Rattus norvegicus

0 known processes

Zfhx4

zinc finger homeobox 4

(Aliases: RGD1563022)

Zfhx4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of multicellular organismal process GO:0051240 387 0.086
regulation of transcription dna templated GO:0006355 374 0.083
regulation of rna biosynthetic process GO:2001141 381 0.079
transcription dna templated GO:0006351 377 0.071
nucleic acid templated transcription GO:0097659 379 0.069
brain development GO:0007420 247 0.067
cellular response to endogenous stimulus GO:0071495 377 0.065
rna biosynthetic process GO:0032774 380 0.065
cellular response to oxygen containing compound GO:1901701 386 0.064
positive regulation of cellular biosynthetic process GO:0031328 295 0.063
regulation of cell differentiation GO:0045595 320 0.063
intracellular signal transduction GO:0035556 314 0.060
cellular component biogenesis GO:0044085 368 0.056
cellular response to hormone stimulus GO:0032870 247 0.055
positive regulation of biosynthetic process GO:0009891 319 0.054
rna metabolic process GO:0016070 406 0.053
cellular response to organic cyclic compound GO:0071407 202 0.052
macromolecular complex subunit organization GO:0043933 339 0.051
regulation of signal transduction GO:0009966 318 0.050
protein complex subunit organization GO:0071822 302 0.049
positive regulation of neurogenesis GO:0050769 165 0.049
regulation of nucleic acid templated transcription GO:1903506 380 0.048
regulation of rna metabolic process GO:0051252 391 0.048
protein phosphorylation GO:0006468 345 0.047
positive regulation of rna biosynthetic process GO:1902680 197 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.047
regulation of cell development GO:0060284 263 0.047
positive regulation of transcription dna templated GO:0045893 197 0.046
response to extracellular stimulus GO:0009991 380 0.046
cell projection organization GO:0030030 302 0.046
cellular component movement GO:0006928 248 0.046
neuron differentiation GO:0030182 368 0.045
single organism reproductive process GO:0044702 297 0.045
positive regulation of developmental process GO:0051094 283 0.043
regulation of cellular component organization GO:0051128 368 0.043
regulation of cell proliferation GO:0042127 359 0.043
regulation of multicellular organismal development GO:2000026 376 0.042
central nervous system development GO:0007417 311 0.042
regulation of molecular function GO:0065009 398 0.042
tissue development GO:0009888 252 0.042
negative regulation of signaling GO:0023057 157 0.042
cation transport GO:0006812 382 0.041
cellular response to lipid GO:0071396 201 0.041
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.041
regulation of cellular ketone metabolic process GO:0010565 27 0.040
organic acid metabolic process GO:0006082 292 0.040
cell cell signaling GO:0007267 335 0.040
positive regulation of cell differentiation GO:0045597 217 0.039
transcription from rna polymerase ii promoter GO:0006366 252 0.039
positive regulation of nucleic acid templated transcription GO:1903508 197 0.038
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.038
multicellular organism reproduction GO:0032504 233 0.038
localization of cell GO:0051674 202 0.038
positive regulation of gene expression GO:0010628 244 0.037
regulation of cellular amino acid metabolic process GO:0006521 2 0.037
regulation of nervous system development GO:0051960 264 0.037
carboxylic acid metabolic process GO:0019752 289 0.037
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.037
positive regulation of response to stimulus GO:0048584 285 0.036
cellular amino acid metabolic process GO:0006520 107 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.035
regulation of cellular protein metabolic process GO:0032268 267 0.034
positive regulation of signal transduction GO:0009967 175 0.034
positive regulation of rna metabolic process GO:0051254 203 0.034
anatomical structure morphogenesis GO:0009653 298 0.033
regulation of neurogenesis GO:0050767 247 0.033
neuron development GO:0048666 286 0.033
positive regulation of nervous system development GO:0051962 178 0.033
positive regulation of cell projection organization GO:0031346 111 0.033
regulation of phosphorylation GO:0042325 248 0.033
cellular amine metabolic process GO:0044106 38 0.033
transmembrane transport GO:0055085 412 0.032
positive regulation of signaling GO:0023056 270 0.032
regulation of cellular amine metabolic process GO:0033238 8 0.032
positive regulation of cell communication GO:0010647 271 0.032
gland development GO:0048732 155 0.031
regulation of neuron differentiation GO:0045664 208 0.031
multicellular organismal reproductive process GO:0048609 233 0.031
response to nutrient GO:0007584 248 0.031
head development GO:0060322 247 0.031
positive regulation of cellular component organization GO:0051130 200 0.031
reproductive process GO:0022414 372 0.031
response to peptide hormone GO:0043434 278 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
cellular component assembly GO:0022607 360 0.030
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.030
macromolecular complex assembly GO:0065003 273 0.030
cell migration GO:0016477 197 0.030
regulation of system process GO:0044057 208 0.030
regulation of cellular localization GO:0060341 263 0.029
synaptic transmission GO:0007268 235 0.029
protein complex assembly GO:0006461 263 0.029
regulation of phosphate metabolic process GO:0019220 349 0.028
neuron projection development GO:0031175 273 0.028
response to nutrient levels GO:0031667 370 0.028
single organism biosynthetic process GO:0044711 342 0.028
positive regulation of transport GO:0051050 245 0.028
reproduction GO:0000003 245 0.028
amine metabolic process GO:0009308 38 0.028
regulation of intracellular signal transduction GO:1902531 218 0.028
negative regulation of gene expression GO:0010629 199 0.027
protein complex biogenesis GO:0070271 263 0.027
ion transmembrane transport GO:0034220 365 0.027
cellular homeostasis GO:0019725 252 0.027
cellular ketone metabolic process GO:0042180 51 0.027
nitrogen compound transport GO:0071705 229 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
positive regulation of cell development GO:0010720 176 0.027
response to peptide GO:1901652 292 0.027
positive regulation of cell proliferation GO:0008284 249 0.026
mapk cascade GO:0000165 140 0.026
cellular response to organonitrogen compound GO:0071417 197 0.026
negative regulation of cellular biosynthetic process GO:0031327 161 0.026
response to corticosteroid GO:0031960 235 0.026
locomotion GO:0040011 237 0.026
regulation of programmed cell death GO:0043067 341 0.026
response to ketone GO:1901654 182 0.026
cellular response to nitrogen compound GO:1901699 210 0.026
divalent inorganic cation transport GO:0072511 134 0.026
regulation of apoptotic process GO:0042981 335 0.026
response to estrogen GO:0043627 232 0.025
protein localization GO:0008104 191 0.025
nucleotide metabolic process GO:0009117 279 0.025
negative regulation of metabolic process GO:0009892 331 0.025
positive regulation of neuron projection development GO:0010976 99 0.024
response to estradiol GO:0032355 164 0.024
response to acid chemical GO:0001101 222 0.024
metal ion transport GO:0030001 289 0.024
cell morphogenesis GO:0000902 142 0.024
anterior posterior pattern specification GO:0009952 1 0.024
organophosphate metabolic process GO:0019637 370 0.023
catabolic process GO:0009056 351 0.023
programmed cell death GO:0012501 392 0.023
regulation of protein phosphorylation GO:0001932 183 0.023
negative regulation of cell communication GO:0010648 158 0.023
homeostatic process GO:0042592 331 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
single organism organelle organization GO:1902589 180 0.023
regulation of neuron projection development GO:0010975 161 0.023
macromolecule localization GO:0033036 252 0.023
signal transduction by phosphorylation GO:0023014 144 0.023
response to glucocorticoid GO:0051384 223 0.023
cellular response to alcohol GO:0097306 87 0.023
developmental process involved in reproduction GO:0003006 159 0.022
regulation of protein metabolic process GO:0051246 289 0.022
organ formation GO:0048645 3 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
positive regulation of intracellular signal transduction GO:1902533 138 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
positive regulation of molecular function GO:0044093 230 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
mesoderm development GO:0007498 2 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.022
rhythmic process GO:0048511 156 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
regulation of membrane potential GO:0042391 110 0.021
aging GO:0007568 241 0.021
sexual reproduction GO:0019953 148 0.021
cellular response to stress GO:0033554 269 0.021
regulation of cell projection organization GO:0031344 175 0.021
protein oligomerization GO:0051259 191 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
multi organism reproductive process GO:0044703 262 0.021
response to inorganic substance GO:0010035 377 0.021
gastrulation GO:0007369 2 0.021
cell motility GO:0048870 202 0.020
multicellular organism growth GO:0035264 1 0.020
negative regulation of cell differentiation GO:0045596 99 0.020
regulation of transferase activity GO:0051338 123 0.020
regulation of catalytic activity GO:0050790 304 0.020
blood circulation GO:0008015 183 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
organic substance catabolic process GO:1901575 316 0.020
response to vitamin GO:0033273 131 0.020
embryonic skeletal system development GO:0048706 3 0.020
response to wounding GO:0009611 254 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
hormone transport GO:0009914 121 0.019
regulation of protein modification process GO:0031399 194 0.019
calcium ion homeostasis GO:0055074 162 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
single organism catabolic process GO:0044712 283 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
lipid metabolic process GO:0006629 283 0.019
apoptotic process GO:0006915 381 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
purine containing compound metabolic process GO:0072521 253 0.018
ion homeostasis GO:0050801 212 0.018
negative regulation of molecular function GO:0044092 133 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
cellular response to peptide hormone stimulus GO:0071375 120 0.018
response to cytokine GO:0034097 215 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.017
regulation of hormone levels GO:0010817 187 0.017
regulation of kinase activity GO:0043549 117 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
cellular ion homeostasis GO:0006873 184 0.017
response to hypoxia GO:0001666 231 0.017
axis specification GO:0009798 4 0.017
positive regulation of mapk cascade GO:0043410 92 0.017
tube development GO:0035295 89 0.017
development of primary sexual characteristics GO:0045137 107 0.017
organelle organization GO:0006996 266 0.017
oxoacid metabolic process GO:0043436 290 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
cellular catabolic process GO:0044248 295 0.017
regulation of canonical wnt signaling pathway GO:0060828 4 0.016
cation transmembrane transport GO:0098655 263 0.016
multi multicellular organism process GO:0044706 138 0.016
cation homeostasis GO:0055080 195 0.016
cellular chemical homeostasis GO:0055082 247 0.016
actin filament based process GO:0030029 86 0.016
synaptic growth at neuromuscular junction GO:0051124 1 0.016
cellular protein localization GO:0034613 122 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
growth GO:0040007 165 0.016
negative regulation of nervous system development GO:0051961 79 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
cellular macromolecule localization GO:0070727 122 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
cellular response to peptide GO:1901653 133 0.016
cellular response to glucocorticoid stimulus GO:0071385 68 0.015
negative regulation of developmental process GO:0051093 125 0.015
reproductive structure development GO:0048608 128 0.015
negative regulation of cell development GO:0010721 82 0.015
ras protein signal transduction GO:0007265 29 0.015
organic acid transport GO:0015849 116 0.015
salivary gland development GO:0007431 3 0.015
negative regulation of signal transduction GO:0009968 83 0.015
muscle system process GO:0003012 115 0.015
regulation of mapk cascade GO:0043408 116 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
action potential GO:0001508 54 0.015
response to oxygen levels GO:0070482 265 0.015
regulation of locomotion GO:0040012 148 0.015
cellular response to steroid hormone stimulus GO:0071383 93 0.015
regulation of synaptic transmission GO:0050804 141 0.015
neuron projection morphogenesis GO:0048812 122 0.015
cardiovascular system development GO:0072358 134 0.015
metal ion homeostasis GO:0055065 186 0.015
neuron death GO:0070997 127 0.015
cellular cation homeostasis GO:0030003 180 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
transmission of nerve impulse GO:0019226 42 0.015
chemical homeostasis GO:0048878 292 0.015
gamete generation GO:0007276 124 0.015
sex differentiation GO:0007548 113 0.015
ribose phosphate metabolic process GO:0019693 235 0.014
response to growth factor GO:0070848 189 0.014
negative regulation of cell death GO:0060548 229 0.014
embryonic skeletal system morphogenesis GO:0048704 3 0.014
regulation of muscle system process GO:0090257 79 0.014
neuronal action potential GO:0019228 35 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
hormone secretion GO:0046879 115 0.014
response to monosaccharide GO:0034284 159 0.014
reproductive system development GO:0061458 128 0.014
amide transport GO:0042886 105 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
forebrain development GO:0030900 98 0.014
negative regulation of transport GO:0051051 136 0.014
wound healing GO:0042060 122 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
anion transport GO:0006820 178 0.013
multicellular organismal signaling GO:0035637 44 0.013
intracellular transport GO:0046907 185 0.013
behavior GO:0007610 205 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
gonad development GO:0008406 104 0.013
vesicle mediated transport GO:0016192 181 0.013
biological adhesion GO:0022610 110 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
response to hexose GO:0009746 144 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
regulation of protein kinase activity GO:0045859 105 0.013
regulation of cell cycle GO:0051726 73 0.013
peptide transport GO:0015833 97 0.013
embryonic pattern specification GO:0009880 1 0.013
regulation of growth GO:0040008 105 0.013
response to carbohydrate GO:0009743 183 0.013
proteolysis GO:0006508 175 0.013
regulation of stem cell differentiation GO:2000736 2 0.013
response to ethanol GO:0045471 162 0.013
embryo development GO:0009790 49 0.013
epithelium development GO:0060429 96 0.013
chromosome segregation GO:0007059 2 0.013
dephosphorylation GO:0016311 98 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
response to decreased oxygen levels GO:0036293 237 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
oxidation reduction process GO:0055114 304 0.013
negative regulation of osteoblast differentiation GO:0045668 2 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
carbohydrate metabolic process GO:0005975 130 0.012
secretion GO:0046903 307 0.012
secretion by cell GO:0032940 248 0.012
divalent metal ion transport GO:0070838 132 0.012
cytoplasmic transport GO:0016482 115 0.012
activation of protein kinase activity GO:0032147 47 0.012
single organism intracellular transport GO:1902582 166 0.012
aromatic compound catabolic process GO:0019439 168 0.012
single organism cellular localization GO:1902580 102 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
regeneration GO:0031099 163 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
response to amine GO:0014075 46 0.012
calcium ion transport GO:0006816 131 0.012
establishment of protein localization GO:0045184 141 0.012
signal release GO:0023061 145 0.012
sensory perception GO:0007600 101 0.012
axon development GO:0061564 96 0.012
regulation of peptide hormone secretion GO:0090276 80 0.012
cytoskeleton organization GO:0007010 111 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
heterocycle catabolic process GO:0046700 167 0.012
cellular component morphogenesis GO:0032989 155 0.012
salivary gland morphogenesis GO:0007435 1 0.012
peptide hormone secretion GO:0030072 84 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
eye morphogenesis GO:0048592 4 0.012
cellular response to acid chemical GO:0071229 75 0.011
response to metal ion GO:0010038 253 0.011
regulation of hormone secretion GO:0046883 106 0.011
response to glucose GO:0009749 136 0.011
regulation of ion transport GO:0043269 245 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
cellular response to corticosteroid stimulus GO:0071384 69 0.011
regulation of peptide transport GO:0090087 87 0.011
response to external biotic stimulus GO:0043207 221 0.011
cell activation GO:0001775 97 0.011
striated muscle tissue development GO:0014706 58 0.011
circulatory system development GO:0072359 134 0.011
heart morphogenesis GO:0003007 3 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
response to mechanical stimulus GO:0009612 134 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
cellular response to ketone GO:1901655 51 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
regulation of cellular component movement GO:0051270 150 0.011
regulation of response to stress GO:0080134 126 0.011
cell growth GO:0016049 104 0.011
lipid storage GO:0019915 1 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
cell cycle GO:0007049 101 0.011
regulation of calcium ion transport GO:0051924 77 0.011
morphogenesis of embryonic epithelium GO:0016331 3 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
response to radiation GO:0009314 137 0.011
regulation of secretion by cell GO:1903530 208 0.011
positive regulation of protein modification process GO:0031401 142 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
cell projection morphogenesis GO:0048858 123 0.011
regulation of response to external stimulus GO:0032101 106 0.011
muscle cell proliferation GO:0033002 84 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
carboxylic acid transport GO:0046942 115 0.011
response to insulin GO:0032868 133 0.011
dna metabolic process GO:0006259 96 0.011
organic hydroxy compound transport GO:0015850 77 0.011
regulation of secretion GO:0051046 224 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
inorganic cation transmembrane transport GO:0098662 202 0.010
protein transport GO:0015031 132 0.010
cell fate determination GO:0001709 2 0.010
small molecule biosynthetic process GO:0044283 124 0.010
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
peptidyl amino acid modification GO:0018193 126 0.010
smooth muscle cell proliferation GO:0048659 77 0.010
regulation of anatomical structure size GO:0090066 135 0.010
positive regulation of kinase activity GO:0033674 77 0.010
formation of primary germ layer GO:0001704 1 0.010
dendrite development GO:0016358 72 0.010
regulation of protein localization GO:0032880 81 0.010
male gamete generation GO:0048232 99 0.010
regulation of smooth muscle cell proliferation GO:0048660 75 0.010
regulation of neuron death GO:1901214 115 0.010
inflammatory response GO:0006954 150 0.010
maintenance of location GO:0051235 17 0.010
regulation of protein transport GO:0051223 68 0.010
regulation of metal ion transport GO:0010959 118 0.010
purine nucleotide biosynthetic process GO:0006164 83 0.010
positive regulation of cell death GO:0010942 184 0.010
cellular lipid metabolic process GO:0044255 208 0.010
chemosensory behavior GO:0007635 2 0.010

Zfhx4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
musculoskeletal system disease DOID:17 0 0.014
central nervous system disease DOID:331 0 0.013
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010