Rattus norvegicus

0 known processes

Cys1

cystin 1

Cys1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
metal ion transport GO:0030001 289 0.065
response to inorganic substance GO:0010035 377 0.060
transmembrane transport GO:0055085 412 0.059
cation transport GO:0006812 382 0.057
intracellular signal transduction GO:0035556 314 0.054
programmed cell death GO:0012501 392 0.053
cellular component biogenesis GO:0044085 368 0.052
cellular response to oxygen containing compound GO:1901701 386 0.051
response to extracellular stimulus GO:0009991 380 0.051
regulation of nucleic acid templated transcription GO:1903506 380 0.050
inorganic cation transmembrane transport GO:0098662 202 0.048
apoptotic process GO:0006915 381 0.048
cation transmembrane transport GO:0098655 263 0.046
negative regulation of cellular metabolic process GO:0031324 281 0.043
neurological system process GO:0050877 219 0.042
ion transmembrane transport GO:0034220 365 0.040
nucleic acid templated transcription GO:0097659 379 0.040
response to oxygen levels GO:0070482 265 0.039
negative regulation of metabolic process GO:0009892 331 0.037
cellular response to endogenous stimulus GO:0071495 377 0.036
positive regulation of phosphorus metabolic process GO:0010562 262 0.035
cell cell signaling GO:0007267 335 0.034
regulation of programmed cell death GO:0043067 341 0.034
regulation of rna metabolic process GO:0051252 391 0.034
cellular component assembly GO:0022607 360 0.032
regulation of molecular function GO:0065009 398 0.032
homeostatic process GO:0042592 331 0.032
inorganic ion transmembrane transport GO:0098660 229 0.031
cellular response to stress GO:0033554 269 0.030
organic acid metabolic process GO:0006082 292 0.030
cellular ion homeostasis GO:0006873 184 0.030
regulation of cell proliferation GO:0042127 359 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.029
cell projection organization GO:0030030 302 0.029
response to wounding GO:0009611 254 0.028
protein complex subunit organization GO:0071822 302 0.028
response to nutrient levels GO:0031667 370 0.028
transcription dna templated GO:0006351 377 0.027
rna biosynthetic process GO:0032774 380 0.027
g protein coupled receptor signaling pathway GO:0007186 242 0.027
regulation of apoptotic process GO:0042981 335 0.027
regulation of phosphorylation GO:0042325 248 0.027
divalent metal ion transport GO:0070838 132 0.027
regulation of ion transport GO:0043269 245 0.027
divalent inorganic cation transport GO:0072511 134 0.027
central nervous system development GO:0007417 311 0.027
protein complex assembly GO:0006461 263 0.027
cell type specific apoptotic process GO:0097285 134 0.026
regulation of intracellular signal transduction GO:1902531 218 0.026
cellular ketone metabolic process GO:0042180 51 0.026
response to decreased oxygen levels GO:0036293 237 0.026
positive regulation of transport GO:0051050 245 0.026
cellular metal ion homeostasis GO:0006875 172 0.025
regulation of cell differentiation GO:0045595 320 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
cellular amine metabolic process GO:0044106 38 0.025
reproductive process GO:0022414 372 0.024
cellular homeostasis GO:0019725 252 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
ion homeostasis GO:0050801 212 0.024
response to oxidative stress GO:0006979 186 0.024
positive regulation of cell proliferation GO:0008284 249 0.024
regulation of protein metabolic process GO:0051246 289 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
neuron projection development GO:0031175 273 0.024
macromolecular complex assembly GO:0065003 273 0.024
protein complex biogenesis GO:0070271 263 0.024
negative regulation of signaling GO:0023057 157 0.023
response to nutrient GO:0007584 248 0.023
response to hypoxia GO:0001666 231 0.023
cellular chemical homeostasis GO:0055082 247 0.023
amine metabolic process GO:0009308 38 0.023
regulation of neurogenesis GO:0050767 247 0.023
protein phosphorylation GO:0006468 345 0.023
regulation of cellular component organization GO:0051128 368 0.022
macromolecular complex subunit organization GO:0043933 339 0.022
secretion GO:0046903 307 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
positive regulation of molecular function GO:0044093 230 0.022
metal ion homeostasis GO:0055065 186 0.022
regulation of metal ion transport GO:0010959 118 0.022
calcium ion transport GO:0006816 131 0.022
cellular response to lipid GO:0071396 201 0.022
macromolecule localization GO:0033036 252 0.021
regulation of immune system process GO:0002682 123 0.021
tissue development GO:0009888 252 0.021
response to acid chemical GO:0001101 222 0.021
heart morphogenesis GO:0003007 3 0.021
regulation of transcription dna templated GO:0006355 374 0.021
single organism biosynthetic process GO:0044711 342 0.021
positive regulation of developmental process GO:0051094 283 0.021
catabolic process GO:0009056 351 0.021
response to growth factor GO:0070848 189 0.021
neuron differentiation GO:0030182 368 0.020
cell part morphogenesis GO:0032990 123 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
neuron development GO:0048666 286 0.020
regulation of signal transduction GO:0009966 318 0.020
cellular amino acid metabolic process GO:0006520 107 0.020
anatomical structure morphogenesis GO:0009653 298 0.020
regulation of phosphate metabolic process GO:0019220 349 0.020
positive regulation of cell death GO:0010942 184 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
anion transport GO:0006820 178 0.020
developmental growth GO:0048589 100 0.020
chemical homeostasis GO:0048878 292 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
cellular response to growth factor stimulus GO:0071363 162 0.019
monovalent inorganic cation transport GO:0015672 172 0.019
organelle organization GO:0006996 266 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
intracellular transport GO:0046907 185 0.019
behavior GO:0007610 205 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
cation homeostasis GO:0055080 195 0.019
positive regulation of signaling GO:0023056 270 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
cellular cation homeostasis GO:0030003 180 0.019
regulation of anatomical structure size GO:0090066 135 0.019
carboxylic acid metabolic process GO:0019752 289 0.019
positive regulation of ion transport GO:0043270 94 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.019
regulation of protein modification process GO:0031399 194 0.019
response to hydrogen peroxide GO:0042542 89 0.019
cell morphogenesis GO:0000902 142 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
regulation of cell motility GO:2000145 131 0.019
response to corticosteroid GO:0031960 235 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
rhythmic process GO:0048511 156 0.019
regulation of system process GO:0044057 208 0.019
regulation of cellular localization GO:0060341 263 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
single organism catabolic process GO:0044712 283 0.018
cellular component movement GO:0006928 248 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
cellular component morphogenesis GO:0032989 155 0.018
cell motility GO:0048870 202 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
nucleotide metabolic process GO:0009117 279 0.018
regulation of catalytic activity GO:0050790 304 0.018
cellular calcium ion homeostasis GO:0006874 160 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
negative regulation of gene expression GO:0010629 199 0.017
negative regulation of cell communication GO:0010648 158 0.017
regulation of neuron differentiation GO:0045664 208 0.017
organophosphate metabolic process GO:0019637 370 0.017
multicellular organism reproduction GO:0032504 233 0.017
purine containing compound metabolic process GO:0072521 253 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
ras protein signal transduction GO:0007265 29 0.017
growth GO:0040007 165 0.017
response to estrogen GO:0043627 232 0.017
regulation of cell projection organization GO:0031344 175 0.017
rna metabolic process GO:0016070 406 0.017
reproduction GO:0000003 245 0.017
response to metal ion GO:0010038 253 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
response to reactive oxygen species GO:0000302 120 0.017
regulation of cell development GO:0060284 263 0.016
response to peptide hormone GO:0043434 278 0.016
positive regulation of intracellular signal transduction GO:1902533 138 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
response to radiation GO:0009314 137 0.016
protein oligomerization GO:0051259 191 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
regulation of neuron projection development GO:0010975 161 0.016
oxoacid metabolic process GO:0043436 290 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
regulation of nervous system development GO:0051960 264 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
positive regulation of cell communication GO:0010647 271 0.016
head development GO:0060322 247 0.016
cell migration GO:0016477 197 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
single organism reproductive process GO:0044702 297 0.015
neuron apoptotic process GO:0051402 88 0.015
cellular catabolic process GO:0044248 295 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
negative regulation of molecular function GO:0044092 133 0.015
brain development GO:0007420 247 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
cellular response to peptide GO:1901653 133 0.015
negative regulation of cell death GO:0060548 229 0.015
response to biotic stimulus GO:0009607 226 0.015
reproductive structure development GO:0048608 128 0.014
response to carbohydrate GO:0009743 183 0.014
immune system process GO:0002376 204 0.014
muscle contraction GO:0006936 88 0.014
positive regulation of protein modification process GO:0031401 142 0.014
multi organism reproductive process GO:0044703 262 0.014
regulation of secretion by cell GO:1903530 208 0.014
organic substance catabolic process GO:1901575 316 0.014
protein localization GO:0008104 191 0.014
single organism intracellular transport GO:1902582 166 0.014
nitrogen compound transport GO:0071705 229 0.014
regulation of hydrolase activity GO:0051336 143 0.014
regulation of response to external stimulus GO:0032101 106 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
mapk cascade GO:0000165 140 0.014
eye morphogenesis GO:0048592 4 0.014
positive regulation of nervous system development GO:0051962 178 0.014
response to vitamin GO:0033273 131 0.014
development of primary sexual characteristics GO:0045137 107 0.013
mesoderm development GO:0007498 2 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
response to mechanical stimulus GO:0009612 134 0.013
regulation of cell migration GO:0030334 128 0.013
gastrulation GO:0007369 2 0.013
response to monosaccharide GO:0034284 159 0.013
cellular response to acid chemical GO:0071229 75 0.013
negative regulation of transport GO:0051051 136 0.013
axis specification GO:0009798 4 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
regulation of locomotion GO:0040012 148 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
developmental process involved in reproduction GO:0003006 159 0.013
neuron death GO:0070997 127 0.013
cell projection morphogenesis GO:0048858 123 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
reproductive system development GO:0061458 128 0.013
positive regulation of gene expression GO:0010628 244 0.013
response to ethanol GO:0045471 162 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
cell growth GO:0016049 104 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
blood circulation GO:0008015 183 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
response to ketone GO:1901654 182 0.013
regulation of proteasomal protein catabolic process GO:0061136 4 0.013
regulation of neuron apoptotic process GO:0043523 83 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
response to peptide GO:1901652 292 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
aging GO:0007568 241 0.013
cytoplasmic transport GO:0016482 115 0.012
cellular macromolecule localization GO:0070727 122 0.012
regulation of calcium ion transport GO:0051924 77 0.012
regulation of transmembrane transport GO:0034762 122 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
regulation of kinase activity GO:0043549 117 0.012
response to alkaloid GO:0043279 132 0.012
regeneration GO:0031099 163 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
cardiovascular system development GO:0072358 134 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
calcium ion homeostasis GO:0055074 162 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
cellular protein localization GO:0034613 122 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
response to increased oxygen levels GO:0036296 45 0.012
cellular response to external stimulus GO:0071496 118 0.012
circulatory system development GO:0072359 134 0.012
establishment of protein localization GO:0045184 141 0.012
potassium ion transport GO:0006813 97 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
regulation of secretion GO:0051046 224 0.012
oxidation reduction process GO:0055114 304 0.012
negative regulation of developmental process GO:0051093 125 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
multi multicellular organism process GO:0044706 138 0.012
negative regulation of apoptotic process GO:0043066 181 0.011
organic anion transport GO:0015711 132 0.011
adult locomotory behavior GO:0008344 4 0.011
signal release GO:0023061 145 0.011
positive regulation of cell development GO:0010720 176 0.011
response to cytokine GO:0034097 215 0.011
regulation of blood circulation GO:1903522 110 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
regulation of tube size GO:0035150 89 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
sexual reproduction GO:0019953 148 0.011
sequestering of calcium ion GO:0051208 8 0.011
sex differentiation GO:0007548 113 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
synaptic transmission GO:0007268 235 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
cardiac chamber development GO:0003205 1 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
sequestering of metal ion GO:0051238 9 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
nucleoside metabolic process GO:0009116 179 0.011
carbohydrate metabolic process GO:0005975 130 0.011
calcium ion transmembrane transport GO:0070588 70 0.011
neural crest cell development GO:0014032 2 0.011
regulation of transferase activity GO:0051338 123 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
biological adhesion GO:0022610 110 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
formation of primary germ layer GO:0001704 1 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
regulation of body fluid levels GO:0050878 90 0.010
regulation of protein kinase activity GO:0045859 105 0.010
wound healing GO:0042060 122 0.010
sensory perception of pain GO:0019233 73 0.010
localization of cell GO:0051674 202 0.010
regulation of blood vessel size GO:0050880 89 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
regulation of mapk cascade GO:0043408 116 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
response to retinoic acid GO:0032526 63 0.010
positive regulation of cellular biosynthetic process GO:0031328 295 0.010
peptide secretion GO:0002790 86 0.010
response to glucose GO:0009749 136 0.010
proteolysis GO:0006508 175 0.010
multicellular organism growth GO:0035264 1 0.010
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
regulation of membrane potential GO:0042391 110 0.010
muscle system process GO:0003012 115 0.010
positive regulation of signal transduction GO:0009967 175 0.010
regulation of cellular component movement GO:0051270 150 0.010
signal transduction by phosphorylation GO:0023014 144 0.010
cellular response to oxidative stress GO:0034599 76 0.010
synaptic growth at neuromuscular junction GO:0051124 1 0.010
aromatic compound catabolic process GO:0019439 168 0.010
regulation of catabolic process GO:0009894 113 0.010

Cys1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
nervous system disease DOID:863 0 0.053
sensory system disease DOID:0050155 0 0.021
musculoskeletal system disease DOID:17 0 0.021
central nervous system disease DOID:331 0 0.018
myopathy DOID:423 0 0.013
muscular disease DOID:0080000 0 0.013
muscle tissue disease DOID:66 0 0.013
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.011
brain disease DOID:936 0 0.010