Rattus norvegicus

20 known processes

C7

complement component 7

C7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to corticosteroid GO:0031960 235 0.157
response to lipopolysaccharide GO:0032496 191 0.101
kidney development GO:0001822 67 0.096
response to biotic stimulus GO:0009607 226 0.091
positive regulation of response to stimulus GO:0048584 285 0.085
protein complex subunit organization GO:0071822 302 0.071
protein complex assembly GO:0006461 263 0.070
cellular component biogenesis GO:0044085 368 0.067
innate immune response GO:0045087 35 0.067
response to hexose GO:0009746 144 0.067
response to glucose GO:0009749 136 0.066
urogenital system development GO:0001655 78 0.060
camera type eye development GO:0043010 48 0.059
response to inorganic substance GO:0010035 377 0.059
response to molecule of bacterial origin GO:0002237 194 0.058
cellular component assembly GO:0022607 360 0.057
response to other organism GO:0051707 220 0.054
renal system development GO:0072001 67 0.054
cellular homeostasis GO:0019725 252 0.052
cellular response to cytokine stimulus GO:0071345 127 0.051
protein complex biogenesis GO:0070271 263 0.049
response to extracellular stimulus GO:0009991 380 0.049
rhythmic process GO:0048511 156 0.048
Rat
macromolecular complex subunit organization GO:0043933 339 0.046
negative regulation of innate immune response GO:0045824 4 0.045
positive regulation of cellular biosynthetic process GO:0031328 295 0.043
carbohydrate derivative metabolic process GO:1901135 346 0.043
regulation of immune system process GO:0002682 123 0.043
cellular chemical homeostasis GO:0055082 247 0.043
ras protein signal transduction GO:0007265 29 0.042
metal ion transport GO:0030001 289 0.041
cellular response to hormone stimulus GO:0032870 247 0.040
positive regulation of biosynthetic process GO:0009891 319 0.039
positive regulation of immune response GO:0050778 42 0.038
regulation of cell differentiation GO:0045595 320 0.038
protein oligomerization GO:0051259 191 0.038
reproductive system development GO:0061458 128 0.038
response to nutrient levels GO:0031667 370 0.036
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.036
response to monosaccharide GO:0034284 159 0.035
positive regulation of immune system process GO:0002684 90 0.035
response to hypoxia GO:0001666 231 0.034
regulation of multicellular organismal development GO:2000026 376 0.034
aging GO:0007568 241 0.034
vesicle mediated transport GO:0016192 181 0.034
homeostatic process GO:0042592 331 0.033
response to glucocorticoid GO:0051384 223 0.033
response to ketone GO:1901654 182 0.033
leukocyte cell cell adhesion GO:0007159 4 0.033
cellular response to lipid GO:0071396 201 0.033
response to nutrient GO:0007584 248 0.032
reproductive structure development GO:0048608 128 0.032
cation transport GO:0006812 382 0.032
oxidation reduction process GO:0055114 304 0.032
defense response GO:0006952 194 0.031
organic acid metabolic process GO:0006082 292 0.031
cellular cation homeostasis GO:0030003 180 0.031
cation transmembrane transport GO:0098655 263 0.031
tissue development GO:0009888 252 0.030
response to cytokine GO:0034097 215 0.030
response to mechanical stimulus GO:0009612 134 0.030
regulation of cell projection organization GO:0031344 175 0.029
positive regulation of developmental process GO:0051094 283 0.029
small gtpase mediated signal transduction GO:0007264 36 0.029
cellular response to oxygen containing compound GO:1901701 386 0.029
chemical homeostasis GO:0048878 292 0.029
reproductive process GO:0022414 372 0.029
rna biosynthetic process GO:0032774 380 0.028
regulation of locomotion GO:0040012 148 0.028
intracellular signal transduction GO:0035556 314 0.028
macromolecular complex assembly GO:0065003 273 0.027
apoptotic process GO:0006915 381 0.027
Rat
regulation of immune response GO:0050776 55 0.027
multicellular organism reproduction GO:0032504 233 0.026
calcium ion homeostasis GO:0055074 162 0.026
oxoacid metabolic process GO:0043436 290 0.026
ion homeostasis GO:0050801 212 0.026
transmembrane transport GO:0055085 412 0.026
eye development GO:0001654 50 0.025
cellular response to organic cyclic compound GO:0071407 202 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
ion transmembrane transport GO:0034220 365 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
response to estrogen GO:0043627 232 0.024
leukocyte activation GO:0045321 76 0.024
muscle structure development GO:0061061 87 0.024
biological adhesion GO:0022610 110 0.024
circadian rhythm GO:0007623 88 0.024
Rat
response to wounding GO:0009611 254 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.024
head development GO:0060322 247 0.024
inorganic cation transmembrane transport GO:0098662 202 0.023
developmental process involved in reproduction GO:0003006 159 0.023
glomerulus vasculature development GO:0072012 6 0.023
cellular response to steroid hormone stimulus GO:0071383 93 0.023
reactive oxygen species metabolic process GO:0072593 37 0.022
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.022
response to external biotic stimulus GO:0043207 221 0.022
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.022
immune system process GO:0002376 204 0.022
cellular ion homeostasis GO:0006873 184 0.022
positive regulation of gene expression GO:0010628 244 0.021
regulation of molecular function GO:0065009 398 0.021
reproduction GO:0000003 245 0.021
neurological system process GO:0050877 219 0.021
response to carbohydrate GO:0009743 183 0.021
complement activation GO:0006956 11 0.020
response to decreased oxygen levels GO:0036293 237 0.020
response to metal ion GO:0010038 253 0.020
eye morphogenesis GO:0048592 4 0.020
regulation of transcription dna templated GO:0006355 374 0.020
protein homooligomerization GO:0051260 91 0.020
cellular amine metabolic process GO:0044106 38 0.020
programmed cell death GO:0012501 392 0.020
Rat
regulation of cell development GO:0060284 263 0.019
positive regulation of molecular function GO:0044093 230 0.019
skeletal muscle tissue development GO:0007519 31 0.019
calcium ion transport GO:0006816 131 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
immune response GO:0006955 104 0.019
cellular response to external stimulus GO:0071496 118 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
cellular response to stress GO:0033554 269 0.019
inorganic ion transmembrane transport GO:0098660 229 0.019
cellular component movement GO:0006928 248 0.019
regulation of nervous system development GO:0051960 264 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
response to ethanol GO:0045471 162 0.018
Rat
response to acid chemical GO:0001101 222 0.018
rna metabolic process GO:0016070 406 0.018
cation homeostasis GO:0055080 195 0.018
positive regulation of cell development GO:0010720 176 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
organic substance catabolic process GO:1901575 316 0.017
alcohol metabolic process GO:0006066 77 0.017
anion transport GO:0006820 178 0.017
cellular response to glucocorticoid stimulus GO:0071385 68 0.017
muscle organ development GO:0007517 50 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
cellular response to extracellular stimulus GO:0031668 73 0.017
glomerulus development GO:0032835 10 0.017
regulation of catalytic activity GO:0050790 304 0.017
sex differentiation GO:0007548 113 0.016
positive regulation of transport GO:0051050 245 0.016
rho protein signal transduction GO:0007266 11 0.016
cellular catabolic process GO:0044248 295 0.016
regulation of innate immune response GO:0045088 15 0.016
developmental growth involved in morphogenesis GO:0060560 33 0.016
positive regulation of cell communication GO:0010647 271 0.016
regulation of body fluid levels GO:0050878 90 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
odontogenesis GO:0042476 32 0.016
regulation of rna metabolic process GO:0051252 391 0.016
regulation of response to external stimulus GO:0032101 106 0.016
response to bacterium GO:0009617 200 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
response to oxygen levels GO:0070482 265 0.015
muscle tissue development GO:0060537 58 0.015
response to growth factor GO:0070848 189 0.015
single organism reproductive process GO:0044702 297 0.015
organophosphate metabolic process GO:0019637 370 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
sequestering of metal ion GO:0051238 9 0.015
metal ion homeostasis GO:0055065 186 0.015
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.015
divalent metal ion transport GO:0070838 132 0.015
cellular response to endogenous stimulus GO:0071495 377 0.015
myeloid leukocyte activation GO:0002274 36 0.015
regulation of ion transport GO:0043269 245 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
regulation of programmed cell death GO:0043067 341 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
peptidyl amino acid modification GO:0018193 126 0.014
regulation of response to stress GO:0080134 126 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
single organism catabolic process GO:0044712 283 0.014
regulation of defense response GO:0031347 68 0.014
cell projection organization GO:0030030 302 0.014
negative regulation of immune response to tumor cell GO:0002838 2 0.014
regulation of apoptotic process GO:0042981 335 0.014
neuron projection development GO:0031175 273 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
amine metabolic process GO:0009308 38 0.014
regulation of signal transduction GO:0009966 318 0.014
regeneration GO:0031099 163 0.014
cellular response to abiotic stimulus GO:0071214 85 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
cell activation GO:0001775 97 0.014
catabolic process GO:0009056 351 0.014
muscle contraction GO:0006936 88 0.014
multi organism reproductive process GO:0044703 262 0.014
sulfur compound metabolic process GO:0006790 70 0.014
multi multicellular organism process GO:0044706 138 0.014
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.014
growth GO:0040007 165 0.013
sequestering of calcium ion GO:0051208 8 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
brain development GO:0007420 247 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
regulation of phosphorus metabolic process GO:0051174 349 0.013
inflammatory response GO:0006954 150 0.013
skeletal muscle organ development GO:0060538 33 0.013
carboxylic acid metabolic process GO:0019752 289 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
development of primary sexual characteristics GO:0045137 107 0.013
negative regulation of apoptotic process GO:0043066 181 0.012
immune effector process GO:0002252 53 0.012
organelle organization GO:0006996 266 0.012
regulation of immune response to tumor cell GO:0002837 3 0.012
behavior GO:0007610 205 0.012
positive regulation of rna metabolic process GO:0051254 203 0.012
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.012
regulation of cellular component organization GO:0051128 368 0.012
protein heterooligomerization GO:0051291 89 0.012
nucleotide metabolic process GO:0009117 279 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
cellular response to nutrient levels GO:0031669 60 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
single organism organelle organization GO:1902589 180 0.012
lipid metabolic process GO:0006629 283 0.012
regulation of muscle contraction GO:0006937 53 0.012
regulation of leukocyte activation GO:0002694 45 0.012
negative regulation of cell death GO:0060548 229 0.012
cellular response to ketone GO:1901655 51 0.012
regulation of protein metabolic process GO:0051246 289 0.012
regulation of rna biosynthetic process GO:2001141 381 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
neuron development GO:0048666 286 0.012
kidney vasculature development GO:0061440 6 0.011
positive regulation of leukocyte activation GO:0002696 30 0.011
multicellular organismal homeostasis GO:0048871 49 0.011
extracellular matrix organization GO:0030198 13 0.011
cellular response to mechanical stimulus GO:0071260 48 0.011
calcium ion transport into cytosol GO:0060402 38 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
positive regulation of cell activation GO:0050867 34 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
sensory perception of pain GO:0019233 73 0.011
macromolecule localization GO:0033036 252 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
response to peptide GO:1901652 292 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
renal system vasculature development GO:0061437 6 0.011
regulation of hormone levels GO:0010817 187 0.011
single organism cell adhesion GO:0098602 46 0.011
single organism behavior GO:0044708 130 0.011
positive regulation of ion transport GO:0043270 94 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
single organismal cell cell adhesion GO:0016337 42 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
regulation of neuron projection development GO:0010975 161 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
positive regulation of signaling GO:0023056 270 0.011
peptide cross linking GO:0018149 1 0.011
response to oxidative stress GO:0006979 186 0.010
regulation of membrane potential GO:0042391 110 0.010
cell type specific apoptotic process GO:0097285 134 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
response to alkaloid GO:0043279 132 0.010
proteoglycan metabolic process GO:0006029 3 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
cytoplasmic transport GO:0016482 115 0.010
epithelium development GO:0060429 96 0.010
positive regulation of cellular component biogenesis GO:0044089 55 0.010
negative regulation of biomineral tissue development GO:0070168 2 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
positive regulation of cell differentiation GO:0045597 217 0.010
smooth muscle contraction GO:0006939 37 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
positive regulation of innate immune response GO:0045089 11 0.010

C7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.026
cancer DOID:162 0 0.020
organ system cancer DOID:0050686 0 0.020
myopathy DOID:423 0 0.013
muscular disease DOID:0080000 0 0.013
muscular dystrophy DOID:9884 0 0.013
disease of anatomical entity DOID:7 0 0.013
musculoskeletal system disease DOID:17 0 0.013
muscle tissue disease DOID:66 0 0.013
nervous system disease DOID:863 0 0.013
gastrointestinal system cancer DOID:3119 0 0.012