Rattus norvegicus

0 known processes

Adamtsl5

ADAMTS-like 5

(Aliases: Thsd6)

Adamtsl5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cell differentiation GO:0045595 320 0.057
transcription dna templated GO:0006351 377 0.057
rna metabolic process GO:0016070 406 0.056
response to inorganic substance GO:0010035 377 0.052
regulation of cellular component organization GO:0051128 368 0.050
regulation of multicellular organismal development GO:2000026 376 0.049
organelle organization GO:0006996 266 0.047
regulation of rna metabolic process GO:0051252 391 0.047
cellular component assembly GO:0022607 360 0.046
intracellular signal transduction GO:0035556 314 0.045
regulation of phosphorus metabolic process GO:0051174 349 0.044
regulation of rna biosynthetic process GO:2001141 381 0.041
cellular component biogenesis GO:0044085 368 0.041
locomotion GO:0040011 237 0.041
amine metabolic process GO:0009308 38 0.040
rna biosynthetic process GO:0032774 380 0.040
neuron differentiation GO:0030182 368 0.038
anatomical structure morphogenesis GO:0009653 298 0.038
transmembrane transport GO:0055085 412 0.038
positive regulation of phosphorus metabolic process GO:0010562 262 0.037
positive regulation of developmental process GO:0051094 283 0.037
multicellular organismal reproductive process GO:0048609 233 0.036
protein complex assembly GO:0006461 263 0.036
regulation of cell development GO:0060284 263 0.036
nucleic acid templated transcription GO:0097659 379 0.034
positive regulation of multicellular organismal process GO:0051240 387 0.034
regulation of nervous system development GO:0051960 264 0.033
negative regulation of multicellular organismal process GO:0051241 203 0.033
regulation of intracellular signal transduction GO:1902531 218 0.032
response to nutrient GO:0007584 248 0.032
cellular component movement GO:0006928 248 0.031
regulation of neurogenesis GO:0050767 247 0.031
regulation of cell proliferation GO:0042127 359 0.031
protein localization GO:0008104 191 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.031
circulatory system development GO:0072359 134 0.031
protein complex subunit organization GO:0071822 302 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
response to nutrient levels GO:0031667 370 0.030
regulation of protein metabolic process GO:0051246 289 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
protein phosphorylation GO:0006468 345 0.029
ion transmembrane transport GO:0034220 365 0.029
positive regulation of response to stimulus GO:0048584 285 0.029
single organism biosynthetic process GO:0044711 342 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
regulation of molecular function GO:0065009 398 0.029
negative regulation of cellular metabolic process GO:0031324 281 0.029
regulation of protein phosphorylation GO:0001932 183 0.029
positive regulation of cell proliferation GO:0008284 249 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.028
organic acid metabolic process GO:0006082 292 0.028
brain development GO:0007420 247 0.028
secretion GO:0046903 307 0.028
positive regulation of cell development GO:0010720 176 0.028
negative regulation of metabolic process GO:0009892 331 0.028
single organism reproductive process GO:0044702 297 0.027
cellular metal ion homeostasis GO:0006875 172 0.027
regulation of neuron differentiation GO:0045664 208 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
positive regulation of signal transduction GO:0009967 175 0.027
regulation of secretion GO:0051046 224 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
response to oxidative stress GO:0006979 186 0.026
cellular catabolic process GO:0044248 295 0.026
regulation of catalytic activity GO:0050790 304 0.026
neuron development GO:0048666 286 0.026
cellular amine metabolic process GO:0044106 38 0.026
regulation of phosphorylation GO:0042325 248 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.025
regulation of signal transduction GO:0009966 318 0.025
growth GO:0040007 165 0.025
positive regulation of cell communication GO:0010647 271 0.025
response to hydrogen peroxide GO:0042542 89 0.025
reproduction GO:0000003 245 0.024
neuron projection development GO:0031175 273 0.024
positive regulation of cellular component organization GO:0051130 200 0.023
nucleotide metabolic process GO:0009117 279 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.023
catabolic process GO:0009056 351 0.023
positive regulation of nervous system development GO:0051962 178 0.023
apoptotic process GO:0006915 381 0.023
purine containing compound metabolic process GO:0072521 253 0.023
positive regulation of neurogenesis GO:0050769 165 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.022
circulatory system process GO:0003013 183 0.022
macromolecular complex assembly GO:0065003 273 0.022
regulation of transcription dna templated GO:0006355 374 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
multicellular organism reproduction GO:0032504 233 0.022
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
regulation of cell motility GO:2000145 131 0.022
response to reactive oxygen species GO:0000302 120 0.021
single organism intracellular transport GO:1902582 166 0.021
ion homeostasis GO:0050801 212 0.021
regulation of neuron projection development GO:0010975 161 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
response to estrogen GO:0043627 232 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
heart morphogenesis GO:0003007 3 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
ras protein signal transduction GO:0007265 29 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
multi organism reproductive process GO:0044703 262 0.020
response to metal ion GO:0010038 253 0.020
central nervous system development GO:0007417 311 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
positive regulation of signaling GO:0023056 270 0.020
homeostatic process GO:0042592 331 0.020
regulation of cell projection organization GO:0031344 175 0.020
bmp signaling pathway GO:0030509 4 0.020
regulation of protein modification process GO:0031399 194 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
cellular homeostasis GO:0019725 252 0.020
secretion by cell GO:0032940 248 0.020
negative regulation of developmental process GO:0051093 125 0.019
tissue development GO:0009888 252 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
programmed cell death GO:0012501 392 0.019
cell projection organization GO:0030030 302 0.019
macromolecule localization GO:0033036 252 0.019
oxoacid metabolic process GO:0043436 290 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
localization of cell GO:0051674 202 0.019
response to biotic stimulus GO:0009607 226 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
defense response GO:0006952 194 0.019
regulation of kinase activity GO:0043549 117 0.019
carboxylic acid metabolic process GO:0019752 289 0.019
response to extracellular stimulus GO:0009991 380 0.019
sodium ion transport GO:0006814 82 0.019
cellular response to endogenous stimulus GO:0071495 377 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
negative regulation of cell communication GO:0010648 158 0.018
positive regulation of protein modification process GO:0031401 142 0.018
response to ethanol GO:0045471 162 0.018
positive regulation of gene expression GO:0010628 244 0.018
response to wounding GO:0009611 254 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
negative regulation of response to stimulus GO:0048585 155 0.017
metal ion homeostasis GO:0055065 186 0.017
intracellular transport GO:0046907 185 0.017
positive regulation of molecular function GO:0044093 230 0.017
regulation of cellular component movement GO:0051270 150 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
response to other organism GO:0051707 220 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
cellular ketone metabolic process GO:0042180 51 0.017
purine nucleotide biosynthetic process GO:0006164 83 0.017
cell motility GO:0048870 202 0.017
cellular cation homeostasis GO:0030003 180 0.017
calcium ion homeostasis GO:0055074 162 0.017
embryonic appendage morphogenesis GO:0035113 4 0.017
female pregnancy GO:0007565 122 0.017
developmental process involved in reproduction GO:0003006 159 0.016
negative regulation of cell death GO:0060548 229 0.016
transcription from rna polymerase ii promoter GO:0006366 252 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
regulation of locomotion GO:0040012 148 0.016
reproductive process GO:0022414 372 0.016
regulation of homeostatic process GO:0032844 101 0.016
protein complex biogenesis GO:0070271 263 0.016
regulation of stem cell differentiation GO:2000736 2 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
vesicle mediated transport GO:0016192 181 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
cellular response to stress GO:0033554 269 0.016
cellular response to lipid GO:0071396 201 0.016
hematopoietic progenitor cell differentiation GO:0002244 2 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
response to oxygen levels GO:0070482 265 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
cellular ion homeostasis GO:0006873 184 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
second messenger mediated signaling GO:0019932 51 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.015
reactive oxygen species metabolic process GO:0072593 37 0.015
metal ion transport GO:0030001 289 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
positive regulation of transport GO:0051050 245 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
cardiovascular system development GO:0072358 134 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
appendage morphogenesis GO:0035107 4 0.015
sensory perception GO:0007600 101 0.015
regulation of mapk cascade GO:0043408 116 0.015
behavior GO:0007610 205 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
sequestering of calcium ion GO:0051208 8 0.015
dephosphorylation GO:0016311 98 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
cellular protein localization GO:0034613 122 0.015
cellular component morphogenesis GO:0032989 155 0.015
regulation of cellular component biogenesis GO:0044087 86 0.015
signal transduction by phosphorylation GO:0023014 144 0.014
axis specification GO:0009798 4 0.014
oxidation reduction process GO:0055114 304 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
cell activation GO:0001775 97 0.014
positive regulation of locomotion GO:0040017 102 0.014
anterior posterior pattern specification GO:0009952 1 0.014
response to peptide GO:1901652 292 0.014
neurological system process GO:0050877 219 0.014
immune system process GO:0002376 204 0.014
regulation of growth GO:0040008 105 0.014
response to growth factor GO:0070848 189 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
response to decreased oxygen levels GO:0036293 237 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
response to hypoxia GO:0001666 231 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
cation homeostasis GO:0055080 195 0.014
protein transport GO:0015031 132 0.014
chemical homeostasis GO:0048878 292 0.014
response to external biotic stimulus GO:0043207 221 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
dendrite development GO:0016358 72 0.014
sequestering of metal ion GO:0051238 9 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
regulation of cellular protein metabolic process GO:0032268 267 0.014
regulation of secretion by cell GO:1903530 208 0.014
purine containing compound biosynthetic process GO:0072522 85 0.014
organophosphate metabolic process GO:0019637 370 0.014
organonitrogen compound catabolic process GO:1901565 179 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
single organism catabolic process GO:0044712 283 0.013
protein oligomerization GO:0051259 191 0.013
sexual reproduction GO:0019953 148 0.013
nucleoside metabolic process GO:0009116 179 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
regulation of transferase activity GO:0051338 123 0.013
regulation of protein kinase activity GO:0045859 105 0.013
cation transport GO:0006812 382 0.013
response to acid chemical GO:0001101 222 0.013
maintenance of location GO:0051235 17 0.013
regulation of hydrolase activity GO:0051336 143 0.013
organic substance catabolic process GO:1901575 316 0.013
gamete generation GO:0007276 124 0.013
mapk cascade GO:0000165 140 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
multi multicellular organism process GO:0044706 138 0.013
regulation of ion transport GO:0043269 245 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
negative regulation of signaling GO:0023057 157 0.013
ossification GO:0001503 70 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
response to ketone GO:1901654 182 0.012
adult locomotory behavior GO:0008344 4 0.012
cardiac chamber development GO:0003205 1 0.012
regulation of organelle organization GO:0033043 80 0.012
purine containing compound catabolic process GO:0072523 138 0.012
cell cell signaling GO:0007267 335 0.012
purine ribonucleotide biosynthetic process GO:0009152 81 0.012
learning or memory GO:0007611 90 0.012
aging GO:0007568 241 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
positive regulation of cell motility GO:2000147 97 0.012
regeneration GO:0031099 163 0.012
cell type specific apoptotic process GO:0097285 134 0.012
response to estradiol GO:0032355 164 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
single organism organelle organization GO:1902589 180 0.012
head development GO:0060322 247 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
response to toxic substance GO:0009636 133 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
response to peptide hormone GO:0043434 278 0.012
heterocycle catabolic process GO:0046700 167 0.012
calcium ion transport GO:0006816 131 0.012
cellular chemical homeostasis GO:0055082 247 0.012
immune response GO:0006955 104 0.012
regulation of anatomical structure size GO:0090066 135 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
regulation of cell growth GO:0001558 85 0.011
cell growth GO:0016049 104 0.011
regulation of apoptotic process GO:0042981 335 0.011
negative regulation of transport GO:0051051 136 0.011
heart development GO:0007507 72 0.011
cell part morphogenesis GO:0032990 123 0.011
rho protein signal transduction GO:0007266 11 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
regulation of synaptic transmission GO:0050804 141 0.011
amide transport GO:0042886 105 0.011
positive regulation of cell migration GO:0030335 96 0.011
muscle system process GO:0003012 115 0.011
limb morphogenesis GO:0035108 4 0.011
regulation of cell migration GO:0030334 128 0.011
lipid storage GO:0019915 1 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
nucleoside catabolic process GO:0009164 126 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
lipid metabolic process GO:0006629 283 0.011
regulation of embryonic development GO:0045995 2 0.011
sensory organ development GO:0007423 74 0.011
negative regulation of cell development GO:0010721 82 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
mitochondrion organization GO:0007005 35 0.011
regulation of immune system process GO:0002682 123 0.011
exocytosis GO:0006887 60 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
blood circulation GO:0008015 183 0.011
meiotic cell cycle process GO:1903046 3 0.011
response to calcium ion GO:0051592 59 0.011
embryonic limb morphogenesis GO:0030326 4 0.011
regulation of system process GO:0044057 208 0.011
neuron fate commitment GO:0048663 4 0.011
dna metabolic process GO:0006259 96 0.011
male gamete generation GO:0048232 99 0.011
gliogenesis GO:0042063 93 0.011
regulation of cellular localization GO:0060341 263 0.011
response to bacterium GO:0009617 200 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
response to transition metal nanoparticle GO:1990267 122 0.010
embryonic skeletal system morphogenesis GO:0048704 3 0.010
monocarboxylic acid metabolic process GO:0032787 152 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
cation transmembrane transport GO:0098655 263 0.010
establishment of protein localization GO:0045184 141 0.010
cellular response to nitrogen compound GO:1901699 210 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
response to vitamin GO:0033273 131 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
protein homooligomerization GO:0051260 91 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.010
morphogenesis of a polarized epithelium GO:0001738 1 0.010
aromatic compound catabolic process GO:0019439 168 0.010
negative regulation of gene expression GO:0010629 199 0.010
regulation of vesicle mediated transport GO:0060627 81 0.010

Adamtsl5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
musculoskeletal system disease DOID:17 0 0.045
nervous system disease DOID:863 0 0.044
sensory system disease DOID:0050155 0 0.025
muscular disease DOID:0080000 0 0.022
muscle tissue disease DOID:66 0 0.022
eye and adnexa disease DOID:1492 0 0.021
eye disease DOID:5614 0 0.015
bone disease DOID:0080001 0 0.015
connective tissue disease DOID:65 0 0.015
myopathy DOID:423 0 0.014
muscular dystrophy DOID:9884 0 0.014
disease of metabolism DOID:0014667 0 0.010