Rattus norvegicus

0 known processes

Adamtsl3

ADAMTS-like 3

Adamtsl3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.066
carboxylic acid metabolic process GO:0019752 289 0.062
oxoacid metabolic process GO:0043436 290 0.055
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.048
single organism biosynthetic process GO:0044711 342 0.045
programmed cell death GO:0012501 392 0.044
regulation of molecular function GO:0065009 398 0.044
organophosphate metabolic process GO:0019637 370 0.042
regulation of rna biosynthetic process GO:2001141 381 0.040
intracellular signal transduction GO:0035556 314 0.039
response to inorganic substance GO:0010035 377 0.039
regulation of phosphorus metabolic process GO:0051174 349 0.038
rna biosynthetic process GO:0032774 380 0.038
rna metabolic process GO:0016070 406 0.038
regulation of cell proliferation GO:0042127 359 0.038
regulation of rna metabolic process GO:0051252 391 0.037
response to extracellular stimulus GO:0009991 380 0.037
cellular amino acid metabolic process GO:0006520 107 0.037
amine metabolic process GO:0009308 38 0.037
nucleic acid templated transcription GO:0097659 379 0.036
cellular component biogenesis GO:0044085 368 0.036
regulation of transcription dna templated GO:0006355 374 0.035
positive regulation of biosynthetic process GO:0009891 319 0.035
regulation of apoptotic process GO:0042981 335 0.035
apoptotic process GO:0006915 381 0.035
organelle organization GO:0006996 266 0.034
regulation of programmed cell death GO:0043067 341 0.034
regulation of cell differentiation GO:0045595 320 0.034
regulation of nucleic acid templated transcription GO:1903506 380 0.034
cellular component assembly GO:0022607 360 0.034
regulation of phosphate metabolic process GO:0019220 349 0.034
catabolic process GO:0009056 351 0.033
regulation of protein metabolic process GO:0051246 289 0.033
cellular amine metabolic process GO:0044106 38 0.033
positive regulation of multicellular organismal process GO:0051240 387 0.033
regulation of multicellular organismal development GO:2000026 376 0.033
cellular ketone metabolic process GO:0042180 51 0.033
regulation of catalytic activity GO:0050790 304 0.033
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
lipid metabolic process GO:0006629 283 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
transcription dna templated GO:0006351 377 0.032
protein complex subunit organization GO:0071822 302 0.032
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
cell projection organization GO:0030030 302 0.031
regulation of cellular component organization GO:0051128 368 0.031
response to nutrient levels GO:0031667 370 0.031
response to nutrient GO:0007584 248 0.031
negative regulation of metabolic process GO:0009892 331 0.031
macromolecular complex subunit organization GO:0043933 339 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.030
reproductive process GO:0022414 372 0.030
negative regulation of cellular metabolic process GO:0031324 281 0.030
neuron differentiation GO:0030182 368 0.030
locomotion GO:0040011 237 0.030
nucleotide metabolic process GO:0009117 279 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
central nervous system development GO:0007417 311 0.030
regulation of cell development GO:0060284 263 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
regulation of signal transduction GO:0009966 318 0.029
cell cell signaling GO:0007267 335 0.029
positive regulation of phosphate metabolic process GO:0045937 262 0.029
regulation of nervous system development GO:0051960 264 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
positive regulation of cell communication GO:0010647 271 0.028
protein phosphorylation GO:0006468 345 0.028
neuron projection development GO:0031175 273 0.028
response to peptide GO:1901652 292 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.027
cellular response to stress GO:0033554 269 0.027
regulation of neurogenesis GO:0050767 247 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
cellular catabolic process GO:0044248 295 0.027
organic substance catabolic process GO:1901575 316 0.027
positive regulation of signaling GO:0023056 270 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
single organism organelle organization GO:1902589 180 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
cell motility GO:0048870 202 0.026
positive regulation of molecular function GO:0044093 230 0.026
homeostatic process GO:0042592 331 0.026
positive regulation of cell differentiation GO:0045597 217 0.026
single organism reproductive process GO:0044702 297 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
response to peptide hormone GO:0043434 278 0.026
positive regulation of gene expression GO:0010628 244 0.026
response to oxygen levels GO:0070482 265 0.026
neurological system process GO:0050877 219 0.026
brain development GO:0007420 247 0.025
transcription from rna polymerase ii promoter GO:0006366 252 0.025
single organism catabolic process GO:0044712 283 0.025
response to estrogen GO:0043627 232 0.025
chemical homeostasis GO:0048878 292 0.025
regulation of phosphorylation GO:0042325 248 0.025
response to acid chemical GO:0001101 222 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
localization of cell GO:0051674 202 0.025
positive regulation of developmental process GO:0051094 283 0.025
cell migration GO:0016477 197 0.025
neuron development GO:0048666 286 0.024
protein complex assembly GO:0006461 263 0.024
secretion GO:0046903 307 0.024
cation transport GO:0006812 382 0.024
head development GO:0060322 247 0.024
multi organism reproductive process GO:0044703 262 0.023
response to cytokine GO:0034097 215 0.023
protein complex biogenesis GO:0070271 263 0.023
transmembrane transport GO:0055085 412 0.023
purine nucleotide metabolic process GO:0006163 229 0.023
reproduction GO:0000003 245 0.022
macromolecular complex assembly GO:0065003 273 0.022
regulation of neuron differentiation GO:0045664 208 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
response to metal ion GO:0010038 253 0.022
cellular component movement GO:0006928 248 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
purine containing compound metabolic process GO:0072521 253 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
macromolecule localization GO:0033036 252 0.021
immune system process GO:0002376 204 0.021
negative regulation of cell death GO:0060548 229 0.021
cellular lipid metabolic process GO:0044255 208 0.021
regulation of intracellular signal transduction GO:1902531 218 0.021
cellular chemical homeostasis GO:0055082 247 0.021
response to decreased oxygen levels GO:0036293 237 0.021
response to hypoxia GO:0001666 231 0.021
aging GO:0007568 241 0.021
cellular homeostasis GO:0019725 252 0.021
negative regulation of gene expression GO:0010629 199 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
tissue development GO:0009888 252 0.021
cellular cation homeostasis GO:0030003 180 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
response to oxidative stress GO:0006979 186 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
defense response GO:0006952 194 0.020
metal ion transport GO:0030001 289 0.020
cellular ion homeostasis GO:0006873 184 0.020
multicellular organism reproduction GO:0032504 233 0.020
regulation of cellular localization GO:0060341 263 0.019
metal ion homeostasis GO:0055065 186 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
calcium ion homeostasis GO:0055074 162 0.019
regulation of cell projection organization GO:0031344 175 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
response to corticosteroid GO:0031960 235 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
response to wounding GO:0009611 254 0.019
ion homeostasis GO:0050801 212 0.019
intracellular transport GO:0046907 185 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
response to molecule of bacterial origin GO:0002237 194 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
response to external biotic stimulus GO:0043207 221 0.019
synaptic transmission GO:0007268 235 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
regulation of protein modification process GO:0031399 194 0.019
g protein coupled receptor signaling pathway GO:0007186 242 0.019
response to lipopolysaccharide GO:0032496 191 0.019
positive regulation of nervous system development GO:0051962 178 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
cation homeostasis GO:0055080 195 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
protein localization GO:0008104 191 0.018
anterior posterior pattern specification GO:0009952 1 0.018
positive regulation of cell development GO:0010720 176 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
single organism carbohydrate metabolic process GO:0044723 118 0.017
regulation of secretion by cell GO:1903530 208 0.017
monocarboxylic acid metabolic process GO:0032787 152 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
response to growth factor GO:0070848 189 0.017
carbohydrate metabolic process GO:0005975 130 0.017
oxidation reduction process GO:0055114 304 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
small molecule biosynthetic process GO:0044283 124 0.017
regulation of neuron projection development GO:0010975 161 0.017
regulation of immune system process GO:0002682 123 0.017
response to ethanol GO:0045471 162 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
blood circulation GO:0008015 183 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
response to bacterium GO:0009617 200 0.017
regulation of membrane potential GO:0042391 110 0.017
response to glucocorticoid GO:0051384 223 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
cellular response to lipid GO:0071396 201 0.017
positive regulation of transport GO:0051050 245 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
response to other organism GO:0051707 220 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
regulation of ion transport GO:0043269 245 0.016
regulation of hydrolase activity GO:0051336 143 0.016
proteolysis GO:0006508 175 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
peptidyl amino acid modification GO:0018193 126 0.016
ion transmembrane transport GO:0034220 365 0.016
regulation of system process GO:0044057 208 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
mapk cascade GO:0000165 140 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
actin filament based process GO:0030029 86 0.016
gland development GO:0048732 155 0.016
positive regulation of protein modification process GO:0031401 142 0.015
negative regulation of molecular function GO:0044092 133 0.015
secretion by cell GO:0032940 248 0.015
nucleoside metabolic process GO:0009116 179 0.015
protein oligomerization GO:0051259 191 0.015
organic hydroxy compound metabolic process GO:1901615 115 0.015
rhythmic process GO:0048511 156 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
positive regulation of cell death GO:0010942 184 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
cellular protein localization GO:0034613 122 0.015
cellular response to cytokine stimulus GO:0071345 127 0.015
multi multicellular organism process GO:0044706 138 0.015
heart morphogenesis GO:0003007 3 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
cytoskeleton organization GO:0007010 111 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
regulation of anatomical structure size GO:0090066 135 0.015
circulatory system process GO:0003013 183 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
response to ketone GO:1901654 182 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
response to biotic stimulus GO:0009607 226 0.015
circulatory system development GO:0072359 134 0.015
response to purine containing compound GO:0014074 126 0.014
cellular component morphogenesis GO:0032989 155 0.014
establishment of protein localization GO:0045184 141 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
inflammatory response GO:0006954 150 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
ras protein signal transduction GO:0007265 29 0.014
single organism intracellular transport GO:1902582 166 0.014
regulation of transferase activity GO:0051338 123 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
cell cycle checkpoint GO:0000075 2 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
positive regulation of signal transduction GO:0009967 175 0.014
negative regulation of transport GO:0051051 136 0.014
cell morphogenesis GO:0000902 142 0.014
cellular macromolecule localization GO:0070727 122 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
aromatic compound catabolic process GO:0019439 168 0.014
calcium ion transport GO:0006816 131 0.014
muscle system process GO:0003012 115 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
divalent inorganic cation transport GO:0072511 134 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
negative regulation of developmental process GO:0051093 125 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
response to estradiol GO:0032355 164 0.014
vesicle mediated transport GO:0016192 181 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
regulation of response to stress GO:0080134 126 0.014
cellular response to peptide GO:1901653 133 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
regulation of kinase activity GO:0043549 117 0.013
behavior GO:0007610 205 0.013
heterocycle catabolic process GO:0046700 167 0.013
regulation of secretion GO:0051046 224 0.013
lipid biosynthetic process GO:0008610 128 0.013
negative regulation of cell communication GO:0010648 158 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
regulation of neuron death GO:1901214 115 0.013
divalent metal ion transport GO:0070838 132 0.013
growth GO:0040007 165 0.013
gastrulation GO:0007369 2 0.013
response to alkaloid GO:0043279 132 0.013
sexual reproduction GO:0019953 148 0.013
response to radiation GO:0009314 137 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
axis specification GO:0009798 4 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
cardiovascular system development GO:0072358 134 0.013
response to vitamin GO:0033273 131 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
organophosphate catabolic process GO:0046434 148 0.013
response to carbohydrate GO:0009743 183 0.013
regeneration GO:0031099 163 0.013
regulation of cell migration GO:0030334 128 0.013
reactive nitrogen species metabolic process GO:2001057 1 0.013
chromosome segregation GO:0007059 2 0.013
nitrogen compound transport GO:0071705 229 0.013
fatty acid metabolic process GO:0006631 99 0.013
negative regulation of signaling GO:0023057 157 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
developmental process involved in reproduction GO:0003006 159 0.012
regulation of homeostatic process GO:0032844 101 0.012
regulation of hormone levels GO:0010817 187 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
regulation of locomotion GO:0040012 148 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
cytokine biosynthetic process GO:0042089 3 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
protein transport GO:0015031 132 0.012
eye morphogenesis GO:0048592 4 0.012
purine containing compound catabolic process GO:0072523 138 0.012
signal release GO:0023061 145 0.012
cell projection morphogenesis GO:0048858 123 0.012
nucleotide catabolic process GO:0009166 139 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
regulation of metal ion transport GO:0010959 118 0.012
response to camp GO:0051591 91 0.012
action potential GO:0001508 54 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
regulation of cellular component movement GO:0051270 150 0.012
gamete generation GO:0007276 124 0.012
muscle cell proliferation GO:0033002 84 0.012
regulation of catabolic process GO:0009894 113 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
regulation of synaptic transmission GO:0050804 141 0.012
multicellular organismal signaling GO:0035637 44 0.012
cell cycle GO:0007049 101 0.012
transmission of nerve impulse GO:0019226 42 0.012
response to reactive oxygen species GO:0000302 120 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
neuron death GO:0070997 127 0.012
organic acid biosynthetic process GO:0016053 83 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
spindle organization GO:0007051 2 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
response to organophosphorus GO:0046683 102 0.012
reproductive system development GO:0061458 128 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
cation transmembrane transport GO:0098655 263 0.012
regulation of cell motility GO:2000145 131 0.011
female pregnancy GO:0007565 122 0.011
response to mechanical stimulus GO:0009612 134 0.011
immune response GO:0006955 104 0.011
reproductive structure development GO:0048608 128 0.011
positive regulation of immune system process GO:0002684 90 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
spermatogenesis GO:0007283 99 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
cellular response to external stimulus GO:0071496 118 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
cell type specific apoptotic process GO:0097285 134 0.011
response to toxic substance GO:0009636 133 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
neuronal action potential GO:0019228 35 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
response to hexose GO:0009746 144 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
regulation of protein kinase activity GO:0045859 105 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
regulation of mapk cascade GO:0043408 116 0.011
positive regulation of ion transport GO:0043270 94 0.011
membrane organization GO:0061024 94 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
male gamete generation GO:0048232 99 0.011
response to amino acid GO:0043200 75 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
mesoderm development GO:0007498 2 0.011
alcohol metabolic process GO:0006066 77 0.011
multicellular organism growth GO:0035264 1 0.011
epithelium development GO:0060429 96 0.011
regulation of response to external stimulus GO:0032101 106 0.011
cell part morphogenesis GO:0032990 123 0.011
sex differentiation GO:0007548 113 0.011
salivary gland development GO:0007431 3 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
embryonic pattern specification GO:0009880 1 0.011
forebrain development GO:0030900 98 0.011
development of primary sexual characteristics GO:0045137 107 0.011
response to glucose GO:0009749 136 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
lipid storage GO:0019915 1 0.011
axon development GO:0061564 96 0.011
cell activation GO:0001775 97 0.011
actin cytoskeleton organization GO:0030036 73 0.010
sensory perception GO:0007600 101 0.010
anion transport GO:0006820 178 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
hormone secretion GO:0046879 115 0.010
regulation of growth GO:0040008 105 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
sequestering of calcium ion GO:0051208 8 0.010
sequestering of metal ion GO:0051238 9 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
maintenance of location GO:0051235 17 0.010
neuron projection morphogenesis GO:0048812 122 0.010
cytoplasmic transport GO:0016482 115 0.010
dna metabolic process GO:0006259 96 0.010
gonad development GO:0008406 104 0.010
response to insulin GO:0032868 133 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
cellular carbohydrate metabolic process GO:0044262 72 0.010
hepaticobiliary system development GO:0061008 90 0.010
single organism cellular localization GO:1902580 102 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
liver development GO:0001889 90 0.010
positive regulation of transferase activity GO:0051347 81 0.010
positive regulation of secretion GO:0051047 140 0.010
regulation of cytokine biosynthetic process GO:0042035 3 0.010
vascular process in circulatory system GO:0003018 96 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
negative regulation of cell proliferation GO:0008285 119 0.010

Adamtsl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.031
disease of metabolism DOID:0014667 0 0.015
sensory system disease DOID:0050155 0 0.014
central nervous system disease DOID:331 0 0.013
cardiovascular system disease DOID:1287 0 0.012
musculoskeletal system disease DOID:17 0 0.012
eye and adnexa disease DOID:1492 0 0.010