Rattus norvegicus

11 known processes

Sorl1

sortilin-related receptor, LDLR class A repeats-containing

(Aliases: RGD619914,Lr11)

Sorl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.052
positive regulation of transcription dna templated GO:0045893 197 0.052
regulation of nucleic acid templated transcription GO:1903506 380 0.048
positive regulation of rna biosynthetic process GO:1902680 197 0.044
regulation of rna metabolic process GO:0051252 391 0.044
central nervous system development GO:0007417 311 0.042
positive regulation of neurogenesis GO:0050769 165 0.041
transcription dna templated GO:0006351 377 0.040
brain development GO:0007420 247 0.039
regulation of cellular component organization GO:0051128 368 0.038
rna biosynthetic process GO:0032774 380 0.034
heterocycle catabolic process GO:0046700 167 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
regulation of transcription dna templated GO:0006355 374 0.030
purine nucleoside triphosphate metabolic process GO:0009144 141 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
protein complex biogenesis GO:0070271 263 0.029
positive regulation of gene expression GO:0010628 244 0.029
neuron differentiation GO:0030182 368 0.029
apoptotic process GO:0006915 381 0.028
regulation of cell projection organization GO:0031344 175 0.028
cell projection organization GO:0030030 302 0.028
macromolecular complex assembly GO:0065003 273 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
nucleic acid templated transcription GO:0097659 379 0.027
regulation of neuron differentiation GO:0045664 208 0.027
rna metabolic process GO:0016070 406 0.027
negative regulation of metabolic process GO:0009892 331 0.027
regulation of nervous system development GO:0051960 264 0.026
cell cell signaling GO:0007267 335 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
nucleoside triphosphate metabolic process GO:0009141 144 0.024
regulation of cell development GO:0060284 263 0.024
regulation of cell differentiation GO:0045595 320 0.024
protein complex subunit organization GO:0071822 302 0.024
regulation of rna biosynthetic process GO:2001141 381 0.023
positive regulation of nervous system development GO:0051962 178 0.023
protein phosphorylation GO:0006468 345 0.023
organic acid metabolic process GO:0006082 292 0.023
regulation of signal transduction GO:0009966 318 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
protein complex assembly GO:0006461 263 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
intracellular signal transduction GO:0035556 314 0.023
macromolecular complex subunit organization GO:0043933 339 0.022
carboxylic acid metabolic process GO:0019752 289 0.022
regulation of apoptotic process GO:0042981 335 0.022
head development GO:0060322 247 0.022
intracellular transport GO:0046907 185 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
catabolic process GO:0009056 351 0.022
cellular component biogenesis GO:0044085 368 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
locomotion GO:0040011 237 0.022
single organism intracellular transport GO:1902582 166 0.022
neuron projection development GO:0031175 273 0.022
organic cyclic compound catabolic process GO:1901361 175 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
regulation of programmed cell death GO:0043067 341 0.021
positive regulation of developmental process GO:0051094 283 0.021
single organism catabolic process GO:0044712 283 0.020
positive regulation of cell development GO:0010720 176 0.020
ribonucleoside catabolic process GO:0042454 126 0.020
regulation of neurogenesis GO:0050767 247 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
nucleoside metabolic process GO:0009116 179 0.020
response to peptide hormone GO:0043434 278 0.020
response to extracellular stimulus GO:0009991 380 0.020
cation transport GO:0006812 382 0.020
ribonucleotide catabolic process GO:0009261 136 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.019
chemical homeostasis GO:0048878 292 0.019
regulation of neuron projection development GO:0010975 161 0.019
purine nucleoside metabolic process GO:0042278 169 0.019
response to peptide GO:1901652 292 0.019
establishment of protein localization GO:0045184 141 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
regulation of protein metabolic process GO:0051246 289 0.019
regulation of molecular function GO:0065009 398 0.018
motor neuron axon guidance GO:0008045 1 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
growth GO:0040007 165 0.018
dendrite development GO:0016358 72 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
neurological system process GO:0050877 219 0.018
protein transport GO:0015031 132 0.018
protein oligomerization GO:0051259 191 0.018
vesicle mediated transport GO:0016192 181 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.018
fatty acid metabolic process GO:0006631 99 0.018
organic substance catabolic process GO:1901575 316 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
behavior GO:0007610 205 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
synaptic transmission GO:0007268 235 0.017
monocarboxylic acid metabolic process GO:0032787 152 0.017
cell cycle GO:0007049 101 0.017
programmed cell death GO:0012501 392 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
cell morphogenesis GO:0000902 142 0.017
positive regulation of cell differentiation GO:0045597 217 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
cellular amine metabolic process GO:0044106 38 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
anterior posterior pattern specification GO:0009952 1 0.016
oxoacid metabolic process GO:0043436 290 0.016
cellular ketone metabolic process GO:0042180 51 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
negative regulation of signaling GO:0023057 157 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
multicellular organism growth GO:0035264 1 0.016
protein localization GO:0008104 191 0.016
multi organism reproductive process GO:0044703 262 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
positive regulation of neuron differentiation GO:0045666 126 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
response to monosaccharide GO:0034284 159 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
purine containing compound catabolic process GO:0072523 138 0.015
cellular component assembly GO:0022607 360 0.015
cellular component morphogenesis GO:0032989 155 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
regulation of membrane potential GO:0042391 110 0.015
response to glucose GO:0009749 136 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
cellular response to lipid GO:0071396 201 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
ras protein signal transduction GO:0007265 29 0.014
carbohydrate metabolic process GO:0005975 130 0.014
response to hexose GO:0009746 144 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
aromatic compound catabolic process GO:0019439 168 0.014
ion transmembrane transport GO:0034220 365 0.014
response to growth factor GO:0070848 189 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
action potential GO:0001508 54 0.014
transmission of nerve impulse GO:0019226 42 0.014
negative regulation of programmed cell death GO:0043069 183 0.013
nucleotide metabolic process GO:0009117 279 0.013
cell part morphogenesis GO:0032990 123 0.013
epithelium development GO:0060429 96 0.013
amine metabolic process GO:0009308 38 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
regulation of system process GO:0044057 208 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
neuronal action potential GO:0019228 35 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
regulation of protein localization GO:0032880 81 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
axis specification GO:0009798 4 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
homeostatic process GO:0042592 331 0.012
multicellular organismal signaling GO:0035637 44 0.012
ion homeostasis GO:0050801 212 0.012
defense response GO:0006952 194 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
cellular catabolic process GO:0044248 295 0.012
neuron projection morphogenesis GO:0048812 122 0.012
response to insulin GO:0032868 133 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
purine containing compound metabolic process GO:0072521 253 0.012
nucleotide catabolic process GO:0009166 139 0.012
multicellular organism reproduction GO:0032504 233 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
cell growth GO:0016049 104 0.012
response to acid chemical GO:0001101 222 0.012
gland development GO:0048732 155 0.011
tissue development GO:0009888 252 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
reproductive process GO:0022414 372 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
regulation of catabolic process GO:0009894 113 0.011
secretion GO:0046903 307 0.011
negative regulation of transport GO:0051051 136 0.011
positive regulation of molecular function GO:0044093 230 0.011
cell adhesion GO:0007155 110 0.011
signal release GO:0023061 145 0.011
reproduction GO:0000003 245 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
neuron development GO:0048666 286 0.011
insulin like growth factor receptor signaling pathway GO:0048009 3 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
negative regulation of molecular function GO:0044092 133 0.011
response to carbohydrate GO:0009743 183 0.011
nitrogen compound transport GO:0071705 229 0.011
negative regulation of gene expression GO:0010629 199 0.011
response to oxygen levels GO:0070482 265 0.011
cytoplasmic transport GO:0016482 115 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
cellular homeostasis GO:0019725 252 0.011
response to nutrient levels GO:0031667 370 0.011
single organism biosynthetic process GO:0044711 342 0.011
metal ion transport GO:0030001 289 0.011
cellular response to insulin stimulus GO:0032869 81 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
guanosine containing compound catabolic process GO:1901069 71 0.010
glycosyl compound catabolic process GO:1901658 126 0.010
potassium ion transport GO:0006813 97 0.010
regulation of protein transport GO:0051223 68 0.010
salivary gland development GO:0007431 3 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
cell projection morphogenesis GO:0048858 123 0.010
organelle organization GO:0006996 266 0.010
cellular response to endogenous stimulus GO:0071495 377 0.010
organophosphate catabolic process GO:0046434 148 0.010

Sorl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.019
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
disease of metabolism DOID:0014667 0 0.010