Rattus norvegicus

18 known processes

Eif5

eukaryotic translation initiation factor 5

Eif5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular catabolic process GO:0044248 295 0.412
regulation of cellular component organization GO:0051128 368 0.333
aromatic compound catabolic process GO:0019439 168 0.305
purine ribonucleoside catabolic process GO:0046130 124 0.287
ribonucleoside catabolic process GO:0042454 126 0.264
purine nucleotide catabolic process GO:0006195 136 0.210
anatomical structure morphogenesis GO:0009653 298 0.196
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.188
carbohydrate derivative catabolic process GO:1901136 147 0.178
nucleoside triphosphate catabolic process GO:0009143 123 0.174
catabolic process GO:0009056 351 0.174
regulation of cellular protein metabolic process GO:0032268 267 0.171
organophosphate catabolic process GO:0046434 148 0.169
response to cytokine GO:0034097 215 0.162
nucleoside phosphate catabolic process GO:1901292 140 0.148
organelle organization GO:0006996 266 0.142
vesicle mediated transport GO:0016192 181 0.139
cellular component morphogenesis GO:0032989 155 0.133
purine containing compound catabolic process GO:0072523 138 0.132
purine ribonucleotide catabolic process GO:0009154 136 0.131
ribonucleotide catabolic process GO:0009261 136 0.129
purine nucleoside triphosphate catabolic process GO:0009146 122 0.125
macromolecule localization GO:0033036 252 0.123
nucleobase containing compound catabolic process GO:0034655 152 0.121
ribonucleoside triphosphate metabolic process GO:0009199 141 0.118
organic substance catabolic process GO:1901575 316 0.113
reproduction GO:0000003 245 0.113
purine nucleoside metabolic process GO:0042278 169 0.111
organonitrogen compound catabolic process GO:1901565 179 0.111
macromolecular complex subunit organization GO:0043933 339 0.110
ribonucleotide metabolic process GO:0009259 231 0.107
nucleoside metabolic process GO:0009116 179 0.104
cellular nitrogen compound catabolic process GO:0044270 163 0.102
nucleoside catabolic process GO:0009164 126 0.102
regulation of catalytic activity GO:0050790 304 0.102
glycosyl compound catabolic process GO:1901658 126 0.097
nucleotide catabolic process GO:0009166 139 0.095
purine nucleoside catabolic process GO:0006152 124 0.095
ribonucleoside triphosphate catabolic process GO:0009203 122 0.094
establishment of protein localization GO:0045184 141 0.093
ribonucleoside metabolic process GO:0009119 174 0.088
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.086
heterocycle catabolic process GO:0046700 167 0.085
small gtpase mediated signal transduction GO:0007264 36 0.084
regulation of protein metabolic process GO:0051246 289 0.080
nucleoside triphosphate metabolic process GO:0009141 144 0.079
purine ribonucleoside metabolic process GO:0046128 168 0.079
protein transport GO:0015031 132 0.079
organophosphate metabolic process GO:0019637 370 0.076
protein localization GO:0008104 191 0.069
multicellular organismal reproductive process GO:0048609 233 0.068
nucleotide metabolic process GO:0009117 279 0.068
nucleoside phosphate metabolic process GO:0006753 283 0.067
regulation of signal transduction GO:0009966 318 0.066
purine ribonucleotide metabolic process GO:0009150 227 0.066
cellular component assembly GO:0022607 360 0.065
nucleoside monophosphate catabolic process GO:0009125 56 0.065
protein complex assembly GO:0006461 263 0.064
sexual reproduction GO:0019953 148 0.060
dna metabolic process GO:0006259 96 0.060
glycosyl compound metabolic process GO:1901657 182 0.058
atp catabolic process GO:0006200 54 0.058
guanosine containing compound catabolic process GO:1901069 71 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.055
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.054
dendrite development GO:0016358 72 0.053
purine nucleoside triphosphate metabolic process GO:0009144 141 0.052
ribose phosphate metabolic process GO:0019693 235 0.051
positive regulation of cellular component organization GO:0051130 200 0.051
purine nucleotide metabolic process GO:0006163 229 0.049
regulation of cellular response to stress GO:0080135 49 0.049
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.049
single organism catabolic process GO:0044712 283 0.049
regulation of hydrolase activity GO:0051336 143 0.047
ras protein signal transduction GO:0007265 29 0.047
positive regulation of cellular biosynthetic process GO:0031328 295 0.046
purine containing compound metabolic process GO:0072521 253 0.046
protein phosphorylation GO:0006468 345 0.045
programmed cell death GO:0012501 392 0.045
metal ion transport GO:0030001 289 0.044
guanosine containing compound metabolic process GO:1901068 74 0.044
gtp catabolic process GO:0006184 71 0.044
carbohydrate derivative metabolic process GO:1901135 346 0.043
organic cyclic compound catabolic process GO:1901361 175 0.043
cellular protein localization GO:0034613 122 0.042
nucleic acid templated transcription GO:0097659 379 0.042
cell projection organization GO:0030030 302 0.041
regulation of cellular localization GO:0060341 263 0.041
gtp metabolic process GO:0046039 72 0.040
regulation of catabolic process GO:0009894 113 0.040
regulation of cellular catabolic process GO:0031329 101 0.039
regulation of apoptotic process GO:0042981 335 0.039
response to nutrient levels GO:0031667 370 0.038
regulation of nucleotide metabolic process GO:0006140 117 0.038
positive regulation of protein metabolic process GO:0051247 178 0.037
neuron differentiation GO:0030182 368 0.037
cellular response to cytokine stimulus GO:0071345 127 0.037
regulation of phosphate metabolic process GO:0019220 349 0.037
regulation of phosphorus metabolic process GO:0051174 349 0.037
intracellular protein transport GO:0006886 79 0.036
positive regulation of biosynthetic process GO:0009891 319 0.036
acrosome assembly GO:0001675 3 0.035
rna metabolic process GO:0016070 406 0.035
regulation of cell projection organization GO:0031344 175 0.035
cellular component biogenesis GO:0044085 368 0.034
single organism intracellular transport GO:1902582 166 0.033
positive regulation of cell projection organization GO:0031346 111 0.033
negative regulation of cell communication GO:0010648 158 0.033
regulation of protein kinase activity GO:0045859 105 0.033
protein targeting GO:0006605 61 0.033
cell projection assembly GO:0030031 21 0.032
multi organism reproductive process GO:0044703 262 0.032
single organism cellular localization GO:1902580 102 0.032
neuron development GO:0048666 286 0.032
positive regulation of catabolic process GO:0009896 78 0.031
reproductive process GO:0022414 372 0.031
apoptotic process GO:0006915 381 0.031
regulation of organelle organization GO:0033043 80 0.031
negative regulation of programmed cell death GO:0043069 183 0.030
positive regulation of transcription dna templated GO:0045893 197 0.030
cellular response to endogenous stimulus GO:0071495 377 0.030
establishment of protein localization to organelle GO:0072594 44 0.030
positive regulation of developmental process GO:0051094 283 0.030
single organism organelle organization GO:1902589 180 0.029
response to extracellular stimulus GO:0009991 380 0.029
cellular macromolecule localization GO:0070727 122 0.029
cell morphogenesis involved in differentiation GO:0000904 119 0.029
multicellular organism reproduction GO:0032504 233 0.029
regulation of neuron projection development GO:0010975 161 0.028
response to external biotic stimulus GO:0043207 221 0.028
regulation of response to stress GO:0080134 126 0.028
lipid metabolic process GO:0006629 283 0.028
cation transport GO:0006812 382 0.027
response to toxic substance GO:0009636 133 0.027
regulation of cell morphogenesis GO:0022604 77 0.027
nuclear transport GO:0051169 49 0.026
macromolecular complex assembly GO:0065003 273 0.026
protein complex biogenesis GO:0070271 263 0.026
regulation of protein localization GO:0032880 81 0.026
positive regulation of protein import into nucleus translocation GO:0033160 7 0.026
regulation of protein modification process GO:0031399 194 0.026
positive regulation of gene expression GO:0010628 244 0.025
mapk cascade GO:0000165 140 0.025
gamete generation GO:0007276 124 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
neurological system process GO:0050877 219 0.023
regulation of purine nucleotide metabolic process GO:1900542 115 0.023
positive regulation of molecular function GO:0044093 230 0.023
cytokine mediated signaling pathway GO:0019221 43 0.023
regulation of phosphorylation GO:0042325 248 0.023
spindle organization GO:0007051 2 0.023
negative regulation of signaling GO:0023057 157 0.022
regulation of purine nucleotide catabolic process GO:0033121 65 0.022
response to growth factor GO:0070848 189 0.022
cellular response to stress GO:0033554 269 0.022
negative regulation of metabolic process GO:0009892 331 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
protein complex subunit organization GO:0071822 302 0.022
single organism reproductive process GO:0044702 297 0.021
centrosome cycle GO:0007098 1 0.021
regulation of molecular function GO:0065009 398 0.021
development of primary sexual characteristics GO:0045137 107 0.021
cellular amine metabolic process GO:0044106 38 0.021
regulation of ras protein signal transduction GO:0046578 45 0.020
male gamete generation GO:0048232 99 0.020
negative regulation of ion transport GO:0043271 51 0.020
rna biosynthetic process GO:0032774 380 0.020
regulation of dna metabolic process GO:0051052 60 0.020
positive regulation of cellular protein metabolic process GO:0032270 167 0.020
activation of phospholipase d activity GO:0031584 2 0.020
regulation of cell development GO:0060284 263 0.020
cellular component movement GO:0006928 248 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
localization of cell GO:0051674 202 0.019
regulation of small gtpase mediated signal transduction GO:0051056 48 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
striated muscle contraction GO:0006941 44 0.019
cellular macromolecular complex assembly GO:0034622 58 0.018
behavior GO:0007610 205 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
mrna metabolic process GO:0016071 20 0.018
growth GO:0040007 165 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
endocytosis GO:0006897 84 0.018
positive regulation of cell communication GO:0010647 271 0.017
regulation of cell proliferation GO:0042127 359 0.017
regulation of programmed cell death GO:0043067 341 0.017
transmembrane transport GO:0055085 412 0.017
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.017
maintenance of location GO:0051235 17 0.017
regulation of nucleotide catabolic process GO:0030811 65 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
amine metabolic process GO:0009308 38 0.017
positive regulation of catalytic activity GO:0043085 184 0.016
defense response GO:0006952 194 0.016
anterior posterior pattern specification GO:0009952 1 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
cytoplasmic transport GO:0016482 115 0.016
positive regulation of protein modification process GO:0031401 142 0.016
membrane organization GO:0061024 94 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.016
atp metabolic process GO:0046034 72 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
musculoskeletal movement GO:0050881 17 0.016
regulation of ras gtpase activity GO:0032318 32 0.016
actin filament based process GO:0030029 86 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
positive regulation of kinase activity GO:0033674 77 0.015
response to peptide GO:1901652 292 0.015
regulation of neuron differentiation GO:0045664 208 0.015
spermatogenesis GO:0007283 99 0.015
cell motility GO:0048870 202 0.014
regulation of transcription dna templated GO:0006355 374 0.014
cell cycle process GO:0022402 57 0.014
regulation of cellular component size GO:0032535 51 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
dendrite morphogenesis GO:0048813 43 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
protein geranylgeranylation GO:0018344 4 0.014
regulation of ion transport GO:0043269 245 0.014
positive regulation of hydrolase activity GO:0051345 86 0.014
neuron projection morphogenesis GO:0048812 122 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
anatomical structure formation involved in morphogenesis GO:0048646 83 0.013
regulation of rna metabolic process GO:0051252 391 0.013
response to reactive oxygen species GO:0000302 120 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
endomembrane system organization GO:0010256 48 0.013
positive regulation of dna metabolic process GO:0051054 39 0.013
response to biotic stimulus GO:0009607 226 0.013
positive regulation of signaling GO:0023056 270 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
learning or memory GO:0007611 90 0.013
regulation of mapk cascade GO:0043408 116 0.013
negative regulation of neuron apoptotic process GO:0043524 45 0.013
regulation of gtp catabolic process GO:0033124 58 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
negative regulation of transport GO:0051051 136 0.012
regulation of gtpase activity GO:0043087 57 0.012
gliogenesis GO:0042063 93 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
brain development GO:0007420 247 0.012
positive regulation of nervous system development GO:0051962 178 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
response to other organism GO:0051707 220 0.012
positive regulation of transferase activity GO:0051347 81 0.012
protein modification by small protein conjugation or removal GO:0070647 35 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
locomotion GO:0040011 237 0.012
purine nucleoside monophosphate metabolic process GO:0009126 84 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
positive regulation of gtp catabolic process GO:0033126 48 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
organelle assembly GO:0070925 22 0.011
reproductive structure development GO:0048608 128 0.011
response to electrical stimulus GO:0051602 56 0.011
single organism behavior GO:0044708 130 0.011
organelle fission GO:0048285 25 0.011
cytoskeleton organization GO:0007010 111 0.011
regulation of neurogenesis GO:0050767 247 0.011
rna localization GO:0006403 4 0.011
neuron projection development GO:0031175 273 0.011
aging GO:0007568 241 0.011
organic acid metabolic process GO:0006082 292 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
divalent inorganic cation transport GO:0072511 134 0.011
cell part morphogenesis GO:0032990 123 0.011
proteolysis GO:0006508 175 0.011
cation transmembrane transport GO:0098655 263 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
positive regulation of gtpase activity GO:0043547 47 0.011
regulation of transferase activity GO:0051338 123 0.010
phototransduction visible light GO:0007603 2 0.010
ribonucleoside monophosphate metabolic process GO:0009161 88 0.010
regulation of establishment of protein localization GO:0070201 69 0.010
negative regulation of cellular metabolic process GO:0031324 281 0.010
regulation of cell differentiation GO:0045595 320 0.010
positive regulation of signal transduction GO:0009967 175 0.010
regulation of cellular amine metabolic process GO:0033238 8 0.010
intracellular transport GO:0046907 185 0.010
double strand break repair GO:0006302 1 0.010
response to light intensity GO:0009642 9 0.010

Eif5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
muscle tissue disease DOID:66 0 0.033
musculoskeletal system disease DOID:17 0 0.033
disease of anatomical entity DOID:7 0 0.033
myopathy DOID:423 0 0.033
muscular dystrophy DOID:9884 0 0.033
muscular disease DOID:0080000 0 0.033