Rattus norvegicus

0 known processes

R3hdm2

R3H domain containing 2

(Aliases: RGD1310066)

R3hdm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
programmed cell death GO:0012501 392 0.066
cellular component assembly GO:0022607 360 0.063
transcription from rna polymerase ii promoter GO:0006366 252 0.059
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.055
regulation of rna biosynthetic process GO:2001141 381 0.053
rna biosynthetic process GO:0032774 380 0.052
anterior posterior pattern specification GO:0009952 1 0.048
nucleic acid templated transcription GO:0097659 379 0.048
oxoacid metabolic process GO:0043436 290 0.048
reproductive process GO:0022414 372 0.047
regulation of cell development GO:0060284 263 0.046
protein phosphorylation GO:0006468 345 0.046
organic acid metabolic process GO:0006082 292 0.044
positive regulation of multicellular organismal process GO:0051240 387 0.042
intracellular signal transduction GO:0035556 314 0.041
anatomical structure morphogenesis GO:0009653 298 0.041
regulation of nucleic acid templated transcription GO:1903506 380 0.041
cellular component biogenesis GO:0044085 368 0.041
rna metabolic process GO:0016070 406 0.040
neuron differentiation GO:0030182 368 0.039
cellular amine metabolic process GO:0044106 38 0.038
positive regulation of cell communication GO:0010647 271 0.038
cell projection organization GO:0030030 302 0.037
regulation of cell differentiation GO:0045595 320 0.037
carboxylic acid metabolic process GO:0019752 289 0.037
regulation of neurogenesis GO:0050767 247 0.036
regulation of rna metabolic process GO:0051252 391 0.036
regulation of phosphorus metabolic process GO:0051174 349 0.036
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.035
regulation of nervous system development GO:0051960 264 0.035
response to inorganic substance GO:0010035 377 0.035
single organism intracellular transport GO:1902582 166 0.035
cellular response to oxygen containing compound GO:1901701 386 0.035
regulation of signal transduction GO:0009966 318 0.035
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.033
cell cell signaling GO:0007267 335 0.033
regulation of catalytic activity GO:0050790 304 0.033
protein localization GO:0008104 191 0.033
positive regulation of rna metabolic process GO:0051254 203 0.032
neuron development GO:0048666 286 0.032
neuron projection development GO:0031175 273 0.032
catabolic process GO:0009056 351 0.032
apoptotic process GO:0006915 381 0.032
single organism reproductive process GO:0044702 297 0.031
regulation of transcription dna templated GO:0006355 374 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.031
cellular macromolecule localization GO:0070727 122 0.031
cellular component morphogenesis GO:0032989 155 0.031
cell morphogenesis GO:0000902 142 0.031
positive regulation of gene expression GO:0010628 244 0.030
regulation of molecular function GO:0065009 398 0.030
positive regulation of cell proliferation GO:0008284 249 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
cellular ketone metabolic process GO:0042180 51 0.029
regulation of cellular localization GO:0060341 263 0.029
cellular amino acid metabolic process GO:0006520 107 0.029
secretion GO:0046903 307 0.029
protein complex subunit organization GO:0071822 302 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
positive regulation of nervous system development GO:0051962 178 0.029
regulation of programmed cell death GO:0043067 341 0.028
homeostatic process GO:0042592 331 0.028
cellular protein localization GO:0034613 122 0.027
transcription dna templated GO:0006351 377 0.027
positive regulation of rna biosynthetic process GO:1902680 197 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
positive regulation of nucleic acid templated transcription GO:1903508 197 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
organic substance catabolic process GO:1901575 316 0.026
positive regulation of neurogenesis GO:0050769 165 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
negative regulation of signaling GO:0023057 157 0.026
response to carbohydrate GO:0009743 183 0.026
response to metal ion GO:0010038 253 0.026
negative regulation of cell communication GO:0010648 158 0.025
regulation of cellular component organization GO:0051128 368 0.025
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
regulation of protein metabolic process GO:0051246 289 0.024
intracellular transport GO:0046907 185 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
cellular response to hormone stimulus GO:0032870 247 0.024
cell projection morphogenesis GO:0048858 123 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.023
negative regulation of nervous system development GO:0051961 79 0.023
cellular catabolic process GO:0044248 295 0.023
organelle organization GO:0006996 266 0.023
macromolecule localization GO:0033036 252 0.023
organophosphate metabolic process GO:0019637 370 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
positive regulation of cell development GO:0010720 176 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
multi organism reproductive process GO:0044703 262 0.022
signal transduction by phosphorylation GO:0023014 144 0.022
positive regulation of developmental process GO:0051094 283 0.022
positive regulation of transport GO:0051050 245 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
mesoderm development GO:0007498 2 0.022
amine metabolic process GO:0009308 38 0.022
regulation of neuron differentiation GO:0045664 208 0.022
tissue development GO:0009888 252 0.022
cellular response to stress GO:0033554 269 0.021
central nervous system development GO:0007417 311 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
regulation of transferase activity GO:0051338 123 0.021
macromolecular complex assembly GO:0065003 273 0.021
positive regulation of protein modification process GO:0031401 142 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
embryonic pattern specification GO:0009880 1 0.021
head development GO:0060322 247 0.021
positive regulation of molecular function GO:0044093 230 0.021
multicellular organismal reproductive process GO:0048609 233 0.020
protein complex assembly GO:0006461 263 0.020
negative regulation of cell differentiation GO:0045596 99 0.020
protein oligomerization GO:0051259 191 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
regulation of neuron projection development GO:0010975 161 0.020
response to cytokine GO:0034097 215 0.020
negative regulation of metabolic process GO:0009892 331 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
heart morphogenesis GO:0003007 3 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.020
regulation of cell projection organization GO:0031344 175 0.019
tube development GO:0035295 89 0.019
response to nutrient levels GO:0031667 370 0.019
negative regulation of developmental process GO:0051093 125 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
single organism catabolic process GO:0044712 283 0.019
secretion by cell GO:0032940 248 0.019
developmental process involved in reproduction GO:0003006 159 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
regulation of protein modification process GO:0031399 194 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
gastrulation GO:0007369 2 0.018
regulation of apoptotic process GO:0042981 335 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
cell morphogenesis involved in differentiation GO:0000904 119 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
regulation of cell proliferation GO:0042127 359 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
cell growth GO:0016049 104 0.018
reproduction GO:0000003 245 0.018
negative regulation of neurogenesis GO:0050768 78 0.018
response to glucose GO:0009749 136 0.018
aging GO:0007568 241 0.018
response to extracellular stimulus GO:0009991 380 0.017
response to oxygen levels GO:0070482 265 0.017
rhythmic process GO:0048511 156 0.017
neuron projection morphogenesis GO:0048812 122 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
axis specification GO:0009798 4 0.017
growth GO:0040007 165 0.017
nucleotide metabolic process GO:0009117 279 0.017
response to peptide GO:1901652 292 0.017
axonogenesis GO:0007409 71 0.017
signal release GO:0023061 145 0.017
multicellular organism reproduction GO:0032504 233 0.017
establishment of protein localization GO:0045184 141 0.017
regulation of catabolic process GO:0009894 113 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
positive regulation of response to stimulus GO:0048584 285 0.016
regulation of phosphorylation GO:0042325 248 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
purine containing compound metabolic process GO:0072521 253 0.016
single organism biosynthetic process GO:0044711 342 0.016
response to corticosteroid GO:0031960 235 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.016
mapk cascade GO:0000165 140 0.016
response to oxidative stress GO:0006979 186 0.016
locomotion GO:0040011 237 0.016
negative regulation of cell development GO:0010721 82 0.016
multi multicellular organism process GO:0044706 138 0.016
cellular homeostasis GO:0019725 252 0.016
single organism behavior GO:0044708 130 0.016
response to decreased oxygen levels GO:0036293 237 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
gamete generation GO:0007276 124 0.016
positive regulation of secretion GO:0051047 140 0.016
positive regulation of neuron projection development GO:0010976 99 0.015
response to hexose GO:0009746 144 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
behavior GO:0007610 205 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
regulation of system process GO:0044057 208 0.015
regulation of protein kinase activity GO:0045859 105 0.015
cytoplasmic transport GO:0016482 115 0.015
sexual reproduction GO:0019953 148 0.015
circulatory system development GO:0072359 134 0.015
single organism cellular localization GO:1902580 102 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
negative regulation of gene expression GO:0010629 199 0.015
embryonic axis specification GO:0000578 1 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
single organism organelle organization GO:1902589 180 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
regulation of secretion GO:0051046 224 0.014
olfactory learning GO:0008355 1 0.014
cellular response to lipid GO:0071396 201 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
nitrogen compound transport GO:0071705 229 0.014
multicellular organism growth GO:0035264 1 0.014
positive regulation of signal transduction GO:0009967 175 0.014
epithelium development GO:0060429 96 0.014
ras protein signal transduction GO:0007265 29 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
protein homooligomerization GO:0051260 91 0.014
mitotic spindle organization GO:0007052 2 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
regulation of hydrolase activity GO:0051336 143 0.014
negative regulation of cell death GO:0060548 229 0.013
cell part morphogenesis GO:0032990 123 0.013
regulation of mapk cascade GO:0043408 116 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
cellular chemical homeostasis GO:0055082 247 0.013
nucleoside metabolic process GO:0009116 179 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
intracellular protein transport GO:0006886 79 0.013
hormone secretion GO:0046879 115 0.013
chemosensory behavior GO:0007635 2 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
response to hypoxia GO:0001666 231 0.013
response to monosaccharide GO:0034284 159 0.013
regulation of growth GO:0040008 105 0.013
response to growth factor GO:0070848 189 0.013
brain development GO:0007420 247 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
cation transport GO:0006812 382 0.013
reproductive structure development GO:0048608 128 0.013
regulation of secretion by cell GO:1903530 208 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
transmembrane transport GO:0055085 412 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
synaptic transmission GO:0007268 235 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
neurological system process GO:0050877 219 0.013
regulation of cell growth GO:0001558 85 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
protein transport GO:0015031 132 0.012
peptidyl amino acid modification GO:0018193 126 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
positive regulation of ion transport GO:0043270 94 0.012
rna localization GO:0006403 4 0.012
response to biotic stimulus GO:0009607 226 0.012
protein autophosphorylation GO:0046777 66 0.012
cardiovascular system development GO:0072358 134 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
chemical homeostasis GO:0048878 292 0.012
protein targeting GO:0006605 61 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
membrane organization GO:0061024 94 0.012
response to wounding GO:0009611 254 0.012
anion transport GO:0006820 178 0.012
response to acid chemical GO:0001101 222 0.012
neuron death GO:0070997 127 0.012
amide transport GO:0042886 105 0.011
tube formation GO:0035148 3 0.011
sex differentiation GO:0007548 113 0.011
regulation of hormone levels GO:0010817 187 0.011
regulation of neuron death GO:1901214 115 0.011
organic acid transport GO:0015849 116 0.011
response to bacterium GO:0009617 200 0.011
bmp signaling pathway GO:0030509 4 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
chromosome segregation GO:0007059 2 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
regulation of synaptic transmission GO:0050804 141 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
muscle system process GO:0003012 115 0.011
regulation of kinase activity GO:0043549 117 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
nucleotide catabolic process GO:0009166 139 0.011
heterocycle catabolic process GO:0046700 167 0.011
response to estrogen GO:0043627 232 0.011
positive regulation of signaling GO:0023056 270 0.011
heart development GO:0007507 72 0.011
cellular response to carbohydrate stimulus GO:0071322 72 0.011
regulation of cell migration GO:0030334 128 0.011
salivary gland morphogenesis GO:0007435 1 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
negative regulation of molecular function GO:0044092 133 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
regulation of dendrite development GO:0050773 59 0.011
glucose homeostasis GO:0042593 75 0.011
peptide secretion GO:0002790 86 0.011
gonad development GO:0008406 104 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
response to mechanical stimulus GO:0009612 134 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
regulation of cellular catabolic process GO:0031329 101 0.010
regulation of stem cell differentiation GO:2000736 2 0.010
cardiac chamber development GO:0003205 1 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
regulation of membrane potential GO:0042391 110 0.010
organophosphate catabolic process GO:0046434 148 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
urogenital system development GO:0001655 78 0.010
negative regulation of cell proliferation GO:0008285 119 0.010
proteolysis GO:0006508 175 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
forebrain development GO:0030900 98 0.010
response to external biotic stimulus GO:0043207 221 0.010
motor neuron axon guidance GO:0008045 1 0.010
regulation of peptide secretion GO:0002791 82 0.010
multicellular organismal signaling GO:0035637 44 0.010
positive regulation of transferase activity GO:0051347 81 0.010
jnk cascade GO:0007254 28 0.010
nucleocytoplasmic transport GO:0006913 48 0.010
cell type specific apoptotic process GO:0097285 134 0.010
regulation of protein localization GO:0032880 81 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
embryo development GO:0009790 49 0.010
regulation of response to stress GO:0080134 126 0.010
cellular response to nitrogen compound GO:1901699 210 0.010
negative regulation of signal transduction GO:0009968 83 0.010

R3hdm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
central nervous system disease DOID:331 0 0.014
musculoskeletal system disease DOID:17 0 0.012
disease of metabolism DOID:0014667 0 0.011
disease of cellular proliferation DOID:14566 0 0.011