Rattus norvegicus

0 known processes

Mppe1

metallophosphoesterase 1

Mppe1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
intracellular signal transduction GO:0035556 314 0.080
rna metabolic process GO:0016070 406 0.075
rna biosynthetic process GO:0032774 380 0.072
lipid metabolic process GO:0006629 283 0.062
regulation of rna metabolic process GO:0051252 391 0.054
regulation of molecular function GO:0065009 398 0.050
organic acid metabolic process GO:0006082 292 0.049
regulation of programmed cell death GO:0043067 341 0.047
regulation of phosphorus metabolic process GO:0051174 349 0.045
protein phosphorylation GO:0006468 345 0.045
regulation of catalytic activity GO:0050790 304 0.043
regulation of multicellular organismal development GO:2000026 376 0.042
apoptotic process GO:0006915 381 0.042
negative regulation of cell death GO:0060548 229 0.042
negative regulation of metabolic process GO:0009892 331 0.041
regulation of cell proliferation GO:0042127 359 0.040
regulation of cellular protein metabolic process GO:0032268 267 0.039
cellular lipid metabolic process GO:0044255 208 0.038
oxoacid metabolic process GO:0043436 290 0.038
regulation of cellular ketone metabolic process GO:0010565 27 0.037
regulation of cell differentiation GO:0045595 320 0.037
regulation of intracellular signal transduction GO:1902531 218 0.037
positive regulation of response to stimulus GO:0048584 285 0.035
cellular component assembly GO:0022607 360 0.035
positive regulation of phosphorus metabolic process GO:0010562 262 0.035
nitrogen compound transport GO:0071705 229 0.034
regulation of phosphate metabolic process GO:0019220 349 0.034
regulation of rna biosynthetic process GO:2001141 381 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
response to nutrient levels GO:0031667 370 0.032
regulation of apoptotic process GO:0042981 335 0.032
organic acid transport GO:0015849 116 0.032
regulation of protein modification process GO:0031399 194 0.031
cellular amine metabolic process GO:0044106 38 0.031
carboxylic acid metabolic process GO:0019752 289 0.031
regulation of signal transduction GO:0009966 318 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.029
transcription dna templated GO:0006351 377 0.029
positive regulation of signal transduction GO:0009967 175 0.029
positive regulation of signaling GO:0023056 270 0.029
organophosphate biosynthetic process GO:0090407 143 0.029
regulation of protein phosphorylation GO:0001932 183 0.028
response to acid chemical GO:0001101 222 0.028
anion transport GO:0006820 178 0.028
cellular response to organic cyclic compound GO:0071407 202 0.028
single organism biosynthetic process GO:0044711 342 0.028
positive regulation of phosphate metabolic process GO:0045937 262 0.028
carboxylic acid transport GO:0046942 115 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
programmed cell death GO:0012501 392 0.028
cellular ketone metabolic process GO:0042180 51 0.027
protein complex biogenesis GO:0070271 263 0.027
positive regulation of molecular function GO:0044093 230 0.027
positive regulation of cell proliferation GO:0008284 249 0.026
organic anion transport GO:0015711 132 0.026
organic substance catabolic process GO:1901575 316 0.026
central nervous system development GO:0007417 311 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
homeostatic process GO:0042592 331 0.026
negative regulation of gene expression GO:0010629 199 0.026
response to extracellular stimulus GO:0009991 380 0.025
cellular component biogenesis GO:0044085 368 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
nucleic acid templated transcription GO:0097659 379 0.025
positive regulation of cellular protein metabolic process GO:0032270 167 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
regulation of phosphorylation GO:0042325 248 0.024
positive regulation of catalytic activity GO:0043085 184 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
response to metal ion GO:0010038 253 0.024
regulation of transcription dna templated GO:0006355 374 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
response to growth factor GO:0070848 189 0.023
cellular homeostasis GO:0019725 252 0.023
mapk cascade GO:0000165 140 0.023
amine metabolic process GO:0009308 38 0.023
negative regulation of cell communication GO:0010648 158 0.023
regulation of protein metabolic process GO:0051246 289 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
positive regulation of protein phosphorylation GO:0001934 135 0.023
positive regulation of developmental process GO:0051094 283 0.022
monocarboxylic acid metabolic process GO:0032787 152 0.022
single organism intracellular transport GO:1902582 166 0.022
transcription from rna polymerase ii promoter GO:0006366 252 0.022
negative regulation of apoptotic process GO:0043066 181 0.021
brain development GO:0007420 247 0.021
transmembrane transport GO:0055085 412 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
oligopeptide transport GO:0006857 4 0.021
positive regulation of cell communication GO:0010647 271 0.021
protein oligomerization GO:0051259 191 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
chemical homeostasis GO:0048878 292 0.020
response to inorganic substance GO:0010035 377 0.020
regulation of transferase activity GO:0051338 123 0.020
regulation of cellular component organization GO:0051128 368 0.020
secretion GO:0046903 307 0.020
multicellular organism growth GO:0035264 1 0.020
intracellular transport GO:0046907 185 0.020
amide transport GO:0042886 105 0.019
protein complex assembly GO:0006461 263 0.019
protein localization GO:0008104 191 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
protein complex subunit organization GO:0071822 302 0.019
cellular protein localization GO:0034613 122 0.019
multi organism reproductive process GO:0044703 262 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
neuron differentiation GO:0030182 368 0.019
cation homeostasis GO:0055080 195 0.019
regulation of cellular localization GO:0060341 263 0.019
response to peptide hormone GO:0043434 278 0.019
cellular response to stress GO:0033554 269 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.019
reproductive process GO:0022414 372 0.019
regulation of hormone levels GO:0010817 187 0.019
cytoplasmic transport GO:0016482 115 0.019
neuron projection development GO:0031175 273 0.019
regulation of secretion GO:0051046 224 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
macromolecular complex assembly GO:0065003 273 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
amino acid transport GO:0006865 70 0.018
monocarboxylic acid transport GO:0015718 52 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
cellular response to lipid GO:0071396 201 0.018
negative regulation of signaling GO:0023057 157 0.018
ion transmembrane transport GO:0034220 365 0.018
nucleotide metabolic process GO:0009117 279 0.018
response to nutrient GO:0007584 248 0.018
organophosphate metabolic process GO:0019637 370 0.018
lipid biosynthetic process GO:0008610 128 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
regulation of cell development GO:0060284 263 0.018
negative regulation of rna metabolic process GO:0051253 123 0.018
positive regulation of biosynthetic process GO:0009891 319 0.017
organelle organization GO:0006996 266 0.017
purine containing compound metabolic process GO:0072521 253 0.017
multicellular organism reproduction GO:0032504 233 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
glutathione transport GO:0034635 2 0.017
cell projection organization GO:0030030 302 0.017
macromolecule localization GO:0033036 252 0.017
response to corticosteroid GO:0031960 235 0.017
negative regulation of developmental process GO:0051093 125 0.017
regulation of mapk cascade GO:0043408 116 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
regulation of nervous system development GO:0051960 264 0.016
response to insulin GO:0032868 133 0.016
organic hydroxy compound transport GO:0015850 77 0.016
cellular macromolecule localization GO:0070727 122 0.016
single organism catabolic process GO:0044712 283 0.016
proteolysis GO:0006508 175 0.016
negative regulation of molecular function GO:0044092 133 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
gastrulation GO:0007369 2 0.016
single organism reproductive process GO:0044702 297 0.016
positive regulation of nervous system development GO:0051962 178 0.016
regulation of neurogenesis GO:0050767 247 0.016
hormone transport GO:0009914 121 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
catabolic process GO:0009056 351 0.016
reproduction GO:0000003 245 0.015
secretion by cell GO:0032940 248 0.015
cellular catabolic process GO:0044248 295 0.015
dephosphorylation GO:0016311 98 0.015
positive regulation of cell death GO:0010942 184 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
positive regulation of gene expression GO:0010628 244 0.015
peptide transport GO:0015833 97 0.015
establishment of protein localization GO:0045184 141 0.015
cation transport GO:0006812 382 0.015
metal ion homeostasis GO:0055065 186 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
response to decreased oxygen levels GO:0036293 237 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
cellular component movement GO:0006928 248 0.015
head development GO:0060322 247 0.015
regulation of kinase activity GO:0043549 117 0.014
neuron development GO:0048666 286 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
adult locomotory behavior GO:0008344 4 0.014
cation transmembrane transport GO:0098655 263 0.014
regulation of secretion by cell GO:1903530 208 0.014
response to carbohydrate GO:0009743 183 0.014
small molecule biosynthetic process GO:0044283 124 0.014
nucleobase containing small molecule metabolic process GO:0055086 316 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
response to oxygen levels GO:0070482 265 0.014
cellular ion homeostasis GO:0006873 184 0.014
cellular amino acid metabolic process GO:0006520 107 0.014
positive regulation of protein modification process GO:0031401 142 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
negative regulation of transport GO:0051051 136 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
gland development GO:0048732 155 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
response to ethanol GO:0045471 162 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
anion transmembrane transport GO:0098656 77 0.013
ion homeostasis GO:0050801 212 0.013
carbohydrate metabolic process GO:0005975 130 0.013
ras protein signal transduction GO:0007265 29 0.013
positive regulation of transferase activity GO:0051347 81 0.013
calcium ion homeostasis GO:0055074 162 0.013
response to external biotic stimulus GO:0043207 221 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
developmental process involved in reproduction GO:0003006 159 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
response to hypoxia GO:0001666 231 0.013
response to wounding GO:0009611 254 0.013
response to vitamin GO:0033273 131 0.013
regulation of hormone secretion GO:0046883 106 0.013
nucleoside metabolic process GO:0009116 179 0.013
response to cytokine GO:0034097 215 0.013
axis specification GO:0009798 4 0.013
rhythmic process GO:0048511 156 0.013
anterior posterior pattern specification GO:0009952 1 0.013
negative regulation of cell cycle phase transition GO:1901988 4 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
response to alkaloid GO:0043279 132 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
oxidation reduction process GO:0055114 304 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
gonad development GO:0008406 104 0.012
regulation of membrane potential GO:0042391 110 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
cellular chemical homeostasis GO:0055082 247 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
regulation of neuron differentiation GO:0045664 208 0.012
cell cell signaling GO:0007267 335 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
response to peptide GO:1901652 292 0.012
regulation of neuron projection development GO:0010975 161 0.012
regulation of peptide transport GO:0090087 87 0.012
defense response GO:0006952 194 0.012
growth GO:0040007 165 0.012
response to other organism GO:0051707 220 0.012
single organism cellular localization GO:1902580 102 0.012
cellular response to endogenous stimulus GO:0071495 377 0.012
neurological system process GO:0050877 219 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
cellular cation homeostasis GO:0030003 180 0.012
response to estrogen GO:0043627 232 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
protein transport GO:0015031 132 0.011
cell cycle checkpoint GO:0000075 2 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
response to glucose GO:0009749 136 0.011
protein homooligomerization GO:0051260 91 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.011
regulation of hydrolase activity GO:0051336 143 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
regulation of protein kinase activity GO:0045859 105 0.011
positive regulation of transport GO:0051050 245 0.011
cell cycle GO:0007049 101 0.011
response to ketone GO:1901654 182 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
hormone secretion GO:0046879 115 0.011
heterocycle catabolic process GO:0046700 167 0.011
response to monosaccharide GO:0034284 159 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
sex differentiation GO:0007548 113 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
negative regulation of signal transduction GO:0009968 83 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
inflammatory response GO:0006954 150 0.011
sterol homeostasis GO:0055092 3 0.011
positive regulation of cell development GO:0010720 176 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.010
response to glucocorticoid GO:0051384 223 0.010
response to molecule of fungal origin GO:0002238 3 0.010
tissue development GO:0009888 252 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
embryonic pattern specification GO:0009880 1 0.010
phospholipid metabolic process GO:0006644 61 0.010
aromatic compound catabolic process GO:0019439 168 0.010
regulation of system process GO:0044057 208 0.010
sexual reproduction GO:0019953 148 0.010
positive regulation of neurogenesis GO:0050769 165 0.010
developmental growth GO:0048589 100 0.010
development of primary sexual characteristics GO:0045137 107 0.010
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
response to hexose GO:0009746 144 0.010
response to biotic stimulus GO:0009607 226 0.010
rho protein signal transduction GO:0007266 11 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010

Mppe1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
musculoskeletal system disease DOID:17 0 0.022
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.011
sensory system disease DOID:0050155 0 0.011
central nervous system disease DOID:331 0 0.011
connective tissue disease DOID:65 0 0.010