Rattus norvegicus

0 known processes

Tmem120a

transmembrane protein 120A

(Aliases: Tmpit,RGD1311474)

Tmem120a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism biosynthetic process GO:0044711 342 0.315
apoptotic process GO:0006915 381 0.197
oxoacid metabolic process GO:0043436 290 0.183
carboxylic acid metabolic process GO:0019752 289 0.146
programmed cell death GO:0012501 392 0.135
regulation of programmed cell death GO:0043067 341 0.124
small molecule biosynthetic process GO:0044283 124 0.124
cellular amino acid metabolic process GO:0006520 107 0.119
regulation of apoptotic process GO:0042981 335 0.118
response to inorganic substance GO:0010035 377 0.114
organic acid metabolic process GO:0006082 292 0.113
lipid metabolic process GO:0006629 283 0.107
organonitrogen compound biosynthetic process GO:1901566 167 0.095
oxidation reduction process GO:0055114 304 0.094
negative regulation of cellular metabolic process GO:0031324 281 0.092
anatomical structure morphogenesis GO:0009653 298 0.091
macromolecule localization GO:0033036 252 0.085
response to cytokine GO:0034097 215 0.083
reproductive process GO:0022414 372 0.080
regulation of cell proliferation GO:0042127 359 0.080
glycerolipid metabolic process GO:0046486 67 0.077
negative regulation of apoptotic process GO:0043066 181 0.072
cellular lipid metabolic process GO:0044255 208 0.071
organic acid biosynthetic process GO:0016053 83 0.070
aging GO:0007568 241 0.067
lipid biosynthetic process GO:0008610 128 0.066
response to nutrient levels GO:0031667 370 0.063
regulation of molecular function GO:0065009 398 0.062
response to extracellular stimulus GO:0009991 380 0.062
response to nutrient GO:0007584 248 0.059
negative regulation of programmed cell death GO:0043069 183 0.059
multi organism reproductive process GO:0044703 262 0.059
rna biosynthetic process GO:0032774 380 0.057
cellular component biogenesis GO:0044085 368 0.057
single organism reproductive process GO:0044702 297 0.055
response to metal ion GO:0010038 253 0.054
homeostatic process GO:0042592 331 0.054
regulation of catalytic activity GO:0050790 304 0.054
organophosphate biosynthetic process GO:0090407 143 0.052
protein complex assembly GO:0006461 263 0.051
negative regulation of macromolecule metabolic process GO:0010605 260 0.051
cellular homeostasis GO:0019725 252 0.049
negative regulation of metabolic process GO:0009892 331 0.049
response to oxidative stress GO:0006979 186 0.049
single organism intracellular transport GO:1902582 166 0.047
negative regulation of cell death GO:0060548 229 0.047
regulation of protein phosphorylation GO:0001932 183 0.046
cellular ketone metabolic process GO:0042180 51 0.046
negative regulation of protein metabolic process GO:0051248 114 0.046
circulatory system process GO:0003013 183 0.043
regulation of cellular protein metabolic process GO:0032268 267 0.043
reproduction GO:0000003 245 0.043
transmembrane transport GO:0055085 412 0.042
organophosphate metabolic process GO:0019637 370 0.042
cellular amine metabolic process GO:0044106 38 0.041
regulation of rna biosynthetic process GO:2001141 381 0.041
macromolecular complex assembly GO:0065003 273 0.041
nucleic acid templated transcription GO:0097659 379 0.041
cation transport GO:0006812 382 0.040
response to external biotic stimulus GO:0043207 221 0.040
cell type specific apoptotic process GO:0097285 134 0.040
intracellular transport GO:0046907 185 0.039
positive regulation of cell differentiation GO:0045597 217 0.039
response to toxic substance GO:0009636 133 0.039
positive regulation of developmental process GO:0051094 283 0.039
ion transmembrane transport GO:0034220 365 0.039
central nervous system development GO:0007417 311 0.038
organelle organization GO:0006996 266 0.037
alcohol metabolic process GO:0006066 77 0.037
response to hypoxia GO:0001666 231 0.037
brain development GO:0007420 247 0.037
regulation of cellular component organization GO:0051128 368 0.036
positive regulation of biosynthetic process GO:0009891 319 0.036
phospholipid metabolic process GO:0006644 61 0.036
response to oxygen levels GO:0070482 265 0.036
response to ketone GO:1901654 182 0.035
positive regulation of multicellular organismal process GO:0051240 387 0.035
cellular modified amino acid metabolic process GO:0006575 61 0.035
positive regulation of programmed cell death GO:0043068 157 0.034
regulation of phosphorus metabolic process GO:0051174 349 0.034
neuron differentiation GO:0030182 368 0.034
regulation of phosphate metabolic process GO:0019220 349 0.034
cellular response to stress GO:0033554 269 0.034
negative regulation of molecular function GO:0044092 133 0.034
intracellular signal transduction GO:0035556 314 0.033
amine metabolic process GO:0009308 38 0.033
cation transmembrane transport GO:0098655 263 0.033
macromolecular complex subunit organization GO:0043933 339 0.033
cellular response to endogenous stimulus GO:0071495 377 0.033
cellular catabolic process GO:0044248 295 0.033
cellular component assembly GO:0022607 360 0.033
regulation of lipid metabolic process GO:0019216 68 0.033
defense response GO:0006952 194 0.033
regulation of cell differentiation GO:0045595 320 0.032
regulation of transcription dna templated GO:0006355 374 0.032
negative regulation of cellular protein metabolic process GO:0032269 106 0.032
response to decreased oxygen levels GO:0036293 237 0.032
response to peptide hormone GO:0043434 278 0.032
cellular response to cytokine stimulus GO:0071345 127 0.032
response to peptide GO:1901652 292 0.032
response to acid chemical GO:0001101 222 0.032
positive regulation of apoptotic process GO:0043065 154 0.031
regulation of multicellular organismal development GO:2000026 376 0.031
multicellular organismal reproductive process GO:0048609 233 0.031
chemical homeostasis GO:0048878 292 0.031
positive regulation of cell death GO:0010942 184 0.031
cell migration GO:0016477 197 0.031
single organism cellular localization GO:1902580 102 0.031
organic hydroxy compound metabolic process GO:1901615 115 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
regulation of protein metabolic process GO:0051246 289 0.030
alpha amino acid metabolic process GO:1901605 71 0.030
regulation of cellular ketone metabolic process GO:0010565 27 0.030
response to estrogen GO:0043627 232 0.030
organic hydroxy compound biosynthetic process GO:1901617 51 0.029
protein phosphorylation GO:0006468 345 0.029
head development GO:0060322 247 0.029
response to glucocorticoid GO:0051384 223 0.029
secretion by cell GO:0032940 248 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
negative regulation of cell proliferation GO:0008285 119 0.028
cellular response to oxygen containing compound GO:1901701 386 0.028
response to bacterium GO:0009617 200 0.028
cardiovascular system development GO:0072358 134 0.028
cellular response to hormone stimulus GO:0032870 247 0.027
regulation of phosphorylation GO:0042325 248 0.027
metal ion homeostasis GO:0055065 186 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
response to purine containing compound GO:0014074 126 0.027
cellular lipid catabolic process GO:0044242 37 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
nitrogen compound transport GO:0071705 229 0.027
cation homeostasis GO:0055080 195 0.027
reactive oxygen species metabolic process GO:0072593 37 0.027
divalent metal ion transport GO:0070838 132 0.026
regulation of neuron apoptotic process GO:0043523 83 0.026
response to biotic stimulus GO:0009607 226 0.026
positive regulation of signal transduction GO:0009967 175 0.026
response to alkaloid GO:0043279 132 0.026
establishment of protein localization GO:0045184 141 0.026
response to lipopolysaccharide GO:0032496 191 0.026
cell projection organization GO:0030030 302 0.026
alcohol biosynthetic process GO:0046165 38 0.026
positive regulation of response to stimulus GO:0048584 285 0.025
rna metabolic process GO:0016070 406 0.025
cellular macromolecule localization GO:0070727 122 0.025
cytokine production GO:0001816 61 0.025
protein localization GO:0008104 191 0.025
cellular amide metabolic process GO:0043603 44 0.025
protein complex subunit organization GO:0071822 302 0.025
regulation of nervous system development GO:0051960 264 0.025
regulation of growth GO:0040008 105 0.025
negative regulation of gene expression GO:0010629 199 0.024
multicellular organism reproduction GO:0032504 233 0.024
protein transport GO:0015031 132 0.024
protein oligomerization GO:0051259 191 0.024
lipid oxidation GO:0034440 30 0.024
lipid modification GO:0030258 52 0.024
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.023
positive regulation of molecular function GO:0044093 230 0.023
response to molecule of bacterial origin GO:0002237 194 0.023
response to corticosteroid GO:0031960 235 0.023
positive regulation of cell communication GO:0010647 271 0.023
protein localization to organelle GO:0033365 57 0.023
protein complex biogenesis GO:0070271 263 0.023
gamete generation GO:0007276 124 0.023
regulation of rna metabolic process GO:0051252 391 0.023
positive regulation of transcription dna templated GO:0045893 197 0.022
regulation of anatomical structure size GO:0090066 135 0.022
sexual reproduction GO:0019953 148 0.022
positive regulation of lipid catabolic process GO:0050996 4 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
regulation of hormone levels GO:0010817 187 0.022
developmental process involved in reproduction GO:0003006 159 0.022
calcium ion transport GO:0006816 131 0.021
cellular chemical homeostasis GO:0055082 247 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
regulation of hydrolase activity GO:0051336 143 0.021
cell cell signaling GO:0007267 335 0.021
cell motility GO:0048870 202 0.021
response to transition metal nanoparticle GO:1990267 122 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
fatty acid metabolic process GO:0006631 99 0.021
secretion GO:0046903 307 0.021
immune system process GO:0002376 204 0.021
regulation of neurogenesis GO:0050767 247 0.020
response to carbohydrate GO:0009743 183 0.020
response to ethanol GO:0045471 162 0.020
g protein coupled receptor signaling pathway GO:0007186 242 0.020
carboxylic acid biosynthetic process GO:0046394 83 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
protein targeting GO:0006605 61 0.020
regulation of cellular localization GO:0060341 263 0.020
blood circulation GO:0008015 183 0.020
positive regulation of nervous system development GO:0051962 178 0.020
response to estradiol GO:0032355 164 0.020
regulation of neuron differentiation GO:0045664 208 0.019
metal ion transport GO:0030001 289 0.019
peptide biosynthetic process GO:0043043 3 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
locomotion GO:0040011 237 0.019
glutathione metabolic process GO:0006749 15 0.019
fatty acid oxidation GO:0019395 29 0.019
response to vitamin GO:0033273 131 0.019
spermatogenesis GO:0007283 99 0.019
single organism catabolic process GO:0044712 283 0.019
response to reactive oxygen species GO:0000302 120 0.019
cellular metal ion homeostasis GO:0006875 172 0.019
cellular response to lipid GO:0071396 201 0.018
cellular ion homeostasis GO:0006873 184 0.018
cofactor metabolic process GO:0051186 95 0.018
regulation of neuron death GO:1901214 115 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
circulatory system development GO:0072359 134 0.018
axis specification GO:0009798 4 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
response to organophosphorus GO:0046683 102 0.018
regulation of protein modification process GO:0031399 194 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
neuron projection development GO:0031175 273 0.018
neuron apoptotic process GO:0051402 88 0.018
transcription dna templated GO:0006351 377 0.018
positive regulation of gene expression GO:0010628 244 0.018
catabolic process GO:0009056 351 0.018
lipid catabolic process GO:0016042 46 0.018
cellular cation homeostasis GO:0030003 180 0.017
response to corticosterone GO:0051412 40 0.017
negative regulation of catalytic activity GO:0043086 103 0.017
organ regeneration GO:0031100 101 0.017
response to other organism GO:0051707 220 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
cytoplasmic transport GO:0016482 115 0.017
cellular protein localization GO:0034613 122 0.017
angiogenesis GO:0001525 53 0.017
regeneration GO:0031099 163 0.017
regulation of ion transport GO:0043269 245 0.017
intracellular protein transport GO:0006886 79 0.017
negative regulation of phosphorus metabolic process GO:0010563 80 0.017
positive regulation of monooxygenase activity GO:0032770 5 0.017
positive regulation of signaling GO:0023056 270 0.016
developmental growth GO:0048589 100 0.016
positive regulation of transport GO:0051050 245 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
dna metabolic process GO:0006259 96 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
inorganic cation transmembrane transport GO:0098662 202 0.016
gastrulation GO:0007369 2 0.016
negative regulation of cell cycle phase transition GO:1901988 4 0.016
response to glucose GO:0009749 136 0.016
regulation of transmembrane transport GO:0034762 122 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
divalent inorganic cation transport GO:0072511 134 0.016
synaptic transmission GO:0007268 235 0.016
response to radiation GO:0009314 137 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
blood vessel development GO:0001568 69 0.015
reactive nitrogen species metabolic process GO:2001057 1 0.015
regulation of cell projection organization GO:0031344 175 0.015
ion homeostasis GO:0050801 212 0.015
regulation of signal transduction GO:0009966 318 0.015
behavior GO:0007610 205 0.015
regulation of oxidoreductase activity GO:0051341 11 0.015
response to growth factor GO:0070848 189 0.015
negative regulation of phosphate metabolic process GO:0045936 80 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
dephosphorylation GO:0016311 98 0.015
regulation of synaptic transmission GO:0050804 141 0.015
regulation of system process GO:0044057 208 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
multicellular organism growth GO:0035264 1 0.015
forebrain development GO:0030900 98 0.015
cell cycle checkpoint GO:0000075 2 0.015
tissue development GO:0009888 252 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
calcium ion homeostasis GO:0055074 162 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
chromosome segregation GO:0007059 2 0.014
single organism organelle organization GO:1902589 180 0.014
pteridine containing compound metabolic process GO:0042558 14 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.014
glycerophospholipid metabolic process GO:0006650 47 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
positive regulation of cell development GO:0010720 176 0.014
negative regulation of signaling GO:0023057 157 0.014
regulation of cytokine production GO:0001817 56 0.014
positive regulation of oxidoreductase activity GO:0051353 7 0.014
maintenance of location GO:0051235 17 0.014
regulation of cell development GO:0060284 263 0.014
single organism membrane organization GO:0044802 74 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
localization of cell GO:0051674 202 0.014
anion transport GO:0006820 178 0.014
response to mineralocorticoid GO:0051385 49 0.014
muscle system process GO:0003012 115 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.014
neutral lipid metabolic process GO:0006638 21 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
regulation of membrane potential GO:0042391 110 0.013
carboxylic acid transport GO:0046942 115 0.013
response to testosterone GO:0033574 55 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
growth GO:0040007 165 0.013
protein autophosphorylation GO:0046777 66 0.013
reproductive system development GO:0061458 128 0.013
neuron death GO:0070997 127 0.013
protein heterooligomerization GO:0051291 89 0.013
cellular response to alcohol GO:0097306 87 0.013
phosphatidic acid biosynthetic process GO:0006654 1 0.013
phospholipid biosynthetic process GO:0008654 29 0.013
positive regulation of mitochondrion organization GO:0010822 4 0.013
cellular response to steroid hormone stimulus GO:0071383 93 0.013
organic acid transport GO:0015849 116 0.013
negative regulation of innate immune response GO:0045824 4 0.013
cell cycle GO:0007049 101 0.013
cellular response to peptide GO:1901653 133 0.013
response to monosaccharide GO:0034284 159 0.013
ribose phosphate biosynthetic process GO:0046390 87 0.013
negative regulation of peptidase activity GO:0010466 38 0.013
triglyceride metabolic process GO:0006641 21 0.012
positive regulation of neuron apoptotic process GO:0043525 33 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
cell growth GO:0016049 104 0.012
negative regulation of protein phosphorylation GO:0001933 44 0.012
male gamete generation GO:0048232 99 0.012
nucleotide metabolic process GO:0009117 279 0.012
epithelium development GO:0060429 96 0.012
peptide metabolic process GO:0006518 32 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
rhythmic process GO:0048511 156 0.012
negative regulation of neuron death GO:1901215 69 0.012
organic substance catabolic process GO:1901575 316 0.012
ras protein signal transduction GO:0007265 29 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
blood vessel morphogenesis GO:0048514 58 0.012
liver development GO:0001889 90 0.012
regulation of establishment of protein localization GO:0070201 69 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
regulation of secretion by cell GO:1903530 208 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
regulation of neuron projection development GO:0010975 161 0.012
cellular modified amino acid biosynthetic process GO:0042398 18 0.012
negative regulation of transport GO:0051051 136 0.012
establishment of protein localization to organelle GO:0072594 44 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
regulation of response to external stimulus GO:0032101 106 0.012
negative regulation of cell development GO:0010721 82 0.012
regulation of cell motility GO:2000145 131 0.012
calcium ion transmembrane transport GO:0070588 70 0.012
respiratory system development GO:0060541 45 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
vesicle mediated transport GO:0016192 181 0.012
protein maturation GO:0051604 68 0.012
endochondral bone growth GO:0003416 3 0.012
regulation of blood circulation GO:1903522 110 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
purine ribonucleotide biosynthetic process GO:0009152 81 0.012
vasculature development GO:0001944 70 0.012
regulation of calcium ion transport GO:0051924 77 0.012
positive regulation of protein metabolic process GO:0051247 178 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
urogenital system development GO:0001655 78 0.011
lipid storage GO:0019915 1 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
regulation of catabolic process GO:0009894 113 0.011
protein processing GO:0016485 68 0.011
mitotic cell cycle checkpoint GO:0007093 1 0.011
amide transport GO:0042886 105 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
muscle contraction GO:0006936 88 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
hepaticobiliary system development GO:0061008 90 0.011
positive regulation of lipid metabolic process GO:0045834 33 0.011
cellular response to tumor necrosis factor GO:0071356 46 0.011
response to amino acid GO:0043200 75 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
regulation of protein maturation GO:1903317 50 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
heart process GO:0003015 57 0.011
gland development GO:0048732 155 0.011
organic hydroxy compound transport GO:0015850 77 0.011
nucleocytoplasmic transport GO:0006913 48 0.011
regulation of secretion GO:0051046 224 0.011
immune response GO:0006955 104 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
muscle structure development GO:0061061 87 0.010
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
membrane organization GO:0061024 94 0.010
neuron development GO:0048666 286 0.010
regulation of protein localization GO:0032880 81 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010
response to wounding GO:0009611 254 0.010
negative regulation of protein modification process GO:0031400 52 0.010
negative regulation of cell communication GO:0010648 158 0.010
female pregnancy GO:0007565 122 0.010
heart contraction GO:0060047 57 0.010
response to hexose GO:0009746 144 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.010
lipid localization GO:0010876 62 0.010
heterocycle catabolic process GO:0046700 167 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.010
cellular response to oxidative stress GO:0034599 76 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
positive regulation of cytokine production GO:0001819 42 0.010
hormone transport GO:0009914 121 0.010
purine containing compound biosynthetic process GO:0072522 85 0.010
mitotic cell cycle process GO:1903047 35 0.010
small molecule catabolic process GO:0044282 59 0.010
negative regulation of proteolysis GO:0045861 41 0.010

Tmem120a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.014
disease of cellular proliferation DOID:14566 0 0.013
nervous system disease DOID:863 0 0.013
disease of anatomical entity DOID:7 0 0.013
central nervous system disease DOID:331 0 0.012
cancer DOID:162 0 0.010