Rattus norvegicus

0 known processes

Mt3

metallothionein 3

(Aliases: GIF,Mt-3)

Mt3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cell communication GO:0010647 271 0.181
response to metal ion GO:0010038 253 0.134
central nervous system development GO:0007417 311 0.131
tissue development GO:0009888 252 0.120
response to glucocorticoid GO:0051384 223 0.112
cation transport GO:0006812 382 0.084
regulation of cell proliferation GO:0042127 359 0.083
response to inorganic substance GO:0010035 377 0.081
response to wounding GO:0009611 254 0.080
response to corticosteroid GO:0031960 235 0.073
brain development GO:0007420 247 0.070
regulation of cellular component organization GO:0051128 368 0.070
response to molecule of bacterial origin GO:0002237 194 0.070
response to oxygen levels GO:0070482 265 0.069
cellular ion homeostasis GO:0006873 184 0.066
cellular chemical homeostasis GO:0055082 247 0.065
response to hypoxia GO:0001666 231 0.063
cellular cation homeostasis GO:0030003 180 0.062
metal ion transport GO:0030001 289 0.061
ion transmembrane transport GO:0034220 365 0.060
cellular response to oxygen containing compound GO:1901701 386 0.059
ion homeostasis GO:0050801 212 0.059
homeostatic process GO:0042592 331 0.058
monovalent inorganic cation transport GO:0015672 172 0.056
regulation of system process GO:0044057 208 0.055
programmed cell death GO:0012501 392 0.051
response to transition metal nanoparticle GO:1990267 122 0.051
response to peptide hormone GO:0043434 278 0.051
apoptotic process GO:0006915 381 0.050
regulation of synaptic plasticity GO:0048167 70 0.049
divalent metal ion transport GO:0070838 132 0.049
regulation of ion transport GO:0043269 245 0.049
cellular response to lipid GO:0071396 201 0.048
defense response GO:0006952 194 0.047
head development GO:0060322 247 0.047
synaptic transmission GO:0007268 235 0.047
response to external biotic stimulus GO:0043207 221 0.046
organic substance catabolic process GO:1901575 316 0.046
aging GO:0007568 241 0.046
behavior GO:0007610 205 0.045
cellular divalent inorganic cation homeostasis GO:0072503 162 0.045
chemical homeostasis GO:0048878 292 0.044
response to bacterium GO:0009617 200 0.044
g protein coupled receptor signaling pathway GO:0007186 242 0.044
ribonucleotide metabolic process GO:0009259 231 0.044
neurological system process GO:0050877 219 0.043
regulation of molecular function GO:0065009 398 0.041
response to alkaloid GO:0043279 132 0.041
regulation of programmed cell death GO:0043067 341 0.041
single organism biosynthetic process GO:0044711 342 0.041
positive regulation of signaling GO:0023056 270 0.041
carbohydrate derivative metabolic process GO:1901135 346 0.040
negative regulation of metabolic process GO:0009892 331 0.040
organelle organization GO:0006996 266 0.040
response to lipopolysaccharide GO:0032496 191 0.039
cellular response to endogenous stimulus GO:0071495 377 0.039
cellular catabolic process GO:0044248 295 0.039
organic acid metabolic process GO:0006082 292 0.039
response to decreased oxygen levels GO:0036293 237 0.038
organophosphate metabolic process GO:0019637 370 0.038
purine nucleotide metabolic process GO:0006163 229 0.038
calcium ion transport GO:0006816 131 0.038
transmembrane transport GO:0055085 412 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
cellular response to growth factor stimulus GO:0071363 162 0.037
response to estrogen GO:0043627 232 0.037
cellular component biogenesis GO:0044085 368 0.036
cellular calcium ion homeostasis GO:0006874 160 0.036
positive regulation of cell proliferation GO:0008284 249 0.036
secretion GO:0046903 307 0.035
organic acid transport GO:0015849 116 0.035
single organism catabolic process GO:0044712 283 0.035
nucleotide metabolic process GO:0009117 279 0.034
single organism organelle organization GO:1902589 180 0.034
regulation of apoptotic process GO:0042981 335 0.034
regulation of phosphate metabolic process GO:0019220 349 0.034
carboxylic acid transport GO:0046942 115 0.034
cellular response to stress GO:0033554 269 0.034
catabolic process GO:0009056 351 0.034
regulation of response to external stimulus GO:0032101 106 0.034
rna biosynthetic process GO:0032774 380 0.033
macromolecular complex subunit organization GO:0043933 339 0.033
cation homeostasis GO:0055080 195 0.033
neuron differentiation GO:0030182 368 0.033
transcription dna templated GO:0006351 377 0.032
cyclic purine nucleotide metabolic process GO:0052652 62 0.032
regulation of catalytic activity GO:0050790 304 0.032
response to biotic stimulus GO:0009607 226 0.032
regulation of rna biosynthetic process GO:2001141 381 0.032
response to extracellular stimulus GO:0009991 380 0.032
cellular homeostasis GO:0019725 252 0.031
gliogenesis GO:0042063 93 0.031
purine containing compound metabolic process GO:0072521 253 0.031
single organism behavior GO:0044708 130 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
metal ion homeostasis GO:0055065 186 0.030
ribose phosphate metabolic process GO:0019693 235 0.030
positive regulation of cellular component organization GO:0051130 200 0.030
response to growth factor GO:0070848 189 0.030
rna metabolic process GO:0016070 406 0.030
cytosolic calcium ion homeostasis GO:0051480 140 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
regulation of protein metabolic process GO:0051246 289 0.030
carboxylic acid metabolic process GO:0019752 289 0.030
regulation of secretion by cell GO:1903530 208 0.030
regulation of cellular localization GO:0060341 263 0.029
negative regulation of cellular metabolic process GO:0031324 281 0.029
inflammatory response GO:0006954 150 0.029
positive regulation of ion transport GO:0043270 94 0.029
positive regulation of secretion by cell GO:1903532 128 0.029
regulation of metal ion transport GO:0010959 118 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.029
macromolecular complex assembly GO:0065003 273 0.029
cellular response to nitrogen compound GO:1901699 210 0.029
cell cell signaling GO:0007267 335 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.028
cyclic nucleotide metabolic process GO:0009187 80 0.028
organophosphate biosynthetic process GO:0090407 143 0.027
response to toxic substance GO:0009636 133 0.027
calcium ion homeostasis GO:0055074 162 0.027
glial cell differentiation GO:0010001 65 0.027
divalent inorganic cation transport GO:0072511 134 0.027
response to other organism GO:0051707 220 0.027
single organism reproductive process GO:0044702 297 0.027
response to cytokine GO:0034097 215 0.027
purine ribonucleotide metabolic process GO:0009150 227 0.027
protein phosphorylation GO:0006468 345 0.027
cellular component assembly GO:0022607 360 0.027
ribonucleotide biosynthetic process GO:0009260 85 0.027
cellular response to organic cyclic compound GO:0071407 202 0.026
cellular metal ion homeostasis GO:0006875 172 0.026
single organism carbohydrate metabolic process GO:0044723 118 0.026
regulation of synaptic transmission GO:0050804 141 0.026
intracellular signal transduction GO:0035556 314 0.026
negative regulation of multicellular organismal process GO:0051241 203 0.025
negative regulation of gene expression GO:0010629 199 0.025
fatty acid metabolic process GO:0006631 99 0.025
astrocyte development GO:0014002 4 0.025
divalent inorganic cation homeostasis GO:0072507 165 0.025
protein complex biogenesis GO:0070271 263 0.025
inorganic cation transmembrane transport GO:0098662 202 0.024
oxoacid metabolic process GO:0043436 290 0.024
response to nutrient levels GO:0031667 370 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
response to ethanol GO:0045471 162 0.024
nucleic acid templated transcription GO:0097659 379 0.024
response to estradiol GO:0032355 164 0.024
cognition GO:0050890 92 0.024
organonitrogen compound biosynthetic process GO:1901566 167 0.023
negative regulation of phosphate metabolic process GO:0045936 80 0.023
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.023
positive regulation of synaptic transmission GO:0050806 62 0.023
regulation of purine nucleotide metabolic process GO:1900542 115 0.023
nucleoside phosphate biosynthetic process GO:1901293 102 0.023
regulation of neuron projection development GO:0010975 161 0.023
negative regulation of programmed cell death GO:0043069 183 0.023
response to mechanical stimulus GO:0009612 134 0.023
regulation of cell differentiation GO:0045595 320 0.023
secretion by cell GO:0032940 248 0.023
cyclic nucleotide biosynthetic process GO:0009190 63 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
transcription from rna polymerase ii promoter GO:0006366 252 0.022
nucleotide biosynthetic process GO:0009165 98 0.022
response to ketone GO:1901654 182 0.022
reproductive process GO:0022414 372 0.022
negative regulation of developmental process GO:0051093 125 0.022
ribose phosphate biosynthetic process GO:0046390 87 0.022
response to peptide GO:1901652 292 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
wound healing GO:0042060 122 0.022
cellular component movement GO:0006928 248 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.022
regulation of hormone secretion GO:0046883 106 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
cellular response to hormone stimulus GO:0032870 247 0.021
macromolecule localization GO:0033036 252 0.021
protein oligomerization GO:0051259 191 0.021
cell projection organization GO:0030030 302 0.021
protein complex subunit organization GO:0071822 302 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
positive regulation of cell death GO:0010942 184 0.021
female pregnancy GO:0007565 122 0.021
response to oxidative stress GO:0006979 186 0.021
positive regulation of cell development GO:0010720 176 0.021
regulation of locomotion GO:0040012 148 0.021
multi organism reproductive process GO:0044703 262 0.021
response to acid chemical GO:0001101 222 0.021
neuron projection development GO:0031175 273 0.020
positive regulation of gene expression GO:0010628 244 0.020
camp metabolic process GO:0046058 63 0.020
cell type specific apoptotic process GO:0097285 134 0.020
acute inflammatory response GO:0002526 58 0.020
purine nucleotide biosynthetic process GO:0006164 83 0.019
ras protein signal transduction GO:0007265 29 0.019
regulation of multicellular organismal development GO:2000026 376 0.019
regulation of cell development GO:0060284 263 0.019
growth GO:0040007 165 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.019
anatomical structure morphogenesis GO:0009653 298 0.019
nitrogen compound transport GO:0071705 229 0.019
regulation of membrane potential GO:0042391 110 0.019
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.018
protein complex assembly GO:0006461 263 0.018
response to ammonium ion GO:0060359 71 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
regeneration GO:0031099 163 0.018
regulation of signal transduction GO:0009966 318 0.018
eye morphogenesis GO:0048592 4 0.018
potassium ion transport GO:0006813 97 0.018
regulation of phosphorylation GO:0042325 248 0.018
response to carbohydrate GO:0009743 183 0.018
positive regulation of response to external stimulus GO:0032103 51 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
response to temperature stimulus GO:0009266 94 0.018
cellular amide metabolic process GO:0043603 44 0.018
regulation of camp metabolic process GO:0030814 43 0.018
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
regulation of cell motility GO:2000145 131 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
response to radiation GO:0009314 137 0.018
positive regulation of nervous system development GO:0051962 178 0.018
negative regulation of apoptotic process GO:0043066 181 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
regulation of neurogenesis GO:0050767 247 0.017
mapk cascade GO:0000165 140 0.017
regulation of neuron differentiation GO:0045664 208 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.017
hormone transport GO:0009914 121 0.017
circulatory system process GO:0003013 183 0.017
regulation of rna metabolic process GO:0051252 391 0.017
long term synaptic potentiation GO:0060291 21 0.017
positive regulation of immune system process GO:0002684 90 0.017
response to vitamin GO:0033273 131 0.017
regulation of calcium ion transport GO:0051924 77 0.017
positive regulation of secretion GO:0051047 140 0.016
positive regulation of molecular function GO:0044093 230 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
regulation of transcription dna templated GO:0006355 374 0.016
response to monosaccharide GO:0034284 159 0.016
reproductive structure development GO:0048608 128 0.016
regulation of nervous system development GO:0051960 264 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
schwann cell migration GO:0036135 2 0.016
purine containing compound biosynthetic process GO:0072522 85 0.016
positive regulation of developmental process GO:0051094 283 0.016
cellular response to peptide GO:1901653 133 0.016
cell activation GO:0001775 97 0.016
locomotion GO:0040011 237 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
response to amino acid GO:0043200 75 0.016
cell motility GO:0048870 202 0.016
positive regulation of hormone secretion GO:0046887 65 0.016
regulation of nucleotide biosynthetic process GO:0030808 47 0.016
multicellular organism reproduction GO:0032504 233 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
muscle system process GO:0003012 115 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
regulation of protein modification process GO:0031399 194 0.015
response to axon injury GO:0048678 59 0.015
developmental process involved in reproduction GO:0003006 159 0.015
signal release GO:0023061 145 0.015
response to zinc ion GO:0010043 39 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
regulation of cell migration GO:0030334 128 0.015
multicellular organismal reproductive process GO:0048609 233 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.014
proteolysis GO:0006508 175 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
reproduction GO:0000003 245 0.014
regulation of mapk cascade GO:0043408 116 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
regulation of hormone levels GO:0010817 187 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
cellular amine metabolic process GO:0044106 38 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
regulation of homeostatic process GO:0032844 101 0.014
cytoskeleton organization GO:0007010 111 0.014
cation transmembrane transport GO:0098655 263 0.014
blood circulation GO:0008015 183 0.014
intracellular transport GO:0046907 185 0.014
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.014
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
developmental growth GO:0048589 100 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
regulation of anatomical structure size GO:0090066 135 0.013
regulation of transferase activity GO:0051338 123 0.013
muscle contraction GO:0006936 88 0.013
cellular lipid metabolic process GO:0044255 208 0.013
regulation of camp biosynthetic process GO:0030817 38 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
regulation of secretion GO:0051046 224 0.013
negative regulation of skeletal muscle tissue development GO:0048642 3 0.013
single organism intracellular transport GO:1902582 166 0.013
sensory perception GO:0007600 101 0.013
protein heterooligomerization GO:0051291 89 0.013
regulation of immune system process GO:0002682 123 0.013
organic hydroxy compound transport GO:0015850 77 0.013
regulation of transmembrane transport GO:0034762 122 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
positive regulation of blood circulation GO:1903524 65 0.012
negative regulation of cell death GO:0060548 229 0.012
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
respiratory system process GO:0003016 3 0.012
regulation of inflammatory response GO:0050727 48 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
nucleoside metabolic process GO:0009116 179 0.012
positive regulation of peptide secretion GO:0002793 52 0.012
cell cycle GO:0007049 101 0.012
oxidation reduction process GO:0055114 304 0.012
positive regulation of protein modification process GO:0031401 142 0.012
cellular ketone metabolic process GO:0042180 51 0.012
regulation of transmembrane transporter activity GO:0022898 49 0.012
retina morphogenesis in camera type eye GO:0060042 1 0.012
anion transport GO:0006820 178 0.012
amine metabolic process GO:0009308 38 0.012
diaphragm contraction GO:0002086 2 0.012
response to antibiotic GO:0046677 39 0.012
positive regulation of calcium ion transport GO:0051928 36 0.012
actin filament based process GO:0030029 86 0.012
learning or memory GO:0007611 90 0.012
response to insulin GO:0032868 133 0.012
regulation of cellular component movement GO:0051270 150 0.012
lipid transport GO:0006869 61 0.012
response to purine containing compound GO:0014074 126 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
multicellular organism growth GO:0035264 1 0.012
peptide secretion GO:0002790 86 0.012
negative regulation of molecular function GO:0044092 133 0.012
response to organophosphorus GO:0046683 102 0.012
camp biosynthetic process GO:0006171 47 0.012
salivary gland development GO:0007431 3 0.012
cellular response to lipopolysaccharide GO:0071222 55 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
sodium ion transmembrane transport GO:0035725 67 0.012
peptide transport GO:0015833 97 0.012
chromosome segregation GO:0007059 2 0.011
regulation of cell projection organization GO:0031344 175 0.011
cellular response to oxygen levels GO:0071453 60 0.011
response to reactive oxygen species GO:0000302 120 0.011
regulation of blood circulation GO:1903522 110 0.011
forebrain development GO:0030900 98 0.011
immune system process GO:0002376 204 0.011
lipid metabolic process GO:0006629 283 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
carbohydrate metabolic process GO:0005975 130 0.011
response to nutrient GO:0007584 248 0.011
regulation of hydrolase activity GO:0051336 143 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
epithelium development GO:0060429 96 0.011
hormone secretion GO:0046879 115 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
sequestering of metal ion GO:0051238 9 0.011
atp catabolic process GO:0006200 54 0.011
response to fatty acid GO:0070542 65 0.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.011
acid secretion GO:0046717 48 0.011
response to hyperoxia GO:0055093 45 0.011
localization of cell GO:0051674 202 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
cytoplasmic transport GO:0016482 115 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
actin cytoskeleton organization GO:0030036 73 0.011
regulation of schwann cell migration GO:1900147 2 0.010
organophosphate catabolic process GO:0046434 148 0.010
response to hexose GO:0009746 144 0.010
sequestering of calcium ion GO:0051208 8 0.010
cellular component morphogenesis GO:0032989 155 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
response to heat GO:0009408 60 0.010
purine nucleotide catabolic process GO:0006195 136 0.010
response to glucose GO:0009749 136 0.010
positive regulation of transcription dna templated GO:0045893 197 0.010
regulation of neuron apoptotic process GO:0043523 83 0.010
reproductive system development GO:0061458 128 0.010
regulation of body fluid levels GO:0050878 90 0.010
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.010
response to hydrogen peroxide GO:0042542 89 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
negative regulation of cell communication GO:0010648 158 0.010
positive regulation of transport GO:0051050 245 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
neuronal action potential GO:0019228 35 0.010
heart contraction GO:0060047 57 0.010
cellular response to hypoxia GO:0071456 51 0.010
sensory perception of pain GO:0019233 73 0.010

Mt3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
eye disease DOID:5614 0 0.017
disease of metabolism DOID:0014667 0 0.011