Rattus norvegicus

43 known processes

C2

complement component 2

C2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
complement activation GO:0006956 11 0.654
activation of immune response GO:0002253 26 0.614
immune response GO:0006955 104 0.306
immune system process GO:0002376 204 0.239
positive regulation of response to stimulus GO:0048584 285 0.234
regulation of immune system process GO:0002682 123 0.189
positive regulation of immune response GO:0050778 42 0.165
immune effector process GO:0002252 53 0.158
regulation of multicellular organismal development GO:2000026 376 0.129
regulation of protein metabolic process GO:0051246 289 0.116
response to nutrient levels GO:0031667 370 0.097
organic acid metabolic process GO:0006082 292 0.092
regulation of immune response GO:0050776 55 0.081
protein processing GO:0016485 68 0.069
cytolysis GO:0019835 4 0.068
response to lipopolysaccharide GO:0032496 191 0.064
inflammatory response GO:0006954 150 0.063
regulation of cellular protein metabolic process GO:0032268 267 0.063
immunoglobulin mediated immune response GO:0016064 4 0.063
response to camp GO:0051591 91 0.061
response to other organism GO:0051707 220 0.055
negative regulation of gene expression GO:0010629 199 0.053
acute inflammatory response GO:0002526 58 0.053
response to glucocorticoid GO:0051384 223 0.052
organonitrogen compound catabolic process GO:1901565 179 0.050
positive regulation of immune system process GO:0002684 90 0.049
protein activation cascade GO:0072376 12 0.049
oxoacid metabolic process GO:0043436 290 0.048
programmed cell death GO:0012501 392 0.047
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
homeostatic process GO:0042592 331 0.039
response to corticosteroid GO:0031960 235 0.039
humoral immune response GO:0006959 12 0.038
negative regulation of multicellular organismal process GO:0051241 203 0.038
cellular amine metabolic process GO:0044106 38 0.037
response to wounding GO:0009611 254 0.036
regulation of hydrolase activity GO:0051336 143 0.036
positive regulation of developmental process GO:0051094 283 0.035
chemosensory behavior GO:0007635 2 0.035
response to estradiol GO:0032355 164 0.033
apoptotic process GO:0006915 381 0.033
negative regulation of innate immune response GO:0045824 4 0.033
regulation of catalytic activity GO:0050790 304 0.033
cellular response to stress GO:0033554 269 0.033
proteolysis GO:0006508 175 0.032
wound healing GO:0042060 122 0.032
positive regulation of cell differentiation GO:0045597 217 0.032
regulation of phosphorylation GO:0042325 248 0.031
regulation of cell development GO:0060284 263 0.030
t cell tolerance induction GO:0002517 3 0.030
protein maturation GO:0051604 68 0.030
cellular amino acid metabolic process GO:0006520 107 0.029
regulation of protein maturation GO:1903317 50 0.029
catabolic process GO:0009056 351 0.028
positive regulation of protein metabolic process GO:0051247 178 0.027
negative regulation of molecular function GO:0044092 133 0.027
amine metabolic process GO:0009308 38 0.026
positive regulation of hemostasis GO:1900048 4 0.026
lipid localization GO:0010876 62 0.025
nucleic acid templated transcription GO:0097659 379 0.024
lipid storage GO:0019915 1 0.024
regulation of signal transduction GO:0009966 318 0.024
negative regulation of metabolic process GO:0009892 331 0.024
regulation of neurogenesis GO:0050767 247 0.024
regulation of neuron differentiation GO:0045664 208 0.023
regulation of transcription dna templated GO:0006355 374 0.023
protein phosphorylation GO:0006468 345 0.023
antigen processing and presentation GO:0019882 2 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
response to extracellular stimulus GO:0009991 380 0.023
carboxylic acid metabolic process GO:0019752 289 0.023
response to biotic stimulus GO:0009607 226 0.023
regulation of programmed cell death GO:0043067 341 0.023
regulation of rna metabolic process GO:0051252 391 0.023
localization of cell GO:0051674 202 0.023
organic substance catabolic process GO:1901575 316 0.022
positive regulation of blood coagulation GO:0030194 4 0.022
regulation of nucleic acid templated transcription GO:1903506 380 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
negative regulation of peptidase activity GO:0010466 38 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
regulation of neuron projection development GO:0010975 161 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
defense response GO:0006952 194 0.022
leukocyte mediated immunity GO:0002443 28 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.021
cellular response to lipid GO:0071396 201 0.021
regulation of protein processing GO:0070613 50 0.021
regulation of nervous system development GO:0051960 264 0.021
acute phase response GO:0006953 20 0.021
coagulation GO:0050817 28 0.021
negative regulation of developmental process GO:0051093 125 0.021
response to ketone GO:1901654 182 0.021
reproductive process GO:0022414 372 0.021
cellular response to oxygen containing compound GO:1901701 386 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
positive regulation of gene expression GO:0010628 244 0.020
cell growth GO:0016049 104 0.020
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
negative regulation of catalytic activity GO:0043086 103 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
monocarboxylic acid metabolic process GO:0032787 152 0.019
nucleotide metabolic process GO:0009117 279 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
response to external biotic stimulus GO:0043207 221 0.019
rna biosynthetic process GO:0032774 380 0.019
cellular catabolic process GO:0044248 295 0.019
positive regulation of signaling GO:0023056 270 0.018
hemostasis GO:0007599 26 0.018
reproduction GO:0000003 245 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
positive regulation of tolerance induction GO:0002645 1 0.018
response to nutrient GO:0007584 248 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
regulation of cell differentiation GO:0045595 320 0.018
ras protein signal transduction GO:0007265 29 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
response to inorganic substance GO:0010035 377 0.017
cellular ketone metabolic process GO:0042180 51 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
positive regulation of neuron projection development GO:0010976 99 0.017
regulation of protein modification process GO:0031399 194 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
reactive nitrogen species metabolic process GO:2001057 1 0.017
neuron development GO:0048666 286 0.017
response to cytokine GO:0034097 215 0.016
multi multicellular organism process GO:0044706 138 0.016
response to peptide hormone GO:0043434 278 0.016
negative regulation of endopeptidase activity GO:0010951 36 0.016
cell projection organization GO:0030030 302 0.016
rhythmic process GO:0048511 156 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
positive regulation of nervous system development GO:0051962 178 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
response to molecule of bacterial origin GO:0002237 194 0.015
positive regulation of cell death GO:0010942 184 0.015
positive regulation of molecular function GO:0044093 230 0.015
cellular amide metabolic process GO:0043603 44 0.015
gland development GO:0048732 155 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
regulation of growth GO:0040008 105 0.015
neuron projection development GO:0031175 273 0.015
regulation of molecular function GO:0065009 398 0.015
regulation of defense response GO:0031347 68 0.015
regulation of developmental growth GO:0048638 45 0.014
metal ion transport GO:0030001 289 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
peptidyl tyrosine phosphorylation GO:0018108 72 0.014
nucleoside catabolic process GO:0009164 126 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
positive regulation of growth GO:0045927 55 0.014
regulation of proteolysis GO:0030162 66 0.014
growth GO:0040007 165 0.014
response to metal ion GO:0010038 253 0.014
organophosphate metabolic process GO:0019637 370 0.014
positive regulation of neuron differentiation GO:0045666 126 0.013
response to purine containing compound GO:0014074 126 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
regulation of response to wounding GO:1903034 69 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
regulation of cell projection organization GO:0031344 175 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
monocarboxylic acid biosynthetic process GO:0072330 48 0.013
regeneration GO:0031099 163 0.013
gtp catabolic process GO:0006184 71 0.013
immune system development GO:0002520 41 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
multi organism reproductive process GO:0044703 262 0.013
b cell mediated immunity GO:0019724 4 0.013
heterocycle catabolic process GO:0046700 167 0.012
chemical homeostasis GO:0048878 292 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
multicellular organism reproduction GO:0032504 233 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
maintenance of location GO:0051235 17 0.012
protein complex assembly GO:0006461 263 0.012
lipid biosynthetic process GO:0008610 128 0.012
response to decreased oxygen levels GO:0036293 237 0.012
nucleoside metabolic process GO:0009116 179 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
regulation of response to stress GO:0080134 126 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
organelle organization GO:0006996 266 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
dendrite development GO:0016358 72 0.012
protein complex subunit organization GO:0071822 302 0.012
cellular response to glucocorticoid stimulus GO:0071385 68 0.012
regulation of axon extension GO:0030516 24 0.012
intracellular signal transduction GO:0035556 314 0.012
neuron differentiation GO:0030182 368 0.012
tolerance induction dependent upon immune response GO:0002461 2 0.012
negative regulation of proteolysis GO:0045861 41 0.012
rho protein signal transduction GO:0007266 11 0.012
regulation of rna biosynthetic process GO:2001141 381 0.012
negative regulation of protein maturation GO:1903318 47 0.012
rna metabolic process GO:0016070 406 0.012
angiogenesis GO:0001525 53 0.012
positive regulation of developmental growth GO:0048639 29 0.011
urogenital system development GO:0001655 78 0.011
cellular modified amino acid metabolic process GO:0006575 61 0.011
regulation of system process GO:0044057 208 0.011
regulation of inflammatory response GO:0050727 48 0.011
regulation of cell growth GO:0001558 85 0.011
positive regulation of protein modification process GO:0031401 142 0.011
jak stat cascade GO:0007259 26 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
regulation of peptidase activity GO:0052547 55 0.011
cellular component assembly GO:0022607 360 0.011
circadian rhythm GO:0007623 88 0.011
blood coagulation GO:0007596 26 0.011
positive regulation of t cell mediated cytotoxicity GO:0001916 4 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
response to dexamethasone GO:0071548 49 0.010
positive regulation of cell communication GO:0010647 271 0.010
regulation of cell migration GO:0030334 128 0.010
endocytosis GO:0006897 84 0.010
cellular sodium ion homeostasis GO:0006883 4 0.010
multicellular organismal reproductive process GO:0048609 233 0.010
regulation of immune effector process GO:0002697 32 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
positive regulation of cellular component organization GO:0051130 200 0.010
regulation of hormone levels GO:0010817 187 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
developmental growth GO:0048589 100 0.010
macromolecular complex subunit organization GO:0043933 339 0.010
peptidyl amino acid modification GO:0018193 126 0.010

C2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.068
inherited metabolic disorder DOID:655 0 0.068