Rattus norvegicus

30 known processes

Epha3

Eph receptor A3

Epha3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 365 0.366
inorganic ion transmembrane transport GO:0098660 229 0.268
cellular lipid metabolic process GO:0044255 208 0.231
protein complex assembly GO:0006461 263 0.164
anion transport GO:0006820 178 0.157
carboxylic acid metabolic process GO:0019752 289 0.149
organic acid metabolic process GO:0006082 292 0.147
synaptic growth at neuromuscular junction GO:0051124 1 0.129
cellular response to organonitrogen compound GO:0071417 197 0.122
inorganic cation transmembrane transport GO:0098662 202 0.114
brain development GO:0007420 247 0.113
Fly
macromolecular complex assembly GO:0065003 273 0.109
single organism biosynthetic process GO:0044711 342 0.108
regulation of molecular function GO:0065009 398 0.099
Human Rat
cellular response to nitrogen compound GO:1901699 210 0.094
protein complex biogenesis GO:0070271 263 0.094
response to purine containing compound GO:0014074 126 0.092
oxoacid metabolic process GO:0043436 290 0.092
lipid metabolic process GO:0006629 283 0.088
synaptic transmission GO:0007268 235 0.087
organic anion transport GO:0015711 132 0.086
cation homeostasis GO:0055080 195 0.084
organic hydroxy compound metabolic process GO:1901615 115 0.080
Fly
response to hydrogen peroxide GO:0042542 89 0.080
regulation of cellular component organization GO:0051128 368 0.079
Human Mouse
macromolecular complex subunit organization GO:0043933 339 0.078
response to camp GO:0051591 91 0.077
response to extracellular stimulus GO:0009991 380 0.076
protein phosphorylation GO:0006468 345 0.073
Human Mouse Rat Worm
cellular response to organic cyclic compound GO:0071407 202 0.072
neuron development GO:0048666 286 0.072
Human Mouse Rat Worm
cellular component assembly GO:0022607 360 0.069
Human
positive regulation of amine transport GO:0051954 26 0.068
immune response GO:0006955 104 0.067
Fly
protein complex subunit organization GO:0071822 302 0.065
response to peptide hormone GO:0043434 278 0.063
response to inorganic substance GO:0010035 377 0.062
positive regulation of protein metabolic process GO:0051247 178 0.060
cellular ketone metabolic process GO:0042180 51 0.059
transmembrane transport GO:0055085 412 0.059
cellular amine metabolic process GO:0044106 38 0.059
intracellular signal transduction GO:0035556 314 0.059
Rat
response to organophosphorus GO:0046683 102 0.058
negative regulation of metabolic process GO:0009892 331 0.057
cation transmembrane transport GO:0098655 263 0.056
reproductive structure development GO:0048608 128 0.056
cellular response to endogenous stimulus GO:0071495 377 0.055
rhythmic process GO:0048511 156 0.055
response to mineralocorticoid GO:0051385 49 0.055
response to estrogen GO:0043627 232 0.055
central nervous system development GO:0007417 311 0.055
Fly
ovulation cycle GO:0042698 67 0.054
positive regulation of cellular protein metabolic process GO:0032270 167 0.054
cell motility GO:0048870 202 0.054
Mouse
reproductive system development GO:0061458 128 0.053
reproductive process GO:0022414 372 0.053
Worm
head development GO:0060322 247 0.052
Fly
regulation of cellular ketone metabolic process GO:0010565 27 0.052
response to estradiol GO:0032355 164 0.051
organic acid transport GO:0015849 116 0.050
cellular amino acid metabolic process GO:0006520 107 0.050
response to corticosterone GO:0051412 40 0.049
response to alkaloid GO:0043279 132 0.048
regulation of nervous system development GO:0051960 264 0.048
Human
response to growth factor GO:0070848 189 0.048
carboxylic acid transport GO:0046942 115 0.048
positive regulation of phosphorus metabolic process GO:0010562 262 0.047
ion homeostasis GO:0050801 212 0.047
regulation of multicellular organismal development GO:2000026 376 0.047
Human Mouse
purine nucleotide metabolic process GO:0006163 229 0.046
Human
signal release GO:0023061 145 0.046
protein oligomerization GO:0051259 191 0.046
purine containing compound metabolic process GO:0072521 253 0.046
Human
multicellular organism reproduction GO:0032504 233 0.045
Worm
organophosphate biosynthetic process GO:0090407 143 0.045
gonad development GO:0008406 104 0.045
amine metabolic process GO:0009308 38 0.044
g protein coupled receptor signaling pathway GO:0007186 242 0.043
response to luteinizing hormone GO:0034699 5 0.042
regulation of membrane potential GO:0042391 110 0.042
regulation of neuron differentiation GO:0045664 208 0.042
Human
cellular response to oxygen containing compound GO:1901701 386 0.041
Human
regulation of cellular protein metabolic process GO:0032268 267 0.040
regulation of cellular localization GO:0060341 263 0.040
neuron differentiation GO:0030182 368 0.040
Human Mouse Rat Worm
reproduction GO:0000003 245 0.040
Worm
regulation of protein metabolic process GO:0051246 289 0.039
regulation of cellular amino acid metabolic process GO:0006521 2 0.039
regulation of phosphate metabolic process GO:0019220 349 0.039
Human
cation transport GO:0006812 382 0.039
positive regulation of cellular component organization GO:0051130 200 0.039
Human
response to nutrient levels GO:0031667 370 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.037
organophosphate metabolic process GO:0019637 370 0.037
Human
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.037
regulation of protein phosphorylation GO:0001932 183 0.037
negative regulation of phosphorus metabolic process GO:0010563 80 0.037
neuron projection development GO:0031175 273 0.036
Human Mouse Rat Worm
positive regulation of signal transduction GO:0009967 175 0.036
Rat
salivary gland morphogenesis GO:0007435 1 0.036
response to bacterium GO:0009617 200 0.036
cellular catabolic process GO:0044248 295 0.035
Human
growth GO:0040007 165 0.035
multicellular organismal reproductive process GO:0048609 233 0.035
Worm
positive regulation of catalytic activity GO:0043085 184 0.035
regulation of cellular amine metabolic process GO:0033238 8 0.034
purine ribonucleotide metabolic process GO:0009150 227 0.034
Human
regulation of neuron projection development GO:0010975 161 0.033
Human
response to oxidative stress GO:0006979 186 0.033
phospholipid metabolic process GO:0006644 61 0.033
developmental process involved in reproduction GO:0003006 159 0.032
Worm
catabolic process GO:0009056 351 0.032
Human
cell cell signaling GO:0007267 335 0.031
positive regulation of neurogenesis GO:0050769 165 0.031
Human
metal ion transport GO:0030001 289 0.031
regulation of transferase activity GO:0051338 123 0.031
regulation of kinase activity GO:0043549 117 0.030
protein homooligomerization GO:0051260 91 0.030
positive regulation of kinase activity GO:0033674 77 0.030
cellular component biogenesis GO:0044085 368 0.029
Human
secretion GO:0046903 307 0.029
response to ammonium ion GO:0060359 71 0.029
organonitrogen compound biosynthetic process GO:1901566 167 0.029
response to insulin GO:0032868 133 0.028
regulation of protein modification process GO:0031399 194 0.028
cellular response to histamine GO:0071420 3 0.028
glutamate receptor signaling pathway GO:0007215 43 0.028
small molecule biosynthetic process GO:0044283 124 0.028
regulation of ion transport GO:0043269 245 0.027
glycerolipid metabolic process GO:0046486 67 0.027
positive regulation of cellular component biogenesis GO:0044089 55 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
cellular response to stress GO:0033554 269 0.027
positive regulation of nervous system development GO:0051962 178 0.027
Human
sex differentiation GO:0007548 113 0.027
male sex differentiation GO:0046661 64 0.027
single organism organelle organization GO:1902589 180 0.027
Human
positive regulation of developmental process GO:0051094 283 0.026
Human
response to ketone GO:1901654 182 0.026
development of primary sexual characteristics GO:0045137 107 0.026
nucleotide metabolic process GO:0009117 279 0.026
Human
response to amino acid GO:0043200 75 0.025
regulation of nucleic acid templated transcription GO:1903506 380 0.025
Rat
negative regulation of innate immune response GO:0045824 4 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.025
Human
synaptic transmission glycinergic GO:0060012 2 0.024
regulation of intracellular signal transduction GO:1902531 218 0.024
Human Rat
positive regulation of protein phosphorylation GO:0001934 135 0.024
regulation of protein kinase activity GO:0045859 105 0.024
alcohol biosynthetic process GO:0046165 38 0.024
single organism reproductive process GO:0044702 297 0.024
Worm
salivary gland development GO:0007431 3 0.023
insecticide metabolic process GO:0017143 4 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
regulation of system process GO:0044057 208 0.023
cellular protein localization GO:0034613 122 0.023
heart development GO:0007507 72 0.022
Mouse
activation of protein kinase activity GO:0032147 47 0.022
positive regulation of protein modification process GO:0031401 142 0.022
response to peptide GO:1901652 292 0.022
oxidation reduction process GO:0055114 304 0.022
response to vitamin GO:0033273 131 0.022
regulation of cell proliferation GO:0042127 359 0.022
positive regulation of gene expression GO:0010628 244 0.022
regulation of catalytic activity GO:0050790 304 0.022
Human
cell projection organization GO:0030030 302 0.022
Human Mouse Rat Worm
lipid transport GO:0006869 61 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
Human
alpha amino acid catabolic process GO:1901606 20 0.021
negative regulation of cell death GO:0060548 229 0.021
neuron neuron synaptic transmission GO:0007270 60 0.021
transmission of nerve impulse GO:0019226 42 0.021
second messenger mediated signaling GO:0019932 51 0.021
Rat
regulation of cell differentiation GO:0045595 320 0.021
Human Mouse
positive regulation of molecular function GO:0044093 230 0.021
Rat
synapse organization GO:0050808 46 0.021
regulation of cell development GO:0060284 263 0.021
Human Mouse
cellular component movement GO:0006928 248 0.021
Mouse Worm
regulation of neurogenesis GO:0050767 247 0.020
Human
vesicle mediated transport GO:0016192 181 0.020
response to radiation GO:0009314 137 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
Human
cellular response to ammonium ion GO:0071242 17 0.020
alcohol metabolic process GO:0006066 77 0.019
androgen biosynthetic process GO:0006702 10 0.019
response to gamma radiation GO:0010332 24 0.019
anion transmembrane transport GO:0098656 77 0.019
astrocyte development GO:0014002 4 0.019
regulation of phosphorylation GO:0042325 248 0.019
peptidyl amino acid modification GO:0018193 126 0.019
Human Mouse Rat Worm
regulation of neurotransmitter levels GO:0001505 42 0.019
response to metal ion GO:0010038 253 0.019
regulation of rna biosynthetic process GO:2001141 381 0.018
Rat
cardiovascular system development GO:0072358 134 0.018
Mouse
organonitrogen compound catabolic process GO:1901565 179 0.018
Human
carbohydrate derivative metabolic process GO:1901135 346 0.018
Human
macromolecule localization GO:0033036 252 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
Rat
ribonucleotide biosynthetic process GO:0009260 85 0.018
myeloid cell differentiation GO:0030099 22 0.018
response to glucocorticoid GO:0051384 223 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
Human
negative regulation of vascular permeability GO:0043116 3 0.017
response to food GO:0032094 27 0.017
positive regulation of synapse assembly GO:0051965 12 0.017
homeostatic process GO:0042592 331 0.017
regulation of signal transduction GO:0009966 318 0.017
Human Rat
transcription dna templated GO:0006351 377 0.017
Rat
chemosensory behavior GO:0007635 2 0.017
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 2 0.017
rna metabolic process GO:0016070 406 0.017
Rat
cellular response to hormone stimulus GO:0032870 247 0.016
response to starvation GO:0042594 59 0.016
multi multicellular organism process GO:0044706 138 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
positive regulation of signaling GO:0023056 270 0.016
Rat
response to ethanol GO:0045471 162 0.016
regulation of catecholamine secretion GO:0050433 32 0.016
cell growth GO:0016049 104 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
Human
protein localization GO:0008104 191 0.016
response to other organism GO:0051707 220 0.016
cellular response to luteinizing hormone stimulus GO:0071373 5 0.016
cellular lipid catabolic process GO:0044242 37 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
negative regulation of cell proliferation GO:0008285 119 0.015
single organism catabolic process GO:0044712 283 0.015
Human
defense response to gram negative bacterium GO:0050829 3 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
Human
neurotransmitter transport GO:0006836 42 0.015
positive regulation of cell development GO:0010720 176 0.015
Human
catecholamine transport GO:0051937 37 0.015
blood circulation GO:0008015 183 0.015
cellular ion homeostasis GO:0006873 184 0.015
negative regulation of molecular function GO:0044092 133 0.015
negative regulation of cell differentiation GO:0045596 99 0.015
alpha amino acid metabolic process GO:1901605 71 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
sympathetic nervous system development GO:0048485 1 0.015
regulation of ion transmembrane transporter activity GO:0032412 48 0.015
regulation of hormone levels GO:0010817 187 0.015
multi organism reproductive process GO:0044703 262 0.015
Worm
regulation of erk1 and erk2 cascade GO:0070372 41 0.014
organic hydroxy compound transport GO:0015850 77 0.014
potassium ion transport GO:0006813 97 0.014
circadian rhythm GO:0007623 88 0.014
positive regulation of cell communication GO:0010647 271 0.014
Rat
cellular response to growth factor stimulus GO:0071363 162 0.014
response to hypoxia GO:0001666 231 0.014
acetyl coa metabolic process GO:0006084 17 0.014
amide biosynthetic process GO:0043604 10 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
response to oxygen levels GO:0070482 265 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
choline transport GO:0015871 4 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
Rat
response to acid chemical GO:0001101 222 0.014
Human
sexual reproduction GO:0019953 148 0.014
Worm
nucleobase containing small molecule metabolic process GO:0055086 316 0.014
Human
cellular response to fluid shear stress GO:0071498 4 0.014
positive regulation of biosynthetic process GO:0009891 319 0.013
response to amine GO:0014075 46 0.013
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
positive regulation of transferase activity GO:0051347 81 0.013
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.013
isoprenoid metabolic process GO:0006720 45 0.013
locomotion GO:0040011 237 0.013
Mouse Worm
response to lipopolysaccharide GO:0032496 191 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
response to decreased oxygen levels GO:0036293 237 0.013
cellular homeostasis GO:0019725 252 0.013
response to calcium ion GO:0051592 59 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
erythrocyte differentiation GO:0030218 1 0.013
negative regulation of signal transduction GO:0009968 83 0.013
response to activity GO:0014823 73 0.013
organelle localization GO:0051640 55 0.013
female pregnancy GO:0007565 122 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
protein heterooligomerization GO:0051291 89 0.013
rna biosynthetic process GO:0032774 380 0.013
Rat
regulation of muscle system process GO:0090257 79 0.013
organic hydroxy compound biosynthetic process GO:1901617 51 0.013
peptidyl tyrosine modification GO:0018212 72 0.013
Human Mouse Rat Worm
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
Human Mouse Rat Worm
multicellular organism growth GO:0035264 1 0.013
organic substance catabolic process GO:1901575 316 0.013
Human
regulation of neuron death GO:1901214 115 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
Human
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
regulation of cellular component movement GO:0051270 150 0.012
dephosphorylation GO:0016311 98 0.012
gliogenesis GO:0042063 93 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
Human
positive regulation of protein kinase activity GO:0045860 73 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
regulation of growth GO:0040008 105 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
response to axon injury GO:0048678 59 0.012
response to cocaine GO:0042220 39 0.012
embryo development GO:0009790 49 0.012
Worm
reactive oxygen species metabolic process GO:0072593 37 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
neuron projection regeneration GO:0031102 35 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
Mouse Rat Worm
neuron death GO:0070997 127 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
Worm
regulation of rna metabolic process GO:0051252 391 0.011
Rat
glycerophospholipid metabolic process GO:0006650 47 0.011
response to cgmp GO:0070305 3 0.011
response to reactive oxygen species GO:0000302 120 0.011
maintenance of location GO:0051235 17 0.011
nucleic acid templated transcription GO:0097659 379 0.011
Rat
proteolysis GO:0006508 175 0.011
heart morphogenesis GO:0003007 3 0.011
positive regulation of immunoglobulin production GO:0002639 4 0.011
mapk cascade GO:0000165 140 0.011
response to toxic substance GO:0009636 133 0.011
inflammatory response GO:0006954 150 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
gastrulation GO:0007369 2 0.011
peptidyl serine phosphorylation GO:0018105 33 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
response to histamine GO:0034776 3 0.011
regulation of immune system process GO:0002682 123 0.011
organophosphate catabolic process GO:0046434 148 0.011
Human
regulation of cell projection organization GO:0031344 175 0.011
Human
adult locomotory behavior GO:0008344 4 0.011
negative regulation of protein modification process GO:0031400 52 0.011
negative regulation of transport GO:0051051 136 0.011
response to nicotine GO:0035094 51 0.011
gtp metabolic process GO:0046039 72 0.011
Human
erk1 and erk2 cascade GO:0070371 48 0.011
response to temperature stimulus GO:0009266 94 0.010
monocarboxylic acid transport GO:0015718 52 0.010
killing of cells of other organism GO:0031640 1 0.010
negative regulation of cell development GO:0010721 82 0.010
regulation of neuron apoptotic process GO:0043523 83 0.010
multicellular organismal signaling GO:0035637 44 0.010
peptidyl serine modification GO:0018209 34 0.010
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.010
regulation of protein serine threonine kinase activity GO:0071900 64 0.010
response to carbohydrate GO:0009743 183 0.010
response to external biotic stimulus GO:0043207 221 0.010
cellular amide metabolic process GO:0043603 44 0.010
developmental growth GO:0048589 100 0.010

Epha3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
central nervous system disease DOID:331 0 0.017
musculoskeletal system disease DOID:17 0 0.016
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011