Rattus norvegicus

27 known processes

Macf1

microtubule-actin crosslinking factor 1

Macf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.171
regulation of phosphate metabolic process GO:0019220 349 0.152
positive regulation of multicellular organismal process GO:0051240 387 0.151
regulation of signal transduction GO:0009966 318 0.134
cellular component movement GO:0006928 248 0.121
single organism catabolic process GO:0044712 283 0.119
neuron projection development GO:0031175 273 0.116
regulation of intracellular signal transduction GO:1902531 218 0.113
positive regulation of cellular biosynthetic process GO:0031328 295 0.111
positive regulation of phosphate metabolic process GO:0045937 262 0.109
nucleobase containing small molecule metabolic process GO:0055086 316 0.108
regulation of cellular ketone metabolic process GO:0010565 27 0.107
regulation of phosphorus metabolic process GO:0051174 349 0.102
oxoacid metabolic process GO:0043436 290 0.101
cellular amino acid metabolic process GO:0006520 107 0.093
cellular component assembly GO:0022607 360 0.091
cellular catabolic process GO:0044248 295 0.090
carboxylic acid metabolic process GO:0019752 289 0.089
cell projection organization GO:0030030 302 0.088
intracellular signal transduction GO:0035556 314 0.088
neuron death GO:0070997 127 0.087
locomotion GO:0040011 237 0.084
positive regulation of developmental process GO:0051094 283 0.084
head development GO:0060322 247 0.083
catabolic process GO:0009056 351 0.082
positive regulation of cell projection organization GO:0031346 111 0.082
positive regulation of neurogenesis GO:0050769 165 0.082
programmed cell death GO:0012501 392 0.081
regulation of protein phosphorylation GO:0001932 183 0.076
regulation of molecular function GO:0065009 398 0.073
regulation of phosphorylation GO:0042325 248 0.073
anatomical structure morphogenesis GO:0009653 298 0.072
regulation of nervous system development GO:0051960 264 0.071
cellular component biogenesis GO:0044085 368 0.068
g protein coupled receptor signaling pathway GO:0007186 242 0.068
protein localization GO:0008104 191 0.067
regulation of cellular component organization GO:0051128 368 0.067
regulation of apoptotic process GO:0042981 335 0.067
neuron differentiation GO:0030182 368 0.062
regulation of protein modification process GO:0031399 194 0.062
macromolecule localization GO:0033036 252 0.061
cellular response to growth factor stimulus GO:0071363 162 0.061
protein complex subunit organization GO:0071822 302 0.059
cellular response to endogenous stimulus GO:0071495 377 0.059
regulation of cellular protein metabolic process GO:0032268 267 0.058
protein heterooligomerization GO:0051291 89 0.058
regulation of locomotion GO:0040012 148 0.058
regulation of transferase activity GO:0051338 123 0.057
cellular response to stress GO:0033554 269 0.057
protein complex assembly GO:0006461 263 0.057
regulation of multicellular organismal development GO:2000026 376 0.057
negative regulation of developmental process GO:0051093 125 0.055
protein phosphorylation GO:0006468 345 0.055
gap junction assembly GO:0016264 2 0.054
protein complex biogenesis GO:0070271 263 0.054
regulation of mapk cascade GO:0043408 116 0.053
regulation of neurogenesis GO:0050767 247 0.053
macromolecular complex assembly GO:0065003 273 0.052
response to growth factor GO:0070848 189 0.051
negative regulation of cell differentiation GO:0045596 99 0.051
positive regulation of phosphorus metabolic process GO:0010562 262 0.050
ras protein signal transduction GO:0007265 29 0.050
regulation of cellular amino acid metabolic process GO:0006521 2 0.050
positive regulation of cell death GO:0010942 184 0.049
positive regulation of biosynthetic process GO:0009891 319 0.049
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.049
cation homeostasis GO:0055080 195 0.048
cell cell signaling GO:0007267 335 0.048
positive regulation of amine transport GO:0051954 26 0.047
positive regulation of nervous system development GO:0051962 178 0.047
regulation of cell projection organization GO:0031344 175 0.046
regulation of cell differentiation GO:0045595 320 0.046
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.046
macromolecular complex subunit organization GO:0043933 339 0.045
neuron development GO:0048666 286 0.045
mapk cascade GO:0000165 140 0.044
cellular response to nitrogen compound GO:1901699 210 0.044
inorganic ion transmembrane transport GO:0098660 229 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
regulation of cellular amine metabolic process GO:0033238 8 0.043
positive regulation of cell differentiation GO:0045597 217 0.043
regulation of cellular localization GO:0060341 263 0.042
response to purine containing compound GO:0014074 126 0.042
cell morphogenesis involved in differentiation GO:0000904 119 0.041
cellular response to oxygen containing compound GO:1901701 386 0.040
organophosphate catabolic process GO:0046434 148 0.040
positive regulation of cell migration GO:0030335 96 0.040
organelle organization GO:0006996 266 0.040
signal transduction by phosphorylation GO:0023014 144 0.039
amine metabolic process GO:0009308 38 0.039
small gtpase mediated signal transduction GO:0007264 36 0.039
carbohydrate metabolic process GO:0005975 130 0.039
regulation of neuron differentiation GO:0045664 208 0.038
positive regulation of cellular component organization GO:0051130 200 0.038
cellular ketone metabolic process GO:0042180 51 0.038
apoptotic process GO:0006915 381 0.038
regulation of programmed cell death GO:0043067 341 0.038
response to oxygen levels GO:0070482 265 0.037
tissue development GO:0009888 252 0.037
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.036
regulation of neuron projection development GO:0010975 161 0.036
intracellular transport GO:0046907 185 0.036
negative regulation of cell communication GO:0010648 158 0.036
cellular response to organonitrogen compound GO:0071417 197 0.036
regulation of cellular component movement GO:0051270 150 0.036
cellular amine metabolic process GO:0044106 38 0.035
protein oligomerization GO:0051259 191 0.035
positive regulation of response to stimulus GO:0048584 285 0.035
positive regulation of cell development GO:0010720 176 0.035
positive regulation of ras gtpase activity GO:0032320 28 0.034
synaptic transmission GO:0007268 235 0.033
positive regulation of programmed cell death GO:0043068 157 0.033
cell migration GO:0016477 197 0.033
regulation of catalytic activity GO:0050790 304 0.033
positive regulation of gtpase activity GO:0043547 47 0.033
purine ribonucleotide metabolic process GO:0009150 227 0.033
neurological system process GO:0050877 219 0.033
positive regulation of protein metabolic process GO:0051247 178 0.032
cellular ion homeostasis GO:0006873 184 0.032
chemical homeostasis GO:0048878 292 0.032
inorganic cation transmembrane transport GO:0098662 202 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.032
purine containing compound catabolic process GO:0072523 138 0.031
regulation of cell morphogenesis GO:0022604 77 0.031
response to organophosphorus GO:0046683 102 0.030
positive regulation of neuron projection development GO:0010976 99 0.030
positive regulation of phosphorylation GO:0042327 177 0.030
cell cycle GO:0007049 101 0.030
regulation of cell development GO:0060284 263 0.029
localization of cell GO:0051674 202 0.029
regulation of neuron death GO:1901214 115 0.029
cell projection morphogenesis GO:0048858 123 0.029
regulation of cell proliferation GO:0042127 359 0.028
regulation of cell motility GO:2000145 131 0.028
organic substance catabolic process GO:1901575 316 0.028
multicellular organism growth GO:0035264 1 0.027
negative regulation of signaling GO:0023057 157 0.027
cell morphogenesis GO:0000902 142 0.027
negative regulation of cellular component organization GO:0051129 83 0.027
regulation of anatomical structure morphogenesis GO:0022603 141 0.027
cellular protein localization GO:0034613 122 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.027
cellular divalent inorganic cation homeostasis GO:0072503 162 0.027
positive regulation of locomotion GO:0040017 102 0.026
reproductive process GO:0022414 372 0.026
Rat
cytosolic calcium ion homeostasis GO:0051480 140 0.026
regulation of synaptic transmission GO:0050804 141 0.026
enzyme linked receptor protein signaling pathway GO:0007167 116 0.026
brain development GO:0007420 247 0.026
heterocycle catabolic process GO:0046700 167 0.025
negative regulation of signal transduction GO:0009968 83 0.025
regulation of protein metabolic process GO:0051246 289 0.025
nitrogen compound transport GO:0071705 229 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.025
axonogenesis GO:0007409 71 0.025
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.025
cation transport GO:0006812 382 0.025
regulation of hydrolase activity GO:0051336 143 0.025
carbohydrate derivative catabolic process GO:1901136 147 0.025
lipid metabolic process GO:0006629 283 0.025
single organism intracellular transport GO:1902582 166 0.025
cardiovascular system development GO:0072358 134 0.025
positive regulation of molecular function GO:0044093 230 0.025
central nervous system development GO:0007417 311 0.025
regulation of cell migration GO:0030334 128 0.024
action potential GO:0001508 54 0.024
positive regulation of intracellular signal transduction GO:1902533 138 0.024
ion transmembrane transport GO:0034220 365 0.024
negative regulation of response to stimulus GO:0048585 155 0.024
calcium ion homeostasis GO:0055074 162 0.024
homeostatic process GO:0042592 331 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.024
circulatory system development GO:0072359 134 0.024
positive regulation of transport GO:0051050 245 0.024
metal ion homeostasis GO:0055065 186 0.024
positive regulation of cellular component movement GO:0051272 102 0.023
organonitrogen compound catabolic process GO:1901565 179 0.023
developmental growth GO:0048589 100 0.023
positive regulation of neuron differentiation GO:0045666 126 0.023
cellular homeostasis GO:0019725 252 0.023
positive regulation of nucleotide metabolic process GO:0045981 91 0.023
response to extracellular stimulus GO:0009991 380 0.023
Rat
cell part morphogenesis GO:0032990 123 0.022
cytoskeleton organization GO:0007010 111 0.022
positive regulation of cell motility GO:2000147 97 0.022
secretion by cell GO:0032940 248 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
response to metal ion GO:0010038 253 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
purine ribonucleoside catabolic process GO:0046130 124 0.022
regulation of kinase activity GO:0043549 117 0.022
transmembrane transport GO:0055085 412 0.022
cell type specific apoptotic process GO:0097285 134 0.022
alcohol metabolic process GO:0006066 77 0.021
cellular metal ion homeostasis GO:0006875 172 0.021
reproduction GO:0000003 245 0.021
ion homeostasis GO:0050801 212 0.021
regulation of canonical wnt signaling pathway GO:0060828 4 0.021
rna biosynthetic process GO:0032774 380 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.021
regulation of ras gtpase activity GO:0032318 32 0.021
positive regulation of cell communication GO:0010647 271 0.021
single organism organelle organization GO:1902589 180 0.021
response to acid chemical GO:0001101 222 0.021
cellular component morphogenesis GO:0032989 155 0.021
regulation of ion transport GO:0043269 245 0.021
cellular macromolecule localization GO:0070727 122 0.020
positive regulation of protein modification process GO:0031401 142 0.020
response to carbohydrate GO:0009743 183 0.020
cell cycle process GO:0022402 57 0.020
response to increased oxygen levels GO:0036296 45 0.020
ribonucleoside catabolic process GO:0042454 126 0.020
calcium ion transport GO:0006816 131 0.020
regulation of anatomical structure size GO:0090066 135 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
response to decreased oxygen levels GO:0036293 237 0.019
motor neuron axon guidance GO:0008045 1 0.019
positive regulation of mapk cascade GO:0043410 92 0.019
protein targeting GO:0006605 61 0.019
cellular lipid metabolic process GO:0044255 208 0.019
glycosyl compound catabolic process GO:1901658 126 0.019
metal ion transport GO:0030001 289 0.019
cellular chemical homeostasis GO:0055082 247 0.018
response to hypoxia GO:0001666 231 0.018
regulation of protein kinase activity GO:0045859 105 0.018
regulation of cellular component biogenesis GO:0044087 86 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
regulation of small gtpase mediated signal transduction GO:0051056 48 0.018
response to alkaloid GO:0043279 132 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
positive regulation of norepinephrine secretion GO:0010701 4 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
eye morphogenesis GO:0048592 4 0.018
regulation of gtpase activity GO:0043087 57 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
carboxylic acid transport GO:0046942 115 0.018
positive regulation of secretion by cell GO:1903532 128 0.018
cation transmembrane transport GO:0098655 263 0.018
protein tetramerization GO:0051262 38 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.017
protein modification by small protein conjugation GO:0032446 31 0.017
stress activated protein kinase signaling cascade GO:0031098 37 0.017
metanephric comma shaped body morphogenesis GO:0072278 2 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.017
growth GO:0040007 165 0.017
multi organism reproductive process GO:0044703 262 0.017
Rat
single organism carbohydrate metabolic process GO:0044723 118 0.017
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.017
cytoskeleton dependent cytokinesis GO:0061640 2 0.017
sequestering of calcium ion GO:0051208 8 0.017
regulation of neuron apoptotic process GO:0043523 83 0.017
cell motility GO:0048870 202 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
neuron projection morphogenesis GO:0048812 122 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
amine transport GO:0015837 57 0.016
cellular cation homeostasis GO:0030003 180 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
transcription from rna polymerase ii promoter GO:0006366 252 0.016
purine nucleoside catabolic process GO:0006152 124 0.016
vesicle mediated transport GO:0016192 181 0.016
aromatic compound catabolic process GO:0019439 168 0.016
regulation of secretion GO:0051046 224 0.016
protein transport GO:0015031 132 0.016
nucleoside metabolic process GO:0009116 179 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
secretion GO:0046903 307 0.016
positive regulation of gene expression GO:0010628 244 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
regulation of rna biosynthetic process GO:2001141 381 0.016
taxis GO:0042330 67 0.016
regulation of transcription dna templated GO:0006355 374 0.015
rna metabolic process GO:0016070 406 0.015
positive regulation of signaling GO:0023056 270 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
regulation of cell cycle GO:0051726 73 0.015
axis specification GO:0009798 4 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
divalent inorganic cation transport GO:0072511 134 0.015
anatomical structure formation involved in morphogenesis GO:0048646 83 0.015
regulation of response to stress GO:0080134 126 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
calcium ion transmembrane transport GO:0070588 70 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
purine nucleoside triphosphate catabolic process GO:0009146 122 0.015
regulation of purine nucleotide catabolic process GO:0033121 65 0.015
nucleoside triphosphate catabolic process GO:0009143 123 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
gastrulation GO:0007369 2 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
stress activated mapk cascade GO:0051403 35 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
gtp catabolic process GO:0006184 71 0.014
organelle localization GO:0051640 55 0.014
actin filament based process GO:0030029 86 0.014
regulation of metal ion transport GO:0010959 118 0.014
multicellular organism reproduction GO:0032504 233 0.014
regulation of calcium ion transport GO:0051924 77 0.014
response to inorganic substance GO:0010035 377 0.014
rho protein signal transduction GO:0007266 11 0.014
response to peptide GO:1901652 292 0.014
anion transport GO:0006820 178 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
regeneration GO:0031099 163 0.014
cellular response to lipid GO:0071396 201 0.014
establishment of protein localization GO:0045184 141 0.014
cytoplasmic transport GO:0016482 115 0.014
organic hydroxy compound transport GO:0015850 77 0.014
positive regulation of ion transport GO:0043270 94 0.013
heart development GO:0007507 72 0.013
actin cytoskeleton organization GO:0030036 73 0.013
organic anion transport GO:0015711 132 0.013
neuron projection guidance GO:0097485 24 0.013
maintenance of location GO:0051235 17 0.013
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.013
positive regulation of secretion GO:0051047 140 0.013
potassium ion transport GO:0006813 97 0.013
organophosphate metabolic process GO:0019637 370 0.013
regulation of secretion by cell GO:1903530 208 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
axon development GO:0061564 96 0.013
regulation of rna metabolic process GO:0051252 391 0.013
regulation of response to external stimulus GO:0032101 106 0.013
retinal ganglion cell axon guidance GO:0031290 1 0.013
chemotaxis GO:0006935 66 0.013
regulation of system process GO:0044057 208 0.013
dicarboxylic acid transport GO:0006835 34 0.013
chromosome segregation GO:0007059 2 0.013
positive regulation of signal transduction GO:0009967 175 0.013
anterior posterior pattern specification GO:0009952 1 0.013
amino acid transport GO:0006865 70 0.013
negative regulation of neuron differentiation GO:0045665 62 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
positive regulation of rna metabolic process GO:0051254 203 0.012
negative regulation of cell projection organization GO:0031345 50 0.012
positive regulation of cellular component biogenesis GO:0044089 55 0.012
behavior GO:0007610 205 0.012
sequestering of metal ion GO:0051238 9 0.012
regulation of ras protein signal transduction GO:0046578 45 0.012
sexual reproduction GO:0019953 148 0.012
muscle system process GO:0003012 115 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
muscle cell differentiation GO:0042692 52 0.012
divalent metal ion transport GO:0070838 132 0.012
phospholipid metabolic process GO:0006644 61 0.012
forebrain development GO:0030900 98 0.012
response to monosaccharide GO:0034284 159 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
response to wounding GO:0009611 254 0.012
regulation of growth GO:0040008 105 0.012
transmission of nerve impulse GO:0019226 42 0.012
negative regulation of cell death GO:0060548 229 0.012
negative regulation of gene expression GO:0010629 199 0.012
regulation of jnk cascade GO:0046328 19 0.012
response to peptide hormone GO:0043434 278 0.012
response to hyperoxia GO:0055093 45 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
dna metabolic process GO:0006259 96 0.011
regulation of gtp catabolic process GO:0033124 58 0.011
learning or memory GO:0007611 90 0.011
positive regulation of nucleoside metabolic process GO:0045979 55 0.011
nucleic acid templated transcription GO:0097659 379 0.011
response to estrogen GO:0043627 232 0.011
intracellular protein transport GO:0006886 79 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
response to external biotic stimulus GO:0043207 221 0.011
pyrimidine nucleobase catabolic process GO:0006208 3 0.011
jnk cascade GO:0007254 28 0.011
immune response GO:0006955 104 0.011
sympathetic nervous system development GO:0048485 1 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
single organism cellular localization GO:1902580 102 0.011
response to oxidative stress GO:0006979 186 0.011
neuron apoptotic process GO:0051402 88 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
response to insulin GO:0032868 133 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
multicellular organismal signaling GO:0035637 44 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.011
cytosolic calcium ion transport GO:0060401 39 0.011
single organism biosynthetic process GO:0044711 342 0.011
blood vessel development GO:0001568 69 0.011
response to magnesium ion GO:0032026 20 0.011
response to fatty acid GO:0070542 65 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
axon guidance GO:0007411 24 0.011
purine containing compound metabolic process GO:0072521 253 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
regulation of dendrite development GO:0050773 59 0.010
positive regulation of catabolic process GO:0009896 78 0.010
catecholamine secretion GO:0050432 33 0.010
defense response GO:0006952 194 0.010
striated muscle tissue development GO:0014706 58 0.010
response to ammonium ion GO:0060359 71 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
nucleotide catabolic process GO:0009166 139 0.010
rhythmic process GO:0048511 156 0.010
regulation of protein localization GO:0032880 81 0.010
peptidyl amino acid modification GO:0018193 126 0.010
sensory perception of bitter taste GO:0050913 4 0.010
regulation of cellular response to stress GO:0080135 49 0.010
negative regulation of cell development GO:0010721 82 0.010
regulation of synaptic plasticity GO:0048167 70 0.010
negative regulation of neuron projection development GO:0010977 46 0.010
negative regulation of multicellular organismal process GO:0051241 203 0.010
regulation of hormone levels GO:0010817 187 0.010
cellular carbohydrate metabolic process GO:0044262 72 0.010
positive regulation of gtp catabolic process GO:0033126 48 0.010
response to calcium ion GO:0051592 59 0.010

Macf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
urinary system disease DOID:18 0 0.016
central nervous system disease DOID:331 0 0.013
kidney disease DOID:557 0 0.011