Rattus norvegicus

8 known processes

Dad1

defender against cell death 1

Dad1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 3 0.321
positive regulation of phosphate metabolic process GO:0045937 262 0.182
rna biosynthetic process GO:0032774 380 0.172
regulation of cellular component organization GO:0051128 368 0.161
pyrimidine nucleotide biosynthetic process GO:0006221 9 0.160
pyrimidine nucleotide metabolic process GO:0006220 9 0.153
homeostatic process GO:0042592 331 0.145
pyrimidine ribonucleoside triphosphate biosynthetic process GO:0009209 2 0.136
neuron differentiation GO:0030182 368 0.125
retinal metabolic process GO:0042574 3 0.110
positive regulation of camp biosynthetic process GO:0030819 28 0.103
regulation of rna metabolic process GO:0051252 391 0.101
response to amine GO:0014075 46 0.100
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.097
camp metabolic process GO:0046058 63 0.094
regulation of purine nucleotide metabolic process GO:1900542 115 0.094
tissue development GO:0009888 252 0.093
regulation of neurogenesis GO:0050767 247 0.089
protein oligomerization GO:0051259 191 0.084
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.083
pyrimidine ribonucleotide metabolic process GO:0009218 5 0.082
regulation of nucleotide metabolic process GO:0006140 117 0.082
cell projection organization GO:0030030 302 0.080
regulation of neuron differentiation GO:0045664 208 0.079
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.078
regulation of signal transduction GO:0009966 318 0.078
positive regulation of biosynthetic process GO:0009891 319 0.077
regulation of camp biosynthetic process GO:0030817 38 0.075
regulation of transcription dna templated GO:0006355 374 0.075
reproduction GO:0000003 245 0.074
response to purine containing compound GO:0014074 126 0.074
positive regulation of multicellular organismal process GO:0051240 387 0.073
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.071
pyrimidine nucleoside triphosphate metabolic process GO:0009147 4 0.071
response to ketone GO:1901654 182 0.070
hexitol biosynthetic process GO:0019406 1 0.070
neuron projection development GO:0031175 273 0.070
intracellular signal transduction GO:0035556 314 0.069
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.069
ctp metabolic process GO:0046036 1 0.068
ctp biosynthetic process GO:0006241 1 0.065
aging GO:0007568 241 0.065
programmed cell death GO:0012501 392 0.064
regulation of cell projection organization GO:0031344 175 0.064
transcription from rna polymerase ii promoter GO:0006366 252 0.064
regulation of nucleotide biosynthetic process GO:0030808 47 0.063
chemical homeostasis GO:0048878 292 0.061
transcription dna templated GO:0006351 377 0.058
cyclic nucleotide metabolic process GO:0009187 80 0.058
cellular response to lipid GO:0071396 201 0.057
rna metabolic process GO:0016070 406 0.056
response to alkaloid GO:0043279 132 0.056
regulation of cell development GO:0060284 263 0.055
guanosine containing compound metabolic process GO:1901068 74 0.054
purine ribonucleotide metabolic process GO:0009150 227 0.054
oxoacid metabolic process GO:0043436 290 0.053
cellular response to oxidative stress GO:0034599 76 0.053
brain renin angiotensin system GO:0002035 3 0.052
positive regulation of camp metabolic process GO:0030816 31 0.050
positive regulation of cell proliferation GO:0008284 249 0.049
second messenger mediated signaling GO:0019932 51 0.048
neurological system process GO:0050877 219 0.047
cellular homeostasis GO:0019725 252 0.046
positive regulation of transcription dna templated GO:0045893 197 0.046
positive regulation of developmental process GO:0051094 283 0.046
positive regulation of nucleotide metabolic process GO:0045981 91 0.045
cellular component biogenesis GO:0044085 368 0.045
positive regulation of cellular biosynthetic process GO:0031328 295 0.045
cyclic purine nucleotide metabolic process GO:0052652 62 0.045
regulation of multicellular organismal development GO:2000026 376 0.045
regulation of rna biosynthetic process GO:2001141 381 0.045
positive regulation of cell differentiation GO:0045597 217 0.044
regulation of immune system process GO:0002682 123 0.044
positive regulation of cellular component organization GO:0051130 200 0.043
secretion GO:0046903 307 0.043
secretion by cell GO:0032940 248 0.043
multicellular organism reproduction GO:0032504 233 0.042
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.041
regulation of nervous system development GO:0051960 264 0.041
immune system process GO:0002376 204 0.041
positive regulation of secretion GO:0051047 140 0.041
response to glucose GO:0009749 136 0.041
negative regulation of metabolic process GO:0009892 331 0.041
ribose phosphate metabolic process GO:0019693 235 0.040
positive regulation of transport GO:0051050 245 0.040
positive regulation of cell projection organization GO:0031346 111 0.039
response to extracellular stimulus GO:0009991 380 0.039
neuron development GO:0048666 286 0.039
ion homeostasis GO:0050801 212 0.038
positive regulation of gene expression GO:0010628 244 0.038
cellular response to oxygen containing compound GO:1901701 386 0.037
ribonucleoside metabolic process GO:0009119 174 0.037
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.037
purine nucleotide metabolic process GO:0006163 229 0.035
forebrain development GO:0030900 98 0.035
response to peptide GO:1901652 292 0.034
neuron death GO:0070997 127 0.034
regulation of molecular function GO:0065009 398 0.034
single organism intracellular transport GO:1902582 166 0.034
response to camp GO:0051591 91 0.034
golgi vesicle transport GO:0048193 22 0.034
negative regulation of programmed cell death GO:0043069 183 0.034
regulation of phosphate metabolic process GO:0019220 349 0.034
regulation of nucleic acid templated transcription GO:1903506 380 0.033
glycosyl compound metabolic process GO:1901657 182 0.033
positive regulation of phosphorus metabolic process GO:0010562 262 0.033
purine nucleoside metabolic process GO:0042278 169 0.032
myeloid leukocyte differentiation GO:0002573 20 0.032
purine ribonucleoside metabolic process GO:0046128 168 0.032
regulation of apoptotic process GO:0042981 335 0.032
protein phosphorylation GO:0006468 345 0.032
regulation of neuron projection development GO:0010975 161 0.032
cellular response to fatty acid GO:0071398 29 0.032
regulation of intracellular signal transduction GO:1902531 218 0.031
brain development GO:0007420 247 0.031
regulation of cellular catabolic process GO:0031329 101 0.030
protein complex assembly GO:0006461 263 0.030
cellular ketone metabolic process GO:0042180 51 0.029
regulation of catalytic activity GO:0050790 304 0.029
response to glucocorticoid GO:0051384 223 0.029
regulation of secretion by cell GO:1903530 208 0.029
pyrimidine containing compound metabolic process GO:0072527 20 0.029
positive regulation of rna biosynthetic process GO:1902680 197 0.028
regulation of blood vessel size GO:0050880 89 0.028
gland development GO:0048732 155 0.028
central nervous system development GO:0007417 311 0.028
blood circulation GO:0008015 183 0.028
reproductive process GO:0022414 372 0.028
positive regulation of nucleic acid templated transcription GO:1903508 197 0.028
cyclic nucleotide biosynthetic process GO:0009190 63 0.028
nucleotide metabolic process GO:0009117 279 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.027
nucleic acid templated transcription GO:0097659 379 0.027
protein complex biogenesis GO:0070271 263 0.027
wound healing GO:0042060 122 0.027
response to oxidative stress GO:0006979 186 0.027
regulation of camp metabolic process GO:0030814 43 0.027
positive regulation of cell development GO:0010720 176 0.027
metal ion homeostasis GO:0055065 186 0.026
heart morphogenesis GO:0003007 3 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.025
response to oxygen radical GO:0000305 8 0.025
purine containing compound metabolic process GO:0072521 253 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
carbohydrate metabolic process GO:0005975 130 0.024
camp biosynthetic process GO:0006171 47 0.024
single organism reproductive process GO:0044702 297 0.024
regulation of anatomical structure size GO:0090066 135 0.024
positive regulation of nervous system development GO:0051962 178 0.024
response to peptide hormone GO:0043434 278 0.023
limbic system development GO:0021761 38 0.023
circulatory system process GO:0003013 183 0.023
response to testosterone GO:0033574 55 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
cellular cation homeostasis GO:0030003 180 0.023
protein autophosphorylation GO:0046777 66 0.022
cation transmembrane transport GO:0098655 263 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
regulation of catabolic process GO:0009894 113 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
cellular component assembly GO:0022607 360 0.022
telencephalon development GO:0021537 62 0.022
multi organism reproductive process GO:0044703 262 0.022
gtp metabolic process GO:0046039 72 0.022
hippocampus development GO:0021766 30 0.022
nucleoside triphosphate metabolic process GO:0009141 144 0.022
kidney development GO:0001822 67 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
metal ion transport GO:0030001 289 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
epithelium development GO:0060429 96 0.021
positive regulation of cell communication GO:0010647 271 0.021
protein complex subunit organization GO:0071822 302 0.020
cell morphogenesis involved in differentiation GO:0000904 119 0.020
response to acid chemical GO:0001101 222 0.020
pyrimidine ribonucleotide biosynthetic process GO:0009220 5 0.020
cellular chemical homeostasis GO:0055082 247 0.020
response to estrogen GO:0043627 232 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.020
negative regulation of developmental process GO:0051093 125 0.019
cellular modified amino acid metabolic process GO:0006575 61 0.019
intracellular transport GO:0046907 185 0.019
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.019
organophosphate biosynthetic process GO:0090407 143 0.019
head development GO:0060322 247 0.019
vascular process in circulatory system GO:0003018 96 0.019
cell motility GO:0048870 202 0.019
response to monosaccharide GO:0034284 159 0.018
organic acid metabolic process GO:0006082 292 0.018
organ morphogenesis GO:0009887 75 0.018
regulation of tube size GO:0035150 89 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.017
response to bacterium GO:0009617 200 0.017
protein ubiquitination GO:0016567 28 0.017
regulation of secretion GO:0051046 224 0.017
cellular amine metabolic process GO:0044106 38 0.017
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.017
pyrimidine ribonucleoside biosynthetic process GO:0046132 5 0.017
response to hexose GO:0009746 144 0.017
positive regulation of signal transduction GO:0009967 175 0.017
regulation of phosphorylation GO:0042325 248 0.016
positive regulation of intracellular signal transduction GO:1902533 138 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
regulation of hormone levels GO:0010817 187 0.016
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.016
regulation of neuron death GO:1901214 115 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
pallium development GO:0021543 42 0.016
organophosphate metabolic process GO:0019637 370 0.016
organophosphate catabolic process GO:0046434 148 0.016
cellular response to stress GO:0033554 269 0.016
regulation of blood pressure GO:0008217 83 0.016
positive regulation of secretion by cell GO:1903532 128 0.016
response to inorganic substance GO:0010035 377 0.016
regulation of response to external stimulus GO:0032101 106 0.015
regulation of body fluid levels GO:0050878 90 0.015
cytokine mediated signaling pathway GO:0019221 43 0.015
response to ethanol GO:0045471 162 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
cellular component movement GO:0006928 248 0.015
carboxylic acid metabolic process GO:0019752 289 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
positive regulation of hormone secretion GO:0046887 65 0.015
regulation of ligase activity GO:0051340 3 0.015
response to metal ion GO:0010038 253 0.015
regulation of transmembrane transporter activity GO:0022898 49 0.015
molting cycle process GO:0022404 2 0.014
cellular ion homeostasis GO:0006873 184 0.014
protein localization GO:0008104 191 0.014
regulation of corticotropin secretion GO:0051459 7 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
macromolecular complex assembly GO:0065003 273 0.014
sleep GO:0030431 30 0.014
catabolic process GO:0009056 351 0.014
regulation of cellular protein metabolic process GO:0032268 267 0.014
regulation of cell proliferation GO:0042127 359 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
gastrulation GO:0007369 2 0.014
positive regulation of signaling GO:0023056 270 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
regulation of cell differentiation GO:0045595 320 0.013
positive regulation of peptide secretion GO:0002793 52 0.013
extracellular matrix organization GO:0030198 13 0.013
positive regulation of immune system process GO:0002684 90 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
regulation of smoothened signaling pathway GO:0008589 2 0.013
regulation of myeloid cell differentiation GO:0045637 12 0.013
multicellular organism growth GO:0035264 1 0.013
response to carbohydrate GO:0009743 183 0.013
carbohydrate homeostasis GO:0033500 75 0.013
sequestering of calcium ion GO:0051208 8 0.013
cell cycle checkpoint GO:0000075 2 0.013
sequestering of metal ion GO:0051238 9 0.013
cellular response to acid chemical GO:0071229 75 0.013
regulation of hormone secretion GO:0046883 106 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
response to estradiol GO:0032355 164 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
regulation of neuron apoptotic process GO:0043523 83 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
regulation of peptide hormone secretion GO:0090276 80 0.012
response to wounding GO:0009611 254 0.012
negative regulation of signaling GO:0023057 157 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
response to lipopolysaccharide GO:0032496 191 0.012
negative regulation of myeloid cell differentiation GO:0045638 3 0.012
regulation of ryanodine sensitive calcium release channel activity GO:0060314 5 0.012
pyrimidine nucleoside biosynthetic process GO:0046134 5 0.012
protein localization to endoplasmic reticulum GO:0070972 1 0.012
axon ensheathment GO:0008366 40 0.012
negative regulation of cell death GO:0060548 229 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
tube development GO:0035295 89 0.012
signal release GO:0023061 145 0.012
ovulation cycle process GO:0022602 50 0.012
behavior GO:0007610 205 0.011
cation homeostasis GO:0055080 195 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
protein import GO:0017038 37 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
apoptotic process GO:0006915 381 0.011
cellular response to carbohydrate stimulus GO:0071322 72 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
regulation of response to wounding GO:1903034 69 0.011
myeloid cell differentiation GO:0030099 22 0.011
peptidyl amino acid modification GO:0018193 126 0.011
response to fatty acid GO:0070542 65 0.011
positive regulation of locomotion GO:0040017 102 0.011
negative regulation of protein modification by small protein conjugation or removal GO:1903321 4 0.011
ensheathment of neurons GO:0007272 40 0.011
regulation of homeostatic process GO:0032844 101 0.011
cellular response to glucose stimulus GO:0071333 65 0.011
gamete generation GO:0007276 124 0.011
muscle cell migration GO:0014812 36 0.011
regulation of membrane potential GO:0042391 110 0.011
negative regulation of gene expression GO:0010629 199 0.011
peptide hormone secretion GO:0030072 84 0.010
male gamete generation GO:0048232 99 0.010
hematopoietic or lymphoid organ development GO:0048534 36 0.010
cardiac muscle tissue morphogenesis GO:0055008 1 0.010
spermatogenesis GO:0007283 99 0.010
peptide secretion GO:0002790 86 0.010
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
endomembrane system organization GO:0010256 48 0.010
regulation of cell migration GO:0030334 128 0.010

Dad1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
osteochondrodysplasia DOID:2256 0 0.021
bone development disease DOID:0080006 0 0.021
bone disease DOID:0080001 0 0.021
disease of anatomical entity DOID:7 0 0.021
musculoskeletal system disease DOID:17 0 0.021
connective tissue disease DOID:65 0 0.021