Rattus norvegicus

0 known processes

Srgap2

SLIT-ROBO Rho GTPase activating protein 2

(Aliases: RGD1566016,MGC188551)

Srgap2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of phosphate metabolic process GO:0019220 349 0.092
Human Mouse Rat
regulation of signal transduction GO:0009966 318 0.069
Human Mouse Rat
carboxylic acid metabolic process GO:0019752 289 0.066
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.066
Human Mouse Rat
organic acid metabolic process GO:0006082 292 0.064
cellular component assembly GO:0022607 360 0.058
Human Mouse
regulation of molecular function GO:0065009 398 0.054
Human Mouse Rat
apoptotic process GO:0006915 381 0.052
positive regulation of programmed cell death GO:0043068 157 0.050
organelle organization GO:0006996 266 0.049
Mouse
regulation of apoptotic process GO:0042981 335 0.048
cellular amino acid metabolic process GO:0006520 107 0.047
regulation of phosphorylation GO:0042325 248 0.044
intracellular signal transduction GO:0035556 314 0.043
single organism catabolic process GO:0044712 283 0.043
Human Mouse Rat
oxoacid metabolic process GO:0043436 290 0.042
cellular component biogenesis GO:0044085 368 0.042
Human Mouse
positive regulation of cell death GO:0010942 184 0.042
regulation of cellular ketone metabolic process GO:0010565 27 0.041
positive regulation of signaling GO:0023056 270 0.040
programmed cell death GO:0012501 392 0.039
regulation of cellular protein metabolic process GO:0032268 267 0.039
organic cyclic compound catabolic process GO:1901361 175 0.038
Human Mouse Rat
carbohydrate derivative catabolic process GO:1901136 147 0.038
Human Mouse Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.038
Human Mouse Rat
rna biosynthetic process GO:0032774 380 0.038
cell type specific apoptotic process GO:0097285 134 0.037
positive regulation of developmental process GO:0051094 283 0.036
glycosyl compound metabolic process GO:1901657 182 0.036
Human Mouse Rat
protein phosphorylation GO:0006468 345 0.036
rna metabolic process GO:0016070 406 0.036
cell projection organization GO:0030030 302 0.035
Human Mouse Rat
regulation of programmed cell death GO:0043067 341 0.035
regulation of intracellular signal transduction GO:1902531 218 0.035
Human Mouse Rat
nucleoside phosphate metabolic process GO:0006753 283 0.034
Human Mouse Rat
ribonucleotide metabolic process GO:0009259 231 0.034
Human Mouse Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.034
Human Mouse Rat
regulation of rna metabolic process GO:0051252 391 0.033
positive regulation of response to stimulus GO:0048584 285 0.033
carbohydrate derivative metabolic process GO:1901135 346 0.033
Human Mouse Rat
neuron differentiation GO:0030182 368 0.033
Human Mouse Rat
ribonucleoside catabolic process GO:0042454 126 0.032
Human Mouse Rat
positive regulation of cell communication GO:0010647 271 0.032
ribonucleotide catabolic process GO:0009261 136 0.032
Human Mouse Rat
cellular ketone metabolic process GO:0042180 51 0.032
regulation of neuron differentiation GO:0045664 208 0.032
Rat
positive regulation of molecular function GO:0044093 230 0.031
Human Mouse Rat
transcription dna templated GO:0006351 377 0.031
response to wounding GO:0009611 254 0.031
nucleoside metabolic process GO:0009116 179 0.031
Human Mouse Rat
cellular component morphogenesis GO:0032989 155 0.030
Human Mouse Rat
single organism organelle organization GO:1902589 180 0.030
Mouse
response to nutrient levels GO:0031667 370 0.030
regulation of cellular component organization GO:0051128 368 0.030
Rat
nucleoside triphosphate metabolic process GO:0009141 144 0.030
Human Mouse Rat
regulation of protein metabolic process GO:0051246 289 0.030
cell morphogenesis involved in differentiation GO:0000904 119 0.029
Human Rat
positive regulation of multicellular organismal process GO:0051240 387 0.029
ras protein signal transduction GO:0007265 29 0.029
ribose phosphate metabolic process GO:0019693 235 0.029
Human Mouse Rat
response to inorganic substance GO:0010035 377 0.029
small gtpase mediated signal transduction GO:0007264 36 0.029
purine containing compound catabolic process GO:0072523 138 0.028
Human Mouse Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.028
cellular component movement GO:0006928 248 0.028
Human Mouse Rat
nucleic acid templated transcription GO:0097659 379 0.028
protein complex assembly GO:0006461 263 0.028
regulation of hydrolase activity GO:0051336 143 0.027
Human Mouse Rat
ribonucleoside metabolic process GO:0009119 174 0.027
Human Mouse Rat
regulation of catalytic activity GO:0050790 304 0.027
Human Mouse Rat
organophosphate metabolic process GO:0019637 370 0.027
Human Mouse Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.027
Human Mouse Rat
glycosyl compound catabolic process GO:1901658 126 0.027
Human Mouse Rat
catabolic process GO:0009056 351 0.027
Human Mouse Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
negative regulation of metabolic process GO:0009892 331 0.026
regulation of anatomical structure size GO:0090066 135 0.026
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
macromolecular complex assembly GO:0065003 273 0.026
organonitrogen compound catabolic process GO:1901565 179 0.026
Human Mouse Rat
negative regulation of cell death GO:0060548 229 0.026
central nervous system development GO:0007417 311 0.026
Mouse
cellular amine metabolic process GO:0044106 38 0.025
positive regulation of catalytic activity GO:0043085 184 0.025
Human Mouse Rat
regulation of cell development GO:0060284 263 0.025
Human Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.025
Human Mouse Rat
aromatic compound catabolic process GO:0019439 168 0.025
Human Mouse Rat
positive regulation of protein metabolic process GO:0051247 178 0.025
regulation of system process GO:0044057 208 0.025
purine nucleotide metabolic process GO:0006163 229 0.024
Human Mouse Rat
single organism reproductive process GO:0044702 297 0.024
cation transport GO:0006812 382 0.024
growth GO:0040007 165 0.024
Rat
nucleotide catabolic process GO:0009166 139 0.024
Human Mouse Rat
purine nucleotide catabolic process GO:0006195 136 0.024
Human Mouse Rat
protein complex biogenesis GO:0070271 263 0.024
regulation of multicellular organismal development GO:2000026 376 0.024
Human Rat
protein complex subunit organization GO:0071822 302 0.023
positive regulation of apoptotic process GO:0043065 154 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
Human Mouse Rat
regulation of cell projection organization GO:0031344 175 0.023
Rat
wound healing GO:0042060 122 0.023
amine metabolic process GO:0009308 38 0.023
regulation of protein phosphorylation GO:0001932 183 0.023
organophosphate catabolic process GO:0046434 148 0.022
Human Mouse Rat
regulation of cellular amine metabolic process GO:0033238 8 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
response to hypoxia GO:0001666 231 0.022
purine ribonucleotide catabolic process GO:0009154 136 0.022
Human Mouse Rat
cellular response to oxygen containing compound GO:1901701 386 0.022
vesicle mediated transport GO:0016192 181 0.022
purine containing compound metabolic process GO:0072521 253 0.022
Human Mouse Rat
nucleoside catabolic process GO:0009164 126 0.022
Human Mouse Rat
regulation of cell proliferation GO:0042127 359 0.021
homeostatic process GO:0042592 331 0.021
positive regulation of hydrolase activity GO:0051345 86 0.021
Human Mouse Rat
nucleobase containing compound catabolic process GO:0034655 152 0.021
Human Mouse Rat
response to oxygen levels GO:0070482 265 0.021
metal ion transport GO:0030001 289 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
cellular catabolic process GO:0044248 295 0.021
Human Mouse Rat
locomotion GO:0040011 237 0.021
Human Mouse Rat
regulation of rna biosynthetic process GO:2001141 381 0.021
brain development GO:0007420 247 0.021
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
positive regulation of gene expression GO:0010628 244 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
Human Mouse Rat
positive regulation of biosynthetic process GO:0009891 319 0.020
nucleotide metabolic process GO:0009117 279 0.020
Human Mouse Rat
response to extracellular stimulus GO:0009991 380 0.020
neuron projection development GO:0031175 273 0.020
Human Mouse Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
regulation of transcription dna templated GO:0006355 374 0.020
g protein coupled receptor signaling pathway GO:0007186 242 0.020
tissue development GO:0009888 252 0.020
regulation of cellular localization GO:0060341 263 0.020
ion transmembrane transport GO:0034220 365 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
Human Mouse Rat
response to estrogen GO:0043627 232 0.020
protein oligomerization GO:0051259 191 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
regulation of membrane potential GO:0042391 110 0.019
heterocycle catabolic process GO:0046700 167 0.019
Human Mouse Rat
regulation of neurogenesis GO:0050767 247 0.019
Human Rat
cellular response to stress GO:0033554 269 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.019
nucleoside triphosphate catabolic process GO:0009143 123 0.019
Human Mouse Rat
multi organism reproductive process GO:0044703 262 0.019
localization of cell GO:0051674 202 0.019
Human Mouse Rat
neurological system process GO:0050877 219 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
biological adhesion GO:0022610 110 0.018
Human
cellular nitrogen compound catabolic process GO:0044270 163 0.018
Human Mouse Rat
protein localization GO:0008104 191 0.018
establishment of protein localization GO:0045184 141 0.018
nitrogen compound transport GO:0071705 229 0.018
regulation of neuron projection development GO:0010975 161 0.018
Rat
actin filament based process GO:0030029 86 0.018
Human
anatomical structure morphogenesis GO:0009653 298 0.018
Human Mouse Rat
positive regulation of cell differentiation GO:0045597 217 0.018
cellular lipid metabolic process GO:0044255 208 0.018
ion homeostasis GO:0050801 212 0.018
secretion GO:0046903 307 0.018
response to decreased oxygen levels GO:0036293 237 0.018
developmental growth GO:0048589 100 0.018
Rat
negative regulation of apoptotic process GO:0043066 181 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
regulation of secretion GO:0051046 224 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
single organism biosynthetic process GO:0044711 342 0.017
secretion by cell GO:0032940 248 0.017
cellular homeostasis GO:0019725 252 0.017
cell motility GO:0048870 202 0.017
Human Mouse Rat
head development GO:0060322 247 0.017
Mouse
circulatory system process GO:0003013 183 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
purine ribonucleoside catabolic process GO:0046130 124 0.017
Human Mouse Rat
positive regulation of transcription dna templated GO:0045893 197 0.017
nucleoside phosphate catabolic process GO:1901292 140 0.017
Human Mouse Rat
transcription from rna polymerase ii promoter GO:0006366 252 0.017
response to bacterium GO:0009617 200 0.017
neuron development GO:0048666 286 0.017
Human Mouse Rat
positive regulation of cell development GO:0010720 176 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
Human Rat
lipid metabolic process GO:0006629 283 0.016
cell morphogenesis GO:0000902 142 0.016
Human Mouse Rat
response to peptide GO:1901652 292 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
Human Mouse Rat
ribonucleoside triphosphate catabolic process GO:0009203 122 0.016
Human Mouse Rat
positive regulation of signal transduction GO:0009967 175 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
Human Mouse Rat
regulation of protein modification process GO:0031399 194 0.016
negative regulation of molecular function GO:0044092 133 0.016
single organism cellular localization GO:1902580 102 0.016
reproductive process GO:0022414 372 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
regulation of blood vessel size GO:0050880 89 0.016
positive regulation of nucleotide metabolic process GO:0045981 91 0.016
Human Mouse Rat
chemical homeostasis GO:0048878 292 0.016
muscle system process GO:0003012 115 0.016
response to acid chemical GO:0001101 222 0.016
negative regulation of gene expression GO:0010629 199 0.015
cellular macromolecule localization GO:0070727 122 0.015
intracellular transport GO:0046907 185 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
cell projection morphogenesis GO:0048858 123 0.015
Mouse Rat
multicellular organism reproduction GO:0032504 233 0.015
regulation of cell differentiation GO:0045595 320 0.015
Human Rat
transmembrane transport GO:0055085 412 0.015
divalent metal ion transport GO:0070838 132 0.015
response to ketone GO:1901654 182 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
Human Mouse Rat
organic substance catabolic process GO:1901575 316 0.014
Human Mouse Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
response to peptide hormone GO:0043434 278 0.014
membrane organization GO:0061024 94 0.014
divalent inorganic cation transport GO:0072511 134 0.014
gastrulation GO:0007369 2 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
Human Mouse Rat
regulation of neuron death GO:1901214 115 0.014
regulation of nervous system development GO:0051960 264 0.014
Human Rat
positive regulation of phosphorylation GO:0042327 177 0.014
regulation of response to stress GO:0080134 126 0.014
cytoskeleton organization GO:0007010 111 0.014
Mouse
peptidyl amino acid modification GO:0018193 126 0.014
leukocyte activation GO:0045321 76 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
Human Mouse Rat
cellular ion homeostasis GO:0006873 184 0.014
cellular chemical homeostasis GO:0055082 247 0.014
cell activation GO:0001775 97 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
regulation of vesicle mediated transport GO:0060627 81 0.014
reproduction GO:0000003 245 0.014
muscle structure development GO:0061061 87 0.014
inflammatory response GO:0006954 150 0.014
cell cell signaling GO:0007267 335 0.014
carbohydrate metabolic process GO:0005975 130 0.013
response to metal ion GO:0010038 253 0.013
behavior GO:0007610 205 0.013
protein homooligomerization GO:0051260 91 0.013
macromolecule localization GO:0033036 252 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
cellular response to steroid hormone stimulus GO:0071383 93 0.013
immune system process GO:0002376 204 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
Rat
cell migration GO:0016477 197 0.013
Human Mouse Rat
protein heterooligomerization GO:0051291 89 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
response to nutrient GO:0007584 248 0.013
calcium ion transport GO:0006816 131 0.013
myeloid leukocyte activation GO:0002274 36 0.013
response to estradiol GO:0032355 164 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
Human Mouse Rat
oxidation reduction process GO:0055114 304 0.013
maintenance of location GO:0051235 17 0.013
cellular protein localization GO:0034613 122 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
response to mechanical stimulus GO:0009612 134 0.013
regulation of body fluid levels GO:0050878 90 0.013
anterior posterior pattern specification GO:0009952 1 0.013
positive regulation of protein modification process GO:0031401 142 0.013
cell cycle GO:0007049 101 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
Human Mouse Rat
monocarboxylic acid metabolic process GO:0032787 152 0.012
rho protein signal transduction GO:0007266 11 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
Rat
regulation of transferase activity GO:0051338 123 0.012
sexual reproduction GO:0019953 148 0.012
regulation of tube size GO:0035150 89 0.012
platelet aggregation GO:0070527 4 0.012
negative regulation of cell communication GO:0010648 158 0.012
negative regulation of signaling GO:0023057 157 0.012
positive regulation of transport GO:0051050 245 0.012
response to oxidative stress GO:0006979 186 0.012
gland development GO:0048732 155 0.012
axon development GO:0061564 96 0.012
Rat
regulation of kinase activity GO:0043549 117 0.012
cellular response to lipid GO:0071396 201 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
Human Mouse Rat
positive regulation of neurogenesis GO:0050769 165 0.012
regulation of cellular component movement GO:0051270 150 0.012
Human Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
negative regulation of transport GO:0051051 136 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
gtp catabolic process GO:0006184 71 0.012
Human Mouse Rat
positive regulation of nervous system development GO:0051962 178 0.012
protein transport GO:0015031 132 0.012
neuron projection morphogenesis GO:0048812 122 0.011
Mouse Rat
vascular process in circulatory system GO:0003018 96 0.011
cardiac chamber development GO:0003205 1 0.011
hormone transport GO:0009914 121 0.011
positive regulation of nucleoside metabolic process GO:0045979 55 0.011
Human Mouse Rat
gamete generation GO:0007276 124 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
cytoplasmic transport GO:0016482 115 0.011
axis specification GO:0009798 4 0.011
regulation of growth GO:0040008 105 0.011
Rat
regulation of secretion by cell GO:1903530 208 0.011
tube development GO:0035295 89 0.011
heart morphogenesis GO:0003007 3 0.011
neuron death GO:0070997 127 0.011
response to toxic substance GO:0009636 133 0.011
single organism behavior GO:0044708 130 0.011
salivary gland development GO:0007431 3 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
regulation of fat cell differentiation GO:0045598 3 0.011
response to cytokine GO:0034097 215 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
Human Mouse Rat
gtp metabolic process GO:0046039 72 0.011
Human Mouse Rat
single organism intracellular transport GO:1902582 166 0.011
dna metabolic process GO:0006259 96 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
single organism membrane organization GO:0044802 74 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
regulation of nucleoside metabolic process GO:0009118 66 0.011
Human Mouse Rat
developmental process involved in reproduction GO:0003006 159 0.011
lipid storage GO:0019915 1 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
coagulation GO:0050817 28 0.011
regulation of immune system process GO:0002682 123 0.010
signal release GO:0023061 145 0.010
regulation of hormone levels GO:0010817 187 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
Human Mouse Rat
response to carbohydrate GO:0009743 183 0.010
defense response GO:0006952 194 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
regulation of cell migration GO:0030334 128 0.010
Human Rat
regulation of muscle system process GO:0090257 79 0.010
sequestering of calcium ion GO:0051208 8 0.010
male gamete generation GO:0048232 99 0.010
positive regulation of cellular catabolic process GO:0031331 71 0.010
Human Mouse Rat
regulation of actin filament based process GO:0032970 42 0.010
circulatory system development GO:0072359 134 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
rna localization GO:0006403 4 0.010
cellular cation homeostasis GO:0030003 180 0.010
negative regulation of catalytic activity GO:0043086 103 0.010

Srgap2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.017
disease of anatomical entity DOID:7 0 0.017
musculoskeletal system disease DOID:17 0 0.013
disease of metabolism DOID:0014667 0 0.012