Rattus norvegicus

0 known processes

Gdf2

growth differentiation factor 2

Gdf2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 382 0.042
response to inorganic substance GO:0010035 377 0.042
carboxylic acid metabolic process GO:0019752 289 0.039
homeostatic process GO:0042592 331 0.039
regulation of multicellular organismal development GO:2000026 376 0.036
transmembrane transport GO:0055085 412 0.035
cellular response to oxygen containing compound GO:1901701 386 0.035
secretion GO:0046903 307 0.034
oxoacid metabolic process GO:0043436 290 0.034
organic acid metabolic process GO:0006082 292 0.032
ion transmembrane transport GO:0034220 365 0.032
neuron differentiation GO:0030182 368 0.032
response to nutrient levels GO:0031667 370 0.031
chemical homeostasis GO:0048878 292 0.030
regulation of cell differentiation GO:0045595 320 0.030
rna biosynthetic process GO:0032774 380 0.030
metal ion transport GO:0030001 289 0.030
central nervous system development GO:0007417 311 0.029
secretion by cell GO:0032940 248 0.029
cellular component biogenesis GO:0044085 368 0.029
response to peptide GO:1901652 292 0.028
reproductive process GO:0022414 372 0.028
response to acid chemical GO:0001101 222 0.028
cellular homeostasis GO:0019725 252 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.028
response to corticosteroid GO:0031960 235 0.028
cellular amine metabolic process GO:0044106 38 0.028
response to extracellular stimulus GO:0009991 380 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
cellular response to endogenous stimulus GO:0071495 377 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
cell projection organization GO:0030030 302 0.026
nitrogen compound transport GO:0071705 229 0.026
cellular component assembly GO:0022607 360 0.026
response to metal ion GO:0010038 253 0.026
programmed cell death GO:0012501 392 0.026
cellular ketone metabolic process GO:0042180 51 0.026
regulation of molecular function GO:0065009 398 0.026
cellular chemical homeostasis GO:0055082 247 0.025
regulation of ion transport GO:0043269 245 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
transcription dna templated GO:0006351 377 0.025
amine metabolic process GO:0009308 38 0.025
single organism reproductive process GO:0044702 297 0.025
anatomical structure morphogenesis GO:0009653 298 0.025
rna metabolic process GO:0016070 406 0.025
protein complex biogenesis GO:0070271 263 0.025
apoptotic process GO:0006915 381 0.025
response to peptide hormone GO:0043434 278 0.025
aging GO:0007568 241 0.024
regulation of rna biosynthetic process GO:2001141 381 0.024
positive regulation of developmental process GO:0051094 283 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
regulation of cellular component organization GO:0051128 368 0.024
regulation of nucleic acid templated transcription GO:1903506 380 0.024
regulation of signal transduction GO:0009966 318 0.024
neuron development GO:0048666 286 0.024
cellular response to stress GO:0033554 269 0.023
positive regulation of signaling GO:0023056 270 0.023
positive regulation of multicellular organismal process GO:0051240 387 0.023
regulation of transcription dna templated GO:0006355 374 0.023
regulation of cellular localization GO:0060341 263 0.023
response to ketone GO:1901654 182 0.023
regulation of neurogenesis GO:0050767 247 0.023
transcription from rna polymerase ii promoter GO:0006366 252 0.023
nucleic acid templated transcription GO:0097659 379 0.023
regulation of cell proliferation GO:0042127 359 0.023
response to glucocorticoid GO:0051384 223 0.023
brain development GO:0007420 247 0.023
ion homeostasis GO:0050801 212 0.023
regulation of programmed cell death GO:0043067 341 0.023
regulation of rna metabolic process GO:0051252 391 0.023
macromolecular complex assembly GO:0065003 273 0.023
head development GO:0060322 247 0.023
regulation of cell development GO:0060284 263 0.022
regulation of nervous system development GO:0051960 264 0.022
neuron projection development GO:0031175 273 0.022
regulation of apoptotic process GO:0042981 335 0.022
positive regulation of cell communication GO:0010647 271 0.022
response to oxygen levels GO:0070482 265 0.022
cellular component movement GO:0006928 248 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
cell cell signaling GO:0007267 335 0.022
cellular cation homeostasis GO:0030003 180 0.022
regulation of secretion GO:0051046 224 0.022
macromolecular complex subunit organization GO:0043933 339 0.021
protein complex subunit organization GO:0071822 302 0.021
catabolic process GO:0009056 351 0.021
circulatory system process GO:0003013 183 0.021
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
protein complex assembly GO:0006461 263 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
negative regulation of metabolic process GO:0009892 331 0.021
cation homeostasis GO:0055080 195 0.021
protein phosphorylation GO:0006468 345 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
regulation of system process GO:0044057 208 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
cellular ion homeostasis GO:0006873 184 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
intracellular signal transduction GO:0035556 314 0.020
anion transport GO:0006820 178 0.020
regulation of neuron differentiation GO:0045664 208 0.020
protein oligomerization GO:0051259 191 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
cation transmembrane transport GO:0098655 263 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
regulation of secretion by cell GO:1903530 208 0.020
multi organism reproductive process GO:0044703 262 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
g protein coupled receptor signaling pathway GO:0007186 242 0.020
regulation of hormone levels GO:0010817 187 0.019
response to decreased oxygen levels GO:0036293 237 0.019
cellular metal ion homeostasis GO:0006875 172 0.019
cellular response to organic cyclic compound GO:0071407 202 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
response to nutrient GO:0007584 248 0.019
positive regulation of transport GO:0051050 245 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
metal ion homeostasis GO:0055065 186 0.019
oxidation reduction process GO:0055114 304 0.019
cellular response to hormone stimulus GO:0032870 247 0.019
single organism biosynthetic process GO:0044711 342 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
organic anion transport GO:0015711 132 0.019
neurological system process GO:0050877 219 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
inorganic cation transmembrane transport GO:0098662 202 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
reproduction GO:0000003 245 0.018
cellular catabolic process GO:0044248 295 0.018
regulation of phosphorylation GO:0042325 248 0.018
organic substance catabolic process GO:1901575 316 0.018
calcium ion homeostasis GO:0055074 162 0.018
response to external biotic stimulus GO:0043207 221 0.018
response to hypoxia GO:0001666 231 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
response to estrogen GO:0043627 232 0.018
positive regulation of gene expression GO:0010628 244 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
lipid metabolic process GO:0006629 283 0.018
multicellular organism reproduction GO:0032504 233 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
single organism catabolic process GO:0044712 283 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
tissue development GO:0009888 252 0.018
response to oxidative stress GO:0006979 186 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.017
monovalent inorganic cation transport GO:0015672 172 0.017
response to wounding GO:0009611 254 0.017
response to hexose GO:0009746 144 0.017
cellular response to lipid GO:0071396 201 0.017
response to growth factor GO:0070848 189 0.017
blood circulation GO:0008015 183 0.017
response to glucose GO:0009749 136 0.017
response to monosaccharide GO:0034284 159 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
regulation of catalytic activity GO:0050790 304 0.017
negative regulation of gene expression GO:0010629 199 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
behavior GO:0007610 205 0.017
defense response GO:0006952 194 0.017
positive regulation of molecular function GO:0044093 230 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
positive regulation of cell death GO:0010942 184 0.017
heart morphogenesis GO:0003007 3 0.017
signal release GO:0023061 145 0.016
localization of cell GO:0051674 202 0.016
positive regulation of cell development GO:0010720 176 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
negative regulation of transport GO:0051051 136 0.016
positive regulation of nervous system development GO:0051962 178 0.016
regulation of cell projection organization GO:0031344 175 0.016
negative regulation of cell communication GO:0010648 158 0.016
carboxylic acid transport GO:0046942 115 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
regulation of protein metabolic process GO:0051246 289 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
locomotion GO:0040011 237 0.016
hormone secretion GO:0046879 115 0.016
organic acid transport GO:0015849 116 0.015
macromolecule localization GO:0033036 252 0.015
divalent inorganic cation transport GO:0072511 134 0.015
response to insulin GO:0032868 133 0.015
synaptic transmission GO:0007268 235 0.015
response to alkaloid GO:0043279 132 0.015
organelle organization GO:0006996 266 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
response to toxic substance GO:0009636 133 0.015
negative regulation of signaling GO:0023057 157 0.015
organophosphate metabolic process GO:0019637 370 0.015
immune system process GO:0002376 204 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
hormone transport GO:0009914 121 0.015
proteolysis GO:0006508 175 0.015
cell motility GO:0048870 202 0.015
response to carbohydrate GO:0009743 183 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
nucleotide metabolic process GO:0009117 279 0.015
amide transport GO:0042886 105 0.015
regulation of neuron projection development GO:0010975 161 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
intracellular transport GO:0046907 185 0.015
response to ethanol GO:0045471 162 0.015
cellular response to peptide GO:1901653 133 0.015
developmental process involved in reproduction GO:0003006 159 0.015
divalent metal ion transport GO:0070838 132 0.015
gastrulation GO:0007369 2 0.015
regulation of membrane potential GO:0042391 110 0.015
response to vitamin GO:0033273 131 0.014
rhythmic process GO:0048511 156 0.014
response to cytokine GO:0034097 215 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
axis specification GO:0009798 4 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
response to bacterium GO:0009617 200 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
reproductive system development GO:0061458 128 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
anterior posterior pattern specification GO:0009952 1 0.014
response to lipopolysaccharide GO:0032496 191 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
negative regulation of cell death GO:0060548 229 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
cellular component morphogenesis GO:0032989 155 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
gland development GO:0048732 155 0.014
single organism intracellular transport GO:1902582 166 0.014
vesicle mediated transport GO:0016192 181 0.014
response to other organism GO:0051707 220 0.014
action potential GO:0001508 54 0.014
cellular lipid metabolic process GO:0044255 208 0.013
sexual reproduction GO:0019953 148 0.013
positive regulation of signal transduction GO:0009967 175 0.013
reproductive structure development GO:0048608 128 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
response to mechanical stimulus GO:0009612 134 0.013
positive regulation of secretion GO:0051047 140 0.013
response to estradiol GO:0032355 164 0.013
cell morphogenesis GO:0000902 142 0.013
purine containing compound metabolic process GO:0072521 253 0.013
regulation of locomotion GO:0040012 148 0.013
positive regulation of secretion by cell GO:1903532 128 0.013
regulation of metal ion transport GO:0010959 118 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
cell part morphogenesis GO:0032990 123 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
calcium ion transport GO:0006816 131 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
multi multicellular organism process GO:0044706 138 0.013
regulation of protein modification process GO:0031399 194 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
carbohydrate metabolic process GO:0005975 130 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
single organism behavior GO:0044708 130 0.013
regulation of hormone secretion GO:0046883 106 0.013
regulation of homeostatic process GO:0032844 101 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
regeneration GO:0031099 163 0.013
regulation of anatomical structure size GO:0090066 135 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
response to radiation GO:0009314 137 0.013
positive regulation of ion transport GO:0043270 94 0.013
cell migration GO:0016477 197 0.012
positive regulation of protein modification process GO:0031401 142 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
peptide transport GO:0015833 97 0.012
sex differentiation GO:0007548 113 0.012
inflammatory response GO:0006954 150 0.012
negative regulation of molecular function GO:0044092 133 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
muscle system process GO:0003012 115 0.012
ras protein signal transduction GO:0007265 29 0.012
protein localization GO:0008104 191 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
cytoplasmic transport GO:0016482 115 0.012
female pregnancy GO:0007565 122 0.012
circadian rhythm GO:0007623 88 0.012
establishment of protein localization GO:0045184 141 0.012
cell projection morphogenesis GO:0048858 123 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
response to biotic stimulus GO:0009607 226 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
neuron projection morphogenesis GO:0048812 122 0.012
cellular response to external stimulus GO:0071496 118 0.012
cellular response to alcohol GO:0097306 87 0.011
non canonical wnt signaling pathway GO:0035567 3 0.011
response to reactive oxygen species GO:0000302 120 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
single organism organelle organization GO:1902589 180 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
sequestering of metal ion GO:0051238 9 0.011
regulation of peptide secretion GO:0002791 82 0.011
regulation of blood circulation GO:1903522 110 0.011
negative regulation of developmental process GO:0051093 125 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
negative regulation of secretion GO:0051048 82 0.011
gamete generation GO:0007276 124 0.011
peptide hormone secretion GO:0030072 84 0.011
muscle contraction GO:0006936 88 0.011
establishment of tissue polarity GO:0007164 2 0.011
sequestering of calcium ion GO:0051208 8 0.011
eye morphogenesis GO:0048592 4 0.011
sensory perception GO:0007600 101 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
regulation of cell motility GO:2000145 131 0.011
regulation of synaptic transmission GO:0050804 141 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
growth GO:0040007 165 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
regulation of peptide transport GO:0090087 87 0.011
cognition GO:0050890 92 0.011
circulatory system development GO:0072359 134 0.011
mesoderm development GO:0007498 2 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
limb morphogenesis GO:0035108 4 0.011
chromosome segregation GO:0007059 2 0.011
lipid storage GO:0019915 1 0.011
sodium ion transport GO:0006814 82 0.011
embryonic skeletal system development GO:0048706 3 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
cardiac chamber development GO:0003205 1 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
regulation of cellular component movement GO:0051270 150 0.011
signal transduction by phosphorylation GO:0023014 144 0.010
gonad development GO:0008406 104 0.010
neuromuscular process GO:0050905 2 0.010
response to purine containing compound GO:0014074 126 0.010
maintenance of location GO:0051235 17 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010
cardiovascular system development GO:0072358 134 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
regulation of hydrolase activity GO:0051336 143 0.010
peptide secretion GO:0002790 86 0.010
forebrain development GO:0030900 98 0.010
cell type specific apoptotic process GO:0097285 134 0.010
cellular response to steroid hormone stimulus GO:0071383 93 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
regulation of cell migration GO:0030334 128 0.010
protein homooligomerization GO:0051260 91 0.010
mapk cascade GO:0000165 140 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
cell adhesion GO:0007155 110 0.010
spermatogenesis GO:0007283 99 0.010
chemosensory behavior GO:0007635 2 0.010

Gdf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
sensory system disease DOID:0050155 0 0.018
disease of metabolism DOID:0014667 0 0.014
musculoskeletal system disease DOID:17 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
central nervous system disease DOID:331 0 0.011
retinal disease DOID:5679 0 0.010