Rattus norvegicus

0 known processes

Klhl21

kelch-like 21 (Drosophila)

(Aliases: RGD1305863)

Klhl21 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 391 0.064
regulation of molecular function GO:0065009 398 0.056
rna metabolic process GO:0016070 406 0.046
programmed cell death GO:0012501 392 0.043
transcription dna templated GO:0006351 377 0.043
regulation of nucleic acid templated transcription GO:1903506 380 0.043
rna biosynthetic process GO:0032774 380 0.042
nucleic acid templated transcription GO:0097659 379 0.041
transcription from rna polymerase ii promoter GO:0006366 252 0.040
regulation of transcription dna templated GO:0006355 374 0.040
negative regulation of metabolic process GO:0009892 331 0.036
Rat
regulation of catalytic activity GO:0050790 304 0.035
regulation of rna biosynthetic process GO:2001141 381 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.034
apoptotic process GO:0006915 381 0.034
regulation of protein metabolic process GO:0051246 289 0.033
regulation of multicellular organismal development GO:2000026 376 0.032
Rat
single organism reproductive process GO:0044702 297 0.030
transmembrane transport GO:0055085 412 0.030
regulation of cellular protein metabolic process GO:0032268 267 0.029
reproductive process GO:0022414 372 0.029
regulation of cell differentiation GO:0045595 320 0.029
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.029
cellular amino acid metabolic process GO:0006520 107 0.029
central nervous system development GO:0007417 311 0.028
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
Rat
ion transmembrane transport GO:0034220 365 0.027
regulation of signal transduction GO:0009966 318 0.027
organic acid metabolic process GO:0006082 292 0.026
Rat
organic substance catabolic process GO:1901575 316 0.026
cation transport GO:0006812 382 0.026
intracellular signal transduction GO:0035556 314 0.026
cellular amine metabolic process GO:0044106 38 0.026
positive regulation of gene expression GO:0010628 244 0.026
protein phosphorylation GO:0006468 345 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
cellular ketone metabolic process GO:0042180 51 0.025
regulation of programmed cell death GO:0043067 341 0.025
oxoacid metabolic process GO:0043436 290 0.025
Rat
anterior posterior pattern specification GO:0009952 1 0.025
cell projection organization GO:0030030 302 0.024
Rat
regulation of apoptotic process GO:0042981 335 0.023
cellular catabolic process GO:0044248 295 0.023
response to inorganic substance GO:0010035 377 0.023
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
protein complex assembly GO:0006461 263 0.023
Rat
cation transmembrane transport GO:0098655 263 0.022
macromolecular complex subunit organization GO:0043933 339 0.022
Rat
homeostatic process GO:0042592 331 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
positive regulation of cellular protein metabolic process GO:0032270 167 0.022
amine metabolic process GO:0009308 38 0.022
proteolysis GO:0006508 175 0.022
single organism catabolic process GO:0044712 283 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
catabolic process GO:0009056 351 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
regulation of phosphate metabolic process GO:0019220 349 0.021
neuron differentiation GO:0030182 368 0.021
Rat
anatomical structure morphogenesis GO:0009653 298 0.021
negative regulation of gene expression GO:0010629 199 0.021
Rat
regulation of phosphorylation GO:0042325 248 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
organelle organization GO:0006996 266 0.020
Rat
regulation of cellular localization GO:0060341 263 0.020
Rat
cellular component biogenesis GO:0044085 368 0.020
Rat
positive regulation of molecular function GO:0044093 230 0.020
regulation of nervous system development GO:0051960 264 0.020
Rat
multicellular organismal reproductive process GO:0048609 233 0.020
secretion GO:0046903 307 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
Rat
cardiac chamber development GO:0003205 1 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
cellular response to stress GO:0033554 269 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
organonitrogen compound catabolic process GO:1901565 179 0.019
metal ion transport GO:0030001 289 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
regulation of protein modification process GO:0031399 194 0.019
heart morphogenesis GO:0003007 3 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
multi organism reproductive process GO:0044703 262 0.019
negative regulation of cell death GO:0060548 229 0.019
regulation of proteasomal protein catabolic process GO:0061136 4 0.018
gastrulation GO:0007369 2 0.018
neuron projection development GO:0031175 273 0.018
Rat
brain development GO:0007420 247 0.018
Rat
response to nutrient levels GO:0031667 370 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
nitrogen compound transport GO:0071705 229 0.018
nucleotide metabolic process GO:0009117 279 0.018
carboxylic acid metabolic process GO:0019752 289 0.018
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.018
tissue development GO:0009888 252 0.018
purine containing compound metabolic process GO:0072521 253 0.018
multicellular organism reproduction GO:0032504 233 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
Rat
positive regulation of protein metabolic process GO:0051247 178 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
chemical homeostasis GO:0048878 292 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
cellular component morphogenesis GO:0032989 155 0.017
inorganic cation transmembrane transport GO:0098662 202 0.017
anion transport GO:0006820 178 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
organophosphate metabolic process GO:0019637 370 0.016
cellular homeostasis GO:0019725 252 0.016
regulation of hydrolase activity GO:0051336 143 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
regulation of cell proliferation GO:0042127 359 0.016
regulation of cell development GO:0060284 263 0.016
Rat
aging GO:0007568 241 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
macromolecule localization GO:0033036 252 0.016
Human Rat
axis specification GO:0009798 4 0.015
response to extracellular stimulus GO:0009991 380 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
reproduction GO:0000003 245 0.015
regulation of neuron differentiation GO:0045664 208 0.015
Rat
negative regulation of molecular function GO:0044092 133 0.015
regulation of ion transport GO:0043269 245 0.015
response to peptide hormone GO:0043434 278 0.015
embryonic pattern specification GO:0009880 1 0.015
cellular chemical homeostasis GO:0055082 247 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
positive regulation of cell communication GO:0010647 271 0.015
nucleoside metabolic process GO:0009116 179 0.015
protein complex biogenesis GO:0070271 263 0.015
Rat
cellular response to nitrogen compound GO:1901699 210 0.015
lipid metabolic process GO:0006629 283 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.014
organic anion transport GO:0015711 132 0.014
muscle system process GO:0003012 115 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
response to oxygen levels GO:0070482 265 0.014
neuron development GO:0048666 286 0.014
Rat
positive regulation of cell development GO:0010720 176 0.014
Rat
cellular response to organonitrogen compound GO:0071417 197 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
head development GO:0060322 247 0.014
Rat
regulation of cellular component organization GO:0051128 368 0.014
Rat
positive regulation of developmental process GO:0051094 283 0.014
Rat
positive regulation of nervous system development GO:0051962 178 0.014
Rat
positive regulation of signaling GO:0023056 270 0.014
response to oxidative stress GO:0006979 186 0.014
heterocycle catabolic process GO:0046700 167 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
cardiac ventricle development GO:0003231 1 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
response to peptide GO:1901652 292 0.014
macromolecular complex assembly GO:0065003 273 0.014
Rat
ion homeostasis GO:0050801 212 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
circulatory system process GO:0003013 183 0.014
regulation of neurogenesis GO:0050767 247 0.013
Rat
response to decreased oxygen levels GO:0036293 237 0.013
regulation of membrane potential GO:0042391 110 0.013
mesoderm development GO:0007498 2 0.013
regulation of hormone levels GO:0010817 187 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
ras protein signal transduction GO:0007265 29 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
Rat
developmental process involved in reproduction GO:0003006 159 0.013
sexual reproduction GO:0019953 148 0.013
synaptic transmission GO:0007268 235 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
regulation of transferase activity GO:0051338 123 0.013
protein complex subunit organization GO:0071822 302 0.013
Rat
cellular ion homeostasis GO:0006873 184 0.013
carbohydrate metabolic process GO:0005975 130 0.013
single organism organelle organization GO:1902589 180 0.013
Rat
action potential GO:0001508 54 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
regulation of cell projection organization GO:0031344 175 0.012
Rat
regulation of catabolic process GO:0009894 113 0.012
negative regulation of cell communication GO:0010648 158 0.012
response to cytokine GO:0034097 215 0.012
response to estrogen GO:0043627 232 0.012
cellular component assembly GO:0022607 360 0.012
Rat
positive regulation of cellular component organization GO:0051130 200 0.012
Rat
neurological system process GO:0050877 219 0.012
cell cycle checkpoint GO:0000075 2 0.012
response to hexose GO:0009746 144 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
protein oligomerization GO:0051259 191 0.012
Rat
cell cell signaling GO:0007267 335 0.012
regulation of system process GO:0044057 208 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
response to biotic stimulus GO:0009607 226 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
multicellular organism growth GO:0035264 1 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
positive regulation of protein modification process GO:0031401 142 0.012
protein modification by small protein conjugation or removal GO:0070647 35 0.012
Human
carbohydrate derivative catabolic process GO:1901136 147 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
chromosome segregation GO:0007059 2 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
regulation of neuron projection development GO:0010975 161 0.012
Rat
purine nucleoside catabolic process GO:0006152 124 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
heart development GO:0007507 72 0.011
response to hypoxia GO:0001666 231 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
cation homeostasis GO:0055080 195 0.011
cell cycle GO:0007049 101 0.011
Human
reproductive system development GO:0061458 128 0.011
single organism intracellular transport GO:1902582 166 0.011
Rat
reproductive structure development GO:0048608 128 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
locomotion GO:0040011 237 0.011
response to glucocorticoid GO:0051384 223 0.011
spindle organization GO:0007051 2 0.011
single organism biosynthetic process GO:0044711 342 0.011
negative regulation of transport GO:0051051 136 0.011
Rat
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
cell projection morphogenesis GO:0048858 123 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
embryonic axis specification GO:0000578 1 0.011
cell type specific apoptotic process GO:0097285 134 0.011
response to carbohydrate GO:0009743 183 0.011
intracellular transport GO:0046907 185 0.011
Rat
carboxylic acid transport GO:0046942 115 0.011
regulation of secretion GO:0051046 224 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
Rat
cell part morphogenesis GO:0032990 123 0.011
response to metal ion GO:0010038 253 0.011
Rat
cellular cation homeostasis GO:0030003 180 0.011
gamete generation GO:0007276 124 0.011
response to acid chemical GO:0001101 222 0.011
positive regulation of signal transduction GO:0009967 175 0.011
positive regulation of cell death GO:0010942 184 0.011
defense response GO:0006952 194 0.011
negative regulation of signaling GO:0023057 157 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
dna metabolic process GO:0006259 96 0.010
blood circulation GO:0008015 183 0.010
ossification GO:0001503 70 0.010
spermatogenesis GO:0007283 99 0.010
regulation of kinase activity GO:0043549 117 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
positive regulation of transport GO:0051050 245 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
Rat
metal ion homeostasis GO:0055065 186 0.010
oxidation reduction process GO:0055114 304 0.010
cellular response to peptide GO:1901653 133 0.010
neuron projection morphogenesis GO:0048812 122 0.010
regulation of blood circulation GO:1903522 110 0.010
growth GO:0040007 165 0.010
male gamete generation GO:0048232 99 0.010
glycosyl compound catabolic process GO:1901658 126 0.010
macromolecule catabolic process GO:0009057 58 0.010

Klhl21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
musculoskeletal system disease DOID:17 0 0.023
muscular disease DOID:0080000 0 0.017
muscle tissue disease DOID:66 0 0.017
myopathy DOID:423 0 0.013
cardiovascular system disease DOID:1287 0 0.011