Rattus norvegicus

0 known processes

Flii

flightless I homolog (Drosophila)

(Aliases: Fliih,MGC94344)

Flii biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleoside phosphate metabolic process GO:0006753 283 0.227
transcription from rna polymerase ii promoter GO:0006366 252 0.159
organophosphate metabolic process GO:0019637 370 0.145
regulation of rna metabolic process GO:0051252 391 0.142
macromolecular complex assembly GO:0065003 273 0.120
nucleotide metabolic process GO:0009117 279 0.108
oxoacid metabolic process GO:0043436 290 0.102
carbohydrate derivative metabolic process GO:1901135 346 0.084
ribonucleoside catabolic process GO:0042454 126 0.084
nucleobase containing small molecule metabolic process GO:0055086 316 0.084
vesicle mediated transport GO:0016192 181 0.082
purine nucleoside metabolic process GO:0042278 169 0.081
regulation of rna biosynthetic process GO:2001141 381 0.079
rna metabolic process GO:0016070 406 0.076
macromolecular complex subunit organization GO:0043933 339 0.074
Rat
glycosyl compound catabolic process GO:1901658 126 0.071
nucleotide catabolic process GO:0009166 139 0.068
ribonucleotide metabolic process GO:0009259 231 0.067
purine nucleotide metabolic process GO:0006163 229 0.066
purine ribonucleoside catabolic process GO:0046130 124 0.065
nucleoside phosphate catabolic process GO:1901292 140 0.064
catabolic process GO:0009056 351 0.064
single organism catabolic process GO:0044712 283 0.063
aromatic compound catabolic process GO:0019439 168 0.063
organic cyclic compound catabolic process GO:1901361 175 0.060
organophosphate catabolic process GO:0046434 148 0.058
purine nucleotide catabolic process GO:0006195 136 0.057
ribose phosphate metabolic process GO:0019693 235 0.055
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.055
carbohydrate derivative catabolic process GO:1901136 147 0.053
purine ribonucleotide metabolic process GO:0009150 227 0.053
regulation of molecular function GO:0065009 398 0.052
nucleoside triphosphate catabolic process GO:0009143 123 0.051
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.051
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.050
positive regulation of transcription dna templated GO:0045893 197 0.050
purine nucleoside triphosphate metabolic process GO:0009144 141 0.049
endocytosis GO:0006897 84 0.049
organonitrogen compound catabolic process GO:1901565 179 0.049
macromolecule localization GO:0033036 252 0.049
purine nucleoside triphosphate catabolic process GO:0009146 122 0.048
cellular component assembly GO:0022607 360 0.048
nucleoside catabolic process GO:0009164 126 0.048
reproductive process GO:0022414 372 0.047
ribonucleoside triphosphate metabolic process GO:0009199 141 0.047
regulation of signal transduction GO:0009966 318 0.047
regulation of phosphate metabolic process GO:0019220 349 0.047
transcription dna templated GO:0006351 377 0.046
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.046
nucleoside triphosphate metabolic process GO:0009141 144 0.045
intracellular signal transduction GO:0035556 314 0.045
Rat
rna biosynthetic process GO:0032774 380 0.045
positive regulation of rna metabolic process GO:0051254 203 0.044
regulation of cellular component organization GO:0051128 368 0.044
purine ribonucleoside metabolic process GO:0046128 168 0.043
purine containing compound metabolic process GO:0072521 253 0.043
intracellular transport GO:0046907 185 0.043
positive regulation of biosynthetic process GO:0009891 319 0.041
regulation of nucleic acid templated transcription GO:1903506 380 0.041
cellular component biogenesis GO:0044085 368 0.040
response to metal ion GO:0010038 253 0.040
Rat
positive regulation of developmental process GO:0051094 283 0.040
protein phosphorylation GO:0006468 345 0.040
nucleoside metabolic process GO:0009116 179 0.037
positive regulation of cellular biosynthetic process GO:0031328 295 0.037
organic acid metabolic process GO:0006082 292 0.037
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.037
cellular nitrogen compound catabolic process GO:0044270 163 0.036
glycosyl compound metabolic process GO:1901657 182 0.036
developmental growth GO:0048589 100 0.036
Rat
purine nucleoside catabolic process GO:0006152 124 0.036
protein complex subunit organization GO:0071822 302 0.036
Rat
response to nutrient GO:0007584 248 0.035
Rat
growth GO:0040007 165 0.035
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.035
nucleobase containing compound catabolic process GO:0034655 152 0.035
cellular response to stress GO:0033554 269 0.035
heterocycle catabolic process GO:0046700 167 0.034
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
anatomical structure morphogenesis GO:0009653 298 0.034
purine ribonucleotide catabolic process GO:0009154 136 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.034
protein complex assembly GO:0006461 263 0.033
regulation of transcription dna templated GO:0006355 374 0.033
regulation of multicellular organismal development GO:2000026 376 0.033
positive regulation of phosphate metabolic process GO:0045937 262 0.033
cardiovascular system development GO:0072358 134 0.033
cellular catabolic process GO:0044248 295 0.033
response to peptide GO:1901652 292 0.032
single organism biosynthetic process GO:0044711 342 0.032
apoptotic process GO:0006915 381 0.031
Rat
cellular component movement GO:0006928 248 0.031
purine containing compound catabolic process GO:0072523 138 0.031
positive regulation of multicellular organismal process GO:0051240 387 0.031
ribonucleoside triphosphate catabolic process GO:0009203 122 0.031
regulation of nervous system development GO:0051960 264 0.031
response to acid chemical GO:0001101 222 0.031
Rat
multicellular organismal reproductive process GO:0048609 233 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.029
response to oxygen levels GO:0070482 265 0.029
carboxylic acid metabolic process GO:0019752 289 0.029
spindle organization GO:0007051 2 0.029
regulation of locomotion GO:0040012 148 0.029
regulation of cellular localization GO:0060341 263 0.028
nucleic acid templated transcription GO:0097659 379 0.028
regulation of catalytic activity GO:0050790 304 0.028
organic substance catabolic process GO:1901575 316 0.028
cell growth GO:0016049 104 0.028
positive regulation of protein modification process GO:0031401 142 0.028
response to inorganic substance GO:0010035 377 0.028
Rat
cytoplasmic transport GO:0016482 115 0.028
protein oligomerization GO:0051259 191 0.028
enzyme linked receptor protein signaling pathway GO:0007167 116 0.028
aging GO:0007568 241 0.027
Rat
ribonucleoside monophosphate metabolic process GO:0009161 88 0.027
protein complex biogenesis GO:0070271 263 0.027
multi organism reproductive process GO:0044703 262 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
cellular ketone metabolic process GO:0042180 51 0.027
regulation of cell growth GO:0001558 85 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
negative regulation of response to stimulus GO:0048585 155 0.026
regulation of neurogenesis GO:0050767 247 0.025
cellular amine metabolic process GO:0044106 38 0.025
negative regulation of cell communication GO:0010648 158 0.025
regulation of cell proliferation GO:0042127 359 0.025
regulation of phosphorylation GO:0042325 248 0.024
single organism carbohydrate metabolic process GO:0044723 118 0.024
tissue development GO:0009888 252 0.024
Rat
response to peptide hormone GO:0043434 278 0.024
regulation of growth GO:0040008 105 0.023
positive regulation of gene expression GO:0010628 244 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
nucleoside phosphate biosynthetic process GO:1901293 102 0.023
single organism intracellular transport GO:1902582 166 0.023
multicellular organism growth GO:0035264 1 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.023
nucleoside monophosphate catabolic process GO:0009125 56 0.023
amine metabolic process GO:0009308 38 0.023
epithelium development GO:0060429 96 0.023
regulation of protein metabolic process GO:0051246 289 0.023
negative regulation of signal transduction GO:0009968 83 0.023
cation homeostasis GO:0055080 195 0.023
locomotion GO:0040011 237 0.023
atp catabolic process GO:0006200 54 0.022
response to growth factor GO:0070848 189 0.022
single organism organelle organization GO:1902589 180 0.022
Rat
cellular amino acid metabolic process GO:0006520 107 0.022
cation transport GO:0006812 382 0.022
regulation of transporter activity GO:0032409 50 0.022
regulation of cell migration GO:0030334 128 0.022
reproduction GO:0000003 245 0.022
ribonucleotide catabolic process GO:0009261 136 0.022
positive regulation of cellular protein metabolic process GO:0032270 167 0.022
organelle organization GO:0006996 266 0.022
Rat
regulation of cell differentiation GO:0045595 320 0.022
insulin like growth factor receptor signaling pathway GO:0048009 3 0.022
ribonucleoside metabolic process GO:0009119 174 0.022
central nervous system development GO:0007417 311 0.021
Rat
cell projection organization GO:0030030 302 0.021
cellular component morphogenesis GO:0032989 155 0.021
cellular response to organonitrogen compound GO:0071417 197 0.021
transmembrane transport GO:0055085 412 0.021
cellular homeostasis GO:0019725 252 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
purine nucleoside monophosphate metabolic process GO:0009126 84 0.021
negative regulation of cellular component organization GO:0051129 83 0.020
homeostatic process GO:0042592 331 0.020
negative regulation of metabolic process GO:0009892 331 0.020
g protein coupled receptor signaling pathway GO:0007186 242 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
protein heterooligomerization GO:0051291 89 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
ion homeostasis GO:0050801 212 0.019
inorganic cation transmembrane transport GO:0098662 202 0.019
ion transmembrane transport GO:0034220 365 0.019
divalent inorganic cation transport GO:0072511 134 0.019
neuron projection development GO:0031175 273 0.019
cell motility GO:0048870 202 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
circulatory system development GO:0072359 134 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
purine nucleoside monophosphate catabolic process GO:0009128 55 0.019
cellular response to oxygen containing compound GO:1901701 386 0.018
response to extracellular stimulus GO:0009991 380 0.018
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.018
positive regulation of molecular function GO:0044093 230 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
negative regulation of cell development GO:0010721 82 0.018
divalent metal ion transport GO:0070838 132 0.018
positive regulation of transport GO:0051050 245 0.018
cellular chemical homeostasis GO:0055082 247 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.018
chromosome segregation GO:0007059 2 0.018
regulation of nucleotide catabolic process GO:0030811 65 0.017
proteolysis GO:0006508 175 0.017
ras protein signal transduction GO:0007265 29 0.017
positive regulation of nervous system development GO:0051962 178 0.017
regulation of catabolic process GO:0009894 113 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
positive regulation of cell death GO:0010942 184 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
synaptic growth at neuromuscular junction GO:0051124 1 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
regulation of cellular component movement GO:0051270 150 0.017
response to alkaloid GO:0043279 132 0.016
single organism cellular localization GO:1902580 102 0.016
chemical homeostasis GO:0048878 292 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
negative regulation of signaling GO:0023057 157 0.016
lipid metabolic process GO:0006629 283 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
metal ion homeostasis GO:0055065 186 0.016
liver development GO:0001889 90 0.016
cellular ion homeostasis GO:0006873 184 0.016
gliogenesis GO:0042063 93 0.016
Rat
regulation of cellular catabolic process GO:0031329 101 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
atp metabolic process GO:0046034 72 0.016
protein import into nucleus GO:0006606 35 0.016
response to estradiol GO:0032355 164 0.016
multicellular organism reproduction GO:0032504 233 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
nucleotide biosynthetic process GO:0009165 98 0.015
response to hypoxia GO:0001666 231 0.015
regulation of hydrolase activity GO:0051336 143 0.015
negative regulation of insulin receptor signaling pathway GO:0046627 10 0.015
circulatory system process GO:0003013 183 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
regulation of cell motility GO:2000145 131 0.015
cellular cation homeostasis GO:0030003 180 0.015
carbohydrate metabolic process GO:0005975 130 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
response to nutrient levels GO:0031667 370 0.015
Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
immune system process GO:0002376 204 0.015
response to estrogen GO:0043627 232 0.015
protein homooligomerization GO:0051260 91 0.015
negative regulation of molecular function GO:0044092 133 0.015
gland development GO:0048732 155 0.015
neuron differentiation GO:0030182 368 0.015
cell part morphogenesis GO:0032990 123 0.015
cellular response to endogenous stimulus GO:0071495 377 0.015
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
rhythmic process GO:0048511 156 0.014
negative regulation of gene expression GO:0010629 199 0.014
single organism reproductive process GO:0044702 297 0.014
sexual reproduction GO:0019953 148 0.014
regulation of mapk cascade GO:0043408 116 0.014
axon development GO:0061564 96 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
heart development GO:0007507 72 0.014
head development GO:0060322 247 0.014
response to mechanical stimulus GO:0009612 134 0.014
positive regulation of cell development GO:0010720 176 0.014
calcium ion homeostasis GO:0055074 162 0.014
nuclear transport GO:0051169 49 0.014
secretion by cell GO:0032940 248 0.014
brain development GO:0007420 247 0.013
cation transmembrane transport GO:0098655 263 0.013
positive regulation of nucleoside metabolic process GO:0045979 55 0.013
axis specification GO:0009798 4 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
gamete generation GO:0007276 124 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
metal ion transport GO:0030001 289 0.013
regulation of protein localization GO:0032880 81 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
positive regulation of growth GO:0045927 55 0.013
response to cytokine GO:0034097 215 0.013
regulation of apoptotic process GO:0042981 335 0.013
programmed cell death GO:0012501 392 0.013
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
response to carbohydrate GO:0009743 183 0.013
nitrogen compound transport GO:0071705 229 0.013
peptidyl amino acid modification GO:0018193 126 0.013
intracellular protein transport GO:0006886 79 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
regulation of developmental growth GO:0048638 45 0.013
axonogenesis GO:0007409 71 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
defense response GO:0006952 194 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
actin filament based process GO:0030029 86 0.012
Rat
hepaticobiliary system development GO:0061008 90 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
ribonucleoside monophosphate catabolic process GO:0009158 55 0.012
multi multicellular organism process GO:0044706 138 0.012
negative regulation of cellular response to insulin stimulus GO:1900077 11 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
chromatin organization GO:0006325 34 0.012
receptor mediated endocytosis GO:0006898 42 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
neuron projection morphogenesis GO:0048812 122 0.012
protein transport GO:0015031 132 0.012
response to bacterium GO:0009617 200 0.012
nucleoside monophosphate metabolic process GO:0009123 93 0.012
cytoskeleton organization GO:0007010 111 0.012
Rat
muscle structure development GO:0061061 87 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
single organism nuclear import GO:1902593 35 0.011
nuclear import GO:0051170 35 0.011
regulation of secretion by cell GO:1903530 208 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
organic hydroxy compound transport GO:0015850 77 0.011
regulation of gtpase activity GO:0043087 57 0.011
protein localization GO:0008104 191 0.011
response to insulin GO:0032868 133 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
dendrite development GO:0016358 72 0.011
maintenance of location GO:0051235 17 0.011
establishment of protein localization GO:0045184 141 0.011
response to external biotic stimulus GO:0043207 221 0.011
cell migration GO:0016477 197 0.011
inflammatory response GO:0006954 150 0.011
female pregnancy GO:0007565 122 0.011
nucleocytoplasmic transport GO:0006913 48 0.011
positive regulation of nucleotide catabolic process GO:0030813 53 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
protein localization to nucleus GO:0034504 39 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
regulation of programmed cell death GO:0043067 341 0.011
negative regulation of developmental process GO:0051093 125 0.011
negative regulation of growth GO:0045926 37 0.011
regulation of anatomical structure size GO:0090066 135 0.011
cell morphogenesis GO:0000902 142 0.010
establishment of protein localization to organelle GO:0072594 44 0.010
microtubule cytoskeleton organization GO:0000226 25 0.010
protein targeting to nucleus GO:0044744 35 0.010
small molecule biosynthetic process GO:0044283 124 0.010
muscle system process GO:0003012 115 0.010
gtp catabolic process GO:0006184 71 0.010

Flii disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.041
muscular disease DOID:0080000 0 0.041
muscular dystrophy DOID:9884 0 0.041
disease of anatomical entity DOID:7 0 0.041
musculoskeletal system disease DOID:17 0 0.041
muscle tissue disease DOID:66 0 0.041
nervous system disease DOID:863 0 0.031
sensory system disease DOID:0050155 0 0.013
central nervous system disease DOID:331 0 0.011
cardiovascular system disease DOID:1287 0 0.010