Rattus norvegicus

18 known processes

Eif5

eukaryotic translation initiation factor 5

Eif5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular catabolic process GO:0044248 295 0.412
regulation of cellular component organization GO:0051128 368 0.333
aromatic compound catabolic process GO:0019439 168 0.305
purine ribonucleoside catabolic process GO:0046130 124 0.287
ribonucleoside catabolic process GO:0042454 126 0.264
purine nucleotide catabolic process GO:0006195 136 0.210
anatomical structure morphogenesis GO:0009653 298 0.196
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.188
carbohydrate derivative catabolic process GO:1901136 147 0.178
nucleoside triphosphate catabolic process GO:0009143 123 0.174
catabolic process GO:0009056 351 0.174
regulation of cellular protein metabolic process GO:0032268 267 0.171
organophosphate catabolic process GO:0046434 148 0.169
response to cytokine GO:0034097 215 0.162
nucleoside phosphate catabolic process GO:1901292 140 0.148
organelle organization GO:0006996 266 0.142
vesicle mediated transport GO:0016192 181 0.139
cellular component morphogenesis GO:0032989 155 0.133
purine containing compound catabolic process GO:0072523 138 0.132
purine ribonucleotide catabolic process GO:0009154 136 0.131
ribonucleotide catabolic process GO:0009261 136 0.129
purine nucleoside triphosphate catabolic process GO:0009146 122 0.125
macromolecule localization GO:0033036 252 0.123
nucleobase containing compound catabolic process GO:0034655 152 0.121
ribonucleoside triphosphate metabolic process GO:0009199 141 0.118
organic substance catabolic process GO:1901575 316 0.113
reproduction GO:0000003 245 0.113
purine nucleoside metabolic process GO:0042278 169 0.111
organonitrogen compound catabolic process GO:1901565 179 0.111
macromolecular complex subunit organization GO:0043933 339 0.110
ribonucleotide metabolic process GO:0009259 231 0.107
nucleoside metabolic process GO:0009116 179 0.104
cellular nitrogen compound catabolic process GO:0044270 163 0.102
nucleoside catabolic process GO:0009164 126 0.102
regulation of catalytic activity GO:0050790 304 0.102
glycosyl compound catabolic process GO:1901658 126 0.097
nucleotide catabolic process GO:0009166 139 0.095
purine nucleoside catabolic process GO:0006152 124 0.095
ribonucleoside triphosphate catabolic process GO:0009203 122 0.094
establishment of protein localization GO:0045184 141 0.093
ribonucleoside metabolic process GO:0009119 174 0.088
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.086
heterocycle catabolic process GO:0046700 167 0.085
small gtpase mediated signal transduction GO:0007264 36 0.084
regulation of protein metabolic process GO:0051246 289 0.080
nucleoside triphosphate metabolic process GO:0009141 144 0.079
purine ribonucleoside metabolic process GO:0046128 168 0.079
protein transport GO:0015031 132 0.079
organophosphate metabolic process GO:0019637 370 0.076
protein localization GO:0008104 191 0.069
multicellular organismal reproductive process GO:0048609 233 0.068
nucleotide metabolic process GO:0009117 279 0.068
nucleoside phosphate metabolic process GO:0006753 283 0.067
regulation of signal transduction GO:0009966 318 0.066
purine ribonucleotide metabolic process GO:0009150 227 0.066
cellular component assembly GO:0022607 360 0.065
nucleoside monophosphate catabolic process GO:0009125 56 0.065
protein complex assembly GO:0006461 263 0.064
sexual reproduction GO:0019953 148 0.060
dna metabolic process GO:0006259 96 0.060
glycosyl compound metabolic process GO:1901657 182 0.058
atp catabolic process GO:0006200 54 0.058
guanosine containing compound catabolic process GO:1901069 71 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.055
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.054
dendrite development GO:0016358 72 0.053
purine nucleoside triphosphate metabolic process GO:0009144 141 0.052
ribose phosphate metabolic process GO:0019693 235 0.051
positive regulation of cellular component organization GO:0051130 200 0.051
purine nucleotide metabolic process GO:0006163 229 0.049
regulation of cellular response to stress GO:0080135 49 0.049
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.049
single organism catabolic process GO:0044712 283 0.049
regulation of hydrolase activity GO:0051336 143 0.047
ras protein signal transduction GO:0007265 29 0.047
positive regulation of cellular biosynthetic process GO:0031328 295 0.046
purine containing compound metabolic process GO:0072521 253 0.046
protein phosphorylation GO:0006468 345 0.045
programmed cell death GO:0012501 392 0.045
metal ion transport GO:0030001 289 0.044
guanosine containing compound metabolic process GO:1901068 74 0.044
gtp catabolic process GO:0006184 71 0.044
carbohydrate derivative metabolic process GO:1901135 346 0.043
organic cyclic compound catabolic process GO:1901361 175 0.043
cellular protein localization GO:0034613 122 0.042
nucleic acid templated transcription GO:0097659 379 0.042
cell projection organization GO:0030030 302 0.041
regulation of cellular localization GO:0060341 263 0.041
gtp metabolic process GO:0046039 72 0.040
regulation of catabolic process GO:0009894 113 0.040
regulation of cellular catabolic process GO:0031329 101 0.039
regulation of apoptotic process GO:0042981 335 0.039
response to nutrient levels GO:0031667 370 0.038
regulation of nucleotide metabolic process GO:0006140 117 0.038
positive regulation of protein metabolic process GO:0051247 178 0.037
neuron differentiation GO:0030182 368 0.037
cellular response to cytokine stimulus GO:0071345 127 0.037
regulation of phosphate metabolic process GO:0019220 349 0.037
regulation of phosphorus metabolic process GO:0051174 349 0.037
intracellular protein transport GO:0006886 79 0.036
positive regulation of biosynthetic process GO:0009891 319 0.036
acrosome assembly GO:0001675 3 0.035
rna metabolic process GO:0016070 406 0.035
regulation of cell projection organization GO:0031344 175 0.035
cellular component biogenesis GO:0044085 368 0.034
single organism intracellular transport GO:1902582 166 0.033
positive regulation of cell projection organization GO:0031346 111 0.033
negative regulation of cell communication GO:0010648 158 0.033
regulation of protein kinase activity GO:0045859 105 0.033
protein targeting GO:0006605 61 0.033
cell projection assembly GO:0030031 21 0.032
multi organism reproductive process GO:0044703 262 0.032
single organism cellular localization GO:1902580 102 0.032
neuron development GO:0048666 286 0.032
positive regulation of catabolic process GO:0009896 78 0.031
reproductive process GO:0022414 372 0.031
apoptotic process GO:0006915 381 0.031
regulation of organelle organization GO:0033043 80 0.031
negative regulation of programmed cell death GO:0043069 183 0.030
positive regulation of transcription dna templated GO:0045893 197 0.030
cellular response to endogenous stimulus GO:0071495 377 0.030
establishment of protein localization to organelle GO:0072594 44 0.030
positive regulation of developmental process GO:0051094 283 0.030
single organism organelle organization GO:1902589 180 0.029
response to extracellular stimulus GO:0009991 380 0.029
cellular macromolecule localization GO:0070727 122 0.029
cell morphogenesis involved in differentiation GO:0000904 119 0.029
multicellular organism reproduction GO:0032504 233 0.029
regulation of neuron projection development GO:0010975 161 0.028
response to external biotic stimulus GO:0043207 221 0.028
regulation of response to stress GO:0080134 126 0.028
lipid metabolic process GO:0006629 283 0.028
cation transport GO:0006812 382 0.027
response to toxic substance GO:0009636 133 0.027
regulation of cell morphogenesis GO:0022604 77 0.027
nuclear transport GO:0051169 49 0.026
macromolecular complex assembly GO:0065003 273 0.026
protein complex biogenesis GO:0070271 263 0.026
regulation of protein localization GO:0032880 81 0.026
positive regulation of protein import into nucleus translocation GO:0033160 7 0.026
regulation of protein modification process GO:0031399 194 0.026
positive regulation of gene expression GO:0010628 244 0.025
mapk cascade GO:0000165 140 0.025
gamete generation GO:0007276 124 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
neurological system process GO:0050877 219 0.023
regulation of purine nucleotide metabolic process GO:1900542 115 0.023
positive regulation of molecular function GO:0044093 230 0.023
cytokine mediated signaling pathway GO:0019221 43 0.023
regulation of phosphorylation GO:0042325 248 0.023
spindle organization GO:0007051 2 0.023
negative regulation of signaling GO:0023057 157 0.022
regulation of purine nucleotide catabolic process GO:0033121 65 0.022
response to growth factor GO:0070848 189 0.022
cellular response to stress GO:0033554 269 0.022
negative regulation of metabolic process GO:0009892 331 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
protein complex subunit organization GO:0071822 302 0.022
single organism reproductive process GO:0044702 297 0.021
centrosome cycle GO:0007098 1 0.021
regulation of molecular function GO:0065009 398 0.021
development of primary sexual characteristics GO:0045137 107 0.021
cellular amine metabolic process GO:0044106 38 0.021
regulation of ras protein signal transduction GO:0046578 45 0.020
male gamete generation GO:0048232 99 0.020
negative regulation of ion transport GO:0043271 51 0.020
rna biosynthetic process GO:0032774 380 0.020
regulation of dna metabolic process GO:0051052 60 0.020
positive regulation of cellular protein metabolic process GO:0032270 167 0.020
activation of phospholipase d activity GO:0031584 2 0.020
regulation of cell development GO:0060284 263 0.020
cellular component movement GO:0006928 248 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
localization of cell GO:0051674 202 0.019
regulation of small gtpase mediated signal transduction GO:0051056 48 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
striated muscle contraction GO:0006941 44 0.019
cellular macromolecular complex assembly GO:0034622 58 0.018
behavior GO:0007610 205 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
mrna metabolic process GO:0016071 20 0.018
growth GO:0040007 165 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
endocytosis GO:0006897 84 0.018
positive regulation of cell communication GO:0010647 271 0.017
regulation of cell proliferation GO:0042127 359 0.017
regulation of programmed cell death GO:0043067 341 0.017
transmembrane transport GO:0055085 412 0.017
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.017
maintenance of location GO:0051235 17 0.017
regulation of nucleotide catabolic process GO:0030811 65 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
amine metabolic process GO:0009308 38 0.017
positive regulation of catalytic activity GO:0043085 184 0.016
defense response GO:0006952 194 0.016
anterior posterior pattern specification GO:0009952 1 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
cytoplasmic transport GO:0016482 115 0.016
positive regulation of protein modification process GO:0031401 142 0.016
membrane organization GO:0061024 94 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.016
atp metabolic process GO:0046034 72 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
musculoskeletal movement GO:0050881 17 0.016
regulation of ras gtpase activity GO:0032318 32 0.016
actin filament based process GO:0030029 86 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
positive regulation of kinase activity GO:0033674 77 0.015
response to peptide GO:1901652 292 0.015
regulation of neuron differentiation GO:0045664 208 0.015
spermatogenesis GO:0007283 99 0.015
cell motility GO:0048870 202 0.014
regulation of transcription dna templated GO:0006355 374 0.014
cell cycle process GO:0022402 57 0.014
regulation of cellular component size GO:0032535 51 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
dendrite morphogenesis GO:0048813 43 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
protein geranylgeranylation GO:0018344 4 0.014
regulation of ion transport GO:0043269 245 0.014
positive regulation of hydrolase activity GO:0051345 86 0.014
neuron projection morphogenesis GO:0048812 122 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
anatomical structure formation involved in morphogenesis GO:0048646 83 0.013
regulation of rna metabolic process GO:0051252 391 0.013
response to reactive oxygen species GO:0000302 120 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
endomembrane system organization GO:0010256 48 0.013
positive regulation of dna metabolic process GO:0051054 39 0.013
response to biotic stimulus GO:0009607 226 0.013
positive regulation of signaling GO:0023056 270 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
learning or memory GO:0007611 90 0.013
regulation of mapk cascade GO:0043408 116 0.013
negative regulation of neuron apoptotic process GO:0043524 45 0.013
regulation of gtp catabolic process GO:0033124 58 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
negative regulation of transport GO:0051051 136 0.012
regulation of gtpase activity GO:0043087 57 0.012
gliogenesis GO:0042063 93 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
brain development GO:0007420 247 0.012
positive regulation of nervous system development GO:0051962 178 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
response to other organism GO:0051707 220 0.012
positive regulation of transferase activity GO:0051347 81 0.012
protein modification by small protein conjugation or removal GO:0070647 35 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
locomotion GO:0040011 237 0.012
purine nucleoside monophosphate metabolic process GO:0009126 84 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
positive regulation of gtp catabolic process GO:0033126 48 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
organelle assembly GO:0070925 22 0.011
reproductive structure development GO:0048608 128 0.011
response to electrical stimulus GO:0051602 56 0.011
single organism behavior GO:0044708 130 0.011
organelle fission GO:0048285 25 0.011
cytoskeleton organization GO:0007010 111 0.011
regulation of neurogenesis GO:0050767 247 0.011
rna localization GO:0006403 4 0.011
neuron projection development GO:0031175 273 0.011
aging GO:0007568 241 0.011
organic acid metabolic process GO:0006082 292 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
divalent inorganic cation transport GO:0072511 134 0.011
cell part morphogenesis GO:0032990 123 0.011
proteolysis GO:0006508 175 0.011
cation transmembrane transport GO:0098655 263 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
positive regulation of gtpase activity GO:0043547 47 0.011
regulation of transferase activity GO:0051338 123 0.010
phototransduction visible light GO:0007603 2 0.010
ribonucleoside monophosphate metabolic process GO:0009161 88 0.010
regulation of establishment of protein localization GO:0070201 69 0.010
negative regulation of cellular metabolic process GO:0031324 281 0.010
regulation of cell differentiation GO:0045595 320 0.010
positive regulation of signal transduction GO:0009967 175 0.010
regulation of cellular amine metabolic process GO:0033238 8 0.010
intracellular transport GO:0046907 185 0.010
double strand break repair GO:0006302 1 0.010
response to light intensity GO:0009642 9 0.010

Eif5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.033
muscular disease DOID:0080000 0 0.033
muscular dystrophy DOID:9884 0 0.033
disease of anatomical entity DOID:7 0 0.033
musculoskeletal system disease DOID:17 0 0.033
muscle tissue disease DOID:66 0 0.033