Rattus norvegicus

0 known processes

Trove2

TROVE domain family, member 2

(Aliases: Ssa2)

Trove2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
programmed cell death GO:0012501 392 0.069
negative regulation of metabolic process GO:0009892 331 0.051
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.049
apoptotic process GO:0006915 381 0.045
catabolic process GO:0009056 351 0.044
organic acid metabolic process GO:0006082 292 0.044
regulation of cellular component organization GO:0051128 368 0.044
protein phosphorylation GO:0006468 345 0.043
response to nutrient levels GO:0031667 370 0.043
organic substance catabolic process GO:1901575 316 0.041
macromolecular complex subunit organization GO:0043933 339 0.040
regulation of apoptotic process GO:0042981 335 0.040
regulation of rna metabolic process GO:0051252 391 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.038
synaptic transmission GO:0007268 235 0.037
oxoacid metabolic process GO:0043436 290 0.037
cellular catabolic process GO:0044248 295 0.035
rhythmic process GO:0048511 156 0.035
regulation of cellular protein metabolic process GO:0032268 267 0.034
regulation of rna biosynthetic process GO:2001141 381 0.034
transcription dna templated GO:0006351 377 0.034
regulation of nucleic acid templated transcription GO:1903506 380 0.031
negative regulation of programmed cell death GO:0043069 183 0.031
cellular component biogenesis GO:0044085 368 0.031
neural crest cell differentiation GO:0014033 2 0.031
response to metal ion GO:0010038 253 0.030
response to extracellular stimulus GO:0009991 380 0.030
regulation of phosphate metabolic process GO:0019220 349 0.029
regulation of programmed cell death GO:0043067 341 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
cellular protein localization GO:0034613 122 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
heart morphogenesis GO:0003007 3 0.027
multicellular organismal reproductive process GO:0048609 233 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
macromolecule localization GO:0033036 252 0.026
axis specification GO:0009798 4 0.026
cellular macromolecule localization GO:0070727 122 0.026
regulation of protein metabolic process GO:0051246 289 0.026
negative regulation of apoptotic process GO:0043066 181 0.026
single organism reproductive process GO:0044702 297 0.025
protein localization GO:0008104 191 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.025
nucleic acid templated transcription GO:0097659 379 0.025
cell type specific apoptotic process GO:0097285 134 0.025
cell cell signaling GO:0007267 335 0.025
macromolecular complex assembly GO:0065003 273 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
cellular component assembly GO:0022607 360 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
cellular response to stress GO:0033554 269 0.024
negative regulation of gene expression GO:0010629 199 0.024
synaptic growth at neuromuscular junction GO:0051124 1 0.024
positive regulation of transcription dna templated GO:0045893 197 0.024
multicellular organism reproduction GO:0032504 233 0.024
cellular ketone metabolic process GO:0042180 51 0.023
organelle organization GO:0006996 266 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
reproduction GO:0000003 245 0.023
rna metabolic process GO:0016070 406 0.023
regulation of protein modification process GO:0031399 194 0.023
cellular amine metabolic process GO:0044106 38 0.023
single organism catabolic process GO:0044712 283 0.023
regulation of signal transduction GO:0009966 318 0.022
regulation of cellular localization GO:0060341 263 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
response to cytokine GO:0034097 215 0.022
neuron projection development GO:0031175 273 0.022
multi organism reproductive process GO:0044703 262 0.022
carboxylic acid metabolic process GO:0019752 289 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
reproductive process GO:0022414 372 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
amine metabolic process GO:0009308 38 0.021
intracellular transport GO:0046907 185 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
transmembrane transport GO:0055085 412 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.020
cell projection organization GO:0030030 302 0.020
cation transport GO:0006812 382 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
male mating behavior GO:0060179 3 0.020
circadian rhythm GO:0007623 88 0.020
rna biosynthetic process GO:0032774 380 0.020
protein transport GO:0015031 132 0.019
cell cycle checkpoint GO:0000075 2 0.019
response to decreased oxygen levels GO:0036293 237 0.019
cellular response to oxygen containing compound GO:1901701 386 0.019
intracellular protein transport GO:0006886 79 0.019
regulation of phosphorylation GO:0042325 248 0.019
positive regulation of transport GO:0051050 245 0.019
intracellular signal transduction GO:0035556 314 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
gland development GO:0048732 155 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
brain development GO:0007420 247 0.019
response to nutrient GO:0007584 248 0.018
sexual reproduction GO:0019953 148 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
protein modification by small protein conjugation or removal GO:0070647 35 0.018
positive regulation of cell communication GO:0010647 271 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
negative regulation of cell death GO:0060548 229 0.018
regulation of neurogenesis GO:0050767 247 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
homeostatic process GO:0042592 331 0.018
regulation of catalytic activity GO:0050790 304 0.018
neuron differentiation GO:0030182 368 0.017
regulation of transcription dna templated GO:0006355 374 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
ras protein signal transduction GO:0007265 29 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
cellular component movement GO:0006928 248 0.017
regulation of nervous system development GO:0051960 264 0.017
single organism organelle organization GO:1902589 180 0.017
ion transmembrane transport GO:0034220 365 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
multi multicellular organism process GO:0044706 138 0.017
gamete generation GO:0007276 124 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
establishment of protein localization GO:0045184 141 0.016
response to inorganic substance GO:0010035 377 0.016
positive regulation of gene expression GO:0010628 244 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
positive regulation of signal transduction GO:0009967 175 0.016
single organism biosynthetic process GO:0044711 342 0.016
negative regulation of molecular function GO:0044092 133 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
organophosphate metabolic process GO:0019637 370 0.016
positive regulation of signaling GO:0023056 270 0.016
regulation of cell development GO:0060284 263 0.016
positive regulation of molecular function GO:0044093 230 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
regulation of canonical wnt signaling pathway GO:0060828 4 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
negative regulation of protein metabolic process GO:0051248 114 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
nucleotide metabolic process GO:0009117 279 0.015
anatomical structure morphogenesis GO:0009653 298 0.015
eye morphogenesis GO:0048592 4 0.015
response to external biotic stimulus GO:0043207 221 0.015
response to purine containing compound GO:0014074 126 0.015
neuromuscular synaptic transmission GO:0007274 2 0.015
cytoplasmic transport GO:0016482 115 0.015
nucleoside metabolic process GO:0009116 179 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
response to peptide GO:1901652 292 0.015
neuron death GO:0070997 127 0.015
protein complex biogenesis GO:0070271 263 0.015
response to growth factor GO:0070848 189 0.014
protein oligomerization GO:0051259 191 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
chemical homeostasis GO:0048878 292 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
regulation of neuron death GO:1901214 115 0.014
regulation of cell proliferation GO:0042127 359 0.014
response to radiation GO:0009314 137 0.014
response to acid chemical GO:0001101 222 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
neurological system process GO:0050877 219 0.014
aging GO:0007568 241 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
positive regulation of catabolic process GO:0009896 78 0.014
neuron development GO:0048666 286 0.014
anterior posterior pattern specification GO:0009952 1 0.014
cellular homeostasis GO:0019725 252 0.014
central nervous system development GO:0007417 311 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
protein complex subunit organization GO:0071822 302 0.014
response to ethanol GO:0045471 162 0.013
regulation of secretion GO:0051046 224 0.013
regulation of cell differentiation GO:0045595 320 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
response to hypoxia GO:0001666 231 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
embryonic pattern specification GO:0009880 1 0.013
single organism intracellular transport GO:1902582 166 0.013
neuronal action potential GO:0019228 35 0.013
regulation of hydrolase activity GO:0051336 143 0.012
hair cycle process GO:0022405 2 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
purine containing compound metabolic process GO:0072521 253 0.012
negative regulation of neuron death GO:1901215 69 0.012
nucleotide catabolic process GO:0009166 139 0.012
heterocycle catabolic process GO:0046700 167 0.012
head development GO:0060322 247 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
organophosphate catabolic process GO:0046434 148 0.012
cation transmembrane transport GO:0098655 263 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
anion transport GO:0006820 178 0.012
nitrogen compound transport GO:0071705 229 0.012
lipid metabolic process GO:0006629 283 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
secretion GO:0046903 307 0.012
protein complex assembly GO:0006461 263 0.012
neuron projection morphogenesis GO:0048812 122 0.012
appendage morphogenesis GO:0035107 4 0.012
response to ketone GO:1901654 182 0.012
response to hexose GO:0009746 144 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
cell part morphogenesis GO:0032990 123 0.012
purine containing compound catabolic process GO:0072523 138 0.012
regulation of membrane potential GO:0042391 110 0.012
macromolecule catabolic process GO:0009057 58 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
single organism membrane organization GO:0044802 74 0.011
regulation of cell cycle GO:0051726 73 0.011
positive regulation of developmental process GO:0051094 283 0.011
molting cycle process GO:0022404 2 0.011
regulation of secretion by cell GO:1903530 208 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
cell migration GO:0016477 197 0.011
negative regulation of nervous system development GO:0051961 79 0.011
cellular component morphogenesis GO:0032989 155 0.011
action potential GO:0001508 54 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
response to carbohydrate GO:0009743 183 0.011
response to mechanical stimulus GO:0009612 134 0.011
cell motility GO:0048870 202 0.011
regulation of molecular function GO:0065009 398 0.011
response to peptide hormone GO:0043434 278 0.011
regulation of transferase activity GO:0051338 123 0.011
female pregnancy GO:0007565 122 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
maintenance of location GO:0051235 17 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
positive regulation of protein modification process GO:0031401 142 0.011
regulation of neuron differentiation GO:0045664 208 0.011
muscle cell proliferation GO:0033002 84 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
lipid storage GO:0019915 1 0.011
regulation of catabolic process GO:0009894 113 0.011
cell projection morphogenesis GO:0048858 123 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
regulation of anatomical structure size GO:0090066 135 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
cellular response to endogenous stimulus GO:0071495 377 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
protein modification by small protein conjugation GO:0032446 31 0.010
response to corticosteroid GO:0031960 235 0.010
response to oxygen levels GO:0070482 265 0.010
lipid biosynthetic process GO:0008610 128 0.010
proteolysis GO:0006508 175 0.010
cellular response to lipid GO:0071396 201 0.010
cytoskeleton organization GO:0007010 111 0.010
regulation of growth GO:0040008 105 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
response to organophosphorus GO:0046683 102 0.010
organonitrogen compound biosynthetic process GO:1901566 167 0.010
cellular chemical homeostasis GO:0055082 247 0.010
protein heterooligomerization GO:0051291 89 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
non canonical wnt signaling pathway GO:0035567 3 0.010
aromatic compound catabolic process GO:0019439 168 0.010
rna localization GO:0006403 4 0.010
neural crest cell development GO:0014032 2 0.010

Trove2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.028
disease of anatomical entity DOID:7 0 0.028
central nervous system disease DOID:331 0 0.012
eye disease DOID:5614 0 0.011
eye and adnexa disease DOID:1492 0 0.011
sensory system disease DOID:0050155 0 0.011