0.045
positive regulation of cellular component organization GO:0051130 200 0.045
inflammatory response GO:0006954 150 0.045
hormone secretion GO:0046879 115 0.044
positive regulation of signal transduction GO:0009967 175 0.044
positive regulation of homeostatic process GO:0032846 49 0.044
protein localization GO:0008104 191 0.044
Human
regulation of cellular protein metabolic process GO:0032268 267 0.044
cellular metal ion homeostasis GO:0006875 172 0.043
lipid metabolic process GO:0006629 283 0.043
homeostatic process GO:0042592 331 0.043
Human
regulation of phosphate metabolic process GO:0019220 349 0.043
cellular ketone metabolic process GO:0042180 51 0.042
regulation of hormone secretion GO:0046883 106 0.041
nucleotide metabolic process GO:0009117 279 0.041
peptide transport GO:0015833 97 0.041
regulation of hormone levels GO:0010817 187 0.041
signal transduction by phosphorylation GO:0023014 144 0.041
positive regulation of biosynthetic process GO:0009891 319 0.040
cellular ion homeostasis GO:0006873 184 0.040
response to nutrient GO:0007584 248 0.039
carboxylic acid biosynthetic process GO:0046394 83 0.039
response to wounding GO:0009611 254 0.038
regulation of catalytic activity GO:0050790 304 0.038
Human
programmed cell death GO:0012501 392 0.038
cellular chemical homeostasis GO:0055082 247 0.038
positive regulation of phosphorus metabolic process GO:0010562 262 0.038
synaptic transmission GO:0007268 235 0.037
reproductive system development GO:0061458 128 0.037
regulation of secretion GO:0051046 224 0.036
regulation of phosphorylation GO:0042325 248 0.036
negative regulation of phosphorus metabolic process GO:0010563 80 0.036
cellular response to external stimulus GO:0071496 118 0.036
response to growth factor GO:0070848 189 0.035
response to lipopolysaccharide GO:0032496 191 0.035
chemical homeostasis GO:0048878 292 0.035
Human
regulation of mapk cascade GO:0043408 116 0.035
response to corticosteroid GO:0031960 235 0.035
negative regulation of gene expression GO:0010629 199 0.035
locomotion GO:0040011 237 0.034
positive regulation of jnk cascade GO:0046330 13 0.034
single organism intracellular transport GO:1902582 166 0.034
negative regulation of response to stimulus GO:0048585 155 0.034
Human
positive regulation of phosphorylation GO:0042327 177 0.034
catabolic process GO:0009056 351 0.034
cell migration GO:0016477 197 0.033
positive regulation of nucleotide metabolic process GO:0045981 91 0.033
regulation of immune system process GO:0002682 123 0.033
Human
nucleobase containing small molecule metabolic process GO:0055086 316 0.033
response to purine containing compound GO:0014074 126 0.032
carbohydrate metabolic process GO:0005975 130 0.032
response to radiation GO:0009314 137 0.032
cell cell signaling GO:0007267 335 0.032
regulation of neuron projection development GO:0010975 161 0.032
metal ion homeostasis GO:0055065 186 0.032
positive regulation of molecular function GO:0044093 230 0.031
positive regulation of catalytic activity GO:0043085 184 0.031
ion homeostasis GO:0050801 212 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.031
cytosolic calcium ion homeostasis GO:0051480 140 0.031
icosanoid metabolic process GO:0006690 38 0.031
cellular response to hormone stimulus GO:0032870 247 0.031
regulation of nervous system development GO:0051960 264 0.030
response to transforming growth factor beta GO:0071559 46 0.030
cellular calcium ion homeostasis GO:0006874 160 0.030
transcription from rna polymerase ii promoter GO:0006366 252 0.030
regulation of protein kinase activity GO:0045859 105 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
response to bacterium GO:0009617 200 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.030
positive regulation of programmed cell death GO:0043068 157 0.029
response to carbohydrate GO:0009743 183 0.029
cellular response to steroid hormone stimulus GO:0071383 93 0.029
rna biosynthetic process GO:0032774 380 0.029
regulation of molecular function GO:0065009 398 0.029
Human
negative regulation of metabolic process GO:0009892 331 0.029
Human
positive regulation of immune system process GO:0002684 90 0.028
regulation of protein modification process GO:0031399 194 0.028
single organism carbohydrate metabolic process GO:0044723 118 0.028
organ regeneration GO:0031100 101 0.028
response to reactive oxygen species GO:0000302 120 0.028
macromolecular complex subunit organization GO:0043933 339 0.028
cellular divalent inorganic cation homeostasis GO:0072503 162 0.028
multi organism reproductive process GO:0044703 262 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
cellular component assembly GO:0022607 360 0.027
cellular component movement GO:0006928 248 0.027
carbohydrate derivative biosynthetic process GO:1901137 124 0.026
response to oxidative stress GO:0006979 186 0.026
positive regulation of cell death GO:0010942 184 0.026
regulation of jnk cascade GO:0046328 19 0.026
regulation of anatomical structure size GO:0090066 135 0.026
regulation of secretion by cell GO:1903530 208 0.026
head development GO:0060322 247 0.026
regulation of neuron differentiation GO:0045664 208 0.025
renal system development GO:0072001 67 0.025
negative regulation of phosphate metabolic process GO:0045936 80 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.025
positive regulation of cellular protein metabolic process GO:0032270 167 0.025
sensory perception GO:0007600 101 0.024
reactive oxygen species metabolic process GO:0072593 37 0.024
positive regulation of apoptotic process GO:0043065 154 0.024
cellular response to molecule of bacterial origin GO:0071219 56 0.024
regulation of system process GO:0044057 208 0.024
cellular response to abiotic stimulus GO:0071214 85 0.024
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.024
regulation of locomotion GO:0040012 148 0.024
signal release GO:0023061 145 0.024
anion transport GO:0006820 178 0.023
multi multicellular organism process GO:0044706 138 0.023
regulation of homeostatic process GO:0032844 101 0.023
response to other organism GO:0051707 220 0.023
Human Mouse
epithelial cell differentiation GO:0030855 71 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.023
response to ionizing radiation GO:0010212 59 0.023
response to metal ion GO:0010038 253 0.023
amine metabolic process GO:0009308 38 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
Human
response to estradiol GO:0032355 164 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
negative regulation of signaling GO:0023057 157 0.022
regulation of cell development GO:0060284 263 0.022
response to zinc ion GO:0010043 39 0.022
female pregnancy GO:0007565 122 0.022
positive regulation of developmental process GO:0051094 283 0.022
regulation of signal transduction GO:0009966 318 0.022
single organism biosynthetic process GO:0044711 342 0.022
multicellular organismal signaling GO:0035637 44 0.022
neuron development GO:0048666 286 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
response to vitamin GO:0033273 131 0.021
positive regulation of transport GO:0051050 245 0.021
protein complex subunit organization GO:0071822 302 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
regulation of hydrolase activity GO:0051336 143 0.021
Human
ras protein signal transduction GO:0007265 29 0.021
regulation of response to stress GO:0080134 126 0.021
Human
monocarboxylic acid metabolic process GO:0032787 152 0.021
regulation of pancreatic stellate cell proliferation GO:2000229 2 0.021
purine containing compound metabolic process GO:0072521 253 0.021
positive regulation of hydrolase activity GO:0051345 86 0.021
metal ion transport GO:0030001 289 0.021
peptide secretion GO:0002790 86 0.021
small gtpase mediated signal transduction GO:0007264 36 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.020
organic anion transport GO:0015711 132 0.020
negative regulation of cellular protein metabolic process GO:0032269 106 0.020
positive regulation of gene expression GO:0010628 244 0.020
monocarboxylic acid biosynthetic process GO:0072330 48 0.020
regulation of ion homeostasis GO:2000021 63 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
cellular component biogenesis GO:0044085 368 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
regulation of synaptic transmission GO:0050804 141 0.020
calcium ion homeostasis GO:0055074 162 0.020
secretion GO:0046903 307 0.020
secretion by cell GO:0032940 248 0.020
positive regulation of stress activated protein kinase signaling cascade GO:0070304 17 0.020
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
organic substance catabolic process GO:1901575 316 0.019
regulation of cell differentiation GO:0045595 320 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
reactive nitrogen species metabolic process GO:2001057 1 0.019
gonad development GO:0008406 104 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
regulation of stress activated mapk cascade GO:0032872 23 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
anatomical structure morphogenesis GO:0009653 298 0.019
alcohol metabolic process GO:0006066 77 0.018
immune effector process GO:0002252 53 0.018
Human
negative regulation of hormone secretion GO:0046888 46 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
response to estrogen GO:0043627 232 0.018
positive regulation of mapk cascade GO:0043410 92 0.018
negative regulation of response to external stimulus GO:0032102 37 0.018
Human
response to hypoxia GO:0001666 231 0.018
regulation of intracellular transport GO:0032386 65 0.018
positive regulation of cell development GO:0010720 176 0.018
regulation of neurogenesis GO:0050767 247 0.018
regulation of response to wounding GO:1903034 69 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
positive regulation of protein metabolic process GO:0051247 178 0.017
regulation of body fluid levels GO:0050878 90 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
response to monosaccharide GO:0034284 159 0.017
regulation of cell migration GO:0030334 128 0.017
cellular amine metabolic process GO:0044106 38 0.017
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.017
nucleic acid templated transcription GO:0097659 379 0.017
response to interleukin 15 GO:0070672 4 0.017
neurotransmitter uptake GO:0001504 3 0.017
response to external biotic stimulus GO:0043207 221 0.016
Human Mouse
regulation of reactive oxygen species metabolic process GO:2000377 26 0.016
transmission of nerve impulse GO:0019226 42 0.016
single organism reproductive process GO:0044702 297 0.016
positive regulation of stress activated mapk cascade GO:0032874 17 0.016
cellular carbohydrate metabolic process GO:0044262 72 0.016
pancreatic stellate cell proliferation GO:0072343 2 0.016
multicellular organism reproduction GO:0032504 233 0.016
regulation of ion transport GO:0043269 245 0.016
negative regulation of peptide hormone secretion GO:0090278 30 0.016
organophosphate metabolic process GO:0019637 370 0.016
vitamin transport GO:0051180 14 0.016
telencephalon development GO:0021537 62 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
negative regulation of protein phosphorylation GO:0001933 44 0.016
regulation of rna biosynthetic process GO:2001141 381 0.016
cellular catabolic process GO:0044248 295 0.016
positive regulation of protein modification process GO:0031401 142 0.016
rhythmic process GO:0048511 156 0.016
peptide hormone secretion GO:0030072 84 0.015
peptidyl amino acid modification GO:0018193 126 0.015
macromolecule localization GO:0033036 252 0.015
Human
regulation of vasculature development GO:1901342 44 0.015
positive regulation of nervous system development GO:0051962 178 0.015
cellular response to biotic stimulus GO:0071216 59 0.015
negative regulation of secretion GO:0051048 82 0.015
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
ion transmembrane transport GO:0034220 365 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
sequestering of metal ion GO:0051238 9 0.015
muscle contraction GO:0006936 88 0.015
receptor metabolic process GO:0043112 18 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
regeneration GO:0031099 163 0.015
regulation of cytoskeleton organization GO:0051493 49 0.015
aromatic compound catabolic process GO:0019439 168 0.015
regulation of peptide transport GO:0090087 87 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
cation transport GO:0006812 382 0.015
cytoplasmic transport GO:0016482 115 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
response to decreased oxygen levels GO:0036293 237 0.015
regulation of blood circulation GO:1903522 110 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
regulation of cellular response to stress GO:0080135 49 0.014
nicotinamide nucleotide metabolic process GO:0046496 28 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.014
forebrain development GO:0030900 98 0.014
cellular response to acid chemical GO:0071229 75 0.014
cellular component morphogenesis GO:0032989 155 0.014
response to ketone GO:1901654 182 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 12 0.014
camp metabolic process GO:0046058 63 0.014
negative regulation of molecular function GO:0044092 133 0.013
Human
eye development GO:0001654 50 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
neuropeptide signaling pathway GO:0007218 29 0.013
regulation of peptide hormone secretion GO:0090276 80 0.013
development of primary male sexual characteristics GO:0046546 59 0.013
cellular response to peptide GO:1901653 133 0.013
vesicle mediated transport GO:0016192 181 0.013
regulation of cell projection organization GO:0031344 175 0.013
sex differentiation GO:0007548 113 0.013
sensory perception of pain GO:0019233 73 0.013
defense response GO:0006952 194 0.013
Human
single organism catabolic process GO:0044712 283 0.013
kidney development GO:0001822 67 0.013
insulin secretion GO:0030073 69 0.013
cellular response to reactive oxygen species GO:0034614 55 0.013
lipid biosynthetic process GO:0008610 128 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
circadian rhythm GO:0007623 88 0.013
response to light stimulus GO:0009416 52 0.013
calcium ion transport GO:0006816 131 0.013
dna metabolic process GO:0006259 96 0.012
regulation of phagocytosis engulfment GO:0060099 4 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
vascular process in circulatory system GO:0003018 96 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
negative regulation of chronic inflammatory response GO:0002677 2 0.012
negative regulation of secretion by cell GO:1903531 72 0.012
dephosphorylation GO:0016311 98 0.012
organic acid biosynthetic process GO:0016053 83 0.012
leukocyte migration GO:0050900 38 0.012
macromolecular complex assembly GO:0065003 273 0.012
protein heterooligomerization GO:0051291 89 0.012
neurological system process GO:0050877 219 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
Human Mouse
negative regulation of luteinizing hormone secretion GO:0033685 4 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
positive regulation of cell migration GO:0030335 96 0.012
cell growth GO:0016049 104 0.012
negative regulation of transport GO:0051051 136 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
Human
positive regulation of neuron differentiation GO:0045666 126 0.012
proteolysis GO:0006508 175 0.012
response to tumor necrosis factor GO:0034612 56 0.012
response to hydrogen peroxide GO:0042542 89 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
regulation of blood pressure GO:0008217 83 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
organelle localization GO:0051640 55 0.011
heart process GO:0003015 57 0.011
response to insulin GO:0032868 133 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
negative regulation of cell communication GO:0010648 158 0.011
cellular response to lipopolysaccharide GO:0071222 55 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
erk1 and erk2 cascade GO:0070371 48 0.011
stress activated mapk cascade GO:0051403 35 0.011
camp biosynthetic process GO:0006171 47 0.011
response to hyperoxia GO:0055093 45 0.011
prostaglandin metabolic process GO:0006693 12 0.011
leukocyte activation GO:0045321 76 0.011
male gonad development GO:0008584 59 0.011
positive regulation of intracellular transport GO:0032388 39 0.011
neuronal action potential GO:0019228 35 0.011
response to toxic substance GO:0009636 133 0.011
development of primary sexual characteristics GO:0045137 107 0.011
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.011
regulation of transferase activity GO:0051338 123 0.011
divalent inorganic cation transport GO:0072511 134 0.011
organic hydroxy compound biosynthetic process GO:1901617 51 0.011
cofactor metabolic process GO:0051186 95 0.010
response to glucose GO:0009749 136 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
organelle organization GO:0006996 266 0.010
transmembrane transport GO:0055085 412 0.010
negative regulation of developmental process GO:0051093 125 0.010
protein oligomerization GO:0051259 191 0.010
response to alkaloid GO:0043279 132 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
cognition GO:0050890 92 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010

Ifit1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.036
cancer DOID:162 0 0.030
disease of cellular proliferation DOID:14566 0 0.030
organ system cancer DOID:0050686 0 0.030
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
inherited metabolic disorder DOID:655 0 0.015
gastrointestinal system cancer DOID:3119 0 0.014
central nervous system disease DOID:331 0 0.014