Rattus norvegicus

0 known processes

Emilin1

elastin microfibril interfacer 1

Emilin1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of multicellular organismal process GO:0051240 387 0.109
transcription from rna polymerase ii promoter GO:0006366 252 0.104
response to cytokine GO:0034097 215 0.081
transcription dna templated GO:0006351 377 0.081
response to growth factor GO:0070848 189 0.078
nucleic acid templated transcription GO:0097659 379 0.073
rna biosynthetic process GO:0032774 380 0.072
positive regulation of biosynthetic process GO:0009891 319 0.071
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.067
reproductive process GO:0022414 372 0.065
response to estrogen GO:0043627 232 0.063
negative regulation of macromolecule metabolic process GO:0010605 260 0.062
response to lipopolysaccharide GO:0032496 191 0.056
response to external biotic stimulus GO:0043207 221 0.056
regulation of multicellular organismal development GO:2000026 376 0.055
regulation of protein metabolic process GO:0051246 289 0.053
aging GO:0007568 241 0.052
embryonic skeletal system development GO:0048706 3 0.051
positive regulation of gene expression GO:0010628 244 0.051
developmental process involved in reproduction GO:0003006 159 0.051
intracellular signal transduction GO:0035556 314 0.051
positive regulation of developmental process GO:0051094 283 0.050
regulation of rna biosynthetic process GO:2001141 381 0.050
response to hypoxia GO:0001666 231 0.048
regulation of cellular protein metabolic process GO:0032268 267 0.048
response to acid chemical GO:0001101 222 0.047
nucleoside phosphate metabolic process GO:0006753 283 0.047
response to extracellular stimulus GO:0009991 380 0.046
organonitrogen compound biosynthetic process GO:1901566 167 0.046
multicellular organismal reproductive process GO:0048609 233 0.045
regulation of nucleic acid templated transcription GO:1903506 380 0.044
positive regulation of cellular biosynthetic process GO:0031328 295 0.043
cellular response to cytokine stimulus GO:0071345 127 0.043
cellular component assembly GO:0022607 360 0.042
cellular response to organic cyclic compound GO:0071407 202 0.042
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.042
cellular response to oxygen containing compound GO:1901701 386 0.042
response to oxygen levels GO:0070482 265 0.042
carbohydrate derivative metabolic process GO:1901135 346 0.041
biological adhesion GO:0022610 110 0.040
skeletal system development GO:0001501 41 0.040
macromolecular complex subunit organization GO:0043933 339 0.039
single organism biosynthetic process GO:0044711 342 0.039
positive regulation of cell differentiation GO:0045597 217 0.039
regulation of catalytic activity GO:0050790 304 0.039
rna metabolic process GO:0016070 406 0.038
cellular component morphogenesis GO:0032989 155 0.038
positive regulation of transcription dna templated GO:0045893 197 0.038
response to inorganic substance GO:0010035 377 0.037
cellular response to lipid GO:0071396 201 0.037
positive regulation of signal transduction GO:0009967 175 0.036
response to nutrient levels GO:0031667 370 0.036
positive regulation of neurogenesis GO:0050769 165 0.036
regulation of rna metabolic process GO:0051252 391 0.036
regulation of intracellular signal transduction GO:1902531 218 0.036
regulation of transcription dna templated GO:0006355 374 0.036
cell motility GO:0048870 202 0.036
response to glucocorticoid GO:0051384 223 0.035
positive regulation of nucleic acid templated transcription GO:1903508 197 0.035
anatomical structure morphogenesis GO:0009653 298 0.035
single organism reproductive process GO:0044702 297 0.035
cellular response to peptide hormone stimulus GO:0071375 120 0.034
cellular response to hormone stimulus GO:0032870 247 0.033
cellular response to organonitrogen compound GO:0071417 197 0.033
regulation of programmed cell death GO:0043067 341 0.033
organic acid metabolic process GO:0006082 292 0.033
regulation of signal transduction GO:0009966 318 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.032
regulation of cellular component movement GO:0051270 150 0.032
cellular catabolic process GO:0044248 295 0.032
cellular response to endogenous stimulus GO:0071495 377 0.032
response to peptide hormone GO:0043434 278 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
cellular amino acid metabolic process GO:0006520 107 0.031
purine containing compound metabolic process GO:0072521 253 0.031
programmed cell death GO:0012501 392 0.030
purine nucleotide metabolic process GO:0006163 229 0.030
negative regulation of metabolic process GO:0009892 331 0.030
cellular amine metabolic process GO:0044106 38 0.030
neuron projection development GO:0031175 273 0.030
reproductive structure development GO:0048608 128 0.030
multi organism reproductive process GO:0044703 262 0.030
positive regulation of rna biosynthetic process GO:1902680 197 0.030
female gonad development GO:0008585 53 0.029
carbohydrate derivative biosynthetic process GO:1901137 124 0.029
negative regulation of cellular metabolic process GO:0031324 281 0.029
regulation of phosphate metabolic process GO:0019220 349 0.029
development of primary sexual characteristics GO:0045137 107 0.029
reproduction GO:0000003 245 0.029
positive regulation of signaling GO:0023056 270 0.029
regulation of apoptotic process GO:0042981 335 0.029
nucleotide metabolic process GO:0009117 279 0.028
response to estradiol GO:0032355 164 0.028
tissue development GO:0009888 252 0.028
circulatory system development GO:0072359 134 0.028
female pregnancy GO:0007565 122 0.027
renal system development GO:0072001 67 0.027
cellular component biogenesis GO:0044085 368 0.027
glycosaminoglycan biosynthetic process GO:0006024 4 0.026
response to wounding GO:0009611 254 0.026
proteolysis GO:0006508 175 0.026
response to mechanical stimulus GO:0009612 134 0.025
regulation of molecular function GO:0065009 398 0.025
secretion GO:0046903 307 0.025
cell activation GO:0001775 97 0.025
response to reactive oxygen species GO:0000302 120 0.025
reproductive system development GO:0061458 128 0.025
response to peptide GO:1901652 292 0.024
response to biotic stimulus GO:0009607 226 0.024
cellular response to growth factor stimulus GO:0071363 162 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
mrna transcription GO:0009299 2 0.024
negative regulation of gene expression GO:0010629 199 0.024
negative regulation of protein metabolic process GO:0051248 114 0.024
cellular response to external stimulus GO:0071496 118 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
catabolic process GO:0009056 351 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
head development GO:0060322 247 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
regulation of hydrolase activity GO:0051336 143 0.023
cellular response to peptide GO:1901653 133 0.023
ras protein signal transduction GO:0007265 29 0.023
organic substance catabolic process GO:1901575 316 0.023
macromolecule localization GO:0033036 252 0.022
cell projection organization GO:0030030 302 0.022
female sex differentiation GO:0046660 59 0.022
wound healing GO:0042060 122 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
embryonic pattern specification GO:0009880 1 0.022
response to decreased oxygen levels GO:0036293 237 0.022
cardiovascular system development GO:0072358 134 0.022
regulation of cellular component organization GO:0051128 368 0.022
oxoacid metabolic process GO:0043436 290 0.021
localization of cell GO:0051674 202 0.021
positive regulation of molecular function GO:0044093 230 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
regulation of metanephros development GO:0072215 4 0.021
urogenital system development GO:0001655 78 0.021
carboxylic acid metabolic process GO:0019752 289 0.021
sex differentiation GO:0007548 113 0.021
ossification GO:0001503 70 0.021
protein heterooligomerization GO:0051291 89 0.021
homeostatic process GO:0042592 331 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.020
single organism intracellular transport GO:1902582 166 0.020
cellular response to acid chemical GO:0071229 75 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
heart morphogenesis GO:0003007 3 0.020
regulation of neuron projection development GO:0010975 161 0.020
regulation of cell differentiation GO:0045595 320 0.020
positive regulation of nervous system development GO:0051962 178 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.020
cellular response to stress GO:0033554 269 0.020
embryonic cranial skeleton morphogenesis GO:0048701 2 0.020
cell migration involved in metanephros development GO:0035788 2 0.020
cell migration GO:0016477 197 0.020
growth GO:0040007 165 0.020
gastrulation GO:0007369 2 0.019
regulation of neuron death GO:1901214 115 0.019
embryonic skeletal system morphogenesis GO:0048704 3 0.019
tissue remodeling GO:0048771 40 0.019
cellular response to mechanical stimulus GO:0071260 48 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
regulation of nucleotide metabolic process GO:0006140 117 0.018
eye morphogenesis GO:0048592 4 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
amine metabolic process GO:0009308 38 0.018
gonad development GO:0008406 104 0.018
response to nutrient GO:0007584 248 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
cell adhesion GO:0007155 110 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
rhythmic process GO:0048511 156 0.017
regulation of cell development GO:0060284 263 0.017
organelle organization GO:0006996 266 0.017
cell projection morphogenesis GO:0048858 123 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
cell morphogenesis GO:0000902 142 0.017
response to ketone GO:1901654 182 0.017
regulation of protein modification process GO:0031399 194 0.017
central nervous system development GO:0007417 311 0.017
purine nucleotide biosynthetic process GO:0006164 83 0.017
odontogenesis GO:0042476 32 0.017
protein complex assembly GO:0006461 263 0.017
organ morphogenesis GO:0009887 75 0.017
gland development GO:0048732 155 0.017
ameboidal type cell migration GO:0001667 26 0.017
response to metal ion GO:0010038 253 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
negative regulation of developmental process GO:0051093 125 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
response to oxidative stress GO:0006979 186 0.016
response to amino acid GO:0043200 75 0.016
brain development GO:0007420 247 0.016
response to other organism GO:0051707 220 0.016
negative regulation of cell death GO:0060548 229 0.016
spindle organization GO:0007051 2 0.016
protein complex subunit organization GO:0071822 302 0.016
cellular ketone metabolic process GO:0042180 51 0.016
response to alkaloid GO:0043279 132 0.016
aminoglycan biosynthetic process GO:0006023 4 0.016
neuron development GO:0048666 286 0.016
organophosphate metabolic process GO:0019637 370 0.016
inflammatory response GO:0006954 150 0.016
negative regulation of response to stimulus GO:0048585 155 0.015
positive regulation of hydrolase activity GO:0051345 86 0.015
apoptotic process GO:0006915 381 0.015
formation of primary germ layer GO:0001704 1 0.015
regulation of cell motility GO:2000145 131 0.015
purine containing compound biosynthetic process GO:0072522 85 0.015
chemical homeostasis GO:0048878 292 0.015
regulation of phosphorylation GO:0042325 248 0.015
camera type eye development GO:0043010 48 0.015
ion homeostasis GO:0050801 212 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.015
anterior posterior pattern specification GO:0009952 1 0.015
development of primary female sexual characteristics GO:0046545 56 0.015
response to hexose GO:0009746 144 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
macromolecular complex assembly GO:0065003 273 0.015
vasculature development GO:0001944 70 0.015
cellular response to abiotic stimulus GO:0071214 85 0.015
cellular response to alcohol GO:0097306 87 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.014
ovulation cycle GO:0042698 67 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
response to glucose GO:0009749 136 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
leukocyte activation GO:0045321 76 0.014
response to monosaccharide GO:0034284 159 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
response to hydrogen peroxide GO:0042542 89 0.014
dna replication GO:0006260 37 0.014
neuron projection morphogenesis GO:0048812 122 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
actin crosslink formation GO:0051764 3 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
cellular homeostasis GO:0019725 252 0.014
response to bacterium GO:0009617 200 0.014
response to corticosteroid GO:0031960 235 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
regulation of mapk cascade GO:0043408 116 0.014
male sex differentiation GO:0046661 64 0.014
sensory organ development GO:0007423 74 0.013
single organism cell adhesion GO:0098602 46 0.013
dna metabolic process GO:0006259 96 0.013
response to fluoride GO:1902617 3 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
response to radiation GO:0009314 137 0.013
regulation of cell projection organization GO:0031344 175 0.013
single organism catabolic process GO:0044712 283 0.013
anatomical structure formation involved in morphogenesis GO:0048646 83 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
cellular component movement GO:0006928 248 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
positive regulation of stem cell differentiation GO:2000738 2 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
regulation of nervous system development GO:0051960 264 0.013
cellular response to extracellular stimulus GO:0031668 73 0.013
cytoplasmic transport GO:0016482 115 0.013
cell part morphogenesis GO:0032990 123 0.013
cellular chemical homeostasis GO:0055082 247 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
regulation of transferase activity GO:0051338 123 0.012
multicellular organism reproduction GO:0032504 233 0.012
nucleoside metabolic process GO:0009116 179 0.012
regulation of cell proliferation GO:0042127 359 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
multicellular organism growth GO:0035264 1 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
heart development GO:0007507 72 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
protein oligomerization GO:0051259 191 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
response to carbohydrate GO:0009743 183 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
regulation of fat cell differentiation GO:0045598 3 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
eye development GO:0001654 50 0.012
gamete generation GO:0007276 124 0.012
regulation of neurogenesis GO:0050767 247 0.012
protein complex biogenesis GO:0070271 263 0.012
epithelium development GO:0060429 96 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
neuron differentiation GO:0030182 368 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
regulation of cell migration GO:0030334 128 0.011
positive regulation of cell communication GO:0010647 271 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
epithelial cell differentiation GO:0030855 71 0.011
neuron death GO:0070997 127 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
peptidyl amino acid modification GO:0018193 126 0.011
nitrogen compound transport GO:0071705 229 0.011
camera type eye morphogenesis GO:0048593 2 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
muscle cell differentiation GO:0042692 52 0.011
sexual reproduction GO:0019953 148 0.011
multi multicellular organism process GO:0044706 138 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
single organism organelle organization GO:1902589 180 0.011
response to interleukin 1 GO:0070555 55 0.011
development of primary male sexual characteristics GO:0046546 59 0.011
regeneration GO:0031099 163 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
response to insulin GO:0032868 133 0.011
response to purine containing compound GO:0014074 126 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010
negative regulation of molecular function GO:0044092 133 0.010
response to vitamin GO:0033273 131 0.010
purine ribonucleotide biosynthetic process GO:0009152 81 0.010
protein phosphorylation GO:0006468 345 0.010
positive regulation of cell development GO:0010720 176 0.010
cellular response to metal ion GO:0071248 55 0.010
male gamete generation GO:0048232 99 0.010
negative regulation of innate immune response GO:0045824 4 0.010
actin cytoskeleton organization GO:0030036 73 0.010
negative regulation of transport GO:0051051 136 0.010

Emilin1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.112
musculoskeletal system disease DOID:17 0 0.112
nervous system disease DOID:863 0 0.024
muscular disease DOID:0080000 0 0.018
connective tissue disease DOID:65 0 0.016
central nervous system disease DOID:331 0 0.012
sensory system disease DOID:0050155 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010
osteochondrodysplasia DOID:2256 0 0.010
bone development disease DOID:0080006 0 0.010
bone disease DOID:0080001 0 0.010