Rattus norvegicus

0 known processes

Ell

elongation factor RNA polymerase II

Ell biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.107
Human
regulation of molecular function GO:0065009 398 0.093
Human
programmed cell death GO:0012501 392 0.082
regulation of transcription dna templated GO:0006355 374 0.077
Human
regulation of protein modification process GO:0031399 194 0.069
regulation of phosphate metabolic process GO:0019220 349 0.069
Human
intracellular signal transduction GO:0035556 314 0.068
regulation of rna biosynthetic process GO:2001141 381 0.068
Human
positive regulation of multicellular organismal process GO:0051240 387 0.066
cellular response to oxygen containing compound GO:1901701 386 0.062
regulation of signal transduction GO:0009966 318 0.059
regulation of protein metabolic process GO:0051246 289 0.057
rna biosynthetic process GO:0032774 380 0.055
Human
regulation of cellular ketone metabolic process GO:0010565 27 0.055
protein phosphorylation GO:0006468 345 0.055
cellular ketone metabolic process GO:0042180 51 0.054
transmembrane transport GO:0055085 412 0.054
regulation of cell differentiation GO:0045595 320 0.051
regulation of multicellular organismal development GO:2000026 376 0.049
regulation of protein phosphorylation GO:0001932 183 0.049
regulation of apoptotic process GO:0042981 335 0.047
regulation of rna metabolic process GO:0051252 391 0.046
Human
regulation of programmed cell death GO:0043067 341 0.046
tissue development GO:0009888 252 0.046
regulation of phosphorus metabolic process GO:0051174 349 0.045
Human
reproductive process GO:0022414 372 0.044
organic substance catabolic process GO:1901575 316 0.044
regulation of cellular protein metabolic process GO:0032268 267 0.043
cellular amino acid metabolic process GO:0006520 107 0.043
Rat
positive regulation of cell communication GO:0010647 271 0.042
positive regulation of rna biosynthetic process GO:1902680 197 0.042
Human
neuron differentiation GO:0030182 368 0.041
apoptotic process GO:0006915 381 0.041
positive regulation of molecular function GO:0044093 230 0.040
regulation of intracellular signal transduction GO:1902531 218 0.040
cellular amine metabolic process GO:0044106 38 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
Human
regulation of phosphorylation GO:0042325 248 0.039
oxoacid metabolic process GO:0043436 290 0.039
Rat
positive regulation of transcription dna templated GO:0045893 197 0.039
Human
nucleic acid templated transcription GO:0097659 379 0.038
Human
cellular response to hormone stimulus GO:0032870 247 0.037
single organism reproductive process GO:0044702 297 0.036
regulation of nervous system development GO:0051960 264 0.036
regulation of transferase activity GO:0051338 123 0.034
positive regulation of protein metabolic process GO:0051247 178 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.033
negative regulation of metabolic process GO:0009892 331 0.033
Human
negative regulation of apoptotic process GO:0043066 181 0.033
positive regulation of response to stimulus GO:0048584 285 0.032
amine metabolic process GO:0009308 38 0.032
cellular response to biotic stimulus GO:0071216 59 0.032
positive regulation of developmental process GO:0051094 283 0.032
secretion GO:0046903 307 0.032
regulation of secretion GO:0051046 224 0.031
positive regulation of rna metabolic process GO:0051254 203 0.031
Human
multicellular organism reproduction GO:0032504 233 0.031
regulation of kinase activity GO:0043549 117 0.031
catabolic process GO:0009056 351 0.031
transcription from rna polymerase ii promoter GO:0006366 252 0.030
Human
positive regulation of phosphate metabolic process GO:0045937 262 0.030
anion transport GO:0006820 178 0.030
negative regulation of molecular function GO:0044092 133 0.030
Human
cellular response to lipid GO:0071396 201 0.030
cytokine biosynthetic process GO:0042089 3 0.029
cellular response to endogenous stimulus GO:0071495 377 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
response to other organism GO:0051707 220 0.027
reproduction GO:0000003 245 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
organophosphate metabolic process GO:0019637 370 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
Human
regulation of cell proliferation GO:0042127 359 0.027
positive regulation of catalytic activity GO:0043085 184 0.027
multi organism reproductive process GO:0044703 262 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.026
Human
regulation of cellular amine metabolic process GO:0033238 8 0.026
response to peptide GO:1901652 292 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
positive regulation of cell differentiation GO:0045597 217 0.026
cellular catabolic process GO:0044248 295 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
positive regulation of nucleic acid templated transcription GO:1903508 197 0.025
Human
ion transmembrane transport GO:0034220 365 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.025
Human
multicellular organism growth GO:0035264 1 0.025
rna metabolic process GO:0016070 406 0.025
Human
response to cytokine GO:0034097 215 0.024
regulation of secretion by cell GO:1903530 208 0.024
signal transduction by phosphorylation GO:0023014 144 0.024
carboxylic acid metabolic process GO:0019752 289 0.024
Rat
protein oligomerization GO:0051259 191 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
macromolecular complex subunit organization GO:0043933 339 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
Human
positive regulation of cell proliferation GO:0008284 249 0.023
response to biotic stimulus GO:0009607 226 0.023
cellular response to cytokine stimulus GO:0071345 127 0.023
cellular chemical homeostasis GO:0055082 247 0.023
negative regulation of cell death GO:0060548 229 0.023
positive regulation of gene expression GO:0010628 244 0.023
Human
cell type specific apoptotic process GO:0097285 134 0.023
neuron development GO:0048666 286 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
Human
regulation of mapk cascade GO:0043408 116 0.022
positive regulation of cellular protein metabolic process GO:0032270 167 0.022
metal ion homeostasis GO:0055065 186 0.022
growth GO:0040007 165 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
regulation of hydrolase activity GO:0051336 143 0.022
Human
carboxylic acid transport GO:0046942 115 0.022
regulation of catalytic activity GO:0050790 304 0.021
Human
positive regulation of signaling GO:0023056 270 0.021
positive regulation of protein modification process GO:0031401 142 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
organic acid metabolic process GO:0006082 292 0.021
Rat
sexual reproduction GO:0019953 148 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
homeostatic process GO:0042592 331 0.021
transcription dna templated GO:0006351 377 0.021
Human
response to wounding GO:0009611 254 0.021
regulation of cell development GO:0060284 263 0.021
positive regulation of cellular component organization GO:0051130 200 0.020
regulation of cell projection organization GO:0031344 175 0.020
nitrogen compound transport GO:0071705 229 0.020
aging GO:0007568 241 0.020
oxidation reduction process GO:0055114 304 0.020
regulation of neuron differentiation GO:0045664 208 0.020
regulation of proteasomal protein catabolic process GO:0061136 4 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.020
regulation of response to stress GO:0080134 126 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
positive regulation of nervous system development GO:0051962 178 0.019
regulation of catabolic process GO:0009894 113 0.019
cellular component assembly GO:0022607 360 0.019
regulation of hormone levels GO:0010817 187 0.019
cation transmembrane transport GO:0098655 263 0.019
organic anion transport GO:0015711 132 0.019
regulation of neuron projection development GO:0010975 161 0.019
ras protein signal transduction GO:0007265 29 0.019
response to interleukin 1 GO:0070555 55 0.019
regulation of neurogenesis GO:0050767 247 0.019
cellular response to stress GO:0033554 269 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
Human
protein catabolic process GO:0030163 30 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
Human
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
regulation of protein kinase activity GO:0045859 105 0.018
neuron death GO:0070997 127 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
negative regulation of catalytic activity GO:0043086 103 0.018
Human
positive regulation of programmed cell death GO:0043068 157 0.018
protein complex biogenesis GO:0070271 263 0.018
negative regulation of signaling GO:0023057 157 0.018
response to hypoxia GO:0001666 231 0.018
central nervous system development GO:0007417 311 0.018
regulation of cellular component organization GO:0051128 368 0.018
response to bacterium GO:0009617 200 0.018
positive regulation of transport GO:0051050 245 0.018
regulation of ion transport GO:0043269 245 0.017
peptidyl amino acid modification GO:0018193 126 0.017
response to nutrient levels GO:0031667 370 0.017
gastrulation GO:0007369 2 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
axis specification GO:0009798 4 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
regulation of cytokine production GO:0001817 56 0.017
lipid metabolic process GO:0006629 283 0.017
cell projection organization GO:0030030 302 0.017
mapk cascade GO:0000165 140 0.017
positive regulation of secretion GO:0051047 140 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
response to oxidative stress GO:0006979 186 0.017
gamete generation GO:0007276 124 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
response to inorganic substance GO:0010035 377 0.017
positive regulation of transferase activity GO:0051347 81 0.016
biological adhesion GO:0022610 110 0.016
heterocycle catabolic process GO:0046700 167 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
negative regulation of cell communication GO:0010648 158 0.016
positive regulation of kinase activity GO:0033674 77 0.016
peptidyl tyrosine phosphorylation GO:0018108 72 0.016
response to growth factor GO:0070848 189 0.016
single organism catabolic process GO:0044712 283 0.016
macromolecular complex assembly GO:0065003 273 0.016
positive regulation of catabolic process GO:0009896 78 0.016
prostaglandin transport GO:0015732 8 0.016
response to lipopolysaccharide GO:0032496 191 0.016
purine containing compound metabolic process GO:0072521 253 0.016
Rat
circulatory system process GO:0003013 183 0.016
response to metal ion GO:0010038 253 0.016
cellular homeostasis GO:0019725 252 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
cellular response to lipopolysaccharide GO:0071222 55 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
regulation of cytokine biosynthetic process GO:0042035 3 0.015
chemical homeostasis GO:0048878 292 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
nucleotide metabolic process GO:0009117 279 0.015
organelle organization GO:0006996 266 0.015
alternative mrna splicing via spliceosome GO:0000380 4 0.015
regeneration GO:0031099 163 0.015
positive regulation of cell death GO:0010942 184 0.015
cytokine mediated signaling pathway GO:0019221 43 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
ion homeostasis GO:0050801 212 0.015
protein complex assembly GO:0006461 263 0.015
positive regulation of cell development GO:0010720 176 0.015
immune system process GO:0002376 204 0.015
enzyme linked receptor protein signaling pathway GO:0007167 116 0.015
brain development GO:0007420 247 0.015
dna metabolic process GO:0006259 96 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
response to alkaloid GO:0043279 132 0.014
response to peptide hormone GO:0043434 278 0.014
secretion by cell GO:0032940 248 0.014
developmental process involved in reproduction GO:0003006 159 0.014
leukocyte activation GO:0045321 76 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
lipid transport GO:0006869 61 0.014
response to oxygen levels GO:0070482 265 0.014
regulation of cellular localization GO:0060341 263 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
metal ion transport GO:0030001 289 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
erbb signaling pathway GO:0038127 23 0.014
neuron projection development GO:0031175 273 0.014
cellular component movement GO:0006928 248 0.014
regulation of cellular component movement GO:0051270 150 0.014
cellular component biogenesis GO:0044085 368 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
negative regulation of biosynthetic process GO:0009890 168 0.013
head development GO:0060322 247 0.013
aromatic compound catabolic process GO:0019439 168 0.013
peptidyl tyrosine modification GO:0018212 72 0.013
regulation of response to external stimulus GO:0032101 106 0.013
macromolecule localization GO:0033036 252 0.013
immune response GO:0006955 104 0.013
positive regulation of fatty acid transport GO:2000193 9 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
response to external biotic stimulus GO:0043207 221 0.013
regulation of neuron apoptotic process GO:0043523 83 0.013
protein complex subunit organization GO:0071822 302 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
Rat
cytokine production GO:0001816 61 0.013
generation of precursor metabolites and energy GO:0006091 62 0.013
organic acid transport GO:0015849 116 0.013
regulation of cellular response to stress GO:0080135 49 0.013
regulation of neuron death GO:1901214 115 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
Human
sensory perception GO:0007600 101 0.013
inorganic ion transmembrane transport GO:0098660 229 0.012
cardiac conduction GO:0061337 2 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
regulation of anion transport GO:0044070 43 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
cellular response to oxidative stress GO:0034599 76 0.012
response to decreased oxygen levels GO:0036293 237 0.012
inflammatory response GO:0006954 150 0.012
regulation of protein serine threonine kinase activity GO:0071900 64 0.012
macromolecule catabolic process GO:0009057 58 0.012
neurological system process GO:0050877 219 0.012
cellular response to peptide GO:1901653 133 0.012
cation transport GO:0006812 382 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
developmental growth GO:0048589 100 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
Rat
muscle system process GO:0003012 115 0.012
proteolysis GO:0006508 175 0.012
axon development GO:0061564 96 0.012
monocarboxylic acid transport GO:0015718 52 0.012
locomotion GO:0040011 237 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
regulation of growth GO:0040008 105 0.011
heart process GO:0003015 57 0.011
small molecule biosynthetic process GO:0044283 124 0.011
cell adhesion GO:0007155 110 0.011
cellular cation homeostasis GO:0030003 180 0.011
establishment of protein localization GO:0045184 141 0.011
muscle tissue development GO:0060537 58 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.011
Rat
adult locomotory behavior GO:0008344 4 0.011
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
Rat
signal release GO:0023061 145 0.011
wound healing GO:0042060 122 0.011
single organism cellular localization GO:1902580 102 0.011
protein heterooligomerization GO:0051291 89 0.011
cellular protein localization GO:0034613 122 0.011
regulation of system process GO:0044057 208 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
cellular lipid metabolic process GO:0044255 208 0.011
response to acid chemical GO:0001101 222 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
cellular ion homeostasis GO:0006873 184 0.011
positive regulation of immunoglobulin production GO:0002639 4 0.011
localization of cell GO:0051674 202 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
intracellular transport GO:0046907 185 0.011
single organism biosynthetic process GO:0044711 342 0.011
muscle structure development GO:0061061 87 0.011
glycogen metabolic process GO:0005977 23 0.011
striated muscle contraction GO:0006941 44 0.011
positive regulation of tolerance induction GO:0002645 1 0.011
regulation of response to wounding GO:1903034 69 0.011
hormone transport GO:0009914 121 0.011
blood circulation GO:0008015 183 0.011
response to nutrient GO:0007584 248 0.011
purine containing compound catabolic process GO:0072523 138 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
regulation of alpha beta t cell activation GO:0046634 2 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.010
heart development GO:0007507 72 0.010
purine nucleoside triphosphate catabolic process GO:0009146 122 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
neuron apoptotic process GO:0051402 88 0.010
cell cell signaling GO:0007267 335 0.010
positive regulation of signal transduction GO:0009967 175 0.010
cation homeostasis GO:0055080 195 0.010
positive regulation of apoptotic process GO:0043065 154 0.010

Ell disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
sensory system disease DOID:0050155 0 0.016
musculoskeletal system disease DOID:17 0 0.014
disease of cellular proliferation DOID:14566 0 0.013
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012