Rattus norvegicus

78 known processes

Mat2a

methionine adenosyltransferase II, alpha

(Aliases: Sams2)

Mat2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to radiation GO:0009314 137 0.116
rna metabolic process GO:0016070 406 0.085
positive regulation of gene expression GO:0010628 244 0.070
anatomical structure morphogenesis GO:0009653 298 0.070
regulation of molecular function GO:0065009 398 0.064
organic acid metabolic process GO:0006082 292 0.058
nucleic acid templated transcription GO:0097659 379 0.056
regulation of rna metabolic process GO:0051252 391 0.053
single organism organelle organization GO:1902589 180 0.053
regulation of rna biosynthetic process GO:2001141 381 0.049
regulation of mapk cascade GO:0043408 116 0.047
rhythmic process GO:0048511 156 0.047
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.046
amine metabolic process GO:0009308 38 0.045
organonitrogen compound biosynthetic process GO:1901566 167 0.044
single organism biosynthetic process GO:0044711 342 0.044
coenzyme metabolic process GO:0006732 86 0.043
mitotic spindle organization GO:0007052 2 0.043
response to oxidative stress GO:0006979 186 0.042
intracellular signal transduction GO:0035556 314 0.042
transcription from rna polymerase ii promoter GO:0006366 252 0.042
regulation of mrna splicing via spliceosome GO:0048024 3 0.042
rna biosynthetic process GO:0032774 380 0.042
negative regulation of cellular metabolic process GO:0031324 281 0.041
carbohydrate derivative metabolic process GO:1901135 346 0.040
signal transduction by phosphorylation GO:0023014 144 0.040
catabolic process GO:0009056 351 0.040
cellular amino acid metabolic process GO:0006520 107 0.040
mrna stabilization GO:0048255 2 0.039
cellular modified amino acid metabolic process GO:0006575 61 0.039
multicellular organism reproduction GO:0032504 233 0.039
single organism catabolic process GO:0044712 283 0.038
cofactor metabolic process GO:0051186 95 0.038
defense response GO:0006952 194 0.038
circadian regulation of gene expression GO:0032922 3 0.037
cellular amine metabolic process GO:0044106 38 0.037
cellular response to oxygen containing compound GO:1901701 386 0.037
reproductive process GO:0022414 372 0.036
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.036
response to inorganic substance GO:0010035 377 0.034
organelle organization GO:0006996 266 0.034
positive regulation of multicellular organismal process GO:0051240 387 0.034
response to metal ion GO:0010038 253 0.034
positive regulation of cellular component organization GO:0051130 200 0.034
response to wounding GO:0009611 254 0.032
positive regulation of cell differentiation GO:0045597 217 0.032
neurological system process GO:0050877 219 0.031
positive regulation of developmental process GO:0051094 283 0.031
transmembrane transport GO:0055085 412 0.031
regulation of cell cycle GO:0051726 73 0.031
cell cycle GO:0007049 101 0.031
multicellular organism growth GO:0035264 1 0.030
reproduction GO:0000003 245 0.030
regulation of multicellular organismal development GO:2000026 376 0.030
cellular component biogenesis GO:0044085 368 0.030
multicellular organismal reproductive process GO:0048609 233 0.029
negative regulation of gene expression GO:0010629 199 0.029
brain development GO:0007420 247 0.029
sexual reproduction GO:0019953 148 0.029
response to alkaloid GO:0043279 132 0.029
cellular chemical homeostasis GO:0055082 247 0.028
organic substance catabolic process GO:1901575 316 0.028
cellular catabolic process GO:0044248 295 0.028
regulation of organelle organization GO:0033043 80 0.028
locomotion GO:0040011 237 0.027
regulation of transcription dna templated GO:0006355 374 0.027
inflammatory response GO:0006954 150 0.027
spindle organization GO:0007051 2 0.027
meiotic cell cycle process GO:1903046 3 0.027
regulation of neurogenesis GO:0050767 247 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
multi organism reproductive process GO:0044703 262 0.026
protein complex subunit organization GO:0071822 302 0.026
cation transport GO:0006812 382 0.025
cell projection organization GO:0030030 302 0.025
carboxylic acid metabolic process GO:0019752 289 0.025
circadian rhythm GO:0007623 88 0.025
growth GO:0040007 165 0.025
aging GO:0007568 241 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
neuron development GO:0048666 286 0.024
regulation of cell differentiation GO:0045595 320 0.023
regulation of nucleic acid templated transcription GO:1903506 380 0.023
cell cell signaling GO:0007267 335 0.023
cell cycle process GO:0022402 57 0.023
response to decreased oxygen levels GO:0036293 237 0.023
cellular response to stress GO:0033554 269 0.022
programmed cell death GO:0012501 392 0.022
glycosyl compound metabolic process GO:1901657 182 0.022
regulation of protein metabolic process GO:0051246 289 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
head development GO:0060322 247 0.021
mitotic cell cycle GO:0000278 49 0.021
regulation of synaptic transmission GO:0050804 141 0.021
gamete generation GO:0007276 124 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.020
regulation of phosphate metabolic process GO:0019220 349 0.020
negative regulation of molecular function GO:0044092 133 0.020
response to oxygen levels GO:0070482 265 0.020
reactive oxygen species metabolic process GO:0072593 37 0.020
regulation of cell development GO:0060284 263 0.019
regulation of phosphorylation GO:0042325 248 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
regulation of programmed cell death GO:0043067 341 0.019
protein localization GO:0008104 191 0.018
axis specification GO:0009798 4 0.018
macromolecular complex assembly GO:0065003 273 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
negative regulation of metabolic process GO:0009892 331 0.018
cellular response to endogenous stimulus GO:0071495 377 0.018
protein refolding GO:0042026 3 0.018
negative regulation of apoptotic process GO:0043066 181 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
positive regulation of locomotion GO:0040017 102 0.017
positive regulation of cell death GO:0010942 184 0.017
chemical homeostasis GO:0048878 292 0.017
regulation of neuron differentiation GO:0045664 208 0.017
purine containing compound metabolic process GO:0072521 253 0.017
cellular response to abiotic stimulus GO:0071214 85 0.017
positive regulation of biosynthetic process GO:0009891 319 0.017
nucleotide metabolic process GO:0009117 279 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
alternative mrna splicing via spliceosome GO:0000380 4 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
regulation of secretion by cell GO:1903530 208 0.016
synaptic transmission GO:0007268 235 0.016
neuron death GO:0070997 127 0.016
embryonic pattern specification GO:0009880 1 0.016
negative regulation of cell death GO:0060548 229 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
regulation of cell projection organization GO:0031344 175 0.015
response to acid chemical GO:0001101 222 0.015
developmental growth GO:0048589 100 0.015
nitrogen compound transport GO:0071705 229 0.015
response to carbohydrate GO:0009743 183 0.015
regulation of growth GO:0040008 105 0.015
regulation of mrna stability GO:0043488 3 0.015
b cell differentiation GO:0030183 2 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
anatomical structure formation involved in morphogenesis GO:0048646 83 0.015
central nervous system development GO:0007417 311 0.015
neuron projection development GO:0031175 273 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
mesoderm morphogenesis GO:0048332 1 0.015
secretion GO:0046903 307 0.015
regulation of apoptotic process GO:0042981 335 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.015
neuron differentiation GO:0030182 368 0.015
circulatory system development GO:0072359 134 0.014
chromatin modification GO:0016568 33 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
response to peptide hormone GO:0043434 278 0.014
epithelial cell differentiation GO:0030855 71 0.014
secretion by cell GO:0032940 248 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
response to hypoxia GO:0001666 231 0.014
ion homeostasis GO:0050801 212 0.014
transcription dna templated GO:0006351 377 0.014
muscle structure development GO:0061061 87 0.014
rna stabilization GO:0043489 2 0.014
cellular homeostasis GO:0019725 252 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
regulation of rna stability GO:0043487 3 0.014
immune response GO:0006955 104 0.014
response to hyperoxia GO:0055093 45 0.014
male gamete generation GO:0048232 99 0.014
positive regulation of cell development GO:0010720 176 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
spermatogenesis GO:0007283 99 0.013
regulation of response to stress GO:0080134 126 0.013
single organism reproductive process GO:0044702 297 0.013
response to ammonium ion GO:0060359 71 0.013
regulation of neuron projection development GO:0010975 161 0.013
cellular ketone metabolic process GO:0042180 51 0.013
response to increased oxygen levels GO:0036296 45 0.013
cytoskeleton organization GO:0007010 111 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
glucose homeostasis GO:0042593 75 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
organophosphate metabolic process GO:0019637 370 0.013
cellular response to oxidative stress GO:0034599 76 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
mrna metabolic process GO:0016071 20 0.013
response to nutrient levels GO:0031667 370 0.013
tissue development GO:0009888 252 0.012
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
cell cycle checkpoint GO:0000075 2 0.012
regulation of cell proliferation GO:0042127 359 0.012
response to peptide GO:1901652 292 0.012
photoperiodism GO:0009648 4 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
alpha amino acid metabolic process GO:1901605 71 0.012
cellular component assembly GO:0022607 360 0.012
regulation of mesenchymal cell proliferation GO:0010464 4 0.012
macromolecule localization GO:0033036 252 0.012
sensory perception GO:0007600 101 0.012
regulation of signal transduction GO:0009966 318 0.012
apoptotic process GO:0006915 381 0.012
centrosome organization GO:0051297 1 0.012
cellular cation homeostasis GO:0030003 180 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.012
cellular response to lipid GO:0071396 201 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
regulation of nervous system development GO:0051960 264 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
response to other organism GO:0051707 220 0.012
protein oligomerization GO:0051259 191 0.012
regulation of circadian rhythm GO:0042752 27 0.012
oxoacid metabolic process GO:0043436 290 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
cellular metal ion homeostasis GO:0006875 172 0.011
wound healing GO:0042060 122 0.011
multicellular organismal signaling GO:0035637 44 0.011
carboxylic acid biosynthetic process GO:0046394 83 0.011
sulfur compound metabolic process GO:0006790 70 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
response to monosaccharide GO:0034284 159 0.011
response to temperature stimulus GO:0009266 94 0.011
response to growth factor GO:0070848 189 0.011
carbohydrate homeostasis GO:0033500 75 0.011
anion transmembrane transport GO:0098656 77 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
response to nutrient GO:0007584 248 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
response to extracellular stimulus GO:0009991 380 0.011
negative regulation of cell communication GO:0010648 158 0.011
behavior GO:0007610 205 0.011
regulation of anatomical structure size GO:0090066 135 0.011
negative regulation of transport GO:0051051 136 0.011
mapk cascade GO:0000165 140 0.011
lipid metabolic process GO:0006629 283 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
cytoskeleton dependent cytokinesis GO:0061640 2 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
chromosome organization GO:0051276 36 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
ribonucleoside metabolic process GO:0009119 174 0.010
anion transport GO:0006820 178 0.010
cellular ion homeostasis GO:0006873 184 0.010
protein phosphorylation GO:0006468 345 0.010
response to toxic substance GO:0009636 133 0.010
embryo development GO:0009790 49 0.010
negative regulation of circadian rhythm GO:0042754 5 0.010
regulation of catalytic activity GO:0050790 304 0.010

Mat2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
musculoskeletal system disease DOID:17 0 0.021
sensory system disease DOID:0050155 0 0.013
nervous system disease DOID:863 0 0.013