Rattus norvegicus

14 known processes

C9

complement component 9

C9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
extracellular matrix constituent secretion GO:0070278 4 0.536
response to peptide hormone GO:0043434 278 0.479
regulation of serine type endopeptidase activity GO:1900003 1 0.307
cellular response to hormone stimulus GO:0032870 247 0.292
positive regulation of extracellular matrix constituent secretion GO:0003331 2 0.231
cellular response to stress GO:0033554 269 0.222
negative regulation of protein metabolic process GO:0051248 114 0.190
single organism biosynthetic process GO:0044711 342 0.186
renal sodium excretion GO:0035812 20 0.180
regulation of serine type peptidase activity GO:1902571 1 0.177
protein maturation GO:0051604 68 0.166
protein localization GO:0008104 191 0.164
response to inorganic substance GO:0010035 377 0.163
multi organism reproductive process GO:0044703 262 0.160
transmission of nerve impulse GO:0019226 42 0.154
response to peptide GO:1901652 292 0.153
inflammatory response GO:0006954 150 0.147
regeneration GO:0031099 163 0.146
defense response GO:0006952 194 0.141
response to organophosphorus GO:0046683 102 0.137
regulation of cellular localization GO:0060341 263 0.134
response to wounding GO:0009611 254 0.131
macromolecular complex subunit organization GO:0043933 339 0.129
response to metal ion GO:0010038 253 0.127
response to radiation GO:0009314 137 0.122
regulation of cellular protein metabolic process GO:0032268 267 0.120
multi multicellular organism process GO:0044706 138 0.118
response to ketone GO:1901654 182 0.113
proteolysis GO:0006508 175 0.111
hemostasis GO:0007599 26 0.110
response to nutrient GO:0007584 248 0.110
positive regulation of response to stimulus GO:0048584 285 0.109
organic substance catabolic process GO:1901575 316 0.108
negative regulation of cellular protein metabolic process GO:0032269 106 0.107
response to vitamin GO:0033273 131 0.098
cellular lipid metabolic process GO:0044255 208 0.097
negative regulation of metabolic process GO:0009892 331 0.097
cellular component biogenesis GO:0044085 368 0.094
homeostatic process GO:0042592 331 0.093
response to acid chemical GO:0001101 222 0.091
response to glucocorticoid GO:0051384 223 0.090
reproductive process GO:0022414 372 0.088
regulation of body fluid levels GO:0050878 90 0.087
response to lead ion GO:0010288 33 0.085
cellular response to corticosteroid stimulus GO:0071384 69 0.083
cellular response to steroid hormone stimulus GO:0071383 93 0.080
angiotensin mediated drinking behavior GO:0003051 2 0.079
multicellular organismal reproductive process GO:0048609 233 0.079
response to molecule of bacterial origin GO:0002237 194 0.079
lipid metabolic process GO:0006629 283 0.078
multicellular organism reproduction GO:0032504 233 0.077
cellular response to oxygen containing compound GO:1901701 386 0.076
response to nutrient levels GO:0031667 370 0.076
cellular catabolic process GO:0044248 295 0.075
regulation of signal transduction GO:0009966 318 0.074
negative regulation of cellular metabolic process GO:0031324 281 0.073
response to vitamin b6 GO:0034516 1 0.073
negative regulation of serine type endopeptidase activity GO:1900004 1 0.073
cellular response to peptide hormone stimulus GO:0071375 120 0.072
multicellular organismal signaling GO:0035637 44 0.071
regulation of protein maturation GO:1903317 50 0.070
response to extracellular stimulus GO:0009991 380 0.069
macromolecule localization GO:0033036 252 0.069
regulation of catalytic activity GO:0050790 304 0.068
behavior GO:0007610 205 0.068
response to muscle activity involved in regulation of muscle adaptation GO:0014873 2 0.068
negative regulation of protein processing GO:0010955 47 0.067
programmed cell death GO:0012501 392 0.067
Rat
regulation of molecular function GO:0065009 398 0.066
regulation of programmed cell death GO:0043067 341 0.064
Rat
response to reactive oxygen species GO:0000302 120 0.064
catabolic process GO:0009056 351 0.064
urea cycle GO:0000050 5 0.063
response to oxidative stress GO:0006979 186 0.062
response to bacterium GO:0009617 200 0.062
negative regulation of macromolecule metabolic process GO:0010605 260 0.061
regulation of protein metabolic process GO:0051246 289 0.060
response to corticosteroid GO:0031960 235 0.059
b cell mediated immunity GO:0019724 4 0.059
cellular response to lipid GO:0071396 201 0.059
protein transport GO:0015031 132 0.059
carbohydrate derivative metabolic process GO:1901135 346 0.058
negative regulation of molecular function GO:0044092 133 0.058
wound healing GO:0042060 122 0.057
regulation of protein processing GO:0070613 50 0.057
negative regulation of peptidase activity GO:0010466 38 0.057
anion transport GO:0006820 178 0.057
regulation of response to external stimulus GO:0032101 106 0.057
oxoacid metabolic process GO:0043436 290 0.056
intracellular signal transduction GO:0035556 314 0.056
liver development GO:0001889 90 0.055
neurological system process GO:0050877 219 0.055
regulation of phosphate metabolic process GO:0019220 349 0.055
aging GO:0007568 241 0.054
immunoglobulin mediated immune response GO:0016064 4 0.053
negative regulation of protein maturation GO:1903318 47 0.053
regulation of apoptotic process GO:0042981 335 0.053
Rat
cytokine secretion GO:0050663 15 0.052
negative regulation of serine type peptidase activity GO:1902572 1 0.052
coagulation GO:0050817 28 0.052
macromolecular complex assembly GO:0065003 273 0.051
protein processing GO:0016485 68 0.051
regulation of extracellular matrix constituent secretion GO:0003330 2 0.049
regulation of cell proliferation GO:0042127 359 0.049
single organism catabolic process GO:0044712 283 0.048
organic acid metabolic process GO:0006082 292 0.047
positive regulation of multicellular organismal process GO:0051240 387 0.047
regulation of norepinephrine secretion GO:0014061 15 0.047
regulation of hydrolase activity GO:0051336 143 0.047
negative regulation of multicellular organismal process GO:0051241 203 0.046
organic hydroxy compound metabolic process GO:1901615 115 0.045
carboxylic acid metabolic process GO:0019752 289 0.045
response to biotic stimulus GO:0009607 226 0.045
response to oxygen levels GO:0070482 265 0.045
single organism reproductive process GO:0044702 297 0.044
gland development GO:0048732 155 0.044
regulation of cellular amine metabolic process GO:0033238 8 0.044
immune system process GO:0002376 204 0.042
hepatocyte proliferation GO:0072574 3 0.041
positive regulation of signaling GO:0023056 270 0.041
growth GO:0040007 165 0.041
regulation of cellular component organization GO:0051128 368 0.041
amine metabolic process GO:0009308 38 0.041
blood coagulation GO:0007596 26 0.040
cellular response to endogenous stimulus GO:0071495 377 0.040
anatomical structure morphogenesis GO:0009653 298 0.040
ion homeostasis GO:0050801 212 0.040
circulatory system development GO:0072359 134 0.040
reproduction GO:0000003 245 0.040
brain renin angiotensin system GO:0002035 3 0.040
regulation of multicellular organismal development GO:2000026 376 0.040
cellular amino acid metabolic process GO:0006520 107 0.039
regulation of cellular ketone metabolic process GO:0010565 27 0.039
response to estrogen GO:0043627 232 0.039
cellular amine metabolic process GO:0044106 38 0.038
regulation of response to wounding GO:1903034 69 0.038
response to activity GO:0014823 73 0.038
apoptotic process GO:0006915 381 0.038
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.037
cellular response to fluid shear stress GO:0071498 4 0.037
cellular ion homeostasis GO:0006873 184 0.037
positive regulation of cell proliferation GO:0008284 249 0.037
negative regulation of gene expression GO:0010629 199 0.036
negative regulation of response to stimulus GO:0048585 155 0.036
response to transition metal nanoparticle GO:1990267 122 0.036
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.036
response to insulin GO:0032868 133 0.036
positive regulation of extracellular matrix organization GO:1903055 4 0.036
female pregnancy GO:0007565 122 0.036
regulation of membrane potential GO:0042391 110 0.035
purine ribonucleotide metabolic process GO:0009150 227 0.035
protein complex subunit organization GO:0071822 302 0.034
immune response GO:0006955 104 0.034
organonitrogen compound catabolic process GO:1901565 179 0.034
excretion GO:0007588 24 0.034
liver morphogenesis GO:0072576 3 0.034
cellular response to nitrogen compound GO:1901699 210 0.033
cellular ketone metabolic process GO:0042180 51 0.033
intracellular transport GO:0046907 185 0.033
positive regulation of molecular function GO:0044093 230 0.033
gamete generation GO:0007276 124 0.032
cell activation GO:0001775 97 0.032
axon ensheathment GO:0008366 40 0.031
response to vitamin a GO:0033189 36 0.031
response to lipopolysaccharide GO:0032496 191 0.031
spermatogenesis GO:0007283 99 0.031
negative regulation of apoptotic process GO:0043066 181 0.031
response to triglyceride GO:0034014 3 0.031
negative regulation of developmental process GO:0051093 125 0.031
monocarboxylic acid metabolic process GO:0032787 152 0.030
negative regulation of endopeptidase activity GO:0010951 36 0.030
protein phosphorylation GO:0006468 345 0.030
protein complex assembly GO:0006461 263 0.030
response to camp GO:0051591 91 0.030
cellular chemical homeostasis GO:0055082 247 0.029
nucleobase containing small molecule metabolic process GO:0055086 316 0.029
tissue remodeling GO:0048771 40 0.029
regulation of protein modification process GO:0031399 194 0.028
secretion by cell GO:0032940 248 0.028
secretion GO:0046903 307 0.028
response to cytokine GO:0034097 215 0.028
cellular response to peptide GO:1901653 133 0.028
acute inflammatory response GO:0002526 58 0.028
cellular homeostasis GO:0019725 252 0.027
cellular component assembly GO:0022607 360 0.027
neuronal action potential GO:0019228 35 0.027
ribonucleoside catabolic process GO:0042454 126 0.027
forebrain development GO:0030900 98 0.027
negative regulation of proteolysis GO:0045861 41 0.027
regulation of phosphorylation GO:0042325 248 0.027
regulation of protein phosphorylation GO:0001932 183 0.027
unsaturated fatty acid metabolic process GO:0033559 39 0.026
fatty acid metabolic process GO:0006631 99 0.026
cellular macromolecule localization GO:0070727 122 0.026
amine transport GO:0015837 57 0.026
regulation of system process GO:0044057 208 0.026
regulation of cell differentiation GO:0045595 320 0.026
positive regulation of protein phosphorylation GO:0001934 135 0.026
aromatic amino acid family catabolic process GO:0009074 7 0.026
male gamete generation GO:0048232 99 0.026
response to axon injury GO:0048678 59 0.025
cellular metal ion homeostasis GO:0006875 172 0.025
cellular cation homeostasis GO:0030003 180 0.025
action potential GO:0001508 54 0.025
protein complex biogenesis GO:0070271 263 0.025
carboxylic acid transport GO:0046942 115 0.025
response to estradiol GO:0032355 164 0.025
regulation of growth GO:0040008 105 0.025
monocarboxylic acid transport GO:0015718 52 0.024
response to hypoxia GO:0001666 231 0.024
negative regulation of cell communication GO:0010648 158 0.024
lipid localization GO:0010876 62 0.024
response to retinoic acid GO:0032526 63 0.024
regulation of catabolic process GO:0009894 113 0.023
regulation of synaptic plasticity GO:0048167 70 0.023
establishment of protein localization GO:0045184 141 0.023
positive regulation of catalytic activity GO:0043085 184 0.023
positive regulation of blood coagulation GO:0030194 4 0.023
response to chromate GO:0046687 3 0.023
blood circulation GO:0008015 183 0.023
regulation of renal sodium excretion GO:0035813 20 0.023
organic anion transport GO:0015711 132 0.023
cellular response to organonitrogen compound GO:0071417 197 0.023
positive regulation of programmed cell death GO:0043068 157 0.023
Rat
positive regulation of cell communication GO:0010647 271 0.023
positive regulation of cell death GO:0010942 184 0.022
Rat
cellular response to glucocorticoid stimulus GO:0071385 68 0.022
cation homeostasis GO:0055080 195 0.022
purine containing compound metabolic process GO:0072521 253 0.021
single organism cellular localization GO:1902580 102 0.021
regulation of intracellular signal transduction GO:1902531 218 0.021
single organism intracellular transport GO:1902582 166 0.021
calcium ion homeostasis GO:0055074 162 0.021
regulation of neurogenesis GO:0050767 247 0.021
chemical homeostasis GO:0048878 292 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
cellular sodium ion homeostasis GO:0006883 4 0.021
norepinephrine secretion GO:0048243 16 0.021
regulation of response to stress GO:0080134 126 0.020
regulation of excretion GO:0044062 21 0.020
epithelial cell proliferation GO:0050673 54 0.020
organophosphate metabolic process GO:0019637 370 0.020
central nervous system development GO:0007417 311 0.020
ensheathment of neurons GO:0007272 40 0.020
circulatory system process GO:0003013 183 0.020
regulation of reactive oxygen species metabolic process GO:2000377 26 0.020
regulation of peptide transport GO:0090087 87 0.020
positive regulation of transport GO:0051050 245 0.020
rna biosynthetic process GO:0032774 380 0.019
regulation of amine transport GO:0051952 54 0.019
icosanoid metabolic process GO:0006690 38 0.019
positive regulation of homeostatic process GO:0032846 49 0.019
carboxylic acid biosynthetic process GO:0046394 83 0.019
developmental growth GO:0048589 100 0.019
positive regulation of secretion by cell GO:1903532 128 0.019
synaptic transmission GO:0007268 235 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
negative regulation of cell proliferation GO:0008285 119 0.018
regulation of neurological system process GO:0031644 43 0.018
regulation of blood circulation GO:1903522 110 0.018
response to hexose GO:0009746 144 0.018
muscle contraction GO:0006936 88 0.018
positive regulation of signal transduction GO:0009967 175 0.018
regulation of immune system process GO:0002682 123 0.018
metal ion transport GO:0030001 289 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
regulation of proteolysis GO:0030162 66 0.018
metal ion homeostasis GO:0055065 186 0.018
naphthalene containing compound metabolic process GO:0090420 2 0.017
renin angiotensin regulation of aldosterone production GO:0002018 3 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
regulation of secretion GO:0051046 224 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.017
regulation of rna biosynthetic process GO:2001141 381 0.017
sexual reproduction GO:0019953 148 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
regulation of ion homeostasis GO:2000021 63 0.017
protein homooligomerization GO:0051260 91 0.016
regulation of establishment of protein localization GO:0070201 69 0.016
vasculature development GO:0001944 70 0.016
regulation of peptidase activity GO:0052547 55 0.016
cell growth GO:0016049 104 0.016
myelination GO:0042552 39 0.016
neuron projection development GO:0031175 273 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
organ regeneration GO:0031100 101 0.016
cellular response to external stimulus GO:0071496 118 0.016
cholesterol homeostasis GO:0042632 3 0.016
neuron development GO:0048666 286 0.016
endocrine system development GO:0035270 30 0.015
neuron differentiation GO:0030182 368 0.015
jak stat cascade GO:0007259 26 0.015
cellular protein localization GO:0034613 122 0.015
regulation of homeostatic process GO:0032844 101 0.015
cell projection organization GO:0030030 302 0.015
regulation of cell growth GO:0001558 85 0.015
mapk cascade GO:0000165 140 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
defense response to gram negative bacterium GO:0050829 3 0.015
cytokine production GO:0001816 61 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.014
positive regulation of blood circulation GO:1903524 65 0.014
single organism behavior GO:0044708 130 0.014
response to platinum ion GO:0070541 4 0.014
organic acid biosynthetic process GO:0016053 83 0.014
protein activation cascade GO:0072376 12 0.014
muscle system process GO:0003012 115 0.014
catecholamine transport GO:0051937 37 0.014
positive regulation of protein modification process GO:0031401 142 0.014
carboxylic acid catabolic process GO:0046395 49 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.014
regulation of ion transport GO:0043269 245 0.014
oxidation reduction process GO:0055114 304 0.014
nucleotide metabolic process GO:0009117 279 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
cell adhesion GO:0007155 110 0.014
negative regulation of calcium ion import GO:0090281 2 0.014
response to other organism GO:0051707 220 0.014
regulation of calcium ion transport GO:0051924 77 0.014
response to methanol GO:0033986 1 0.014
negative regulation of cellular amide metabolic process GO:0034249 1 0.014
response to light stimulus GO:0009416 52 0.013
protein localization to nucleus GO:0034504 39 0.013
protein targeting GO:0006605 61 0.013
positive regulation of tyrosine phosphorylation of stat1 protein GO:0042511 1 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
innate immune response GO:0045087 35 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
regulation of cellular response to stress GO:0080135 49 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
positive regulation of secretion GO:0051047 140 0.013
peptidyl amino acid modification GO:0018193 126 0.013
hepaticobiliary system development GO:0061008 90 0.013
transmembrane transport GO:0055085 412 0.013
biological adhesion GO:0022610 110 0.013
regulation of epithelial cell proliferation GO:0050678 49 0.013
response to monosaccharide GO:0034284 159 0.013
cytoplasmic transport GO:0016482 115 0.013
small molecule biosynthetic process GO:0044283 124 0.013
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.013
carbohydrate homeostasis GO:0033500 75 0.013
regulation of hormone levels GO:0010817 187 0.013
nitrogen cycle metabolic process GO:0071941 5 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
protein oligomerization GO:0051259 191 0.013
negative regulation of catalytic activity GO:0043086 103 0.012
response to ethanol GO:0045471 162 0.012
response to external biotic stimulus GO:0043207 221 0.012
response to fluid shear stress GO:0034405 16 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
cellular response to molecule of bacterial origin GO:0071219 56 0.012
positive regulation of peptide hormone secretion GO:0090277 50 0.012
cellular response to reactive oxygen species GO:0034614 55 0.012
nuclear transport GO:0051169 49 0.012
stress activated protein kinase signaling cascade GO:0031098 37 0.012
response to glucose GO:0009749 136 0.012
rhythmic process GO:0048511 156 0.012
negative regulation of signaling GO:0023057 157 0.012
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
vasoconstriction GO:0042310 54 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
blood vessel development GO:0001568 69 0.012
positive regulation of renal sodium excretion GO:0035815 10 0.012
urea metabolic process GO:0019627 5 0.012
negative regulation of innate immune response GO:0045824 4 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
regulation of mapk cascade GO:0043408 116 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
negative regulation of cell death GO:0060548 229 0.011
cytolysis GO:0019835 4 0.011
Rat
carbohydrate derivative catabolic process GO:1901136 147 0.011
sodium ion homeostasis GO:0055078 23 0.011
nucleotide catabolic process GO:0009166 139 0.011
neuron neuron synaptic transmission GO:0007270 60 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
ion transmembrane transport GO:0034220 365 0.011
cellular response to glucose stimulus GO:0071333 65 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
response to ddt GO:0046680 1 0.011
lipid biosynthetic process GO:0008610 128 0.011
response to temperature stimulus GO:0009266 94 0.011
regulation of muscle system process GO:0090257 79 0.011
long chain fatty acid metabolic process GO:0001676 32 0.011
cardiovascular system development GO:0072358 134 0.011
regulation of defense response GO:0031347 68 0.011
catenin import into nucleus GO:0035411 1 0.011
kidney development GO:0001822 67 0.010
response to testosterone GO:0033574 55 0.010
regulation of blood pressure GO:0008217 83 0.010
cellular response to retinoic acid GO:0071300 27 0.010
epithelial cell proliferation involved in liver morphogenesis GO:0072575 3 0.010
gastrulation GO:0007369 2 0.010
organelle organization GO:0006996 266 0.010
calcium ion import GO:0070509 22 0.010
response to decreased oxygen levels GO:0036293 237 0.010
negative regulation of humoral immune response GO:0002921 4 0.010
regulation of metal ion transport GO:0010959 118 0.010
tissue development GO:0009888 252 0.010
regulation of cell development GO:0060284 263 0.010
naphthalene metabolic process GO:0018931 2 0.010
response to fatty acid GO:0070542 65 0.010
cellular response to luteinizing hormone stimulus GO:0071373 5 0.010
linoleic acid metabolic process GO:0043651 4 0.010

C9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.036
inherited metabolic disorder DOID:655 0 0.036
immune system disease DOID:2914 0 0.023
disease of anatomical entity DOID:7 0 0.023
blood coagulation disease DOID:1247 0 0.023
inherited blood coagulation disease DOID:2214 0 0.023
hematopoietic system disease DOID:74 0 0.023
familial hyperlipidemia DOID:1168 0 0.013
lipid metabolism disorder DOID:3146 0 0.013