Rattus norvegicus

0 known processes

Heca

headcase homolog (Drosophila)

Heca biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
intracellular signal transduction GO:0035556 314 0.077
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.072
nucleic acid templated transcription GO:0097659 379 0.061
regulation of transcription dna templated GO:0006355 374 0.054
transcription dna templated GO:0006351 377 0.053
regulation of cellular protein metabolic process GO:0032268 267 0.051
regulation of phosphorus metabolic process GO:0051174 349 0.049
regulation of rna biosynthetic process GO:2001141 381 0.045
protein phosphorylation GO:0006468 345 0.045
regulation of cell differentiation GO:0045595 320 0.045
positive regulation of cellular protein metabolic process GO:0032270 167 0.044
transcription from rna polymerase ii promoter GO:0006366 252 0.044
regulation of signal transduction GO:0009966 318 0.043
apoptotic process GO:0006915 381 0.043
regulation of cell development GO:0060284 263 0.041
rna biosynthetic process GO:0032774 380 0.041
regulation of cell proliferation GO:0042127 359 0.039
vesicle mediated transport GO:0016192 181 0.038
regulation of nucleic acid templated transcription GO:1903506 380 0.037
regulation of intracellular signal transduction GO:1902531 218 0.037
regulation of protein metabolic process GO:0051246 289 0.036
regulation of cellular ketone metabolic process GO:0010565 27 0.036
programmed cell death GO:0012501 392 0.036
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
regulation of apoptotic process GO:0042981 335 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.034
head development GO:0060322 247 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
negative regulation of metabolic process GO:0009892 331 0.032
regulation of rna metabolic process GO:0051252 391 0.032
positive regulation of developmental process GO:0051094 283 0.032
positive regulation of biosynthetic process GO:0009891 319 0.031
positive regulation of cell differentiation GO:0045597 217 0.031
reproductive process GO:0022414 372 0.031
regulation of protein modification process GO:0031399 194 0.030
rna metabolic process GO:0016070 406 0.030
carbohydrate derivative metabolic process GO:1901135 346 0.029
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
cellular ketone metabolic process GO:0042180 51 0.028
regulation of molecular function GO:0065009 398 0.028
response to peptide GO:1901652 292 0.027
organophosphate metabolic process GO:0019637 370 0.026
amine metabolic process GO:0009308 38 0.026
catabolic process GO:0009056 351 0.026
response to cytokine GO:0034097 215 0.026
cellular response to stress GO:0033554 269 0.026
negative regulation of cellular biosynthetic process GO:0031327 161 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
regulation of phosphate metabolic process GO:0019220 349 0.025
proteolysis GO:0006508 175 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
positive regulation of catalytic activity GO:0043085 184 0.025
response to extracellular stimulus GO:0009991 380 0.025
regulation of nervous system development GO:0051960 264 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
cellular amino acid metabolic process GO:0006520 107 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
multicellular organism reproduction GO:0032504 233 0.024
cell cycle checkpoint GO:0000075 2 0.024
protein oligomerization GO:0051259 191 0.023
single organism reproductive process GO:0044702 297 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
negative regulation of signaling GO:0023057 157 0.023
negative regulation of programmed cell death GO:0043069 183 0.023
regulation of programmed cell death GO:0043067 341 0.023
cellular response to hormone stimulus GO:0032870 247 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
carbohydrate derivative biosynthetic process GO:1901137 124 0.022
regulation of neurogenesis GO:0050767 247 0.022
negative regulation of rna metabolic process GO:0051253 123 0.022
purine nucleoside metabolic process GO:0042278 169 0.022
dephosphorylation GO:0016311 98 0.022
carboxylic acid metabolic process GO:0019752 289 0.021
cellular amine metabolic process GO:0044106 38 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.021
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.021
negative regulation of gene expression GO:0010629 199 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
negative regulation of cell death GO:0060548 229 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
nitrogen compound transport GO:0071705 229 0.021
response to estrogen GO:0043627 232 0.020
response to nutrient levels GO:0031667 370 0.020
organic substance catabolic process GO:1901575 316 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
positive regulation of molecular function GO:0044093 230 0.020
regulation of hydrolase activity GO:0051336 143 0.020
aging GO:0007568 241 0.020
positive regulation of cell development GO:0010720 176 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
purine containing compound metabolic process GO:0072521 253 0.019
homeostatic process GO:0042592 331 0.019
negative regulation of cell communication GO:0010648 158 0.019
ras protein signal transduction GO:0007265 29 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
response to oxidative stress GO:0006979 186 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
positive regulation of gene expression GO:0010628 244 0.019
positive regulation of transcription dna templated GO:0045893 197 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
single organism biosynthetic process GO:0044711 342 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
negative regulation of rna biosynthetic process GO:1902679 118 0.018
macromolecule localization GO:0033036 252 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
cellular catabolic process GO:0044248 295 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
response to decreased oxygen levels GO:0036293 237 0.018
response to peptide hormone GO:0043434 278 0.017
protein complex subunit organization GO:0071822 302 0.017
oxoacid metabolic process GO:0043436 290 0.017
central nervous system development GO:0007417 311 0.017
regeneration GO:0031099 163 0.017
regulation of neuron projection development GO:0010975 161 0.017
regulation of phosphorylation GO:0042325 248 0.017
cell cycle GO:0007049 101 0.017
organophosphate catabolic process GO:0046434 148 0.016
response to inorganic substance GO:0010035 377 0.016
neuron death GO:0070997 127 0.016
positive regulation of cell death GO:0010942 184 0.016
multi organism reproductive process GO:0044703 262 0.016
neuron differentiation GO:0030182 368 0.016
cellular macromolecule localization GO:0070727 122 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
positive regulation of signaling GO:0023056 270 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
organelle organization GO:0006996 266 0.015
cellular response to cytokine stimulus GO:0071345 127 0.015
amide transport GO:0042886 105 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
positive regulation of nervous system development GO:0051962 178 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
cellular component biogenesis GO:0044085 368 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
wound healing GO:0042060 122 0.015
regulation of catalytic activity GO:0050790 304 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
muscle structure development GO:0061061 87 0.015
dna integrity checkpoint GO:0031570 2 0.015
single organism cellular localization GO:1902580 102 0.014
regulation of catabolic process GO:0009894 113 0.014
cellular component assembly GO:0022607 360 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
aromatic compound catabolic process GO:0019439 168 0.014
response to oxygen levels GO:0070482 265 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
immune response GO:0006955 104 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
macromolecular complex subunit organization GO:0043933 339 0.013
multicellular organism growth GO:0035264 1 0.013
cell type specific apoptotic process GO:0097285 134 0.013
response to hypoxia GO:0001666 231 0.013
brain development GO:0007420 247 0.013
regulation of response to external stimulus GO:0032101 106 0.013
establishment of protein localization GO:0045184 141 0.013
developmental process involved in reproduction GO:0003006 159 0.013
cell projection organization GO:0030030 302 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
regulation of proteasomal protein catabolic process GO:0061136 4 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
single organism organelle organization GO:1902589 180 0.013
regulation of cell projection organization GO:0031344 175 0.013
positive regulation of neurogenesis GO:0050769 165 0.012
cellular response to oxygen containing compound GO:1901701 386 0.012
apoptotic signaling pathway GO:0097190 27 0.012
cellular chemical homeostasis GO:0055082 247 0.012
male gamete generation GO:0048232 99 0.012
lipid metabolic process GO:0006629 283 0.012
negative regulation of molecular function GO:0044092 133 0.012
nucleoside catabolic process GO:0009164 126 0.012
muscle cell differentiation GO:0042692 52 0.012
protein maturation GO:0051604 68 0.012
single organism catabolic process GO:0044712 283 0.012
sexual reproduction GO:0019953 148 0.012
regulation of cellular component organization GO:0051128 368 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
peptidyl amino acid modification GO:0018193 126 0.012
intracellular transport GO:0046907 185 0.012
regulation of neuron differentiation GO:0045664 208 0.012
mitotic spindle organization GO:0007052 2 0.012
cellular component movement GO:0006928 248 0.012
negative regulation of transport GO:0051051 136 0.012
cellular homeostasis GO:0019725 252 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
response to estradiol GO:0032355 164 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
negative regulation of neuron death GO:1901215 69 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
nucleocytoplasmic transport GO:0006913 48 0.011
immune effector process GO:0002252 53 0.011
spermatogenesis GO:0007283 99 0.011
cellular protein localization GO:0034613 122 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
positive regulation of organelle organization GO:0010638 48 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
response to other organism GO:0051707 220 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
neurological system process GO:0050877 219 0.011
neuron projection development GO:0031175 273 0.011
peptide transport GO:0015833 97 0.011
positive regulation of ion transport GO:0043270 94 0.011
response to lipopolysaccharide GO:0032496 191 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
growth GO:0040007 165 0.011
protein processing GO:0016485 68 0.011
nucleotide metabolic process GO:0009117 279 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
locomotion GO:0040011 237 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
response to metal ion GO:0010038 253 0.011
heterocycle catabolic process GO:0046700 167 0.011
neuron development GO:0048666 286 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
cell projection morphogenesis GO:0048858 123 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
regulation of hormone levels GO:0010817 187 0.010
nucleoside metabolic process GO:0009116 179 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010
chemical homeostasis GO:0048878 292 0.010
purine ribonucleotide biosynthetic process GO:0009152 81 0.010
regulation of neuron apoptotic process GO:0043523 83 0.010
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 1 0.010
cellular response to oxidative stress GO:0034599 76 0.010
neuron apoptotic process GO:0051402 88 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
positive regulation of cell communication GO:0010647 271 0.010
positive regulation of secretion GO:0051047 140 0.010

Heca disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
musculoskeletal system disease DOID:17 0 0.012
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010