Rattus norvegicus

0 known processes

Efnb3

ephrin B3

(Aliases: ELK-L3,RGD1565678)

Efnb3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of rna biosynthetic process GO:2001141 381 0.138
intracellular signal transduction GO:0035556 314 0.102
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.100
central nervous system development GO:0007417 311 0.069
Rat
rna metabolic process GO:0016070 406 0.068
transcription dna templated GO:0006351 377 0.066
single organism catabolic process GO:0044712 283 0.066
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.065
regulation of rna metabolic process GO:0051252 391 0.063
neuron differentiation GO:0030182 368 0.060
Rat
regulation of apoptotic process GO:0042981 335 0.054
negative regulation of signaling GO:0023057 157 0.052
negative regulation of metabolic process GO:0009892 331 0.051
transcription from rna polymerase ii promoter GO:0006366 252 0.050
nucleic acid templated transcription GO:0097659 379 0.049
regulation of transcription dna templated GO:0006355 374 0.048
regulation of nucleic acid templated transcription GO:1903506 380 0.048
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.046
positive regulation of rna biosynthetic process GO:1902680 197 0.046
rna biosynthetic process GO:0032774 380 0.045
positive regulation of biosynthetic process GO:0009891 319 0.045
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.044
organophosphate metabolic process GO:0019637 370 0.044
catabolic process GO:0009056 351 0.044
positive regulation of cellular biosynthetic process GO:0031328 295 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.042
cell projection organization GO:0030030 302 0.041
Rat
negative regulation of nervous system development GO:0051961 79 0.041
nucleobase containing small molecule metabolic process GO:0055086 316 0.040
cation transmembrane transport GO:0098655 263 0.039
regulation of phosphorus metabolic process GO:0051174 349 0.039
response to corticosteroid GO:0031960 235 0.038
anatomical structure morphogenesis GO:0009653 298 0.038
Rat
positive regulation of transcription dna templated GO:0045893 197 0.037
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.037
head development GO:0060322 247 0.037
Rat
chemical homeostasis GO:0048878 292 0.037
purine nucleotide metabolic process GO:0006163 229 0.037
negative regulation of multicellular organismal process GO:0051241 203 0.036
response to acid chemical GO:0001101 222 0.036
metal ion homeostasis GO:0055065 186 0.035
cellular chemical homeostasis GO:0055082 247 0.035
cellular calcium ion homeostasis GO:0006874 160 0.034
cellular homeostasis GO:0019725 252 0.033
brain development GO:0007420 247 0.033
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
carbohydrate derivative metabolic process GO:1901135 346 0.032
regulation of cell development GO:0060284 263 0.032
positive regulation of rna metabolic process GO:0051254 203 0.031
positive regulation of phosphate metabolic process GO:0045937 262 0.031
regulation of peptide transport GO:0090087 87 0.030
aging GO:0007568 241 0.030
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
cellular response to organic cyclic compound GO:0071407 202 0.029
purine containing compound metabolic process GO:0072521 253 0.029
regulation of secretion by cell GO:1903530 208 0.029
regulation of ion transport GO:0043269 245 0.029
cellular metal ion homeostasis GO:0006875 172 0.028
reproductive process GO:0022414 372 0.028
multicellular organismal reproductive process GO:0048609 233 0.027
single organism biosynthetic process GO:0044711 342 0.027
organic substance catabolic process GO:1901575 316 0.027
response to glucocorticoid GO:0051384 223 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
cellular response to lipid GO:0071396 201 0.026
negative regulation of biosynthetic process GO:0009890 168 0.026
protein oligomerization GO:0051259 191 0.025
amine metabolic process GO:0009308 38 0.025
cation transport GO:0006812 382 0.025
small gtpase mediated signal transduction GO:0007264 36 0.025
negative regulation of response to stimulus GO:0048585 155 0.025
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.025
homeostatic process GO:0042592 331 0.024
cytosolic calcium ion homeostasis GO:0051480 140 0.024
regulation of cellular localization GO:0060341 263 0.024
cellular divalent inorganic cation homeostasis GO:0072503 162 0.024
programmed cell death GO:0012501 392 0.024
cellular component assembly GO:0022607 360 0.024
apoptotic process GO:0006915 381 0.024
calcium ion homeostasis GO:0055074 162 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
neuron projection development GO:0031175 273 0.024
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.023
cellular response to stress GO:0033554 269 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
regulation of molecular function GO:0065009 398 0.023
defense response GO:0006952 194 0.023
response to estradiol GO:0032355 164 0.023
ras protein signal transduction GO:0007265 29 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
cellular response to hormone stimulus GO:0032870 247 0.023
negative regulation of gene expression GO:0010629 199 0.023
single organism carbohydrate metabolic process GO:0044723 118 0.022
regulation of programmed cell death GO:0043067 341 0.022
single organism behavior GO:0044708 130 0.022
protein phosphorylation GO:0006468 345 0.022
negative regulation of cell communication GO:0010648 158 0.022
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
positive regulation of gene expression GO:0010628 244 0.022
organic hydroxy compound metabolic process GO:1901615 115 0.021
regulation of phosphate metabolic process GO:0019220 349 0.021
cellular amine metabolic process GO:0044106 38 0.021
neuron projection morphogenesis GO:0048812 122 0.021
Rat
positive regulation of molecular function GO:0044093 230 0.021
regulation of purine nucleotide metabolic process GO:1900542 115 0.021
ribonucleotide metabolic process GO:0009259 231 0.021
regulation of signal transduction GO:0009966 318 0.020
response to inorganic substance GO:0010035 377 0.020
ion homeostasis GO:0050801 212 0.020
protein complex subunit organization GO:0071822 302 0.020
actin filament based process GO:0030029 86 0.020
organelle organization GO:0006996 266 0.020
regulation of catalytic activity GO:0050790 304 0.020
divalent metal ion transport GO:0070838 132 0.020
regulation of phosphorylation GO:0042325 248 0.020
cell projection morphogenesis GO:0048858 123 0.019
Rat
organic cyclic compound catabolic process GO:1901361 175 0.019
positive regulation of protein modification process GO:0031401 142 0.019
regulation of cell differentiation GO:0045595 320 0.019
heart contraction GO:0060047 57 0.019
transmembrane transport GO:0055085 412 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
calcium ion transport GO:0006816 131 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.019
response to oxidative stress GO:0006979 186 0.019
peptide secretion GO:0002790 86 0.018
cellular catabolic process GO:0044248 295 0.018
response to retinoic acid GO:0032526 63 0.018
regulation of membrane potential GO:0042391 110 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
cellular component movement GO:0006928 248 0.018
Rat
response to ketone GO:1901654 182 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
response to ethanol GO:0045471 162 0.018
organic acid metabolic process GO:0006082 292 0.018
regulation of anatomical structure size GO:0090066 135 0.018
regulation of nervous system development GO:0051960 264 0.017
regulation of neuron differentiation GO:0045664 208 0.017
peptide transport GO:0015833 97 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
chemosensory behavior GO:0007635 2 0.017
response to metal ion GO:0010038 253 0.017
nitrogen compound transport GO:0071705 229 0.017
divalent inorganic cation transport GO:0072511 134 0.017
single organism reproductive process GO:0044702 297 0.017
organic acid transport GO:0015849 116 0.017
carboxylic acid transport GO:0046942 115 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
macromolecular complex assembly GO:0065003 273 0.017
cardiac chamber development GO:0003205 1 0.017
response to oxygen levels GO:0070482 265 0.017
regulation of cellular component organization GO:0051128 368 0.017
blood circulation GO:0008015 183 0.016
sexual reproduction GO:0019953 148 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
muscle system process GO:0003012 115 0.016
metal ion transport GO:0030001 289 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
cellular component biogenesis GO:0044085 368 0.016
inorganic cation transmembrane transport GO:0098662 202 0.016
hormone transport GO:0009914 121 0.016
cellular ion homeostasis GO:0006873 184 0.016
maintenance of location GO:0051235 17 0.016
carbohydrate homeostasis GO:0033500 75 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
neurological system process GO:0050877 219 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
response to extracellular stimulus GO:0009991 380 0.016
heart process GO:0003015 57 0.016
regulation of cell projection organization GO:0031344 175 0.016
cellular component morphogenesis GO:0032989 155 0.016
Rat
negative regulation of neuron differentiation GO:0045665 62 0.016
nucleoside metabolic process GO:0009116 179 0.016
cellular cation homeostasis GO:0030003 180 0.016
secretion GO:0046903 307 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
protein localization GO:0008104 191 0.015
synaptic transmission GO:0007268 235 0.015
tissue development GO:0009888 252 0.015
erk1 and erk2 cascade GO:0070371 48 0.015
negative regulation of neurogenesis GO:0050768 78 0.015
regulation of metal ion transport GO:0010959 118 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
regulation of peptide hormone secretion GO:0090276 80 0.015
behavior GO:0007610 205 0.015
cation homeostasis GO:0055080 195 0.015
multicellular organism reproduction GO:0032504 233 0.015
heart morphogenesis GO:0003007 3 0.015
multi organism reproductive process GO:0044703 262 0.014
negative regulation of cell development GO:0010721 82 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
oxoacid metabolic process GO:0043436 290 0.014
intracellular transport GO:0046907 185 0.014
hormone secretion GO:0046879 115 0.014
nucleotide metabolic process GO:0009117 279 0.014
negative regulation of secretion by cell GO:1903531 72 0.014
cell cell signaling GO:0007267 335 0.014
purine nucleoside catabolic process GO:0006152 124 0.014
positive regulation of cellular catabolic process GO:0031331 71 0.014
regulation of calcium ion transport GO:0051924 77 0.014
cell type specific apoptotic process GO:0097285 134 0.014
dephosphorylation GO:0016311 98 0.014
reproduction GO:0000003 245 0.014
ion transmembrane transport GO:0034220 365 0.014
positive regulation of secretion GO:0051047 140 0.014
negative regulation of phosphorus metabolic process GO:0010563 80 0.014
regulation of catabolic process GO:0009894 113 0.014
negative regulation of secretion GO:0051048 82 0.014
negative regulation of transport GO:0051051 136 0.014
neuron development GO:0048666 286 0.014
Rat
regulation of multicellular organismal development GO:2000026 376 0.014
axis specification GO:0009798 4 0.014
anterior posterior pattern specification GO:0009952 1 0.014
regulation of peptide secretion GO:0002791 82 0.014
sequestering of metal ion GO:0051238 9 0.014
anion transport GO:0006820 178 0.013
embryonic pattern specification GO:0009880 1 0.013
positive regulation of signal transduction GO:0009967 175 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
response to glucose GO:0009749 136 0.013
protein complex biogenesis GO:0070271 263 0.013
response to purine containing compound GO:0014074 126 0.013
regulation of insulin secretion GO:0050796 65 0.013
circulatory system process GO:0003013 183 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
regulation of neurogenesis GO:0050767 247 0.013
regulation of fat cell differentiation GO:0045598 3 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
single organism intracellular transport GO:1902582 166 0.013
peptide hormone secretion GO:0030072 84 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
spermatogenesis GO:0007283 99 0.013
gamete generation GO:0007276 124 0.013
ribonucleotide biosynthetic process GO:0009260 85 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
glucose homeostasis GO:0042593 75 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
response to carbohydrate GO:0009743 183 0.013
regulation of secretion GO:0051046 224 0.013
organic anion transport GO:0015711 132 0.013
sensory perception GO:0007600 101 0.013
regulation of synaptic transmission GO:0050804 141 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
ribose phosphate biosynthetic process GO:0046390 87 0.012
regulation of protein metabolic process GO:0051246 289 0.012
response to decreased oxygen levels GO:0036293 237 0.012
secretion by cell GO:0032940 248 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
regulation of neuron projection development GO:0010975 161 0.012
axon development GO:0061564 96 0.012
Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
heart development GO:0007507 72 0.012
negative regulation of signal transduction GO:0009968 83 0.012
cell morphogenesis GO:0000902 142 0.012
Rat
nucleotide biosynthetic process GO:0009165 98 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
sequestering of calcium ion GO:0051208 8 0.012
purine ribonucleotide biosynthetic process GO:0009152 81 0.012
response to organophosphorus GO:0046683 102 0.012
cell cycle GO:0007049 101 0.012
carbohydrate metabolic process GO:0005975 130 0.012
cytoplasmic transport GO:0016482 115 0.012
muscle contraction GO:0006936 88 0.012
spindle organization GO:0007051 2 0.012
gland development GO:0048732 155 0.012
amide transport GO:0042886 105 0.012
purine nucleotide catabolic process GO:0006195 136 0.011
olfactory behavior GO:0042048 2 0.011
cellular ketone metabolic process GO:0042180 51 0.011
developmental growth GO:0048589 100 0.011
bmp signaling pathway GO:0030509 4 0.011
heterocycle catabolic process GO:0046700 167 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
protein homooligomerization GO:0051260 91 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
negative regulation of molecular function GO:0044092 133 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
locomotion GO:0040011 237 0.011
Rat
action potential GO:0001508 54 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
mapk cascade GO:0000165 140 0.011
regulation of hormone secretion GO:0046883 106 0.011
cognition GO:0050890 92 0.011
positive regulation of cell communication GO:0010647 271 0.011
response to nutrient levels GO:0031667 370 0.011
circulatory system development GO:0072359 134 0.011
negative regulation of developmental process GO:0051093 125 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
forebrain development GO:0030900 98 0.011
Rat
cardiovascular system development GO:0072358 134 0.011
regulation of ion homeostasis GO:2000021 63 0.011
nucleotide catabolic process GO:0009166 139 0.011
exploration behavior GO:0035640 1 0.011
cell cycle checkpoint GO:0000075 2 0.011
cardiac conduction GO:0061337 2 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
male gamete generation GO:0048232 99 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
regulation of establishment of planar polarity GO:0090175 2 0.011
dna metabolic process GO:0006259 96 0.011
regulation of meiotic cell cycle GO:0051445 3 0.011
establishment of tissue polarity GO:0007164 2 0.010
regulation of protein modification process GO:0031399 194 0.010
regulation of blood pressure GO:0008217 83 0.010
positive regulation of catalytic activity GO:0043085 184 0.010
positive regulation of developmental process GO:0051094 283 0.010
regulation of mapk cascade GO:0043408 116 0.010
response to estrogen GO:0043627 232 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010
regulation of cellular protein metabolic process GO:0032268 267 0.010
developmental growth involved in morphogenesis GO:0060560 33 0.010
adult locomotory behavior GO:0008344 4 0.010
positive regulation of neurogenesis GO:0050769 165 0.010
inflammatory response GO:0006954 150 0.010
positive regulation of hydrolase activity GO:0051345 86 0.010
positive regulation of cell proliferation GO:0008284 249 0.010
negative regulation of cell death GO:0060548 229 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
regulation of cellular ketone metabolic process GO:0010565 27 0.010
response to hypoxia GO:0001666 231 0.010

Efnb3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.014
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012
nervous system disease DOID:863 0 0.012
disease of metabolism DOID:0014667 0 0.011