Rattus norvegicus

42 known processes

Dab1

disabled homolog 1 (Drosophila)

Dab1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell cell signaling GO:0007267 335 0.163
Rat Fly
negative regulation of metabolic process GO:0009892 331 0.083
Rat
positive regulation of rna metabolic process GO:0051254 203 0.081
regulation of rna metabolic process GO:0051252 391 0.081
regulation of nucleic acid templated transcription GO:1903506 380 0.071
regulation of rna biosynthetic process GO:2001141 381 0.070
positive regulation of gene expression GO:0010628 244 0.069
protein phosphorylation GO:0006468 345 0.065
Mouse Rat
rna metabolic process GO:0016070 406 0.060
negative regulation of cellular metabolic process GO:0031324 281 0.060
Rat
single organism biosynthetic process GO:0044711 342 0.059
Rat
regulation of secretion by cell GO:1903530 208 0.058
Rat
oxoacid metabolic process GO:0043436 290 0.057
transcription dna templated GO:0006351 377 0.057
regulation of transcription dna templated GO:0006355 374 0.055
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.055
rna biosynthetic process GO:0032774 380 0.055
behavior GO:0007610 205 0.054
Mouse
signal release GO:0023061 145 0.054
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.053
lipid metabolic process GO:0006629 283 0.052
Rat
secretion by cell GO:0032940 248 0.050
Rat
regulation of protein metabolic process GO:0051246 289 0.050
Mouse Rat
secretion GO:0046903 307 0.049
Rat
neuron differentiation GO:0030182 368 0.047
Mouse Rat Fly
regulation of cellular protein metabolic process GO:0032268 267 0.043
Mouse Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.042
regulation of multicellular organismal development GO:2000026 376 0.042
Mouse Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.041
aging GO:0007568 241 0.041
hormone transport GO:0009914 121 0.041
Rat
nucleic acid templated transcription GO:0097659 379 0.040
negative regulation of cellular biosynthetic process GO:0031327 161 0.040
negative regulation of macromolecule metabolic process GO:0010605 260 0.038
nucleobase containing small molecule metabolic process GO:0055086 316 0.038
positive regulation of protein metabolic process GO:0051247 178 0.038
Mouse
transcription from rna polymerase ii promoter GO:0006366 252 0.038
positive regulation of nucleic acid templated transcription GO:1903508 197 0.038
positive regulation of phosphorus metabolic process GO:0010562 262 0.038
Mouse
organophosphate metabolic process GO:0019637 370 0.037
synaptic growth at neuromuscular junction GO:0051124 1 0.036
negative regulation of biosynthetic process GO:0009890 168 0.036
cellular lipid metabolic process GO:0044255 208 0.036
regulation of hormone levels GO:0010817 187 0.035
Rat
positive regulation of biosynthetic process GO:0009891 319 0.035
Rat
regulation of signal transduction GO:0009966 318 0.035
Mouse Rat
multicellular organism reproduction GO:0032504 233 0.034
head development GO:0060322 247 0.034
glutamate receptor signaling pathway GO:0007215 43 0.034
cellular component morphogenesis GO:0032989 155 0.034
Mouse Rat Fly
carboxylic acid metabolic process GO:0019752 289 0.034
developmental process involved in reproduction GO:0003006 159 0.034
negative regulation of rna biosynthetic process GO:1902679 118 0.032
regulation of synaptic transmission GO:0050804 141 0.032
regulation of cellular ketone metabolic process GO:0010565 27 0.031
Rat
brain development GO:0007420 247 0.031
negative regulation of gene expression GO:0010629 199 0.031
regulation of phosphorylation GO:0042325 248 0.030
Mouse Rat
regulation of phosphorus metabolic process GO:0051174 349 0.030
Mouse Rat
regulation of phosphate metabolic process GO:0019220 349 0.030
Mouse Rat
response to growth factor GO:0070848 189 0.029
Rat
cellular response to oxygen containing compound GO:1901701 386 0.029
negative regulation of transcription dna templated GO:0045892 116 0.029
protein complex biogenesis GO:0070271 263 0.029
Rat
negative regulation of rna metabolic process GO:0051253 123 0.029
response to wounding GO:0009611 254 0.029
cellular amine metabolic process GO:0044106 38 0.029
positive regulation of rna biosynthetic process GO:1902680 197 0.028
cellular response to stress GO:0033554 269 0.028
purine containing compound metabolic process GO:0072521 253 0.028
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.028
positive regulation of transcription dna templated GO:0045893 197 0.027
organic acid metabolic process GO:0006082 292 0.027
positive regulation of molecular function GO:0044093 230 0.027
Mouse
regulation of hormone secretion GO:0046883 106 0.027
Rat
reproductive process GO:0022414 372 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.027
negative regulation of cellular protein metabolic process GO:0032269 106 0.026
organophosphate biosynthetic process GO:0090407 143 0.025
nucleoside phosphate metabolic process GO:0006753 283 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
regulation of peptide hormone secretion GO:0090276 80 0.025
central nervous system development GO:0007417 311 0.025
neuron projection development GO:0031175 273 0.025
Mouse Rat Fly
regulation of catalytic activity GO:0050790 304 0.025
Mouse Rat
cognition GO:0050890 92 0.024
ribonucleotide metabolic process GO:0009259 231 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
negative regulation of nucleic acid templated transcription GO:1903507 117 0.024
regulation of programmed cell death GO:0043067 341 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.024
hormone secretion GO:0046879 115 0.024
Rat
regulation of protein phosphorylation GO:0001932 183 0.023
Mouse Rat
regulation of cell development GO:0060284 263 0.023
Mouse Rat
nucleotide metabolic process GO:0009117 279 0.023
single organism catabolic process GO:0044712 283 0.023
reproduction GO:0000003 245 0.023
catabolic process GO:0009056 351 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.023
Mouse
regulation of protein modification process GO:0031399 194 0.022
Mouse Rat
ribose phosphate metabolic process GO:0019693 235 0.022
multi organism reproductive process GO:0044703 262 0.022
positive regulation of signaling GO:0023056 270 0.022
Rat
regulation of neurogenesis GO:0050767 247 0.022
Mouse Rat
positive regulation of cell proliferation GO:0008284 249 0.022
amine metabolic process GO:0009308 38 0.021
regulation of neuron death GO:1901214 115 0.021
chemosensory behavior GO:0007635 2 0.021
neuron development GO:0048666 286 0.021
Mouse Rat Fly
regulation of cellular component organization GO:0051128 368 0.021
Mouse Rat
cell projection organization GO:0030030 302 0.021
Mouse Rat Fly
regulation of molecular function GO:0065009 398 0.021
Mouse Rat
single organism behavior GO:0044708 130 0.021
Mouse
intracellular signal transduction GO:0035556 314 0.021
Mouse Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
neuromuscular process GO:0050905 2 0.021
cellular ketone metabolic process GO:0042180 51 0.021
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
single organism reproductive process GO:0044702 297 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
organic hydroxy compound metabolic process GO:1901615 115 0.020
Rat
regulation of peptide secretion GO:0002791 82 0.020
regulation of cell differentiation GO:0045595 320 0.020
Mouse Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.020
inorganic cation transmembrane transport GO:0098662 202 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
Mouse Rat
peptide secretion GO:0002790 86 0.020
olfactory learning GO:0008355 1 0.020
erk1 and erk2 cascade GO:0070371 48 0.020
Rat
anatomical structure morphogenesis GO:0009653 298 0.020
Mouse Rat Fly
cell part morphogenesis GO:0032990 123 0.019
Mouse Fly
organonitrogen compound biosynthetic process GO:1901566 167 0.019
salivary gland development GO:0007431 3 0.019
purine containing compound biosynthetic process GO:0072522 85 0.019
nucleotide biosynthetic process GO:0009165 98 0.019
gonad development GO:0008406 104 0.019
sexual reproduction GO:0019953 148 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
cellular component biogenesis GO:0044085 368 0.018
Rat
locomotion GO:0040011 237 0.018
response to extracellular stimulus GO:0009991 380 0.018
gamete generation GO:0007276 124 0.018
metestrus GO:0060210 1 0.018
cell projection morphogenesis GO:0048858 123 0.018
Mouse Fly
protein complex assembly GO:0006461 263 0.018
Rat
negative regulation of cell death GO:0060548 229 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
response to nutrient levels GO:0031667 370 0.018
axon development GO:0061564 96 0.018
Mouse Fly
regulation of mapk cascade GO:0043408 116 0.018
Rat
programmed cell death GO:0012501 392 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
Rat
reproductive structure development GO:0048608 128 0.017
regulation of kinase activity GO:0043549 117 0.017
Mouse Rat
peptide hormone secretion GO:0030072 84 0.017
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.017
positive regulation of protein modification process GO:0031401 142 0.017
Mouse
response to other organism GO:0051707 220 0.017
regulation of apoptotic process GO:0042981 335 0.017
cellular component movement GO:0006928 248 0.017
negative regulation of cell communication GO:0010648 158 0.017
Mouse Rat
apoptotic process GO:0006915 381 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
regulation of nervous system development GO:0051960 264 0.016
Mouse Rat
nitrogen compound transport GO:0071705 229 0.016
regulation of anatomical structure size GO:0090066 135 0.016
purine containing compound catabolic process GO:0072523 138 0.016
positive regulation of cell development GO:0010720 176 0.016
Mouse Rat
purine ribonucleotide metabolic process GO:0009150 227 0.016
macromolecular complex assembly GO:0065003 273 0.016
Rat
response to bacterium GO:0009617 200 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
Mouse Rat
response to decreased oxygen levels GO:0036293 237 0.016
biological adhesion GO:0022610 110 0.016
Mouse Rat
response to acid chemical GO:0001101 222 0.015
heart morphogenesis GO:0003007 3 0.015
heterocycle catabolic process GO:0046700 167 0.015
olfactory behavior GO:0042048 2 0.015
regulation of secretion GO:0051046 224 0.015
Rat
ribose phosphate biosynthetic process GO:0046390 87 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
Rat
organic substance catabolic process GO:1901575 316 0.015
purine ribonucleotide biosynthetic process GO:0009152 81 0.015
regulation of protein kinase activity GO:0045859 105 0.015
Mouse Rat
ribonucleotide biosynthetic process GO:0009260 85 0.015
positive regulation of hormone secretion GO:0046887 65 0.015
Rat
cell morphogenesis involved in differentiation GO:0000904 119 0.015
Mouse Rat Fly
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
Mouse Rat
carbohydrate metabolic process GO:0005975 130 0.015
regulation of synaptic plasticity GO:0048167 70 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
Mouse
regulation of cellular localization GO:0060341 263 0.015
Rat
regulation of neuronal synaptic plasticity GO:0048168 31 0.015
regulation of neuron apoptotic process GO:0043523 83 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.015
chromosome segregation GO:0007059 2 0.014
response to inorganic substance GO:0010035 377 0.014
regulation of peptide transport GO:0090087 87 0.014
regulation of cell projection size GO:0032536 1 0.014
regulation of cell proliferation GO:0042127 359 0.014
Rat
organelle organization GO:0006996 266 0.014
Rat
purine nucleotide metabolic process GO:0006163 229 0.014
transmembrane transport GO:0055085 412 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
regulation of cytoskeleton organization GO:0051493 49 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.014
Mouse Rat
neuron apoptotic process GO:0051402 88 0.014
forebrain development GO:0030900 98 0.014
glycerolipid metabolic process GO:0046486 67 0.014
regulation of establishment of planar polarity GO:0090175 2 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
Rat
cyclic nucleotide metabolic process GO:0009187 80 0.013
neuron death GO:0070997 127 0.013
intracellular transport GO:0046907 185 0.013
sex differentiation GO:0007548 113 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
Mouse
macromolecule localization GO:0033036 252 0.013
Rat
response to ethanol GO:0045471 162 0.013
lipid modification GO:0030258 52 0.013
response to fungicide GO:0060992 20 0.013
response to external biotic stimulus GO:0043207 221 0.013
amide transport GO:0042886 105 0.013
limb morphogenesis GO:0035108 4 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
Mouse
tissue development GO:0009888 252 0.013
Fly
response to light stimulus GO:0009416 52 0.013
membrane organization GO:0061024 94 0.013
Rat
exocytosis GO:0006887 60 0.013
motor neuron axon guidance GO:0008045 1 0.013
Fly
axis specification GO:0009798 4 0.013
response to oxygen levels GO:0070482 265 0.013
gland development GO:0048732 155 0.013
positive regulation of developmental process GO:0051094 283 0.013
Mouse Rat
regulation of organelle organization GO:0033043 80 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
male gamete generation GO:0048232 99 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
gastrulation GO:0007369 2 0.013
cell cycle checkpoint GO:0000075 2 0.013
regulation of system process GO:0044057 208 0.013
Rat
cellular response to nitrogen compound GO:1901699 210 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
circulatory system development GO:0072359 134 0.013
adult locomotory behavior GO:0008344 4 0.013
Mouse
response to amino acid GO:0043200 75 0.013
microtubule organizing center organization GO:0031023 1 0.013
neuromuscular synaptic transmission GO:0007274 2 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
axonogenesis GO:0007409 71 0.012
Mouse Fly
inorganic ion transmembrane transport GO:0098660 229 0.012
embryonic appendage morphogenesis GO:0035113 4 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
anion transport GO:0006820 178 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
cellular catabolic process GO:0044248 295 0.012
regulation of cell projection organization GO:0031344 175 0.012
Mouse Rat
negative regulation of camp metabolic process GO:0030815 14 0.012
positive regulation of kinase activity GO:0033674 77 0.012
Mouse
tube development GO:0035295 89 0.012
reproductive system development GO:0061458 128 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
Rat
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.012
response to radiation GO:0009314 137 0.012
establishment of planar polarity GO:0001736 1 0.012
spermatogenesis GO:0007283 99 0.012
cell type specific apoptotic process GO:0097285 134 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
dephosphorylation GO:0016311 98 0.011
spindle organization GO:0007051 2 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
cellular protein localization GO:0034613 122 0.011
synaptic transmission GO:0007268 235 0.011
Fly
positive regulation of cell differentiation GO:0045597 217 0.011
Mouse Rat
cellular macromolecule localization GO:0070727 122 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
centrosome organization GO:0051297 1 0.011
cellular component assembly GO:0022607 360 0.011
Rat
negative regulation of molecular function GO:0044092 133 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
wound healing GO:0042060 122 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
Mouse
establishment of vesicle localization GO:0051650 31 0.011
Fly
eye morphogenesis GO:0048592 4 0.011
Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
Fly
regulation of cell morphogenesis GO:0022604 77 0.011
Mouse Rat
negative regulation of developmental process GO:0051093 125 0.011
Mouse Rat
small molecule biosynthetic process GO:0044283 124 0.011
Rat
reactive oxygen species metabolic process GO:0072593 37 0.011
cellular response to lipid GO:0071396 201 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
cytoplasmic transport GO:0016482 115 0.011
cyclic purine nucleotide metabolic process GO:0052652 62 0.011
response to axon injury GO:0048678 59 0.011
embryonic axis specification GO:0000578 1 0.011
single organism organelle organization GO:1902589 180 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
phospholipid metabolic process GO:0006644 61 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
vesicle localization GO:0051648 33 0.011
Fly
positive regulation of cell death GO:0010942 184 0.011
regulation of neurotransmitter secretion GO:0046928 19 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
macromolecular complex subunit organization GO:0043933 339 0.011
Rat
regulation of insulin secretion GO:0050796 65 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
camp metabolic process GO:0046058 63 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
Rat
limbic system development GO:0021761 38 0.011
cell morphogenesis GO:0000902 142 0.010
Mouse Rat Fly
vesicle mediated transport GO:0016192 181 0.010
Rat Fly
morphogenesis of a polarized epithelium GO:0001738 1 0.010
organ morphogenesis GO:0009887 75 0.010
Fly
salivary gland morphogenesis GO:0007435 1 0.010
maintenance of location GO:0051235 17 0.010
alcohol metabolic process GO:0006066 77 0.010
Rat
response to lipopolysaccharide GO:0032496 191 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
response to ketone GO:1901654 182 0.010
response to cocaine GO:0042220 39 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
regulation of stress activated mapk cascade GO:0032872 23 0.010
sequestering of metal ion GO:0051238 9 0.010
regulation of membrane potential GO:0042391 110 0.010
purine nucleotide biosynthetic process GO:0006164 83 0.010
regulation of dendrite development GO:0050773 59 0.010
neurological system process GO:0050877 219 0.010

Dab1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
central nervous system disease DOID:331 0 0.013
disease of metabolism DOID:0014667 0 0.012
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011