Rattus norvegicus

0 known processes

Adamtsl4

ADAMTS-like 4

(Aliases: MGC116260,Tsrc1)

Adamtsl4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to endogenous stimulus GO:0071495 377 0.152
reproductive process GO:0022414 372 0.112
cellular response to organic cyclic compound GO:0071407 202 0.096
cellular response to hormone stimulus GO:0032870 247 0.090
macromolecular complex assembly GO:0065003 273 0.084
cellular response to nitrogen compound GO:1901699 210 0.082
response to growth factor GO:0070848 189 0.080
regulation of phosphate metabolic process GO:0019220 349 0.073
response to cytokine GO:0034097 215 0.069
rna biosynthetic process GO:0032774 380 0.069
intracellular signal transduction GO:0035556 314 0.068
apoptotic process GO:0006915 381 0.068
defense response GO:0006952 194 0.064
response to corticosteroid GO:0031960 235 0.064
cellular response to lipid GO:0071396 201 0.063
response to oxygen levels GO:0070482 265 0.063
localization of cell GO:0051674 202 0.062
positive regulation of multicellular organismal process GO:0051240 387 0.061
regulation of cell proliferation GO:0042127 359 0.061
response to metal ion GO:0010038 253 0.059
positive regulation of cellular component movement GO:0051272 102 0.057
positive regulation of developmental process GO:0051094 283 0.056
blood circulation GO:0008015 183 0.056
cellular response to oxygen containing compound GO:1901701 386 0.055
response to estrogen GO:0043627 232 0.054
cellular component biogenesis GO:0044085 368 0.053
multi multicellular organism process GO:0044706 138 0.053
response to wounding GO:0009611 254 0.053
cell migration GO:0016477 197 0.051
negative regulation of cellular metabolic process GO:0031324 281 0.050
cellular component assembly GO:0022607 360 0.050
response to nutrient levels GO:0031667 370 0.049
response to nutrient GO:0007584 248 0.049
cellular response to organonitrogen compound GO:0071417 197 0.048
response to ketone GO:1901654 182 0.047
cell motility GO:0048870 202 0.047
regulation of protein metabolic process GO:0051246 289 0.046
catabolic process GO:0009056 351 0.045
regulation of cell development GO:0060284 263 0.045
regulation of cell differentiation GO:0045595 320 0.044
regulation of rna metabolic process GO:0051252 391 0.043
nucleotide metabolic process GO:0009117 279 0.042
response to inorganic substance GO:0010035 377 0.042
response to decreased oxygen levels GO:0036293 237 0.042
positive regulation of cell development GO:0010720 176 0.042
response to acid chemical GO:0001101 222 0.042
protein complex subunit organization GO:0071822 302 0.041
positive regulation of signaling GO:0023056 270 0.041
locomotion GO:0040011 237 0.041
nucleobase containing small molecule metabolic process GO:0055086 316 0.040
transcription dna templated GO:0006351 377 0.040
reactive oxygen species metabolic process GO:0072593 37 0.040
cellular protein localization GO:0034613 122 0.039
regulation of cellular component movement GO:0051270 150 0.039
regulation of catalytic activity GO:0050790 304 0.039
behavior GO:0007610 205 0.038
regulation of cellular protein metabolic process GO:0032268 267 0.038
rhythmic process GO:0048511 156 0.038
protein localization GO:0008104 191 0.038
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.038
multi organism reproductive process GO:0044703 262 0.038
regulation of molecular function GO:0065009 398 0.037
response to extracellular stimulus GO:0009991 380 0.037
cellular response to acid chemical GO:0071229 75 0.037
single organism biosynthetic process GO:0044711 342 0.036
muscle system process GO:0003012 115 0.036
cardiac conduction GO:0061337 2 0.035
regulation of signal transduction GO:0009966 318 0.034
central nervous system development GO:0007417 311 0.034
negative regulation of metabolic process GO:0009892 331 0.034
regulation of programmed cell death GO:0043067 341 0.033
positive regulation of gene expression GO:0010628 244 0.033
cellular homeostasis GO:0019725 252 0.032
cellular amino acid metabolic process GO:0006520 107 0.032
response to vitamin GO:0033273 131 0.031
positive regulation of biosynthetic process GO:0009891 319 0.031
response to lipopolysaccharide GO:0032496 191 0.031
liver development GO:0001889 90 0.031
response to peptide GO:1901652 292 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.031
immune system process GO:0002376 204 0.031
regulation of phosphorylation GO:0042325 248 0.031
response to estradiol GO:0032355 164 0.031
response to carbohydrate GO:0009743 183 0.030
response to molecule of bacterial origin GO:0002237 194 0.030
action potential GO:0001508 54 0.029
response to other organism GO:0051707 220 0.029
cellular amine metabolic process GO:0044106 38 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
response to oxidative stress GO:0006979 186 0.029
multicellular organism reproduction GO:0032504 233 0.029
regulation of cell migration GO:0030334 128 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.028
regulation of apoptotic process GO:0042981 335 0.028
transmembrane transport GO:0055085 412 0.028
multicellular organismal signaling GO:0035637 44 0.028
organophosphate metabolic process GO:0019637 370 0.028
macromolecule localization GO:0033036 252 0.028
regulation of cellular component organization GO:0051128 368 0.028
macromolecular complex subunit organization GO:0043933 339 0.028
carbohydrate metabolic process GO:0005975 130 0.028
positive regulation of nervous system development GO:0051962 178 0.028
purine containing compound metabolic process GO:0072521 253 0.027
oxoacid metabolic process GO:0043436 290 0.027
regulation of g0 to g1 transition GO:0070316 3 0.027
response to peptide hormone GO:0043434 278 0.027
response to ethanol GO:0045471 162 0.027
multicellular organismal reproductive process GO:0048609 233 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
cellular response to growth factor stimulus GO:0071363 162 0.026
regulation of membrane potential GO:0042391 110 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
positive regulation of cell differentiation GO:0045597 217 0.026
organ regeneration GO:0031100 101 0.026
amine metabolic process GO:0009308 38 0.026
cellular response to stress GO:0033554 269 0.026
regulation of protein phosphorylation GO:0001932 183 0.026
response to hypoxia GO:0001666 231 0.026
cell communication involved in cardiac conduction GO:0086065 2 0.025
negative regulation of cellular biosynthetic process GO:0031327 161 0.025
developmental process involved in reproduction GO:0003006 159 0.025
cellular catabolic process GO:0044248 295 0.024
ossification GO:0001503 70 0.024
positive regulation of cellular component organization GO:0051130 200 0.024
tissue development GO:0009888 252 0.024
cellular component movement GO:0006928 248 0.024
response to bacterium GO:0009617 200 0.024
neurological system process GO:0050877 219 0.023
circulatory system process GO:0003013 183 0.023
regulation of neurogenesis GO:0050767 247 0.023
carboxylic acid metabolic process GO:0019752 289 0.023
single organism organelle organization GO:1902589 180 0.023
programmed cell death GO:0012501 392 0.023
negative regulation of developmental process GO:0051093 125 0.023
cellular ketone metabolic process GO:0042180 51 0.023
protein complex biogenesis GO:0070271 263 0.023
positive regulation of phosphorylation GO:0042327 177 0.022
regulation of nucleic acid templated transcription GO:1903506 380 0.022
response to purine containing compound GO:0014074 126 0.022
regulation of stem cell differentiation GO:2000736 2 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.022
regulation of system process GO:0044057 208 0.022
cellular response to peptide GO:1901653 133 0.022
organelle organization GO:0006996 266 0.022
single organism reproductive process GO:0044702 297 0.022
regulation of transcription dna templated GO:0006355 374 0.021
regulation of protein modification process GO:0031399 194 0.021
brain development GO:0007420 247 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.021
cell cell signaling GO:0007267 335 0.021
response to radiation GO:0009314 137 0.021
nucleic acid templated transcription GO:0097659 379 0.021
regulation of phagocytosis engulfment GO:0060099 4 0.021
cation transport GO:0006812 382 0.021
anatomical structure morphogenesis GO:0009653 298 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
synaptic transmission GO:0007268 235 0.021
positive regulation of cell projection organization GO:0031346 111 0.021
regulation of muscle system process GO:0090257 79 0.021
regulation of cell motility GO:2000145 131 0.020
muscle structure development GO:0061061 87 0.020
cellular response to alcohol GO:0097306 87 0.020
cellular chemical homeostasis GO:0055082 247 0.020
negative regulation of gene expression GO:0010629 199 0.019
organic acid metabolic process GO:0006082 292 0.019
transmission of nerve impulse GO:0019226 42 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
gastrulation GO:0007369 2 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
neuron differentiation GO:0030182 368 0.019
reproductive system development GO:0061458 128 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
positive regulation of cell migration GO:0030335 96 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
reproductive structure development GO:0048608 128 0.018
cell projection organization GO:0030030 302 0.018
response to fatty acid GO:0070542 65 0.018
response to glucose GO:0009749 136 0.018
negative regulation of cell death GO:0060548 229 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
cardiovascular system development GO:0072358 134 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
regulation of nervous system development GO:0051960 264 0.018
development of primary sexual characteristics GO:0045137 107 0.018
neuron projection development GO:0031175 273 0.018
regulation of multicellular organismal development GO:2000026 376 0.017
nucleotide biosynthetic process GO:0009165 98 0.017
positive regulation of locomotion GO:0040017 102 0.017
kidney development GO:0001822 67 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
regulation of canonical wnt signaling pathway GO:0060828 4 0.017
cellular response to corticosteroid stimulus GO:0071384 69 0.017
response to hydrogen peroxide GO:0042542 89 0.017
camp metabolic process GO:0046058 63 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
positive regulation of cell death GO:0010942 184 0.017
cellular macromolecule localization GO:0070727 122 0.017
reproduction GO:0000003 245 0.017
neuron development GO:0048666 286 0.017
cellular response to cytokine stimulus GO:0071345 127 0.016
male sex differentiation GO:0046661 64 0.016
response to tumor necrosis factor GO:0034612 56 0.016
nucleoside phosphate biosynthetic process GO:1901293 102 0.016
negative regulation of transport GO:0051051 136 0.016
cyclic nucleotide biosynthetic process GO:0009190 63 0.016
ras protein signal transduction GO:0007265 29 0.016
actin filament based process GO:0030029 86 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
regulation of kinase activity GO:0043549 117 0.016
chemical homeostasis GO:0048878 292 0.016
establishment of protein localization GO:0045184 141 0.016
response to external biotic stimulus GO:0043207 221 0.016
regulation of transferase activity GO:0051338 123 0.016
neuronal action potential GO:0019228 35 0.016
rna metabolic process GO:0016070 406 0.016
regulation of rna biosynthetic process GO:2001141 381 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
regulation of locomotion GO:0040012 148 0.015
metal ion homeostasis GO:0055065 186 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
head development GO:0060322 247 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
protein phosphorylation GO:0006468 345 0.015
response to hexose GO:0009746 144 0.015
secretion by cell GO:0032940 248 0.015
response to dexamethasone GO:0071548 49 0.015
single organism catabolic process GO:0044712 283 0.015
muscle contraction GO:0006936 88 0.015
protein oligomerization GO:0051259 191 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.014
glial cell differentiation GO:0010001 65 0.014
response to activity GO:0014823 73 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
sex differentiation GO:0007548 113 0.014
organic substance catabolic process GO:1901575 316 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
regulation of blood pressure GO:0008217 83 0.014
purine ribonucleotide biosynthetic process GO:0009152 81 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
positive regulation of signal transduction GO:0009967 175 0.014
negative regulation of molecular function GO:0044092 133 0.014
hepaticobiliary system development GO:0061008 90 0.014
response to camp GO:0051591 91 0.014
cyclic nucleotide metabolic process GO:0009187 80 0.014
positive regulation of immune system process GO:0002684 90 0.014
positive regulation of molecular function GO:0044093 230 0.014
neuron death GO:0070997 127 0.014
regeneration GO:0031099 163 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.013
protein complex assembly GO:0006461 263 0.013
exogenous drug catabolic process GO:0042738 1 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
formation of primary germ layer GO:0001704 1 0.013
response to monosaccharide GO:0034284 159 0.013
regulation of cellular localization GO:0060341 263 0.013
regulation of immune system process GO:0002682 123 0.013
gonad development GO:0008406 104 0.013
skeletal system development GO:0001501 41 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
metal ion transport GO:0030001 289 0.013
positive regulation of cell communication GO:0010647 271 0.013
cellular response to glucocorticoid stimulus GO:0071385 68 0.013
protein transport GO:0015031 132 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
carbohydrate homeostasis GO:0033500 75 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
cellular response to interleukin 1 GO:0071347 37 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
gland development GO:0048732 155 0.012
female pregnancy GO:0007565 122 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
single organism intracellular transport GO:1902582 166 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.012
regulation of response to stress GO:0080134 126 0.012
response to biotic stimulus GO:0009607 226 0.012
cyclic purine nucleotide metabolic process GO:0052652 62 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
wound healing GO:0042060 122 0.012
cognition GO:0050890 92 0.012
renal system development GO:0072001 67 0.012
mesoderm development GO:0007498 2 0.012
extracellular structure organization GO:0043062 13 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
sensory perception GO:0007600 101 0.011
cellular response to ketone GO:1901655 51 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
cellular response to tumor necrosis factor GO:0071356 46 0.011
response to glucocorticoid GO:0051384 223 0.011
regulation of organ formation GO:0003156 2 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
single organism cellular localization GO:1902580 102 0.011
regulation of protein kinase activity GO:0045859 105 0.011
learning or memory GO:0007611 90 0.011
gamete generation GO:0007276 124 0.011
ion transmembrane transport GO:0034220 365 0.011
positive regulation of response to external stimulus GO:0032103 51 0.011
circadian rhythm GO:0007623 88 0.011
aging GO:0007568 241 0.011
cytoplasmic transport GO:0016482 115 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
circulatory system development GO:0072359 134 0.011
innate immune response GO:0045087 35 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
regulation of defense response GO:0031347 68 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
secretion GO:0046903 307 0.011
regulation of muscle contraction GO:0006937 53 0.010
membrane repolarization GO:0086009 1 0.010
actin cytoskeleton organization GO:0030036 73 0.010
ribose phosphate biosynthetic process GO:0046390 87 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
glucose homeostasis GO:0042593 75 0.010
cellular response to external stimulus GO:0071496 118 0.010
proteolysis GO:0006508 175 0.010
negative regulation of osteoblast differentiation GO:0045668 2 0.010
response to retinoic acid GO:0032526 63 0.010
spermatogenesis GO:0007283 99 0.010
mapk cascade GO:0000165 140 0.010

Adamtsl4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
musculoskeletal system disease DOID:17 0 0.043
nervous system disease DOID:863 0 0.027
myopathy DOID:423 0 0.016
muscular disease DOID:0080000 0 0.016
muscular dystrophy DOID:9884 0 0.016
muscle tissue disease DOID:66 0 0.016
sensory system disease DOID:0050155 0 0.016
central nervous system disease DOID:331 0 0.015
cardiovascular system disease DOID:1287 0 0.014
retinal disease DOID:5679 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013