Rattus norvegicus

0 known processes

Ercc8

excision repair cross-complementing rodent repair deficiency, complementation group 8

(Aliases: Ckn1)

Ercc8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell cell signaling GO:0007267 335 0.096
anatomical structure morphogenesis GO:0009653 298 0.063
transcription dna templated GO:0006351 377 0.062
oxoacid metabolic process GO:0043436 290 0.061
cellular component movement GO:0006928 248 0.060
regulation of transcription dna templated GO:0006355 374 0.060
reproductive process GO:0022414 372 0.058
organic acid metabolic process GO:0006082 292 0.057
rna metabolic process GO:0016070 406 0.057
carboxylic acid metabolic process GO:0019752 289 0.054
rna biosynthetic process GO:0032774 380 0.054
regulation of nucleic acid templated transcription GO:1903506 380 0.045
cation transport GO:0006812 382 0.045
reproduction GO:0000003 245 0.043
organelle organization GO:0006996 266 0.039
neuron differentiation GO:0030182 368 0.039
secretion GO:0046903 307 0.039
programmed cell death GO:0012501 392 0.039
response to oxygen levels GO:0070482 265 0.039
sexual reproduction GO:0019953 148 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
neurological system process GO:0050877 219 0.038
synaptic growth at neuromuscular junction GO:0051124 1 0.037
locomotion GO:0040011 237 0.036
regulation of rna metabolic process GO:0051252 391 0.036
nucleic acid templated transcription GO:0097659 379 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.033
regulation of apoptotic process GO:0042981 335 0.033
response to inorganic substance GO:0010035 377 0.033
brain development GO:0007420 247 0.033
central nervous system development GO:0007417 311 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
regulation of rna biosynthetic process GO:2001141 381 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.033
negative regulation of metabolic process GO:0009892 331 0.033
apoptotic process GO:0006915 381 0.032
protein complex subunit organization GO:0071822 302 0.032
regulation of cell differentiation GO:0045595 320 0.032
cellular component assembly GO:0022607 360 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.032
homeostatic process GO:0042592 331 0.031
negative regulation of gene expression GO:0010629 199 0.030
multicellular organism reproduction GO:0032504 233 0.030
cellular response to stress GO:0033554 269 0.030
positive regulation of developmental process GO:0051094 283 0.029
chemical homeostasis GO:0048878 292 0.029
response to metal ion GO:0010038 253 0.029
positive regulation of cellular component organization GO:0051130 200 0.029
positive regulation of biosynthetic process GO:0009891 319 0.029
positive regulation of phosphate metabolic process GO:0045937 262 0.029
cellular chemical homeostasis GO:0055082 247 0.028
cellular amine metabolic process GO:0044106 38 0.028
response to nutrient levels GO:0031667 370 0.028
multi organism reproductive process GO:0044703 262 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
cellular homeostasis GO:0019725 252 0.027
ion homeostasis GO:0050801 212 0.027
single organism reproductive process GO:0044702 297 0.027
inorganic ion transmembrane transport GO:0098660 229 0.027
response to extracellular stimulus GO:0009991 380 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
ribose phosphate metabolic process GO:0019693 235 0.026
regulation of cell migration GO:0030334 128 0.026
response to peptide GO:1901652 292 0.026
cell projection organization GO:0030030 302 0.026
positive regulation of gene expression GO:0010628 244 0.026
positive regulation of cell death GO:0010942 184 0.026
behavior GO:0007610 205 0.026
regulation of programmed cell death GO:0043067 341 0.026
intracellular signal transduction GO:0035556 314 0.025
response to decreased oxygen levels GO:0036293 237 0.025
regulation of nervous system development GO:0051960 264 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
nucleotide metabolic process GO:0009117 279 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.025
regulation of cellular component organization GO:0051128 368 0.025
nitrogen compound transport GO:0071705 229 0.025
negative regulation of rna metabolic process GO:0051253 123 0.025
cellular response to oxygen containing compound GO:1901701 386 0.025
amine metabolic process GO:0009308 38 0.025
regulation of phosphate metabolic process GO:0019220 349 0.025
multicellular organismal reproductive process GO:0048609 233 0.024
macromolecular complex assembly GO:0065003 273 0.024
protein oligomerization GO:0051259 191 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.023
single organism organelle organization GO:1902589 180 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
synaptic transmission GO:0007268 235 0.023
cytoskeleton organization GO:0007010 111 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
localization of cell GO:0051674 202 0.023
metal ion transport GO:0030001 289 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.022
aging GO:0007568 241 0.022
transmembrane transport GO:0055085 412 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
cellular component biogenesis GO:0044085 368 0.022
protein complex biogenesis GO:0070271 263 0.022
regulation of neuron projection development GO:0010975 161 0.021
regulation of neuron differentiation GO:0045664 208 0.021
response to cytokine GO:0034097 215 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
organic substance catabolic process GO:1901575 316 0.021
negative regulation of cell communication GO:0010648 158 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
macromolecule localization GO:0033036 252 0.021
gamete generation GO:0007276 124 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
regulation of neurogenesis GO:0050767 247 0.021
organophosphate metabolic process GO:0019637 370 0.021
response to hypoxia GO:0001666 231 0.020
g protein coupled receptor signaling pathway GO:0007186 242 0.020
neuron projection development GO:0031175 273 0.020
regulation of anatomical structure size GO:0090066 135 0.020
neuron development GO:0048666 286 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
protein localization GO:0008104 191 0.020
regulation of cell development GO:0060284 263 0.020
regulation of cellular component movement GO:0051270 150 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
cellular lipid metabolic process GO:0044255 208 0.019
anion transport GO:0006820 178 0.019
single organism biosynthetic process GO:0044711 342 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
cell motility GO:0048870 202 0.019
cation transmembrane transport GO:0098655 263 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
organonitrogen compound biosynthetic process GO:1901566 167 0.019
vesicle mediated transport GO:0016192 181 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
protein phosphorylation GO:0006468 345 0.019
tissue development GO:0009888 252 0.019
regulation of synaptic transmission GO:0050804 141 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.018
hormone transport GO:0009914 121 0.018
negative regulation of cell death GO:0060548 229 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
positive regulation of cell communication GO:0010647 271 0.018
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
response to acid chemical GO:0001101 222 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
regulation of protein metabolic process GO:0051246 289 0.018
cellular ketone metabolic process GO:0042180 51 0.018
defense response GO:0006952 194 0.018
negative regulation of signaling GO:0023057 157 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
regulation of dendrite development GO:0050773 59 0.018
organic anion transport GO:0015711 132 0.018
spindle organization GO:0007051 2 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
cellular ion homeostasis GO:0006873 184 0.018
anterior posterior pattern specification GO:0009952 1 0.018
purine containing compound metabolic process GO:0072521 253 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
regulation of secretion GO:0051046 224 0.017
lipid metabolic process GO:0006629 283 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
single organism cellular localization GO:1902580 102 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
response to growth factor GO:0070848 189 0.017
hormone secretion GO:0046879 115 0.017
nucleoside metabolic process GO:0009116 179 0.017
protein complex assembly GO:0006461 263 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
cell migration GO:0016477 197 0.017
head development GO:0060322 247 0.017
fatty acid metabolic process GO:0006631 99 0.017
negative regulation of rna biosynthetic process GO:1902679 118 0.017
secretion by cell GO:0032940 248 0.016
regulation of signal transduction GO:0009966 318 0.016
response to radiation GO:0009314 137 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
catabolic process GO:0009056 351 0.016
regulation of cell proliferation GO:0042127 359 0.016
regulation of hormone levels GO:0010817 187 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
actin cytoskeleton organization GO:0030036 73 0.016
ras protein signal transduction GO:0007265 29 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
proteolysis GO:0006508 175 0.016
cellular component morphogenesis GO:0032989 155 0.016
eye morphogenesis GO:0048592 4 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
response to corticosteroid GO:0031960 235 0.016
regulation of molecular function GO:0065009 398 0.015
cellular cation homeostasis GO:0030003 180 0.015
regulation of ion transport GO:0043269 245 0.015
regulation of secretion by cell GO:1903530 208 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
growth GO:0040007 165 0.015
axon development GO:0061564 96 0.015
signal release GO:0023061 145 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
positive regulation of molecular function GO:0044093 230 0.015
calcium ion transport GO:0006816 131 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
cation homeostasis GO:0055080 195 0.015
response to glucocorticoid GO:0051384 223 0.015
ion transmembrane transport GO:0034220 365 0.015
regulation of catalytic activity GO:0050790 304 0.015
response to ethanol GO:0045471 162 0.015
embryonic skeletal system development GO:0048706 3 0.015
cellular response to endogenous stimulus GO:0071495 377 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
gastrulation GO:0007369 2 0.014
divalent metal ion transport GO:0070838 132 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
response to glucose GO:0009749 136 0.014
response to peptide hormone GO:0043434 278 0.014
regulation of phosphorylation GO:0042325 248 0.014
peptidyl amino acid modification GO:0018193 126 0.014
mesoderm development GO:0007498 2 0.014
regulation of system process GO:0044057 208 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
response to oxidative stress GO:0006979 186 0.014
organic acid transport GO:0015849 116 0.014
male gamete generation GO:0048232 99 0.014
positive regulation of nervous system development GO:0051962 178 0.014
gliogenesis GO:0042063 93 0.014
lipid biosynthetic process GO:0008610 128 0.014
single organism intracellular transport GO:1902582 166 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
small molecule biosynthetic process GO:0044283 124 0.014
nucleobase containing small molecule metabolic process GO:0055086 316 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
developmental process involved in reproduction GO:0003006 159 0.014
regulation of cell projection organization GO:0031344 175 0.014
response to toxic substance GO:0009636 133 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
positive regulation of response to stimulus GO:0048584 285 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
peptide secretion GO:0002790 86 0.013
cellular catabolic process GO:0044248 295 0.013
response to external biotic stimulus GO:0043207 221 0.013
regulation of membrane potential GO:0042391 110 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
spermatogenesis GO:0007283 99 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
positive regulation of cell development GO:0010720 176 0.013
aromatic compound catabolic process GO:0019439 168 0.013
embryonic pattern specification GO:0009880 1 0.013
response to lipopolysaccharide GO:0032496 191 0.013
positive regulation of signaling GO:0023056 270 0.013
response to monosaccharide GO:0034284 159 0.013
neuron death GO:0070997 127 0.013
negative regulation of developmental process GO:0051093 125 0.013
positive regulation of transport GO:0051050 245 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
organic cyclic compound catabolic process GO:1901361 175 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
amide transport GO:0042886 105 0.012
response to reactive oxygen species GO:0000302 120 0.012
protein homooligomerization GO:0051260 91 0.012
carbohydrate homeostasis GO:0033500 75 0.012
response to carbohydrate GO:0009743 183 0.012
positive regulation of secretion GO:0051047 140 0.012
regulation of neuron death GO:1901214 115 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
regeneration GO:0031099 163 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
immune system process GO:0002376 204 0.012
regulation of hormone secretion GO:0046883 106 0.012
carboxylic acid transport GO:0046942 115 0.012
alpha amino acid metabolic process GO:1901605 71 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
neural crest cell development GO:0014032 2 0.012
neuronal action potential GO:0019228 35 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
negative regulation of cell development GO:0010721 82 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
actin filament based process GO:0030029 86 0.011
peptide transport GO:0015833 97 0.011
cellular protein localization GO:0034613 122 0.011
response to other organism GO:0051707 220 0.011
chromosome segregation GO:0007059 2 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
intracellular transport GO:0046907 185 0.011
epithelium development GO:0060429 96 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
response to ketone GO:1901654 182 0.011
axis specification GO:0009798 4 0.011
sensory perception GO:0007600 101 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
metal ion homeostasis GO:0055065 186 0.011
regulation of locomotion GO:0040012 148 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
heterocycle catabolic process GO:0046700 167 0.011
divalent inorganic cation transport GO:0072511 134 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
cell growth GO:0016049 104 0.011
developmental growth GO:0048589 100 0.011
oxidation reduction process GO:0055114 304 0.011
negative regulation of nervous system development GO:0051961 79 0.011
microtubule organizing center organization GO:0031023 1 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
cellular macromolecule localization GO:0070727 122 0.010
calcium ion homeostasis GO:0055074 162 0.010
regulation of growth GO:0040008 105 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010
neuron projection morphogenesis GO:0048812 122 0.010
negative regulation of molecular function GO:0044092 133 0.010
regulation of cellular localization GO:0060341 263 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
regulation of response to stress GO:0080134 126 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
response to nutrient GO:0007584 248 0.010
negative regulation of secretion GO:0051048 82 0.010
cyclic nucleotide metabolic process GO:0009187 80 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.010
cellular response to lipid GO:0071396 201 0.010
neural crest cell differentiation GO:0014033 2 0.010

Ercc8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.036
disease of metabolism DOID:0014667 0 0.014
retinal disease DOID:5679 0 0.010
retinal degeneration DOID:8466 0 0.010
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010