Rattus norvegicus

0 known processes

Gdf9

growth differentiation factor 9

Gdf9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tissue development GO:0009888 252 0.236
response to inorganic substance GO:0010035 377 0.216
ion transmembrane transport GO:0034220 365 0.159
cell cell signaling GO:0007267 335 0.143
Human
reproductive system development GO:0061458 128 0.102
Human
blood circulation GO:0008015 183 0.101
regulation of secretion GO:0051046 224 0.100
Human
inorganic ion transmembrane transport GO:0098660 229 0.096
brain development GO:0007420 247 0.087
central nervous system development GO:0007417 311 0.084
divalent inorganic cation transport GO:0072511 134 0.080
ion homeostasis GO:0050801 212 0.076
cation homeostasis GO:0055080 195 0.073
homeostatic process GO:0042592 331 0.071
multicellular organism reproduction GO:0032504 233 0.070
Human Mouse
cation transport GO:0006812 382 0.068
regulation of apoptotic process GO:0042981 335 0.067
cation transmembrane transport GO:0098655 263 0.067
transmembrane transport GO:0055085 412 0.066
divalent inorganic cation homeostasis GO:0072507 165 0.066
negative regulation of programmed cell death GO:0043069 183 0.065
sensory perception GO:0007600 101 0.064
anatomical structure morphogenesis GO:0009653 298 0.063
reproduction GO:0000003 245 0.061
Human Mouse
macromolecular complex assembly GO:0065003 273 0.057
neuron development GO:0048666 286 0.055
sodium ion transmembrane transport GO:0035725 67 0.055
inorganic cation transmembrane transport GO:0098662 202 0.054
cellular divalent inorganic cation homeostasis GO:0072503 162 0.054
metal ion homeostasis GO:0055065 186 0.053
protein complex subunit organization GO:0071822 302 0.053
sensory organ development GO:0007423 74 0.051
chemical homeostasis GO:0048878 292 0.051
cellular ion homeostasis GO:0006873 184 0.050
muscle contraction GO:0006936 88 0.050
positive regulation of transport GO:0051050 245 0.050
regulation of cell proliferation GO:0042127 359 0.049
Human
feeding behavior GO:0007631 53 0.049
regulation of ion homeostasis GO:2000021 63 0.048
ovulation cycle process GO:0022602 50 0.047
Human
cellular component assembly GO:0022607 360 0.046
single organism reproductive process GO:0044702 297 0.046
Human Mouse
protein complex biogenesis GO:0070271 263 0.045
multicellular organismal reproductive process GO:0048609 233 0.045
Human Mouse
cytosolic calcium ion homeostasis GO:0051480 140 0.044
calcium ion homeostasis GO:0055074 162 0.043
regulation of secretion by cell GO:1903530 208 0.042
Human
cellular component biogenesis GO:0044085 368 0.041
regulation of muscle contraction GO:0006937 53 0.041
developmental process involved in reproduction GO:0003006 159 0.041
Human Mouse
synaptic transmission GO:0007268 235 0.039
action potential GO:0001508 54 0.039
positive regulation of cell migration GO:0030335 96 0.039
regulation of cellular localization GO:0060341 263 0.039
Human
cellular homeostasis GO:0019725 252 0.038
cardiovascular system development GO:0072358 134 0.038
metal ion transport GO:0030001 289 0.038
cellular calcium ion homeostasis GO:0006874 160 0.037
sex differentiation GO:0007548 113 0.037
Human
sodium ion transport GO:0006814 82 0.036
response to mechanical stimulus GO:0009612 134 0.036
secretion by cell GO:0032940 248 0.036
Human
dephosphorylation GO:0016311 98 0.034
regulation of membrane potential GO:0042391 110 0.034
g protein coupled receptor signaling pathway GO:0007186 242 0.034
cellular chemical homeostasis GO:0055082 247 0.034
neuron neuron synaptic transmission GO:0007270 60 0.034
cellular response to nitrogen compound GO:1901699 210 0.033
monovalent inorganic cation transport GO:0015672 172 0.033
regulation of hormone levels GO:0010817 187 0.033
Human
protein complex assembly GO:0006461 263 0.032
gland development GO:0048732 155 0.032
regulation of blood pressure GO:0008217 83 0.031
head development GO:0060322 247 0.031
development of primary female sexual characteristics GO:0046545 56 0.031
Human
response to estrogen GO:0043627 232 0.031
reproductive structure development GO:0048608 128 0.031
Human
reproductive process GO:0022414 372 0.031
Human Mouse
regulation of body fluid levels GO:0050878 90 0.031
amine metabolic process GO:0009308 38 0.031
negative regulation of hormone secretion GO:0046888 46 0.030
regulation of growth GO:0040008 105 0.030
Mouse
peptide secretion GO:0002790 86 0.030
sexual reproduction GO:0019953 148 0.029
Mouse
signal release GO:0023061 145 0.029
Human
regulation of heart rate GO:0002027 16 0.029
hormone secretion GO:0046879 115 0.028
Human
response to electrical stimulus GO:0051602 56 0.028
sequestering of metal ion GO:0051238 9 0.028
neurological system process GO:0050877 219 0.028
organic hydroxy compound metabolic process GO:1901615 115 0.027
circulatory system process GO:0003013 183 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
growth GO:0040007 165 0.027
Mouse
heart development GO:0007507 72 0.027
small molecule biosynthetic process GO:0044283 124 0.027
response to monosaccharide GO:0034284 159 0.027
response to ammonium ion GO:0060359 71 0.027
urinary bladder smooth muscle contraction GO:0014832 4 0.026
response to metal ion GO:0010038 253 0.026
developmental growth GO:0048589 100 0.026
Mouse
programmed cell death GO:0012501 392 0.026
regulation of cellular component organization GO:0051128 368 0.026
Mouse
response to alkaloid GO:0043279 132 0.026
negative regulation of apoptotic process GO:0043066 181 0.025
forebrain development GO:0030900 98 0.025
response to temperature stimulus GO:0009266 94 0.025
intracellular transport GO:0046907 185 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.025
peptide transport GO:0015833 97 0.025
cellular amine metabolic process GO:0044106 38 0.024
regulation of neuron projection development GO:0010975 161 0.024
cellular response to growth factor stimulus GO:0071363 162 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
response to ketone GO:1901654 182 0.024
cellular cation homeostasis GO:0030003 180 0.024
negative regulation of cell death GO:0060548 229 0.023
neuron projection morphogenesis GO:0048812 122 0.023
regulation of system process GO:0044057 208 0.023
Human
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.022
neuron differentiation GO:0030182 368 0.022
response to purine containing compound GO:0014074 126 0.022
cell projection morphogenesis GO:0048858 123 0.022
response to camp GO:0051591 91 0.022
regulation of anatomical structure size GO:0090066 135 0.021
spermatogenesis GO:0007283 99 0.021
regulation of anatomical structure morphogenesis GO:0022603 141 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
sodium ion homeostasis GO:0055078 23 0.021
motor neuron axon guidance GO:0008045 1 0.020
nitrogen compound transport GO:0071705 229 0.020
organic hydroxy compound biosynthetic process GO:1901617 51 0.020
response to decreased oxygen levels GO:0036293 237 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
ossification GO:0001503 70 0.020
somatostatin receptor signaling pathway GO:0038169 4 0.020
response to hypoxia GO:0001666 231 0.020
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.020
regulation of sodium ion transport GO:0002028 21 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
behavior GO:0007610 205 0.019
regulation of blood circulation GO:1903522 110 0.019
negative regulation of growth GO:0045926 37 0.019
Mouse
regulation of ion transmembrane transport GO:0034765 121 0.019
cell projection organization GO:0030030 302 0.019
cellular response to lipid GO:0071396 201 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
regulation of cellular component movement GO:0051270 150 0.019
neuron death GO:0070997 127 0.019
muscle structure development GO:0061061 87 0.019
cytoplasmic transport GO:0016482 115 0.018
eye morphogenesis GO:0048592 4 0.018
divalent metal ion transport GO:0070838 132 0.018
axon guidance GO:0007411 24 0.018
neuron projection development GO:0031175 273 0.018
regulation of synaptic transmission GO:0050804 141 0.018
response to oxygen levels GO:0070482 265 0.018
organ morphogenesis GO:0009887 75 0.018
response to organophosphorus GO:0046683 102 0.018
protein oligomerization GO:0051259 191 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.018
cellular response to organonitrogen compound GO:0071417 197 0.017
regeneration GO:0031099 163 0.017
apoptotic process GO:0006915 381 0.017
regulation of cell migration GO:0030334 128 0.017
positive regulation of secretion GO:0051047 140 0.017
saliva secretion GO:0046541 3 0.017
male gamete generation GO:0048232 99 0.017
calcium ion transport GO:0006816 131 0.017
multi organism reproductive process GO:0044703 262 0.017
Mouse
regulation of cell development GO:0060284 263 0.017
regulation of cell projection organization GO:0031344 175 0.017
negative regulation of secretion by cell GO:1903531 72 0.017
detection of chemical stimulus GO:0009593 10 0.017
heart process GO:0003015 57 0.017
response to glucocorticoid GO:0051384 223 0.017
positive regulation of signaling GO:0023056 270 0.017
response to nutrient levels GO:0031667 370 0.017
organ induction GO:0001759 1 0.017
ear development GO:0043583 21 0.016
positive regulation of saliva secretion GO:0046878 3 0.016
urinary tract smooth muscle contraction GO:0014848 4 0.016
axonogenesis GO:0007409 71 0.016
cellular component movement GO:0006928 248 0.016
response to reactive oxygen species GO:0000302 120 0.016
sequestering of calcium ion GO:0051208 8 0.016
locomotion GO:0040011 237 0.016
negative regulation of cytosolic calcium ion concentration GO:0051481 10 0.016
renal system process GO:0003014 40 0.016
neuron apoptotic process GO:0051402 88 0.016
somatostatin signaling pathway GO:0038170 4 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
Human
synaptic transmission glycinergic GO:0060012 2 0.015
negative regulation of chronic inflammatory response GO:0002677 2 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.015
eating behavior GO:0042755 21 0.015
response to peptide GO:1901652 292 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
response to corticosteroid GO:0031960 235 0.015
cytosolic calcium ion transport GO:0060401 39 0.015
cellular response to stress GO:0033554 269 0.015
rhythmic process GO:0048511 156 0.015
Human
positive regulation of fat cell proliferation GO:0070346 1 0.015
cellular response to oxygen containing compound GO:1901701 386 0.015
development of primary sexual characteristics GO:0045137 107 0.014
Human
calcium ion transport into cytosol GO:0060402 38 0.014
regulation of programmed cell death GO:0043067 341 0.014
regulation of cell growth GO:0001558 85 0.014
Mouse
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
response to wounding GO:0009611 254 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
multicellular organism growth GO:0035264 1 0.014
endoplasmic reticulum membrane organization GO:0090158 1 0.014
biological adhesion GO:0022610 110 0.014
negative regulation of transport GO:0051051 136 0.014
cellular ketone metabolic process GO:0042180 51 0.014
regulation of signal transduction GO:0009966 318 0.014
cellular response to inorganic substance GO:0071241 65 0.014
response to hexose GO:0009746 144 0.014
epithelium development GO:0060429 96 0.014
neuron fate commitment GO:0048663 4 0.014
fat cell proliferation GO:0070341 2 0.014
smooth muscle cell proliferation GO:0048659 77 0.013
renal system development GO:0072001 67 0.013
response to estradiol GO:0032355 164 0.013
response to peptide hormone GO:0043434 278 0.013
protein heterooligomerization GO:0051291 89 0.013
appendage morphogenesis GO:0035107 4 0.013
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.013
regulation of peptide transport GO:0090087 87 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
protein localization GO:0008104 191 0.013
positive regulation of peptide secretion GO:0002793 52 0.013
developmental induction GO:0031128 2 0.013
positive regulation of synaptic transmission GO:0050806 62 0.013
response to external biotic stimulus GO:0043207 221 0.013
cardiac muscle tissue growth GO:0055017 20 0.013
regulation of phosphate metabolic process GO:0019220 349 0.013
regulation of transporter activity GO:0032409 50 0.013
circulatory system development GO:0072359 134 0.013
regulation of peptide hormone secretion GO:0090276 80 0.012
endocrine process GO:0050886 32 0.012
Human
purine containing compound biosynthetic process GO:0072522 85 0.012
sensory perception of bitter taste GO:0050913 4 0.012
ovulation cycle GO:0042698 67 0.012
Human
organ formation GO:0048645 3 0.012
response to acid chemical GO:0001101 222 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.012
embryo development GO:0009790 49 0.012
axon development GO:0061564 96 0.012
regulation of nervous system development GO:0051960 264 0.012
oligopeptide transport GO:0006857 4 0.012
renal sodium excretion GO:0035812 20 0.012
response to oxidative stress GO:0006979 186 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
single organism membrane organization GO:0044802 74 0.012
response to extracellular stimulus GO:0009991 380 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
aging GO:0007568 241 0.012
striated muscle tissue development GO:0014706 58 0.012
response to prostaglandin f GO:0034696 4 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
negative regulation of long term synaptic potentiation GO:1900272 1 0.011
positive regulation of cell communication GO:0010647 271 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
amide transport GO:0042886 105 0.011
response to corticosterone GO:0051412 40 0.011
regulation of developmental growth GO:0048638 45 0.011
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.011
regulation of synaptic transmission cholinergic GO:0032222 6 0.011
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.011
response to carbohydrate GO:0009743 183 0.011
response to glucose GO:0009749 136 0.011
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.011
peptide hormone secretion GO:0030072 84 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
inner ear development GO:0048839 21 0.011
gamete generation GO:0007276 124 0.011
Mouse
defense response to gram negative bacterium GO:0050829 3 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
negative regulation of neuron apoptotic process GO:0043524 45 0.011
detection of stimulus GO:0051606 24 0.011
protein dephosphorylation GO:0006470 38 0.011
hepaticobiliary system development GO:0061008 90 0.011
phosphatidylcholine biosynthetic process GO:0006656 5 0.011
organophosphate metabolic process GO:0019637 370 0.011
regulation of protein transport GO:0051223 68 0.011
vascular process in circulatory system GO:0003018 96 0.011
muscle system process GO:0003012 115 0.010
regulation of cell motility GO:2000145 131 0.010
autophagic cell death GO:0048102 4 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
regulation of behavior GO:0050795 61 0.010
cell motility GO:0048870 202 0.010
positive regulation of peptide hormone secretion GO:0090277 50 0.010
muscle cell proliferation GO:0033002 84 0.010
specification of organ identity GO:0010092 2 0.010
response to hydrogen peroxide GO:0042542 89 0.010
regulation of smooth muscle cell proliferation GO:0048660 75 0.010
cell migration GO:0016477 197 0.010
positive regulation of developmental process GO:0051094 283 0.010
protein homooligomerization GO:0051260 91 0.010
chemotaxis GO:0006935 66 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
positive regulation of long term synaptic potentiation GO:1900273 4 0.010

Gdf9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
cardiovascular system disease DOID:1287 0 0.016
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.012