Rattus norvegicus

138 known processes

Mecp2

methyl CpG binding protein 2

Mecp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.153
rna biosynthetic process GO:0032774 380 0.082
negative regulation of macromolecule metabolic process GO:0010605 260 0.074
regulation of transcription dna templated GO:0006355 374 0.066
negative regulation of metabolic process GO:0009892 331 0.065
neuron development GO:0048666 286 0.062
cellular response to cytokine stimulus GO:0071345 127 0.062
regulation of cellular component organization GO:0051128 368 0.057
negative regulation of gene expression GO:0010629 199 0.055
cellular response to lipid GO:0071396 201 0.055
negative regulation of cellular biosynthetic process GO:0031327 161 0.054
central nervous system development GO:0007417 311 0.054
cellular homeostasis GO:0019725 252 0.052
regulation of apoptotic process GO:0042981 335 0.051
negative regulation of cellular metabolic process GO:0031324 281 0.050
apoptotic process GO:0006915 381 0.049
homeostatic process GO:0042592 331 0.048
protein heterooligomerization GO:0051291 89 0.048
single organism reproductive process GO:0044702 297 0.047
brain development GO:0007420 247 0.047
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.047
regulation of programmed cell death GO:0043067 341 0.047
g protein coupled receptor signaling pathway GO:0007186 242 0.046
adult locomotory behavior GO:0008344 4 0.046
response to cytokine GO:0034097 215 0.046
single organism biosynthetic process GO:0044711 342 0.043
response to metal ion GO:0010038 253 0.043
negative regulation of cell proliferation GO:0008285 119 0.043
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.042
response to vitamin GO:0033273 131 0.042
regulation of molecular function GO:0065009 398 0.042
regulation of response to external stimulus GO:0032101 106 0.042
neurological system process GO:0050877 219 0.041
cell morphogenesis GO:0000902 142 0.040
regulation of catalytic activity GO:0050790 304 0.040
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.040
cellular component biogenesis GO:0044085 368 0.040
cellular ion homeostasis GO:0006873 184 0.040
negative regulation of cell development GO:0010721 82 0.039
regulation of phosphorylation GO:0042325 248 0.039
cellular response to oxygen containing compound GO:1901701 386 0.039
head development GO:0060322 247 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
positive regulation of gene expression GO:0010628 244 0.038
response to hypoxia GO:0001666 231 0.038
negative regulation of multicellular organismal process GO:0051241 203 0.037
response to oxidative stress GO:0006979 186 0.036
hormone transport GO:0009914 121 0.035
nucleic acid templated transcription GO:0097659 379 0.035
response to other organism GO:0051707 220 0.034
immune system process GO:0002376 204 0.033
carboxylic acid metabolic process GO:0019752 289 0.032
positive regulation of cell proliferation GO:0008284 249 0.032
regulation of cell differentiation GO:0045595 320 0.032
response to wounding GO:0009611 254 0.032
response to organophosphorus GO:0046683 102 0.032
transcription from rna polymerase ii promoter GO:0006366 252 0.031
tissue development GO:0009888 252 0.031
gland development GO:0048732 155 0.031
renal system development GO:0072001 67 0.031
response to growth factor GO:0070848 189 0.031
negative regulation of transcription dna templated GO:0045892 116 0.031
secretion by cell GO:0032940 248 0.030
negative regulation of nucleic acid templated transcription GO:1903507 117 0.030
lipid metabolic process GO:0006629 283 0.030
cell morphogenesis involved in differentiation GO:0000904 119 0.030
negative regulation of cell differentiation GO:0045596 99 0.030
regulation of secretion by cell GO:1903530 208 0.029
response to inorganic substance GO:0010035 377 0.029
regulation of vesicle mediated transport GO:0060627 81 0.029
programmed cell death GO:0012501 392 0.029
cytokine mediated signaling pathway GO:0019221 43 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
regulation of protein metabolic process GO:0051246 289 0.028
cellular response to growth factor stimulus GO:0071363 162 0.028
cellular component morphogenesis GO:0032989 155 0.028
regulation of ion transport GO:0043269 245 0.028
regulation of cell activation GO:0050865 50 0.027
cellular component assembly GO:0022607 360 0.027
regulation of system process GO:0044057 208 0.027
cellular ketone metabolic process GO:0042180 51 0.027
cell type specific apoptotic process GO:0097285 134 0.027
response to purine containing compound GO:0014074 126 0.027
metanephric comma shaped body morphogenesis GO:0072278 2 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
vesicle mediated transport GO:0016192 181 0.026
response to glucocorticoid GO:0051384 223 0.026
sensory organ development GO:0007423 74 0.026
regulation of multicellular organismal development GO:2000026 376 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.025
response to acid chemical GO:0001101 222 0.025
regeneration GO:0031099 163 0.025
cellular component movement GO:0006928 248 0.025
axon midline choice point recognition GO:0016199 2 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
secretion GO:0046903 307 0.025
positive regulation of nucleic acid templated transcription GO:1903508 197 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.025
regulation of signal transduction GO:0009966 318 0.024
regulation of neuron differentiation GO:0045664 208 0.024
axon choice point recognition GO:0016198 2 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
protein complex subunit organization GO:0071822 302 0.024
macromolecular complex assembly GO:0065003 273 0.024
positive regulation of biosynthetic process GO:0009891 319 0.023
negative regulation of molecular function GO:0044092 133 0.023
response to nutrient GO:0007584 248 0.023
cell projection organization GO:0030030 302 0.023
bmp signaling pathway GO:0030509 4 0.023
anion transport GO:0006820 178 0.022
negative regulation of phosphorus metabolic process GO:0010563 80 0.022
peptide transport GO:0015833 97 0.022
transcription dna templated GO:0006351 377 0.022
cell projection morphogenesis GO:0048858 123 0.022
axonogenesis GO:0007409 71 0.022
biological adhesion GO:0022610 110 0.022
neuron projection morphogenesis GO:0048812 122 0.022
purine containing compound metabolic process GO:0072521 253 0.022
positive regulation of hormone secretion GO:0046887 65 0.022
protein phosphorylation GO:0006468 345 0.022
rna metabolic process GO:0016070 406 0.022
response to toxic substance GO:0009636 133 0.022
cellular chemical homeostasis GO:0055082 247 0.022
organelle organization GO:0006996 266 0.021
neuron differentiation GO:0030182 368 0.021
positive regulation of secretion GO:0051047 140 0.021
negative regulation of signaling GO:0023057 157 0.021
regulation of nervous system development GO:0051960 264 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
intracellular signal transduction GO:0035556 314 0.021
nitrogen compound transport GO:0071705 229 0.021
regulation of cell proliferation GO:0042127 359 0.021
macromolecular complex subunit organization GO:0043933 339 0.020
regulation of rna metabolic process GO:0051252 391 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.020
positive regulation of molecular function GO:0044093 230 0.020
regulation of neurogenesis GO:0050767 247 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
regulation of hormone levels GO:0010817 187 0.020
s shaped body morphogenesis GO:0072050 2 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.020
response to extracellular stimulus GO:0009991 380 0.020
positive regulation of transport GO:0051050 245 0.020
cellular response to steroid hormone stimulus GO:0071383 93 0.019
protein complex assembly GO:0006461 263 0.019
neuron projection development GO:0031175 273 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
metal ion transport GO:0030001 289 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
cell part morphogenesis GO:0032990 123 0.019
amine metabolic process GO:0009308 38 0.019
nucleotide metabolic process GO:0009117 279 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
response to ketone GO:1901654 182 0.019
response to corticosteroid GO:0031960 235 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.018
dna metabolic process GO:0006259 96 0.018
regulation of secretion GO:0051046 224 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
inflammatory response GO:0006954 150 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
entrainment of circadian clock GO:0009649 3 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
axon guidance GO:0007411 24 0.018
regulation of cell morphogenesis GO:0022604 77 0.018
response to decreased oxygen levels GO:0036293 237 0.018
organic acid metabolic process GO:0006082 292 0.018
gastrulation GO:0007369 2 0.018
positive regulation of catalytic activity GO:0043085 184 0.017
positive regulation of secretion by cell GO:1903532 128 0.017
cell adhesion GO:0007155 110 0.017
response to oxygen levels GO:0070482 265 0.017
regulation of transferase activity GO:0051338 123 0.017
cell cell signaling GO:0007267 335 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
cellular cation homeostasis GO:0030003 180 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
signal release GO:0023061 145 0.017
cellular response to corticosteroid stimulus GO:0071384 69 0.017
protein complex biogenesis GO:0070271 263 0.017
negative regulation of cell communication GO:0010648 158 0.017
negative regulation of catalytic activity GO:0043086 103 0.017
metanephric s shaped body morphogenesis GO:0072284 2 0.017
response to nutrient levels GO:0031667 370 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
developmental process involved in reproduction GO:0003006 159 0.017
response to glucose GO:0009749 136 0.016
axon development GO:0061564 96 0.016
gliogenesis GO:0042063 93 0.016
organic hydroxy compound metabolic process GO:1901615 115 0.016
single organism organelle organization GO:1902589 180 0.016
proteolysis GO:0006508 175 0.016
terpenoid metabolic process GO:0006721 37 0.016
cellular catabolic process GO:0044248 295 0.016
negative regulation of phosphate metabolic process GO:0045936 80 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
ion homeostasis GO:0050801 212 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
defense response GO:0006952 194 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
regulation of purine nucleotide metabolic process GO:1900542 115 0.016
negative regulation of intracellular estrogen receptor signaling pathway GO:0033147 2 0.016
response to reactive oxygen species GO:0000302 120 0.015
eye morphogenesis GO:0048592 4 0.015
regulation of cellular localization GO:0060341 263 0.015
lipid storage GO:0019915 1 0.015
multicellular organismal signaling GO:0035637 44 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
regulation of hydrolase activity GO:0051336 143 0.015
protein oligomerization GO:0051259 191 0.015
intracellular receptor signaling pathway GO:0030522 35 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
cellular response to stress GO:0033554 269 0.015
cardiac chamber development GO:0003205 1 0.015
oxoacid metabolic process GO:0043436 290 0.015
response to tumor necrosis factor GO:0034612 56 0.015
activation of cysteine type endopeptidase activity GO:0097202 4 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
response to camp GO:0051591 91 0.015
cellular response to glucocorticoid stimulus GO:0071385 68 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
regulation of leukocyte activation GO:0002694 45 0.014
urogenital system development GO:0001655 78 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
response to external biotic stimulus GO:0043207 221 0.014
organophosphate metabolic process GO:0019637 370 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
transmembrane transport GO:0055085 412 0.014
catabolic process GO:0009056 351 0.014
growth GO:0040007 165 0.014
wound healing GO:0042060 122 0.014
regulation of peptide secretion GO:0002791 82 0.014
response to calcium ion GO:0051592 59 0.014
synaptic transmission GO:0007268 235 0.014
regulation of protein modification process GO:0031399 194 0.014
t cell homeostasis GO:0043029 2 0.014
nucleotide biosynthetic process GO:0009165 98 0.014
negative regulation of response to external stimulus GO:0032102 37 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
aging GO:0007568 241 0.014
intracellular transport GO:0046907 185 0.014
lymphocyte homeostasis GO:0002260 2 0.013
response to alkaloid GO:0043279 132 0.013
small molecule biosynthetic process GO:0044283 124 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
nucleoside metabolic process GO:0009116 179 0.013
chemotaxis GO:0006935 66 0.013
embryonic pattern specification GO:0009880 1 0.013
negative regulation of nervous system development GO:0051961 79 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
reproductive process GO:0022414 372 0.013
protein maturation GO:0051604 68 0.013
cellular response to reactive oxygen species GO:0034614 55 0.013
salivary gland development GO:0007431 3 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
positive regulation of nervous system development GO:0051962 178 0.013
regulation of response to wounding GO:1903034 69 0.013
membrane organization GO:0061024 94 0.013
positive regulation of neurogenesis GO:0050769 165 0.012
phototransduction visible light GO:0007603 2 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
response to carbohydrate GO:0009743 183 0.012
gtp catabolic process GO:0006184 71 0.012
sensory perception GO:0007600 101 0.012
protein transport GO:0015031 132 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
response to hexose GO:0009746 144 0.012
calcium ion homeostasis GO:0055074 162 0.012
cellular hormone metabolic process GO:0034754 49 0.012
skeletal system development GO:0001501 41 0.012
oxidation reduction process GO:0055114 304 0.012
regulation of neuron projection development GO:0010975 161 0.012
ion transmembrane transport GO:0034220 365 0.012
cell activation GO:0001775 97 0.012
cellular amine metabolic process GO:0044106 38 0.012
axis specification GO:0009798 4 0.012
cation transport GO:0006812 382 0.012
reproductive system development GO:0061458 128 0.012
cellular response to metal ion GO:0071248 55 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
response to axon injury GO:0048678 59 0.012
nephron tubule epithelial cell differentiation GO:0072160 1 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
camera type eye morphogenesis GO:0048593 2 0.012
chemosensory behavior GO:0007635 2 0.012
cell proliferation in external granule layer GO:0021924 1 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
response to hydrogen peroxide GO:0042542 89 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
regulation of proteolysis GO:0030162 66 0.012
cellular hyperosmotic response GO:0071474 4 0.012
peptidyl amino acid modification GO:0018193 126 0.011
response to fibroblast growth factor GO:0071774 29 0.011
apoptotic mitochondrial changes GO:0008637 10 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
taxis GO:0042330 67 0.011
regulation of nephron tubule epithelial cell differentiation GO:0072182 1 0.011
regulation of hormone secretion GO:0046883 106 0.011
positive regulation of cell death GO:0010942 184 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
asymmetric protein localization GO:0008105 2 0.011
negative regulation of cell death GO:0060548 229 0.011
response to increased oxygen levels GO:0036296 45 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
regulation of dendrite development GO:0050773 59 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
sensory perception of light stimulus GO:0050953 3 0.011
camera type eye development GO:0043010 48 0.011
metal ion homeostasis GO:0055065 186 0.011
epithelium development GO:0060429 96 0.011
anterior posterior pattern specification GO:0009952 1 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
single organism intracellular transport GO:1902582 166 0.010
peptide secretion GO:0002790 86 0.010
sexual reproduction GO:0019953 148 0.010
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
olfactory behavior GO:0042048 2 0.010
positive regulation of cellular amine metabolic process GO:0033240 3 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
regulation of inflammatory response GO:0050727 48 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
cellular amino acid metabolic process GO:0006520 107 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
lens fiber cell differentiation GO:0070306 3 0.010
response to cgmp GO:0070305 3 0.010
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.010
response to biotic stimulus GO:0009607 226 0.010

Mecp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.062
musculoskeletal system disease DOID:17 0 0.062
disease of metabolism DOID:0014667 0 0.023
connective tissue disease DOID:65 0 0.021
myopathy DOID:423 0 0.019
muscular disease DOID:0080000 0 0.019
muscle tissue disease DOID:66 0 0.019
bone disease DOID:0080001 0 0.019
bone development disease DOID:0080006 0 0.016
nervous system disease DOID:863 0 0.015