Rattus norvegicus

0 known processes

Ces4a

carboxylesterase 4A

(Aliases: Ces8,RGD1307418)

Ces4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to oxygen containing compound GO:1901701 386 0.042
organic acid metabolic process GO:0006082 292 0.042
response to nutrient levels GO:0031667 370 0.039
cellular response to endogenous stimulus GO:0071495 377 0.039
secretion by cell GO:0032940 248 0.038
oxoacid metabolic process GO:0043436 290 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
response to extracellular stimulus GO:0009991 380 0.037
neuron differentiation GO:0030182 368 0.035
Fly
carboxylic acid metabolic process GO:0019752 289 0.035
response to inorganic substance GO:0010035 377 0.034
positive regulation of multicellular organismal process GO:0051240 387 0.034
regulation of programmed cell death GO:0043067 341 0.034
rna metabolic process GO:0016070 406 0.033
response to estrogen GO:0043627 232 0.033
regulation of multicellular organismal development GO:2000026 376 0.032
programmed cell death GO:0012501 392 0.032
regulation of cell differentiation GO:0045595 320 0.032
central nervous system development GO:0007417 311 0.031
secretion GO:0046903 307 0.030
transmembrane transport GO:0055085 412 0.030
nucleic acid templated transcription GO:0097659 379 0.030
cellular amino acid metabolic process GO:0006520 107 0.030
protein complex biogenesis GO:0070271 263 0.029
regulation of cell proliferation GO:0042127 359 0.029
response to peptide GO:1901652 292 0.029
protein oligomerization GO:0051259 191 0.029
regulation of apoptotic process GO:0042981 335 0.029
negative regulation of metabolic process GO:0009892 331 0.029
regulation of rna metabolic process GO:0051252 391 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
Fly
regulation of nucleic acid templated transcription GO:1903506 380 0.029
positive regulation of biosynthetic process GO:0009891 319 0.029
macromolecular complex subunit organization GO:0043933 339 0.028
regulation of rna biosynthetic process GO:2001141 381 0.028
protein complex assembly GO:0006461 263 0.028
chemical homeostasis GO:0048878 292 0.027
cation transport GO:0006812 382 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.027
regulation of transcription dna templated GO:0006355 374 0.027
cellular component biogenesis GO:0044085 368 0.027
Fly
carbohydrate derivative metabolic process GO:1901135 346 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
cell projection organization GO:0030030 302 0.027
Fly
cellular ketone metabolic process GO:0042180 51 0.027
response to decreased oxygen levels GO:0036293 237 0.027
cellular amine metabolic process GO:0044106 38 0.027
macromolecular complex assembly GO:0065003 273 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
apoptotic process GO:0006915 381 0.026
neuron development GO:0048666 286 0.026
Fly
positive regulation of developmental process GO:0051094 283 0.026
regulation of secretion GO:0051046 224 0.026
protein complex subunit organization GO:0071822 302 0.026
amine metabolic process GO:0009308 38 0.026
cellular component assembly GO:0022607 360 0.026
Fly
regulation of cellular amine metabolic process GO:0033238 8 0.026
cellular component movement GO:0006928 248 0.026
Fly
transcription dna templated GO:0006351 377 0.026
single organism biosynthetic process GO:0044711 342 0.026
regulation of molecular function GO:0065009 398 0.026
rna biosynthetic process GO:0032774 380 0.026
response to peptide hormone GO:0043434 278 0.026
response to metal ion GO:0010038 253 0.026
regulation of signal transduction GO:0009966 318 0.026
locomotion GO:0040011 237 0.026
Fly
response to growth factor GO:0070848 189 0.026
positive regulation of cell proliferation GO:0008284 249 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.025
cellular chemical homeostasis GO:0055082 247 0.025
regulation of phosphate metabolic process GO:0019220 349 0.025
response to nutrient GO:0007584 248 0.025
regulation of cellular localization GO:0060341 263 0.025
homeostatic process GO:0042592 331 0.025
head development GO:0060322 247 0.025
protein phosphorylation GO:0006468 345 0.025
nitrogen compound transport GO:0071705 229 0.025
intracellular signal transduction GO:0035556 314 0.025
response to biotic stimulus GO:0009607 226 0.025
regulation of secretion by cell GO:1903530 208 0.025
cellular homeostasis GO:0019725 252 0.024
neuron projection development GO:0031175 273 0.024
single organism reproductive process GO:0044702 297 0.024
Fly
organophosphate metabolic process GO:0019637 370 0.024
reproductive process GO:0022414 372 0.024
Fly
regulation of catalytic activity GO:0050790 304 0.024
lipid metabolic process GO:0006629 283 0.024
Rat
reproduction GO:0000003 245 0.023
Fly
transcription from rna polymerase ii promoter GO:0006366 252 0.023
response to glucocorticoid GO:0051384 223 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
localization of cell GO:0051674 202 0.023
Fly
regulation of cell development GO:0060284 263 0.023
metal ion transport GO:0030001 289 0.023
negative regulation of cell death GO:0060548 229 0.023
neurological system process GO:0050877 219 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
positive regulation of gene expression GO:0010628 244 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
response to carbohydrate GO:0009743 183 0.023
cellular cation homeostasis GO:0030003 180 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
response to corticosteroid GO:0031960 235 0.022
regulation of neurogenesis GO:0050767 247 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
catabolic process GO:0009056 351 0.022
ion transmembrane transport GO:0034220 365 0.022
response to oxygen levels GO:0070482 265 0.022
positive regulation of response to stimulus GO:0048584 285 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
cellular response to stress GO:0033554 269 0.022
multi organism reproductive process GO:0044703 262 0.022
Fly
regulation of protein metabolic process GO:0051246 289 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
cell migration GO:0016477 197 0.022
Fly
ion homeostasis GO:0050801 212 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
response to estradiol GO:0032355 164 0.021
brain development GO:0007420 247 0.021
regulation of neuron differentiation GO:0045664 208 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
regulation of cellular component organization GO:0051128 368 0.021
cell motility GO:0048870 202 0.021
Fly
response to external biotic stimulus GO:0043207 221 0.021
response to wounding GO:0009611 254 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
organic substance catabolic process GO:1901575 316 0.021
response to cytokine GO:0034097 215 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
Fly
regulation of nervous system development GO:0051960 264 0.021
positive regulation of molecular function GO:0044093 230 0.021
cell cell signaling GO:0007267 335 0.021
cellular response to growth factor stimulus GO:0071363 162 0.021
response to hypoxia GO:0001666 231 0.021
nucleotide metabolic process GO:0009117 279 0.020
single organism catabolic process GO:0044712 283 0.020
positive regulation of signaling GO:0023056 270 0.020
response to monosaccharide GO:0034284 159 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
cellular metal ion homeostasis GO:0006875 172 0.020
regulation of hormone levels GO:0010817 187 0.020
Rat
blood circulation GO:0008015 183 0.020
response to other organism GO:0051707 220 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
circulatory system process GO:0003013 183 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
regulation of phosphorylation GO:0042325 248 0.019
cellular response to lipid GO:0071396 201 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
response to acid chemical GO:0001101 222 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
response to lipopolysaccharide GO:0032496 191 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
cation homeostasis GO:0055080 195 0.019
neuron death GO:0070997 127 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
calcium ion transport GO:0006816 131 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
cellular ion homeostasis GO:0006873 184 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
positive regulation of cell death GO:0010942 184 0.018
purine containing compound metabolic process GO:0072521 253 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
response to bacterium GO:0009617 200 0.018
response to ketone GO:1901654 182 0.018
growth GO:0040007 165 0.018
multicellular organism reproduction GO:0032504 233 0.018
Fly
response to ethanol GO:0045471 162 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
g protein coupled receptor signaling pathway GO:0007186 242 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
regeneration GO:0031099 163 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
macromolecule localization GO:0033036 252 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
regulation of neuron projection development GO:0010975 161 0.018
regulation of system process GO:0044057 208 0.018
regulation of neuron death GO:1901214 115 0.017
positive regulation of signal transduction GO:0009967 175 0.017
defense response GO:0006952 194 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
aging GO:0007568 241 0.017
calcium ion homeostasis GO:0055074 162 0.017
cation transmembrane transport GO:0098655 263 0.017
tissue development GO:0009888 252 0.017
Fly
response to hexose GO:0009746 144 0.017
positive regulation of cell communication GO:0010647 271 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
response to oxidative stress GO:0006979 186 0.017
regulation of cell projection organization GO:0031344 175 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
cellular catabolic process GO:0044248 295 0.016
response to vitamin GO:0033273 131 0.016
positive regulation of transport GO:0051050 245 0.016
gland development GO:0048732 155 0.016
behavior GO:0007610 205 0.016
positive regulation of nervous system development GO:0051962 178 0.016
negative regulation of gene expression GO:0010629 199 0.016
developmental process involved in reproduction GO:0003006 159 0.016
Fly
rhythmic process GO:0048511 156 0.016
cell type specific apoptotic process GO:0097285 134 0.016
oxidation reduction process GO:0055114 304 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
ras protein signal transduction GO:0007265 29 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
positive regulation of cell development GO:0010720 176 0.015
positive regulation of secretion GO:0051047 140 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
proteolysis GO:0006508 175 0.015
circulatory system development GO:0072359 134 0.015
Fly
response to glucose GO:0009749 136 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
regulation of hormone secretion GO:0046883 106 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
negative regulation of cell communication GO:0010648 158 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
negative regulation of signaling GO:0023057 157 0.015
metal ion homeostasis GO:0055065 186 0.015
organic anion transport GO:0015711 132 0.015
muscle system process GO:0003012 115 0.015
hormone transport GO:0009914 121 0.015
regulation of protein modification process GO:0031399 194 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
anion transport GO:0006820 178 0.015
cellular lipid metabolic process GO:0044255 208 0.014
Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.014
synaptic transmission GO:0007268 235 0.014
signal release GO:0023061 145 0.014
axis specification GO:0009798 4 0.014
heart morphogenesis GO:0003007 3 0.014
Fly
immune system process GO:0002376 204 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
amide transport GO:0042886 105 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
response to alkaloid GO:0043279 132 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
cellular response to external stimulus GO:0071496 118 0.014
protein localization GO:0008104 191 0.014
wound healing GO:0042060 122 0.014
regulation of cell migration GO:0030334 128 0.014
gamete generation GO:0007276 124 0.013
Fly
positive regulation of protein modification process GO:0031401 142 0.013
sexual reproduction GO:0019953 148 0.013
Fly
divalent inorganic cation transport GO:0072511 134 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
single organism intracellular transport GO:1902582 166 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
regulation of membrane potential GO:0042391 110 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
response to radiation GO:0009314 137 0.013
regulation of cellular component movement GO:0051270 150 0.013
regulation of ion transport GO:0043269 245 0.013
hormone secretion GO:0046879 115 0.013
regulation of anatomical structure size GO:0090066 135 0.013
Fly
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
peptide transport GO:0015833 97 0.013
cardiovascular system development GO:0072358 134 0.013
Fly
cellular response to peptide GO:1901653 133 0.013
epithelium development GO:0060429 96 0.013
Fly
organonitrogen compound biosynthetic process GO:1901566 167 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
divalent metal ion transport GO:0070838 132 0.013
regulation of immune system process GO:0002682 123 0.013
anterior posterior pattern specification GO:0009952 1 0.013
response to toxic substance GO:0009636 133 0.013
intracellular transport GO:0046907 185 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
reproductive system development GO:0061458 128 0.013
cellular component morphogenesis GO:0032989 155 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
regulation of tube size GO:0035150 89 0.013
Fly
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
organelle organization GO:0006996 266 0.013
Fly
positive regulation of neuron differentiation GO:0045666 126 0.013
regulation of locomotion GO:0040012 148 0.013
cell adhesion GO:0007155 110 0.013
Fly
establishment of protein localization GO:0045184 141 0.012
protein transport GO:0015031 132 0.012
cytoplasmic transport GO:0016482 115 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
regulation of neuron apoptotic process GO:0043523 83 0.012
multicellular organismal signaling GO:0035637 44 0.012
negative regulation of transport GO:0051051 136 0.012
reproductive structure development GO:0048608 128 0.012
neuron apoptotic process GO:0051402 88 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
negative regulation of molecular function GO:0044092 133 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
hepaticobiliary system development GO:0061008 90 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
single organism behavior GO:0044708 130 0.012
vascular process in circulatory system GO:0003018 96 0.012
nucleoside metabolic process GO:0009116 179 0.012
eye morphogenesis GO:0048592 4 0.012
regulation of mapk cascade GO:0043408 116 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
response to mechanical stimulus GO:0009612 134 0.012
multi multicellular organism process GO:0044706 138 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
regulation of hydrolase activity GO:0051336 143 0.012
mapk cascade GO:0000165 140 0.012
protein homooligomerization GO:0051260 91 0.012
negative regulation of innate immune response GO:0045824 4 0.011
regulation of blood circulation GO:1903522 110 0.011
cell projection morphogenesis GO:0048858 123 0.011
urogenital system development GO:0001655 78 0.011
salivary gland development GO:0007431 3 0.011
sex differentiation GO:0007548 113 0.011
organ regeneration GO:0031100 101 0.011
carbohydrate metabolic process GO:0005975 130 0.011
meiotic cell cycle process GO:1903046 3 0.011
Fly
female pregnancy GO:0007565 122 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
cell morphogenesis GO:0000902 142 0.011
negative regulation of neuron death GO:1901215 69 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
gastrulation GO:0007369 2 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
neuronal action potential GO:0019228 35 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
sequestering of metal ion GO:0051238 9 0.011
peptide secretion GO:0002790 86 0.011
inflammatory response GO:0006954 150 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
male gamete generation GO:0048232 99 0.011
Fly
muscle structure development GO:0061061 87 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
response to activity GO:0014823 73 0.011
gliogenesis GO:0042063 93 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
response to insulin GO:0032868 133 0.011
regulation of response to stress GO:0080134 126 0.011
transmission of nerve impulse GO:0019226 42 0.011
lipid storage GO:0019915 1 0.011
regulation of cell motility GO:2000145 131 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
peptidyl amino acid modification GO:0018193 126 0.011
spermatogenesis GO:0007283 99 0.011
Fly
action potential GO:0001508 54 0.011
maintenance of location GO:0051235 17 0.011
response to reactive oxygen species GO:0000302 120 0.011
development of primary sexual characteristics GO:0045137 107 0.011
regulation of transferase activity GO:0051338 123 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
vasculature development GO:0001944 70 0.011
regulation of peptide secretion GO:0002791 82 0.011
regulation of muscle system process GO:0090257 79 0.011
heterocycle catabolic process GO:0046700 167 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
regulation of growth GO:0040008 105 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
regulation of peptide transport GO:0090087 87 0.010
gonad development GO:0008406 104 0.010
negative regulation of developmental process GO:0051093 125 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
neuron projection morphogenesis GO:0048812 122 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
positive regulation of cellular component movement GO:0051272 102 0.010
cellular response to glucocorticoid stimulus GO:0071385 68 0.010
cellular response to alcohol GO:0097306 87 0.010
muscle contraction GO:0006936 88 0.010
chemosensory behavior GO:0007635 2 0.010
circadian rhythm GO:0007623 88 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
regulation of kinase activity GO:0043549 117 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
response to purine containing compound GO:0014074 126 0.010
negative regulation of secretion GO:0051048 82 0.010
negative regulation of secretion by cell GO:1903531 72 0.010
regulation of blood vessel size GO:0050880 89 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
cellular protein localization GO:0034613 122 0.010
negative regulation of cell proliferation GO:0008285 119 0.010
carbohydrate homeostasis GO:0033500 75 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010
regulation of metal ion transport GO:0010959 118 0.010
multicellular organism growth GO:0035264 1 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
forebrain development GO:0030900 98 0.010

Ces4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.036
sensory system disease DOID:0050155 0 0.023
disease of metabolism DOID:0014667 0 0.015
musculoskeletal system disease DOID:17 0 0.014
central nervous system disease DOID:331 0 0.014
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013
disease of cellular proliferation DOID:14566 0 0.010
retinal disease DOID:5679 0 0.010