Rattus norvegicus

43 known processes

Sts

steroid sulfatase

Sts biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to endogenous stimulus GO:0071495 377 0.200
single organism biosynthetic process GO:0044711 342 0.159
programmed cell death GO:0012501 392 0.145
apoptotic process GO:0006915 381 0.130
response to biotic stimulus GO:0009607 226 0.123
response to peptide GO:1901652 292 0.121
organic acid metabolic process GO:0006082 292 0.110
response to other organism GO:0051707 220 0.104
rna metabolic process GO:0016070 406 0.103
cellular lipid metabolic process GO:0044255 208 0.098
regulation of cell proliferation GO:0042127 359 0.098
response to extracellular stimulus GO:0009991 380 0.091
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.089
negative regulation of metabolic process GO:0009892 331 0.089
regulation of programmed cell death GO:0043067 341 0.088
response to nutrient levels GO:0031667 370 0.086
Rat
regulation of protein metabolic process GO:0051246 289 0.084
response to nutrient GO:0007584 248 0.077
Rat
regulation of apoptotic process GO:0042981 335 0.076
response to peptide hormone GO:0043434 278 0.076
positive regulation of gene expression GO:0010628 244 0.075
homeostatic process GO:0042592 331 0.075
positive regulation of cellular biosynthetic process GO:0031328 295 0.073
regulation of catalytic activity GO:0050790 304 0.071
regulation of nucleic acid templated transcription GO:1903506 380 0.070
positive regulation of transport GO:0051050 245 0.070
regulation of signal transduction GO:0009966 318 0.070
nucleic acid templated transcription GO:0097659 379 0.068
rna biosynthetic process GO:0032774 380 0.067
chemical homeostasis GO:0048878 292 0.066
carboxylic acid metabolic process GO:0019752 289 0.066
regulation of intracellular signal transduction GO:1902531 218 0.065
protein phosphorylation GO:0006468 345 0.064
secretion GO:0046903 307 0.063
transmembrane transport GO:0055085 412 0.062
intracellular signal transduction GO:0035556 314 0.061
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.061
regulation of phosphorus metabolic process GO:0051174 349 0.061
catabolic process GO:0009056 351 0.061
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.060
regulation of phosphorylation GO:0042325 248 0.059
response to cytokine GO:0034097 215 0.059
cellular response to oxygen containing compound GO:1901701 386 0.058
negative regulation of cell death GO:0060548 229 0.058
oxoacid metabolic process GO:0043436 290 0.057
cellular amino acid metabolic process GO:0006520 107 0.057
negative regulation of gene expression GO:0010629 199 0.057
response to bacterium GO:0009617 200 0.056
response to external biotic stimulus GO:0043207 221 0.056
negative regulation of macromolecule metabolic process GO:0010605 260 0.055
regulation of secretion GO:0051046 224 0.055
lipid biosynthetic process GO:0008610 128 0.055
regulation of molecular function GO:0065009 398 0.055
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.054
positive regulation of biosynthetic process GO:0009891 319 0.053
lipid metabolic process GO:0006629 283 0.053
positive regulation of cellular protein metabolic process GO:0032270 167 0.053
reproductive process GO:0022414 372 0.051
regulation of multicellular organismal development GO:2000026 376 0.050
positive regulation of phosphate metabolic process GO:0045937 262 0.050
positive regulation of rna metabolic process GO:0051254 203 0.050
regulation of protein phosphorylation GO:0001932 183 0.049
cellular response to stress GO:0033554 269 0.048
protein oligomerization GO:0051259 191 0.047
amine metabolic process GO:0009308 38 0.047
positive regulation of signaling GO:0023056 270 0.046
cellular catabolic process GO:0044248 295 0.046
Rat
regulation of cellular localization GO:0060341 263 0.045
negative regulation of cellular biosynthetic process GO:0031327 161 0.045
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.045
regulation of rna metabolic process GO:0051252 391 0.045
macromolecule localization GO:0033036 252 0.045
enzyme linked receptor protein signaling pathway GO:0007167 116 0.044
neuron death GO:0070997 127 0.044
regulation of phosphate metabolic process GO:0019220 349 0.044
positive regulation of transcription dna templated GO:0045893 197 0.043
organophosphate metabolic process GO:0019637 370 0.043
positive regulation of phosphorus metabolic process GO:0010562 262 0.043
transcription from rna polymerase ii promoter GO:0006366 252 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
nitrogen compound transport GO:0071705 229 0.042
single organism catabolic process GO:0044712 283 0.042
immune system process GO:0002376 204 0.042
regulation of cell differentiation GO:0045595 320 0.042
cellular component assembly GO:0022607 360 0.042
regulation of secretion by cell GO:1903530 208 0.042
regulation of ion transport GO:0043269 245 0.042
tissue development GO:0009888 252 0.041
defense response GO:0006952 194 0.041
reproduction GO:0000003 245 0.041
cellular response to hormone stimulus GO:0032870 247 0.041
response to hypoxia GO:0001666 231 0.041
cellular amine metabolic process GO:0044106 38 0.040
positive regulation of cell death GO:0010942 184 0.040
regulation of cellular component organization GO:0051128 368 0.040
single organism reproductive process GO:0044702 297 0.039
protein complex assembly GO:0006461 263 0.039
regulation of protein modification process GO:0031399 194 0.039
neurological system process GO:0050877 219 0.038
regulation of rna biosynthetic process GO:2001141 381 0.038
positive regulation of molecular function GO:0044093 230 0.038
transcription dna templated GO:0006351 377 0.038
cation transmembrane transport GO:0098655 263 0.037
cellular homeostasis GO:0019725 252 0.037
secretion by cell GO:0032940 248 0.037
response to insulin GO:0032868 133 0.037
response to decreased oxygen levels GO:0036293 237 0.036
cation transport GO:0006812 382 0.036
positive regulation of programmed cell death GO:0043068 157 0.036
multicellular organism reproduction GO:0032504 233 0.036
negative regulation of signaling GO:0023057 157 0.036
cellular ketone metabolic process GO:0042180 51 0.036
protein complex biogenesis GO:0070271 263 0.035
macromolecular complex subunit organization GO:0043933 339 0.035
positive regulation of developmental process GO:0051094 283 0.035
negative regulation of cell communication GO:0010648 158 0.035
macromolecular complex assembly GO:0065003 273 0.035
inflammatory response GO:0006954 150 0.034
cellular response to nitrogen compound GO:1901699 210 0.034
regulation of transcription dna templated GO:0006355 374 0.034
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.034
negative regulation of programmed cell death GO:0043069 183 0.034
vascular process in circulatory system GO:0003018 96 0.034
response to lipopolysaccharide GO:0032496 191 0.034
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.033
negative regulation of nucleic acid templated transcription GO:1903507 117 0.033
positive regulation of nervous system development GO:0051962 178 0.033
regulation of response to external stimulus GO:0032101 106 0.032
alpha amino acid metabolic process GO:1901605 71 0.032
multi organism reproductive process GO:0044703 262 0.031
cellular response to insulin stimulus GO:0032869 81 0.031
positive regulation of phosphorylation GO:0042327 177 0.031
negative regulation of transcription dna templated GO:0045892 116 0.030
cell cell signaling GO:0007267 335 0.030
response to acid chemical GO:0001101 222 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
cation homeostasis GO:0055080 195 0.030
protein complex subunit organization GO:0071822 302 0.030
response to metal ion GO:0010038 253 0.030
organonitrogen compound biosynthetic process GO:1901566 167 0.030
response to vitamin GO:0033273 131 0.029
response to molecule of bacterial origin GO:0002237 194 0.029
response to ethanol GO:0045471 162 0.029
Rat
single organism behavior GO:0044708 130 0.029
cellular component biogenesis GO:0044085 368 0.029
positive regulation of nucleic acid templated transcription GO:1903508 197 0.029
cellular response to lipid GO:0071396 201 0.029
anion transport GO:0006820 178 0.029
positive regulation of protein phosphorylation GO:0001934 135 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.028
regulation of nervous system development GO:0051960 264 0.028
blood circulation GO:0008015 183 0.028
inorganic ion transmembrane transport GO:0098660 229 0.028
positive regulation of secretion GO:0051047 140 0.028
ion transmembrane transport GO:0034220 365 0.028
regulation of tube size GO:0035150 89 0.028
locomotion GO:0040011 237 0.028
positive regulation of apoptotic process GO:0043065 154 0.028
cellular response to cytokine stimulus GO:0071345 127 0.028
response to growth factor GO:0070848 189 0.028
positive regulation of response to stimulus GO:0048584 285 0.027
response to carbohydrate GO:0009743 183 0.027
response to toxic substance GO:0009636 133 0.027
organic substance catabolic process GO:1901575 316 0.027
cellular chemical homeostasis GO:0055082 247 0.027
organophosphate biosynthetic process GO:0090407 143 0.027
regulation of neurogenesis GO:0050767 247 0.026
metal ion transport GO:0030001 289 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
positive regulation of cell differentiation GO:0045597 217 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.026
cellular response to organonitrogen compound GO:0071417 197 0.026
negative regulation of apoptotic process GO:0043066 181 0.025
response to oxidative stress GO:0006979 186 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
regulation of cell development GO:0060284 263 0.025
regulation of transferase activity GO:0051338 123 0.025
central nervous system development GO:0007417 311 0.025
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
negative regulation of multicellular organismal process GO:0051241 203 0.024
vesicle mediated transport GO:0016192 181 0.024
positive regulation of protein modification process GO:0031401 142 0.024
positive regulation of rna biosynthetic process GO:1902680 197 0.024
proteolysis GO:0006508 175 0.024
negative regulation of cell proliferation GO:0008285 119 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
amide transport GO:0042886 105 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
response to estradiol GO:0032355 164 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.023
cellular ion homeostasis GO:0006873 184 0.023
regulation of blood vessel size GO:0050880 89 0.023
oxidation reduction process GO:0055114 304 0.023
positive regulation of protein metabolic process GO:0051247 178 0.023
developmental process involved in reproduction GO:0003006 159 0.023
negative regulation of rna metabolic process GO:0051253 123 0.023
oligopeptide transport GO:0006857 4 0.023
sexual reproduction GO:0019953 148 0.022
positive regulation of signal transduction GO:0009967 175 0.022
response to inorganic substance GO:0010035 377 0.022
gland development GO:0048732 155 0.022
multicellular organism growth GO:0035264 1 0.022
signal release GO:0023061 145 0.022
response to organophosphorus GO:0046683 102 0.022
response to transition metal nanoparticle GO:1990267 122 0.022
Rat
aging GO:0007568 241 0.022
protein heterooligomerization GO:0051291 89 0.021
ion homeostasis GO:0050801 212 0.021
response to mechanical stimulus GO:0009612 134 0.021
response to oxygen levels GO:0070482 265 0.021
localization of cell GO:0051674 202 0.021
positive regulation of cell communication GO:0010647 271 0.021
circulatory system process GO:0003013 183 0.021
metal ion homeostasis GO:0055065 186 0.021
positive regulation of cell development GO:0010720 176 0.020
response to purine containing compound GO:0014074 126 0.020
response to wounding GO:0009611 254 0.020
negative regulation of protein metabolic process GO:0051248 114 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
signal transduction by phosphorylation GO:0023014 144 0.020
response to estrogen GO:0043627 232 0.020
regulation of neuron death GO:1901214 115 0.020
intracellular transport GO:0046907 185 0.019
regulation of hormone levels GO:0010817 187 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
neuron apoptotic process GO:0051402 88 0.019
hormone transport GO:0009914 121 0.019
cellular cation homeostasis GO:0030003 180 0.019
small molecule biosynthetic process GO:0044283 124 0.019
cellular component movement GO:0006928 248 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
amino acid transport GO:0006865 70 0.019
positive regulation of cell proliferation GO:0008284 249 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
head development GO:0060322 247 0.018
phospholipid metabolic process GO:0006644 61 0.018
gastrulation GO:0007369 2 0.018
rhythmic process GO:0048511 156 0.018
regulation of protein localization GO:0032880 81 0.018
immune response GO:0006955 104 0.018
neuron differentiation GO:0030182 368 0.018
regulation of immune system process GO:0002682 123 0.018
cognition GO:0050890 92 0.018
cellular response to peptide GO:1901653 133 0.018
regulation of neuron differentiation GO:0045664 208 0.018
negative regulation of molecular function GO:0044092 133 0.018
organic anion transport GO:0015711 132 0.018
nucleotide metabolic process GO:0009117 279 0.018
peptide transport GO:0015833 97 0.018
cell type specific apoptotic process GO:0097285 134 0.018
positive regulation of secretion by cell GO:1903532 128 0.017
positive regulation of hormone secretion GO:0046887 65 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
cellular response to peptide hormone stimulus GO:0071375 120 0.017
glycerolipid metabolic process GO:0046486 67 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
anterior posterior pattern specification GO:0009952 1 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
regulation of system process GO:0044057 208 0.017
regulation of mapk cascade GO:0043408 116 0.017
regulation of protein kinase activity GO:0045859 105 0.017
negative regulation of rna biosynthetic process GO:1902679 118 0.017
purine containing compound metabolic process GO:0072521 253 0.017
dephosphorylation GO:0016311 98 0.017
regulation of locomotion GO:0040012 148 0.017
heart morphogenesis GO:0003007 3 0.017
divalent metal ion transport GO:0070838 132 0.017
establishment of protein localization GO:0045184 141 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
response to radiation GO:0009314 137 0.016
response to ketone GO:1901654 182 0.016
female pregnancy GO:0007565 122 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
positive regulation of intracellular signal transduction GO:1902533 138 0.016
positive regulation of locomotion GO:0040017 102 0.016
protein homooligomerization GO:0051260 91 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
organic acid biosynthetic process GO:0016053 83 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
cell activation GO:0001775 97 0.015
axis specification GO:0009798 4 0.015
regulation of kinase activity GO:0043549 117 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
cholesterol homeostasis GO:0042632 3 0.015
reproductive system development GO:0061458 128 0.015
regulation of peptide transport GO:0090087 87 0.015
single organism intracellular transport GO:1902582 166 0.015
organelle organization GO:0006996 266 0.015
positive regulation of response to external stimulus GO:0032103 51 0.015
cellular response to external stimulus GO:0071496 118 0.015
regulation of cell motility GO:2000145 131 0.015
regulation of cellular component movement GO:0051270 150 0.015
sterol homeostasis GO:0055092 3 0.014
carboxylic acid transport GO:0046942 115 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
positive regulation of transferase activity GO:0051347 81 0.014
brain development GO:0007420 247 0.014
cellular amide metabolic process GO:0043603 44 0.014
cell projection organization GO:0030030 302 0.014
response to corticosteroid GO:0031960 235 0.014
b cell differentiation GO:0030183 2 0.014
negative regulation of developmental process GO:0051093 125 0.014
positive regulation of ion transport GO:0043270 94 0.014
heart development GO:0007507 72 0.014
cellular macromolecule localization GO:0070727 122 0.014
endocytosis GO:0006897 84 0.014
sensory organ development GO:0007423 74 0.014
regulation of hydrolase activity GO:0051336 143 0.014
regulation of fat cell differentiation GO:0045598 3 0.014
carboxylic acid biosynthetic process GO:0046394 83 0.014
calcium ion transport GO:0006816 131 0.014
cell motility GO:0048870 202 0.014
neuron development GO:0048666 286 0.014
organic acid transport GO:0015849 116 0.014
cardiovascular system development GO:0072358 134 0.014
circulatory system development GO:0072359 134 0.014
anion transmembrane transport GO:0098656 77 0.014
cellular response to organic cyclic compound GO:0071407 202 0.013
reproductive structure development GO:0048608 128 0.013
response to camp GO:0051591 91 0.013
lipid transport GO:0006869 61 0.013
alpha amino acid catabolic process GO:1901606 20 0.013
muscle system process GO:0003012 115 0.013
cell migration GO:0016477 197 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
insulin like growth factor receptor signaling pathway GO:0048009 3 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
cellular modified amino acid metabolic process GO:0006575 61 0.013
behavior GO:0007610 205 0.013
regulation of cell migration GO:0030334 128 0.013
growth GO:0040007 165 0.013
divalent inorganic cation transport GO:0072511 134 0.013
positive regulation of hydrolase activity GO:0051345 86 0.013
response to glucocorticoid GO:0051384 223 0.013
chromosome segregation GO:0007059 2 0.013
regulation of anatomical structure size GO:0090066 135 0.013
monocarboxylic acid transport GO:0015718 52 0.013
embryonic pattern specification GO:0009880 1 0.012
response to monosaccharide GO:0034284 159 0.012
gamete generation GO:0007276 124 0.012
negative regulation of transport GO:0051051 136 0.012
response to glucose GO:0009749 136 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
protein localization GO:0008104 191 0.012
regulation of metal ion transport GO:0010959 118 0.012
neuron projection development GO:0031175 273 0.012
synaptic transmission GO:0007268 235 0.012
intracellular receptor signaling pathway GO:0030522 35 0.012
lipid localization GO:0010876 62 0.012
lipid storage GO:0019915 1 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
regulation of neuron apoptotic process GO:0043523 83 0.012
calcium ion homeostasis GO:0055074 162 0.012
regulation of lipid metabolic process GO:0019216 68 0.012
regulation of growth GO:0040008 105 0.012
insulin receptor signaling pathway GO:0008286 24 0.012
ribose phosphate metabolic process GO:0019693 235 0.011
regulation of response to stress GO:0080134 126 0.011
response to fatty acid GO:0070542 65 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
peptidyl amino acid modification GO:0018193 126 0.011
ras protein signal transduction GO:0007265 29 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
alcohol metabolic process GO:0006066 77 0.011
biological adhesion GO:0022610 110 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
regulation of body fluid levels GO:0050878 90 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.011
tube development GO:0035295 89 0.011
mesoderm development GO:0007498 2 0.011
regulation of catabolic process GO:0009894 113 0.010
salivary gland development GO:0007431 3 0.010
maintenance of location GO:0051235 17 0.010
insulin secretion GO:0030073 69 0.010
response to alkaloid GO:0043279 132 0.010
dna metabolic process GO:0006259 96 0.010
protein maturation GO:0051604 68 0.010
positive regulation of immune system process GO:0002684 90 0.010
cellular biogenic amine metabolic process GO:0006576 30 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
positive regulation of cytokine production GO:0001819 42 0.010
cytoplasmic transport GO:0016482 115 0.010
regulation of peptide secretion GO:0002791 82 0.010
negative regulation of collagen biosynthetic process GO:0032966 4 0.010
cellular protein localization GO:0034613 122 0.010
cellular response to starvation GO:0009267 27 0.010
cell growth GO:0016049 104 0.010
positive regulation of cell motility GO:2000147 97 0.010

Sts disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.020
musculoskeletal system disease DOID:17 0 0.017
central nervous system disease DOID:331 0 0.015
sensory system disease DOID:0050155 0 0.013
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012
myopathy DOID:423 0 0.010