Rattus norvegicus

7 known processes

Itpkc

inositol 1,4,5-trisphosphate 3-kinase C

Itpkc biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transcription dna templated GO:0006351 377 0.100
intracellular signal transduction GO:0035556 314 0.095
cellular ketone metabolic process GO:0042180 51 0.092
neuron differentiation GO:0030182 368 0.089
Rat
response to inorganic substance GO:0010035 377 0.085
regulation of molecular function GO:0065009 398 0.069
positive regulation of signaling GO:0023056 270 0.068
organic acid metabolic process GO:0006082 292 0.063
regulation of phosphate metabolic process GO:0019220 349 0.063
nucleic acid templated transcription GO:0097659 379 0.062
cell projection organization GO:0030030 302 0.061
Rat
lipid metabolic process GO:0006629 283 0.059
positive regulation of neurogenesis GO:0050769 165 0.059
Rat
macromolecule localization GO:0033036 252 0.056
transcription from rna polymerase ii promoter GO:0006366 252 0.055
regulation of nervous system development GO:0051960 264 0.055
Rat
neuron development GO:0048666 286 0.054
Rat
response to peptide GO:1901652 292 0.052
regulation of cell development GO:0060284 263 0.052
Rat
carboxylic acid metabolic process GO:0019752 289 0.052
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.051
regulation of rna metabolic process GO:0051252 391 0.050
oxoacid metabolic process GO:0043436 290 0.049
response to temperature stimulus GO:0009266 94 0.047
regulation of cellular protein metabolic process GO:0032268 267 0.047
cellular response to oxygen containing compound GO:1901701 386 0.046
single organism behavior GO:0044708 130 0.046
regulation of protein metabolic process GO:0051246 289 0.045
regulation of signal transduction GO:0009966 318 0.045
positive regulation of nervous system development GO:0051962 178 0.044
Rat
regulation of transcription dna templated GO:0006355 374 0.044
apoptotic process GO:0006915 381 0.044
programmed cell death GO:0012501 392 0.043
regulation of phosphorus metabolic process GO:0051174 349 0.042
cellular component movement GO:0006928 248 0.042
regulation of nucleic acid templated transcription GO:1903506 380 0.041
cellular response to hormone stimulus GO:0032870 247 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.040
response to nutrient levels GO:0031667 370 0.040
regulation of apoptotic process GO:0042981 335 0.040
regulation of cell differentiation GO:0045595 320 0.040
Rat
regulation of rna biosynthetic process GO:2001141 381 0.040
negative regulation of metabolic process GO:0009892 331 0.039
negative regulation of macromolecule metabolic process GO:0010605 260 0.039
negative regulation of response to stimulus GO:0048585 155 0.039
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.038
rna biosynthetic process GO:0032774 380 0.038
negative regulation of apoptotic process GO:0043066 181 0.036
protein phosphorylation GO:0006468 345 0.036
Rat
cellular response to endogenous stimulus GO:0071495 377 0.036
nucleotide metabolic process GO:0009117 279 0.035
positive regulation of multicellular organismal process GO:0051240 387 0.035
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.034
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
neuron projection development GO:0031175 273 0.032
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.032
regulation of cellular localization GO:0060341 263 0.032
multi organism reproductive process GO:0044703 262 0.032
cellular response to lipid GO:0071396 201 0.031
response to peptide hormone GO:0043434 278 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.031
response to nutrient GO:0007584 248 0.031
regulation of programmed cell death GO:0043067 341 0.031
cognition GO:0050890 92 0.031
regulation of neurogenesis GO:0050767 247 0.030
Rat
secretion by cell GO:0032940 248 0.030
positive regulation of apoptotic process GO:0043065 154 0.030
positive regulation of rna biosynthetic process GO:1902680 197 0.030
positive regulation of developmental process GO:0051094 283 0.030
Rat
regulation of intracellular signal transduction GO:1902531 218 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
positive regulation of cell death GO:0010942 184 0.029
reproductive process GO:0022414 372 0.029
organophosphate metabolic process GO:0019637 370 0.029
Fly
cellular response to stress GO:0033554 269 0.028
regulation of cell projection organization GO:0031344 175 0.028
Rat
response to extracellular stimulus GO:0009991 380 0.028
ribonucleotide metabolic process GO:0009259 231 0.028
positive regulation of neuron projection development GO:0010976 99 0.028
Rat
locomotion GO:0040011 237 0.028
regulation of neuron differentiation GO:0045664 208 0.027
Rat
positive regulation of cell development GO:0010720 176 0.027
Rat
negative regulation of cell death GO:0060548 229 0.027
rna metabolic process GO:0016070 406 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
regulation of cellular component organization GO:0051128 368 0.027
Rat
regulation of response to external stimulus GO:0032101 106 0.027
positive regulation of gene expression GO:0010628 244 0.026
negative regulation of cellular biosynthetic process GO:0031327 161 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
protein localization GO:0008104 191 0.026
negative regulation of cellular metabolic process GO:0031324 281 0.026
negative regulation of protein metabolic process GO:0051248 114 0.026
central nervous system development GO:0007417 311 0.026
positive regulation of cell differentiation GO:0045597 217 0.025
Rat
positive regulation of cell communication GO:0010647 271 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
cellular lipid metabolic process GO:0044255 208 0.025
cellular component assembly GO:0022607 360 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
regulation of neuron projection development GO:0010975 161 0.025
Rat
cellular catabolic process GO:0044248 295 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
defense response GO:0006952 194 0.024
positive regulation of protein modification process GO:0031401 142 0.023
regulation of hydrolase activity GO:0051336 143 0.023
organic anion transport GO:0015711 132 0.023
anion transport GO:0006820 178 0.022
amine metabolic process GO:0009308 38 0.022
reproduction GO:0000003 245 0.022
adult locomotory behavior GO:0008344 4 0.022
cellular amine metabolic process GO:0044106 38 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
neurological system process GO:0050877 219 0.022
cell motility GO:0048870 202 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
positive regulation of secretion GO:0051047 140 0.022
regulation of transferase activity GO:0051338 123 0.022
regulation of protein modification process GO:0031399 194 0.021
catabolic process GO:0009056 351 0.021
protein complex assembly GO:0006461 263 0.021
metal ion transport GO:0030001 289 0.021
regeneration GO:0031099 163 0.021
regulation of phosphorylation GO:0042325 248 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
response to estradiol GO:0032355 164 0.021
brain development GO:0007420 247 0.020
female pregnancy GO:0007565 122 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
Rat
positive regulation of protein metabolic process GO:0051247 178 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
response to cytokine GO:0034097 215 0.020
single organism biosynthetic process GO:0044711 342 0.020
Fly
negative regulation of signaling GO:0023057 157 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
multicellular organism reproduction GO:0032504 233 0.020
regulation of neuron death GO:1901214 115 0.020
purine containing compound metabolic process GO:0072521 253 0.020
negative regulation of developmental process GO:0051093 125 0.020
small molecule biosynthetic process GO:0044283 124 0.020
Fly
chemosensory behavior GO:0007635 2 0.020
negative regulation of cell differentiation GO:0045596 99 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
Rat
response to estrogen GO:0043627 232 0.019
regulation of cell proliferation GO:0042127 359 0.019
negative regulation of neurogenesis GO:0050768 78 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
response to ketone GO:1901654 182 0.019
regulation of catalytic activity GO:0050790 304 0.019
negative regulation of rna metabolic process GO:0051253 123 0.019
negative regulation of gene expression GO:0010629 199 0.019
proteolysis GO:0006508 175 0.019
neuron death GO:0070997 127 0.019
cellular component biogenesis GO:0044085 368 0.019
response to oxygen levels GO:0070482 265 0.019
jak stat cascade GO:0007259 26 0.019
response to metal ion GO:0010038 253 0.018
carboxylic acid transport GO:0046942 115 0.018
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
positive regulation of molecular function GO:0044093 230 0.018
calcium ion transmembrane transport GO:0070588 70 0.018
response to other organism GO:0051707 220 0.018
negative regulation of cell communication GO:0010648 158 0.018
regulation of defense response GO:0031347 68 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
Rat
negative regulation of nervous system development GO:0051961 79 0.018
response to wounding GO:0009611 254 0.018
positive regulation of signal transduction GO:0009967 175 0.018
cell cell signaling GO:0007267 335 0.018
lipid biosynthetic process GO:0008610 128 0.017
ion transmembrane transport GO:0034220 365 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
cellular response to peptide hormone stimulus GO:0071375 120 0.017
oxidation reduction process GO:0055114 304 0.017
response to radiation GO:0009314 137 0.017
protein complex subunit organization GO:0071822 302 0.017
neuromuscular process GO:0050905 2 0.017
circulatory system process GO:0003013 183 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
Rat
regulation of hormone levels GO:0010817 187 0.017
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.017
muscle cell proliferation GO:0033002 84 0.017
response to toxic substance GO:0009636 133 0.017
negative regulation of molecular function GO:0044092 133 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
ras protein signal transduction GO:0007265 29 0.016
carbohydrate metabolic process GO:0005975 130 0.016
organ regeneration GO:0031100 101 0.016
positive regulation of transport GO:0051050 245 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
cation transport GO:0006812 382 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
cellular chemical homeostasis GO:0055082 247 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
Rat
cellular response to peptide GO:1901653 133 0.016
macromolecular complex subunit organization GO:0043933 339 0.015
regulation of protein kinase activity GO:0045859 105 0.015
response to decreased oxygen levels GO:0036293 237 0.015
regulation of cellular component movement GO:0051270 150 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
cytokine production GO:0001816 61 0.015
transmembrane transport GO:0055085 412 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
dna metabolic process GO:0006259 96 0.015
organic acid transport GO:0015849 116 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
regulation of membrane potential GO:0042391 110 0.015
regulation of cell motility GO:2000145 131 0.015
head development GO:0060322 247 0.015
cellular hormone metabolic process GO:0034754 49 0.015
cell projection morphogenesis GO:0048858 123 0.015
Rat
vesicle mediated transport GO:0016192 181 0.015
response to organophosphorus GO:0046683 102 0.015
regulation of cell migration GO:0030334 128 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
positive regulation of cell proliferation GO:0008284 249 0.014
negative regulation of phosphorus metabolic process GO:0010563 80 0.014
establishment of protein localization GO:0045184 141 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
multi multicellular organism process GO:0044706 138 0.014
olfactory behavior GO:0042048 2 0.014
single organism catabolic process GO:0044712 283 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
circadian rhythm GO:0007623 88 0.014
hormone metabolic process GO:0042445 69 0.014
response to purine containing compound GO:0014074 126 0.014
macromolecular complex assembly GO:0065003 273 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.014
regulation of metal ion transport GO:0010959 118 0.014
regulation of system process GO:0044057 208 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
response to alkaloid GO:0043279 132 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
negative regulation of catalytic activity GO:0043086 103 0.013
cellular response to alcohol GO:0097306 87 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
response to glucocorticoid GO:0051384 223 0.013
immune system process GO:0002376 204 0.013
response to ammonium ion GO:0060359 71 0.013
chemical homeostasis GO:0048878 292 0.013
positive regulation of secretion by cell GO:1903532 128 0.013
isoprenoid metabolic process GO:0006720 45 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
neuron projection morphogenesis GO:0048812 122 0.013
Rat
syncytium formation GO:0006949 4 0.013
cell migration GO:0016477 197 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
cellular component morphogenesis GO:0032989 155 0.013
Rat
behavior GO:0007610 205 0.013
heterocycle catabolic process GO:0046700 167 0.013
aging GO:0007568 241 0.013
cellular response to insulin stimulus GO:0032869 81 0.013
axis specification GO:0009798 4 0.013
gliogenesis GO:0042063 93 0.013
response to hypoxia GO:0001666 231 0.012
regulation of secretion by cell GO:1903530 208 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
carboxylic acid biosynthetic process GO:0046394 83 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
negative regulation of innate immune response GO:0045824 4 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
Fly
alpha amino acid metabolic process GO:1901605 71 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
response to external biotic stimulus GO:0043207 221 0.012
cation transmembrane transport GO:0098655 263 0.012
response to amine GO:0014075 46 0.012
response to acid chemical GO:0001101 222 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
biological adhesion GO:0022610 110 0.012
photoperiodism GO:0009648 4 0.012
spermatogenesis GO:0007283 99 0.012
organic hydroxy compound biosynthetic process GO:1901617 51 0.012
Fly
regulation of response to wounding GO:1903034 69 0.012
ion homeostasis GO:0050801 212 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
regulation of kinase activity GO:0043549 117 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
protein transport GO:0015031 132 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.011
Fly
monovalent inorganic cation transport GO:0015672 172 0.011
regulation of potassium ion transport GO:0043266 29 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
dephosphorylation GO:0016311 98 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
purine containing compound catabolic process GO:0072523 138 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
rhythmic process GO:0048511 156 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
regulation of locomotion GO:0040012 148 0.011
response to heat GO:0009408 60 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
inflammatory response GO:0006954 150 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
cellular homeostasis GO:0019725 252 0.011
gland development GO:0048732 155 0.011
response to corticosteroid GO:0031960 235 0.011
regulation of lipid metabolic process GO:0019216 68 0.011
energy derivation by oxidation of organic compounds GO:0015980 46 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
wound healing GO:0042060 122 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
organic substance catabolic process GO:1901575 316 0.011
regulation of ion transmembrane transporter activity GO:0032412 48 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
protein maturation GO:0051604 68 0.011
positive regulation of transferase activity GO:0051347 81 0.011
regulation of ion transport GO:0043269 245 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
cellular ion homeostasis GO:0006873 184 0.010
localization of cell GO:0051674 202 0.010
cell type specific apoptotic process GO:0097285 134 0.010
potassium ion transport GO:0006813 97 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.010
Rat
calcium ion transport GO:0006816 131 0.010
coenzyme metabolic process GO:0006732 86 0.010
regulation of secretion GO:0051046 224 0.010
regulation of cell growth GO:0001558 85 0.010
negative regulation of cell projection organization GO:0031345 50 0.010
tissue development GO:0009888 252 0.010
sodium ion transport GO:0006814 82 0.010
regulation of immune response GO:0050776 55 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
steroid metabolic process GO:0008202 73 0.010
innate immune response GO:0045087 35 0.010
cyclic nucleotide metabolic process GO:0009187 80 0.010
regulation of protein serine threonine kinase activity GO:0071900 64 0.010
cell part morphogenesis GO:0032990 123 0.010
Rat

Itpkc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
Human
musculoskeletal system disease DOID:17 0 0.022
muscular disease DOID:0080000 0 0.016
muscle tissue disease DOID:66 0 0.016
myopathy DOID:423 0 0.014
nervous system disease DOID:863 0 0.013