Rattus norvegicus

0 known processes

Eps8

epidermal growth factor receptor pathway substrate 8

Eps8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.120
apoptotic process GO:0006915 381 0.098
neuron development GO:0048666 286 0.093
cell projection organization GO:0030030 302 0.065
neuron differentiation GO:0030182 368 0.057
neuron projection development GO:0031175 273 0.056
regulation of nervous system development GO:0051960 264 0.056
positive regulation of phosphorus metabolic process GO:0010562 262 0.056
positive regulation of response to stimulus GO:0048584 285 0.055
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.055
rna metabolic process GO:0016070 406 0.054
regulation of rna biosynthetic process GO:2001141 381 0.053
positive regulation of signaling GO:0023056 270 0.052
transcription dna templated GO:0006351 377 0.048
regulation of molecular function GO:0065009 398 0.045
response to oxygen levels GO:0070482 265 0.045
positive regulation of apoptotic process GO:0043065 154 0.043
central nervous system development GO:0007417 311 0.042
cardiovascular system development GO:0072358 134 0.041
response to extracellular stimulus GO:0009991 380 0.041
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.039
ion transmembrane transport GO:0034220 365 0.039
nucleic acid templated transcription GO:0097659 379 0.039
metanephric comma shaped body morphogenesis GO:0072278 2 0.038
regulation of multicellular organismal development GO:2000026 376 0.038
regulation of cell development GO:0060284 263 0.038
regulation of rna metabolic process GO:0051252 391 0.037
regulation of cell proliferation GO:0042127 359 0.036
regulation of cell differentiation GO:0045595 320 0.035
secretion by cell GO:0032940 248 0.035
regulation of apoptotic process GO:0042981 335 0.034
ras protein signal transduction GO:0007265 29 0.033
eye morphogenesis GO:0048592 4 0.033
regulation of signal transduction GO:0009966 318 0.033
positive regulation of cell proliferation GO:0008284 249 0.032
reproductive process GO:0022414 372 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.031
aging GO:0007568 241 0.031
ossification GO:0001503 70 0.030
regulation of phosphorus metabolic process GO:0051174 349 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
negative regulation of metabolic process GO:0009892 331 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
programmed cell death GO:0012501 392 0.029
regulation of phosphate metabolic process GO:0019220 349 0.028
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.028
regulation of catalytic activity GO:0050790 304 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
positive regulation of cell development GO:0010720 176 0.026
regulation of intracellular signal transduction GO:1902531 218 0.026
ribonucleotide biosynthetic process GO:0009260 85 0.026
camp metabolic process GO:0046058 63 0.026
inflammatory response GO:0006954 150 0.026
action potential GO:0001508 54 0.026
negative regulation of rna biosynthetic process GO:1902679 118 0.026
vesicle mediated transport GO:0016192 181 0.026
positive regulation of molecular function GO:0044093 230 0.025
urogenital system development GO:0001655 78 0.025
negative regulation of gene expression GO:0010629 199 0.025
rhythmic process GO:0048511 156 0.025
regulation of transcription dna templated GO:0006355 374 0.024
cellular component assembly GO:0022607 360 0.024
insulin like growth factor receptor signaling pathway GO:0048009 3 0.024
respiratory system process GO:0003016 3 0.024
single organism reproductive process GO:0044702 297 0.024
macromolecule localization GO:0033036 252 0.024
transmembrane transport GO:0055085 412 0.024
cellular macromolecule localization GO:0070727 122 0.023
negative regulation of apoptotic process GO:0043066 181 0.023
respiratory gaseous exchange GO:0007585 4 0.023
regulation of vasculature development GO:1901342 44 0.023
positive regulation of signal transduction GO:0009967 175 0.023
brain development GO:0007420 247 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
intracellular signal transduction GO:0035556 314 0.022
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.022
inorganic ion transmembrane transport GO:0098660 229 0.022
blood vessel morphogenesis GO:0048514 58 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
anatomical structure formation involved in morphogenesis GO:0048646 83 0.021
retina morphogenesis in camera type eye GO:0060042 1 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
camera type eye morphogenesis GO:0048593 2 0.021
urinary bladder smooth muscle contraction GO:0014832 4 0.021
regulation of anatomical structure morphogenesis GO:0022603 141 0.021
negative regulation of rna metabolic process GO:0051253 123 0.021
organ morphogenesis GO:0009887 75 0.021
proteolysis GO:0006508 175 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
cation homeostasis GO:0055080 195 0.021
regulation of behavior GO:0050795 61 0.021
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
positive regulation of cell communication GO:0010647 271 0.020
purine nucleotide biosynthetic process GO:0006164 83 0.020
homeostatic process GO:0042592 331 0.020
neurotransmitter gated ion channel clustering GO:0072578 3 0.020
small gtpase mediated signal transduction GO:0007264 36 0.020
cation transmembrane transport GO:0098655 263 0.019
transcription from rna polymerase ii promoter GO:0006366 252 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
negative regulation of signaling GO:0023057 157 0.019
anterior posterior pattern specification GO:0009952 1 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
rna biosynthetic process GO:0032774 380 0.019
response to corticosteroid GO:0031960 235 0.019
single organism organelle organization GO:1902589 180 0.019
cation transport GO:0006812 382 0.019
reproduction GO:0000003 245 0.019
signal transduction by phosphorylation GO:0023014 144 0.019
regulation of map kinase activity GO:0043405 53 0.019
dna metabolic process GO:0006259 96 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
cellular response to stress GO:0033554 269 0.018
regulation of neurogenesis GO:0050767 247 0.018
n methyl d aspartate receptor clustering GO:0097114 2 0.018
regeneration GO:0031099 163 0.018
response to decreased oxygen levels GO:0036293 237 0.018
motor neuron axon guidance GO:0008045 1 0.018
organ regeneration GO:0031100 101 0.018
multicellular organism reproduction GO:0032504 233 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
purine containing compound biosynthetic process GO:0072522 85 0.018
regulation of synaptic transmission GO:0050804 141 0.017
salivary gland morphogenesis GO:0007435 1 0.017
protein phosphorylation GO:0006468 345 0.017
negative regulation of cell death GO:0060548 229 0.017
positive regulation of developmental process GO:0051094 283 0.017
organic substance catabolic process GO:1901575 316 0.017
renin secretion into blood stream GO:0002001 1 0.017
kidney development GO:0001822 67 0.017
regulation of cellular component organization GO:0051128 368 0.017
regulation of secretion GO:0051046 224 0.017
head development GO:0060322 247 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
single organism biosynthetic process GO:0044711 342 0.017
energy reserve metabolic process GO:0006112 25 0.016
purine ribonucleotide biosynthetic process GO:0009152 81 0.016
blood vessel development GO:0001568 69 0.016
axis specification GO:0009798 4 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
response to nutrient levels GO:0031667 370 0.016
regulation of protein metabolic process GO:0051246 289 0.016
catabolic process GO:0009056 351 0.016
response to hypoxia GO:0001666 231 0.016
angiogenesis GO:0001525 53 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
circulatory system development GO:0072359 134 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
positive regulation of nervous system development GO:0051962 178 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
cell cell signaling GO:0007267 335 0.015
Fly
purine ribonucleotide metabolic process GO:0009150 227 0.015
heterocycle catabolic process GO:0046700 167 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
gastrulation GO:0007369 2 0.015
spermatogenesis GO:0007283 99 0.015
cellular component biogenesis GO:0044085 368 0.015
regulation of cell migration GO:0030334 128 0.014
regulation of neuron differentiation GO:0045664 208 0.014
regulation of programmed cell death GO:0043067 341 0.014
gamete generation GO:0007276 124 0.014
negative regulation of intracellular estrogen receptor signaling pathway GO:0033147 2 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
cellular homeostasis GO:0019725 252 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
generation of precursor metabolites and energy GO:0006091 62 0.014
negative regulation of cell communication GO:0010648 158 0.014
regulation of protein serine threonine kinase activity GO:0071900 64 0.014
urinary tract smooth muscle contraction GO:0014848 4 0.014
platelet aggregation GO:0070527 4 0.014
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.014
protein localization GO:0008104 191 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
response to ammonium ion GO:0060359 71 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
response to electrical stimulus GO:0051602 56 0.013
metal ion transport GO:0030001 289 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
response to growth factor GO:0070848 189 0.013
glucan metabolic process GO:0044042 23 0.013
response to light stimulus GO:0009416 52 0.013
response to peptide GO:1901652 292 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
ribose phosphate biosynthetic process GO:0046390 87 0.013
regulation of kinase activity GO:0043549 117 0.013
response to glucose GO:0009749 136 0.013
behavior GO:0007610 205 0.013
Fly
organophosphate biosynthetic process GO:0090407 143 0.013
single organism behavior GO:0044708 130 0.013
Fly
positive regulation of gene expression GO:0010628 244 0.013
defense response GO:0006952 194 0.013
cyclic nucleotide biosynthetic process GO:0009190 63 0.013
regulation of cellular localization GO:0060341 263 0.012
muscle structure development GO:0061061 87 0.012
intracellular transport GO:0046907 185 0.012
regulation of mapk cascade GO:0043408 116 0.012
cyclic purine nucleotide metabolic process GO:0052652 62 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
chemical homeostasis GO:0048878 292 0.012
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241 2 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
embryo development GO:0009790 49 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
divalent inorganic cation transport GO:0072511 134 0.012
sexual reproduction GO:0019953 148 0.012
cellular response to lipid GO:0071396 201 0.012
cellular chemical homeostasis GO:0055082 247 0.012
adult locomotory behavior GO:0008344 4 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
ribonucleoside monophosphate metabolic process GO:0009161 88 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
organelle organization GO:0006996 266 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
tissue regeneration GO:0042246 36 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
organelle localization GO:0051640 55 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
regulation of transmembrane transporter activity GO:0022898 49 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
embryonic pattern specification GO:0009880 1 0.011
synaptic transmission glutamatergic GO:0035249 33 0.011
cell adhesion GO:0007155 110 0.011
response to bacterium GO:0009617 200 0.011
cellular polysaccharide metabolic process GO:0044264 23 0.011
regulation of endocrine process GO:0044060 21 0.011
taxis GO:0042330 67 0.011
sensory perception of pain GO:0019233 73 0.011
regulation of respiratory system process GO:0044065 1 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
regulation of cell projection organization GO:0031344 175 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
positive regulation of cell death GO:0010942 184 0.011
male gamete generation GO:0048232 99 0.011
calcium ion transport GO:0006816 131 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
protein transport GO:0015031 132 0.011
positive regulation of long term synaptic potentiation GO:1900273 4 0.011
membrane organization GO:0061024 94 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
regulation of cellular component movement GO:0051270 150 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
cgmp biosynthetic process GO:0006182 15 0.011
salivary gland development GO:0007431 3 0.011
organophosphate metabolic process GO:0019637 370 0.011
establishment of protein localization GO:0045184 141 0.011
gonad development GO:0008406 104 0.011
negative regulation of developmental process GO:0051093 125 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
nitrogen compound transport GO:0071705 229 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
involuntary skeletal muscle contraction GO:0003011 2 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
neuron projection regeneration GO:0031102 35 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.010
calcium ion transmembrane transport GO:0070588 70 0.010
cellular response to nitrogen compound GO:1901699 210 0.010
regulation of membrane potential GO:0042391 110 0.010
rna localization GO:0006403 4 0.010
calcium ion homeostasis GO:0055074 162 0.010
protein complex subunit organization GO:0071822 302 0.010
growth GO:0040007 165 0.010
multicellular organismal signaling GO:0035637 44 0.010
mapk cascade GO:0000165 140 0.010
negative regulation of signal transduction GO:0009968 83 0.010
positive regulation of saliva secretion GO:0046878 3 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
multi multicellular organism process GO:0044706 138 0.010
negative regulation of cell development GO:0010721 82 0.010
response to glucocorticoid GO:0051384 223 0.010

Eps8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
sensory system disease DOID:0050155 0 0.020
eye and adnexa disease DOID:1492 0 0.010