Rattus norvegicus

2 known processes

Dgat2

diacylglycerol O-acyltransferase homolog 2 (mouse)

(Aliases: MGC108863)

Dgat2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular lipid metabolic process GO:0044255 208 0.224
Human
organic acid metabolic process GO:0006082 292 0.210
carboxylic acid metabolic process GO:0019752 289 0.148
organophosphate metabolic process GO:0019637 370 0.115
organic substance catabolic process GO:1901575 316 0.109
single organism biosynthetic process GO:0044711 342 0.095
Human
oxoacid metabolic process GO:0043436 290 0.094
response to extracellular stimulus GO:0009991 380 0.083
positive regulation of signaling GO:0023056 270 0.076
response to nutrient levels GO:0031667 370 0.071
positive regulation of multicellular organismal process GO:0051240 387 0.071
positive regulation of cell communication GO:0010647 271 0.068
lipid metabolic process GO:0006629 283 0.063
Human
cellular response to oxygen containing compound GO:1901701 386 0.062
regulation of signal transduction GO:0009966 318 0.061
monocarboxylic acid metabolic process GO:0032787 152 0.060
secretion GO:0046903 307 0.060
response to nutrient GO:0007584 248 0.060
reproductive process GO:0022414 372 0.056
cellular amino acid metabolic process GO:0006520 107 0.054
lipid biosynthetic process GO:0008610 128 0.053
Human
response to peptide GO:1901652 292 0.052
positive regulation of developmental process GO:0051094 283 0.052
response to hypoxia GO:0001666 231 0.050
response to glucocorticoid GO:0051384 223 0.050
single organism catabolic process GO:0044712 283 0.050
programmed cell death GO:0012501 392 0.050
cell cell signaling GO:0007267 335 0.047
homeostatic process GO:0042592 331 0.046
glycerolipid metabolic process GO:0046486 67 0.044
Human
regulation of rna metabolic process GO:0051252 391 0.043
reproduction GO:0000003 245 0.042
cellular ketone metabolic process GO:0042180 51 0.041
secretion by cell GO:0032940 248 0.040
positive regulation of transport GO:0051050 245 0.039
response to metal ion GO:0010038 253 0.039
positive regulation of lipid catabolic process GO:0050996 4 0.039
single organism reproductive process GO:0044702 297 0.038
regulation of cellular protein metabolic process GO:0032268 267 0.038
regulation of cellular ketone metabolic process GO:0010565 27 0.038
negative regulation of metabolic process GO:0009892 331 0.038
response to peptide hormone GO:0043434 278 0.038
chemical homeostasis GO:0048878 292 0.037
hormone secretion GO:0046879 115 0.036
regulation of multicellular organismal development GO:2000026 376 0.036
positive regulation of protein metabolic process GO:0051247 178 0.036
apoptotic process GO:0006915 381 0.036
transcription dna templated GO:0006351 377 0.035
multi organism reproductive process GO:0044703 262 0.034
nucleoside phosphate metabolic process GO:0006753 283 0.034
regulation of protein metabolic process GO:0051246 289 0.034
cellular amine metabolic process GO:0044106 38 0.034
catabolic process GO:0009056 351 0.034
regulation of hormone levels GO:0010817 187 0.034
signal release GO:0023061 145 0.034
neuron differentiation GO:0030182 368 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.033
small molecule biosynthetic process GO:0044283 124 0.033
cellular catabolic process GO:0044248 295 0.033
rna biosynthetic process GO:0032774 380 0.033
response to inorganic substance GO:0010035 377 0.032
organophosphate biosynthetic process GO:0090407 143 0.032
positive regulation of response to stimulus GO:0048584 285 0.032
regulation of lipid metabolic process GO:0019216 68 0.031
nucleic acid templated transcription GO:0097659 379 0.031
regulation of cellular localization GO:0060341 263 0.031
regulation of rna biosynthetic process GO:2001141 381 0.031
response to oxygen levels GO:0070482 265 0.031
regulation of secretion GO:0051046 224 0.031
nitrogen compound transport GO:0071705 229 0.031
response to carbohydrate GO:0009743 183 0.031
tissue development GO:0009888 252 0.031
response to acid chemical GO:0001101 222 0.030
nucleotide metabolic process GO:0009117 279 0.030
carboxylic acid biosynthetic process GO:0046394 83 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
oxidation reduction process GO:0055114 304 0.029
response to monosaccharide GO:0034284 159 0.029
response to ethanol GO:0045471 162 0.029
response to decreased oxygen levels GO:0036293 237 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.028
alpha amino acid metabolic process GO:1901605 71 0.028
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.028
protein oligomerization GO:0051259 191 0.028
regulation of apoptotic process GO:0042981 335 0.028
positive regulation of triglyceride metabolic process GO:0090208 4 0.028
fatty acid metabolic process GO:0006631 99 0.027
regulation of molecular function GO:0065009 398 0.027
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.027
cofactor metabolic process GO:0051186 95 0.027
Human
amine metabolic process GO:0009308 38 0.027
regulation of transcription dna templated GO:0006355 374 0.027
regulation of programmed cell death GO:0043067 341 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
regulation of cellular component organization GO:0051128 368 0.026
triglyceride metabolic process GO:0006641 21 0.026
Human
organic acid biosynthetic process GO:0016053 83 0.026
carboxylic acid catabolic process GO:0046395 49 0.026
nicotinamide nucleotide metabolic process GO:0046496 28 0.026
multicellular organismal reproductive process GO:0048609 233 0.025
response to purine containing compound GO:0014074 126 0.025
cellular response to endogenous stimulus GO:0071495 377 0.025
regulation of protein phosphorylation GO:0001932 183 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
regulation of phosphate metabolic process GO:0019220 349 0.025
response to corticosteroid GO:0031960 235 0.025
regulation of hormone secretion GO:0046883 106 0.025
central nervous system development GO:0007417 311 0.024
regulation of cell proliferation GO:0042127 359 0.024
head development GO:0060322 247 0.024
rna metabolic process GO:0016070 406 0.024
regulation of cell development GO:0060284 263 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
regulation of anatomical structure morphogenesis GO:0022603 141 0.024
neuron development GO:0048666 286 0.024
regulation of nervous system development GO:0051960 264 0.024
positive regulation of cellular protein metabolic process GO:0032270 167 0.024
cellular homeostasis GO:0019725 252 0.023
regulation of phosphorylation GO:0042325 248 0.023
regulation of nucleic acid templated transcription GO:1903506 380 0.023
positive regulation of protein modification process GO:0031401 142 0.023
intracellular signal transduction GO:0035556 314 0.023
organonitrogen compound biosynthetic process GO:1901566 167 0.023
protein complex subunit organization GO:0071822 302 0.023
response to oxidative stress GO:0006979 186 0.023
sexual reproduction GO:0019953 148 0.023
cellular response to stress GO:0033554 269 0.023
organic acid transport GO:0015849 116 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
positive regulation of cellular component organization GO:0051130 200 0.022
multicellular organism reproduction GO:0032504 233 0.022
steroid metabolic process GO:0008202 73 0.022
peptide transport GO:0015833 97 0.022
hormone transport GO:0009914 121 0.021
amide transport GO:0042886 105 0.021
regulation of peptide hormone secretion GO:0090276 80 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
blood circulation GO:0008015 183 0.021
negative regulation of gene expression GO:0010629 199 0.021
acylglycerol metabolic process GO:0006639 21 0.021
Human
protein phosphorylation GO:0006468 345 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
response to organophosphorus GO:0046683 102 0.021
defense response GO:0006952 194 0.021
single organism behavior GO:0044708 130 0.020
response to hexose GO:0009746 144 0.020
peptide secretion GO:0002790 86 0.020
ion transmembrane transport GO:0034220 365 0.020
negative regulation of cell death GO:0060548 229 0.020
organic anion transport GO:0015711 132 0.020
proteolysis GO:0006508 175 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
response to glucose GO:0009749 136 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
regulation of catalytic activity GO:0050790 304 0.019
brain development GO:0007420 247 0.019
response to camp GO:0051591 91 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
regulation of protein modification process GO:0031399 194 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
protein complex assembly GO:0006461 263 0.019
regulation of peptide transport GO:0090087 87 0.019
alcohol metabolic process GO:0006066 77 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
anion transport GO:0006820 178 0.019
response to retinoic acid GO:0032526 63 0.019
pyridine containing compound metabolic process GO:0072524 32 0.019
positive regulation of neuron differentiation GO:0045666 126 0.019
growth GO:0040007 165 0.019
regulation of catabolic process GO:0009894 113 0.019
cellular response to lipid GO:0071396 201 0.018
positive regulation of cell development GO:0010720 176 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
circulatory system process GO:0003013 183 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
regulation of membrane potential GO:0042391 110 0.018
organic hydroxy compound metabolic process GO:1901615 115 0.018
negative regulation of signaling GO:0023057 157 0.018
cellular component assembly GO:0022607 360 0.018
regulation of system process GO:0044057 208 0.018
positive regulation of molecular function GO:0044093 230 0.017
cellular component biogenesis GO:0044085 368 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
gamete generation GO:0007276 124 0.017
regulation of neurogenesis GO:0050767 247 0.017
cellular chemical homeostasis GO:0055082 247 0.017
peptide hormone secretion GO:0030072 84 0.017
neuron projection development GO:0031175 273 0.017
ion homeostasis GO:0050801 212 0.017
regulation of kinase activity GO:0043549 117 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
regulation of response to stress GO:0080134 126 0.017
protein homooligomerization GO:0051260 91 0.017
regulation of secretion by cell GO:1903530 208 0.017
single organism carbohydrate metabolic process GO:0044723 118 0.016
inflammatory response GO:0006954 150 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
positive regulation of intracellular signal transduction GO:1902533 138 0.016
regulation of cell differentiation GO:0045595 320 0.016
action potential GO:0001508 54 0.016
cellular cation homeostasis GO:0030003 180 0.016
carbohydrate metabolic process GO:0005975 130 0.016
response to lipopolysaccharide GO:0032496 191 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
phospholipid metabolic process GO:0006644 61 0.016
response to insulin GO:0032868 133 0.016
negative regulation of cell communication GO:0010648 158 0.016
positive regulation of apoptotic process GO:0043065 154 0.015
neuron death GO:0070997 127 0.015
cation transport GO:0006812 382 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
organ regeneration GO:0031100 101 0.015
intracellular transport GO:0046907 185 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
reactive nitrogen species metabolic process GO:2001057 1 0.015
regulation of cell projection organization GO:0031344 175 0.015
positive regulation of signal transduction GO:0009967 175 0.015
anatomical structure morphogenesis GO:0009653 298 0.015
neutral lipid biosynthetic process GO:0046460 7 0.015
Human
macromolecular complex assembly GO:0065003 273 0.015
regulation of proteasomal protein catabolic process GO:0061136 4 0.015
synaptic transmission GO:0007268 235 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
cell type specific apoptotic process GO:0097285 134 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
protein localization GO:0008104 191 0.015
female pregnancy GO:0007565 122 0.015
organonitrogen compound catabolic process GO:1901565 179 0.014
localization of cell GO:0051674 202 0.014
organelle organization GO:0006996 266 0.014
energy derivation by oxidation of organic compounds GO:0015980 46 0.014
regulation of neuron death GO:1901214 115 0.014
liver development GO:0001889 90 0.014
response to growth factor GO:0070848 189 0.014
response to external biotic stimulus GO:0043207 221 0.014
small molecule catabolic process GO:0044282 59 0.014
heart morphogenesis GO:0003007 3 0.014
negative regulation of developmental process GO:0051093 125 0.014
mapk cascade GO:0000165 140 0.014
positive regulation of catabolic process GO:0009896 78 0.014
negative regulation of phosphate metabolic process GO:0045936 80 0.014
positive regulation of nervous system development GO:0051962 178 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
regulation of neuron projection development GO:0010975 161 0.014
regulation of cell motility GO:2000145 131 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
regulation of growth GO:0040008 105 0.013
response to wounding GO:0009611 254 0.013
regulation of peptide secretion GO:0002791 82 0.013
developmental process involved in reproduction GO:0003006 159 0.013
insulin secretion GO:0030073 69 0.013
axis specification GO:0009798 4 0.013
regulation of synaptic transmission GO:0050804 141 0.013
regulation of response to external stimulus GO:0032101 106 0.013
positive regulation of fatty acid beta oxidation GO:0032000 4 0.013
organic acid catabolic process GO:0016054 49 0.013
positive regulation of secretion GO:0051047 140 0.013
lipid modification GO:0030258 52 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
cellular response to acid chemical GO:0071229 75 0.013
regulation of neuron differentiation GO:0045664 208 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
response to ketone GO:1901654 182 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
gland development GO:0048732 155 0.013
ras protein signal transduction GO:0007265 29 0.013
monocarboxylic acid biosynthetic process GO:0072330 48 0.013
aging GO:0007568 241 0.013
regulation of cell migration GO:0030334 128 0.013
regulation of transferase activity GO:0051338 123 0.013
coenzyme metabolic process GO:0006732 86 0.013
Human
regulation of fatty acid metabolic process GO:0019217 18 0.013
transmembrane transport GO:0055085 412 0.013
multicellular organism growth GO:0035264 1 0.013
reproductive system development GO:0061458 128 0.013
acylglycerol biosynthetic process GO:0046463 7 0.012
Human
protein complex biogenesis GO:0070271 263 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
hepaticobiliary system development GO:0061008 90 0.012
single organism organelle organization GO:1902589 180 0.012
cell projection organization GO:0030030 302 0.012
negative regulation of transport GO:0051051 136 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
glycerol 3 phosphate metabolic process GO:0006072 2 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
cell migration GO:0016477 197 0.012
cation homeostasis GO:0055080 195 0.012
regulation of anatomical structure size GO:0090066 135 0.012
transmission of nerve impulse GO:0019226 42 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
response to bacterium GO:0009617 200 0.012
macromolecule localization GO:0033036 252 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
sterol homeostasis GO:0055092 3 0.012
cellular lipid catabolic process GO:0044242 37 0.012
circulatory system development GO:0072359 134 0.012
purine containing compound metabolic process GO:0072521 253 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
cellular response to external stimulus GO:0071496 118 0.011
chromosome segregation GO:0007059 2 0.011
positive regulation of peptide secretion GO:0002793 52 0.011
response to biotic stimulus GO:0009607 226 0.011
carbohydrate catabolic process GO:0016052 40 0.011
multicellular organismal signaling GO:0035637 44 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
neuronal action potential GO:0019228 35 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
response to cytokine GO:0034097 215 0.011
response to fatty acid GO:0070542 65 0.011
carboxylic acid transport GO:0046942 115 0.011
regulation of protein kinase activity GO:0045859 105 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
negative regulation of innate immune response GO:0045824 4 0.011
response to radiation GO:0009314 137 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
male gamete generation GO:0048232 99 0.011
spermatogenesis GO:0007283 99 0.011
cytokine production GO:0001816 61 0.011
lipid catabolic process GO:0016042 46 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
regulation of body fluid levels GO:0050878 90 0.011
locomotion GO:0040011 237 0.011
rhythmic process GO:0048511 156 0.011
response to temperature stimulus GO:0009266 94 0.011
response to vitamin GO:0033273 131 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
regulation of fat cell differentiation GO:0045598 3 0.011
response to activity GO:0014823 73 0.011
cellular component movement GO:0006928 248 0.011
nucleoside metabolic process GO:0009116 179 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
positive regulation of rna biosynthetic process GO:1902680 197 0.010
positive regulation of gene expression GO:0010628 244 0.010
cation transmembrane transport GO:0098655 263 0.010
cellular amino acid catabolic process GO:0009063 21 0.010
dephosphorylation GO:0016311 98 0.010
non canonical wnt signaling pathway GO:0035567 3 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
embryonic pattern specification GO:0009880 1 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
positive regulation of cell death GO:0010942 184 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
ribose phosphate biosynthetic process GO:0046390 87 0.010
lipid storage GO:0019915 1 0.010
negative regulation of molecular function GO:0044092 133 0.010
anion transmembrane transport GO:0098656 77 0.010

Dgat2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
disease of metabolism DOID:0014667 0 0.019
musculoskeletal system disease DOID:17 0 0.017
inherited metabolic disorder DOID:655 0 0.013
central nervous system disease DOID:331 0 0.012
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011