Rattus norvegicus

0 known processes

Hgd

homogentisate 1, 2-dioxygenase

Hgd biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cell proliferation GO:0042127 359 0.130
carboxylic acid metabolic process GO:0019752 289 0.118
organic acid metabolic process GO:0006082 292 0.079
rna metabolic process GO:0016070 406 0.078
transcription dna templated GO:0006351 377 0.077
cellular amino acid metabolic process GO:0006520 107 0.071
response to corticosteroid GO:0031960 235 0.071
regulation of rna biosynthetic process GO:2001141 381 0.071
rna biosynthetic process GO:0032774 380 0.066
positive regulation of cell proliferation GO:0008284 249 0.064
negative regulation of cellular metabolic process GO:0031324 281 0.064
response to inorganic substance GO:0010035 377 0.058
homeostatic process GO:0042592 331 0.057
chemical homeostasis GO:0048878 292 0.056
secretion GO:0046903 307 0.055
positive regulation of response to stimulus GO:0048584 285 0.055
regulation of rna metabolic process GO:0051252 391 0.054
cellular response to oxygen containing compound GO:1901701 386 0.051
nucleic acid templated transcription GO:0097659 379 0.049
negative regulation of metabolic process GO:0009892 331 0.049
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.047
cellular component movement GO:0006928 248 0.047
regulation of molecular function GO:0065009 398 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.046
regulation of signal transduction GO:0009966 318 0.046
transmembrane transport GO:0055085 412 0.046
response to nutrient GO:0007584 248 0.045
positive regulation of multicellular organismal process GO:0051240 387 0.045
response to bacterium GO:0009617 200 0.045
transcription from rna polymerase ii promoter GO:0006366 252 0.044
response to extracellular stimulus GO:0009991 380 0.043
regulation of transcription dna templated GO:0006355 374 0.043
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.042
positive regulation of developmental process GO:0051094 283 0.042
programmed cell death GO:0012501 392 0.042
cation transport GO:0006812 382 0.042
regulation of nucleic acid templated transcription GO:1903506 380 0.041
oxoacid metabolic process GO:0043436 290 0.040
response to biotic stimulus GO:0009607 226 0.040
positive regulation of gene expression GO:0010628 244 0.040
regulation of apoptotic process GO:0042981 335 0.040
positive regulation of cellular biosynthetic process GO:0031328 295 0.040
macromolecule localization GO:0033036 252 0.039
cellular cation homeostasis GO:0030003 180 0.038
response to other organism GO:0051707 220 0.038
response to external biotic stimulus GO:0043207 221 0.038
regulation of programmed cell death GO:0043067 341 0.037
reproduction GO:0000003 245 0.036
ion transmembrane transport GO:0034220 365 0.036
response to nutrient levels GO:0031667 370 0.035
metal ion homeostasis GO:0055065 186 0.035
positive regulation of rna metabolic process GO:0051254 203 0.035
reproductive process GO:0022414 372 0.035
response to molecule of bacterial origin GO:0002237 194 0.034
regulation of protein metabolic process GO:0051246 289 0.034
regulation of secretion GO:0051046 224 0.034
cell cell signaling GO:0007267 335 0.034
nitrogen compound transport GO:0071705 229 0.034
organophosphate metabolic process GO:0019637 370 0.033
protein phosphorylation GO:0006468 345 0.033
cellular response to endogenous stimulus GO:0071495 377 0.033
multi organism reproductive process GO:0044703 262 0.033
multicellular organism reproduction GO:0032504 233 0.033
single organism reproductive process GO:0044702 297 0.033
single organism biosynthetic process GO:0044711 342 0.033
multicellular organismal reproductive process GO:0048609 233 0.032
anatomical structure morphogenesis GO:0009653 298 0.032
regulation of system process GO:0044057 208 0.032
aging GO:0007568 241 0.032
cell motility GO:0048870 202 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.031
response to metal ion GO:0010038 253 0.031
regulation of catalytic activity GO:0050790 304 0.031
amine metabolic process GO:0009308 38 0.031
response to peptide hormone GO:0043434 278 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
regulation of cellular protein metabolic process GO:0032268 267 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.030
cellular component assembly GO:0022607 360 0.030
positive regulation of signaling GO:0023056 270 0.030
negative regulation of cell death GO:0060548 229 0.030
positive regulation of biosynthetic process GO:0009891 319 0.030
secretion by cell GO:0032940 248 0.029
response to growth factor GO:0070848 189 0.029
catabolic process GO:0009056 351 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
tissue development GO:0009888 252 0.029
negative regulation of rna metabolic process GO:0051253 123 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.028
defense response GO:0006952 194 0.028
cellular ketone metabolic process GO:0042180 51 0.028
response to estrogen GO:0043627 232 0.028
negative regulation of multicellular organismal process GO:0051241 203 0.028
cellular chemical homeostasis GO:0055082 247 0.027
response to decreased oxygen levels GO:0036293 237 0.027
metal ion transport GO:0030001 289 0.027
intracellular signal transduction GO:0035556 314 0.027
cellular response to stress GO:0033554 269 0.027
organic substance catabolic process GO:1901575 316 0.027
regulation of locomotion GO:0040012 148 0.027
cation homeostasis GO:0055080 195 0.027
cell migration GO:0016477 197 0.026
cellular response to growth factor stimulus GO:0071363 162 0.026
cellular amine metabolic process GO:0044106 38 0.026
locomotion GO:0040011 237 0.026
response to hypoxia GO:0001666 231 0.026
regulation of nervous system development GO:0051960 264 0.026
ion homeostasis GO:0050801 212 0.026
positive regulation of molecular function GO:0044093 230 0.026
apoptotic process GO:0006915 381 0.026
regulation of secretion by cell GO:1903530 208 0.026
negative regulation of cellular biosynthetic process GO:0031327 161 0.026
response to estradiol GO:0032355 164 0.025
positive regulation of protein metabolic process GO:0051247 178 0.025
localization of cell GO:0051674 202 0.025
cellular response to lipid GO:0071396 201 0.025
regeneration GO:0031099 163 0.025
response to glucocorticoid GO:0051384 223 0.025
response to oxygen levels GO:0070482 265 0.025
divalent inorganic cation transport GO:0072511 134 0.025
cellular catabolic process GO:0044248 295 0.024
female pregnancy GO:0007565 122 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
response to transition metal nanoparticle GO:1990267 122 0.024
response to acid chemical GO:0001101 222 0.024
positive regulation of transcription dna templated GO:0045893 197 0.023
cellular divalent inorganic cation homeostasis GO:0072503 162 0.023
multi multicellular organism process GO:0044706 138 0.023
response to lipopolysaccharide GO:0032496 191 0.023
positive regulation of secretion by cell GO:1903532 128 0.023
regulation of cellular component organization GO:0051128 368 0.022
protein oligomerization GO:0051259 191 0.022
lipid localization GO:0010876 62 0.022
regulation of behavior GO:0050795 61 0.022
immune system process GO:0002376 204 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
cellular homeostasis GO:0019725 252 0.022
regulation of cellular component movement GO:0051270 150 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
organic acid biosynthetic process GO:0016053 83 0.022
regulation of protein modification process GO:0031399 194 0.021
muscle cell proliferation GO:0033002 84 0.021
regulation of phosphate metabolic process GO:0019220 349 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.021
single organism catabolic process GO:0044712 283 0.021
growth GO:0040007 165 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
divalent metal ion transport GO:0070838 132 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
positive regulation of cellular protein metabolic process GO:0032270 167 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
response to oxidative stress GO:0006979 186 0.020
negative regulation of cell proliferation GO:0008285 119 0.020
regulation of defense response GO:0031347 68 0.020
calcium ion transport GO:0006816 131 0.020
protein complex biogenesis GO:0070271 263 0.020
brain development GO:0007420 247 0.020
head development GO:0060322 247 0.020
sexual reproduction GO:0019953 148 0.020
negative regulation of biosynthetic process GO:0009890 168 0.019
organ morphogenesis GO:0009887 75 0.019
protein transport GO:0015031 132 0.019
cellular protein localization GO:0034613 122 0.019
small molecule biosynthetic process GO:0044283 124 0.019
response to mechanical stimulus GO:0009612 134 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.019
response to vitamin GO:0033273 131 0.019
positive regulation of cell death GO:0010942 184 0.019
signal release GO:0023061 145 0.019
regulation of ion transport GO:0043269 245 0.019
proteolysis GO:0006508 175 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
single organism intracellular transport GO:1902582 166 0.018
regulation of hormone levels GO:0010817 187 0.018
regulation of cellular localization GO:0060341 263 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
sensory organ development GO:0007423 74 0.018
response to hexose GO:0009746 144 0.018
central nervous system development GO:0007417 311 0.018
immune response GO:0006955 104 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
positive regulation of cell development GO:0010720 176 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
positive regulation of programmed cell death GO:0043068 157 0.017
fatty acid metabolic process GO:0006631 99 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
response to monosaccharide GO:0034284 159 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
carboxylic acid biosynthetic process GO:0046394 83 0.016
intracellular transport GO:0046907 185 0.016
lipid biosynthetic process GO:0008610 128 0.016
neuron projection development GO:0031175 273 0.016
protein localization GO:0008104 191 0.016
negative regulation of gene expression GO:0010629 199 0.016
cellular response to external stimulus GO:0071496 118 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
rhythmic process GO:0048511 156 0.016
response to carbohydrate GO:0009743 183 0.015
response to cytokine GO:0034097 215 0.015
regulation of phosphorylation GO:0042325 248 0.015
sterol homeostasis GO:0055092 3 0.015
protein complex subunit organization GO:0071822 302 0.015
positive regulation of secretion GO:0051047 140 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
positive regulation of signal transduction GO:0009967 175 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
macromolecular complex assembly GO:0065003 273 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
cellular component biogenesis GO:0044085 368 0.015
protein complex assembly GO:0006461 263 0.015
gamete generation GO:0007276 124 0.015
regulation of response to external stimulus GO:0032101 106 0.014
inflammatory response GO:0006954 150 0.014
vesicle mediated transport GO:0016192 181 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
negative regulation of signaling GO:0023057 157 0.014
purine containing compound metabolic process GO:0072521 253 0.014
regulation of growth GO:0040008 105 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
cytoplasmic transport GO:0016482 115 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
nucleotide metabolic process GO:0009117 279 0.014
regulation of cell differentiation GO:0045595 320 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
lipid metabolic process GO:0006629 283 0.014
cellular modified amino acid metabolic process GO:0006575 61 0.014
calcium ion homeostasis GO:0055074 162 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
regulation of cell development GO:0060284 263 0.014
regulation of cell growth GO:0001558 85 0.013
carbohydrate metabolic process GO:0005975 130 0.013
protein homooligomerization GO:0051260 91 0.013
regulation of cell motility GO:2000145 131 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
positive regulation of transport GO:0051050 245 0.013
positive regulation of protein modification process GO:0031401 142 0.013
response to glucose GO:0009749 136 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
cellular lipid metabolic process GO:0044255 208 0.013
negative regulation of developmental process GO:0051093 125 0.013
regulation of immune system process GO:0002682 123 0.013
regulation of blood circulation GO:1903522 110 0.013
smooth muscle cell proliferation GO:0048659 77 0.013
cardiovascular system development GO:0072358 134 0.013
blood vessel morphogenesis GO:0048514 58 0.013
heterocycle catabolic process GO:0046700 167 0.013
cell growth GO:0016049 104 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
hormone secretion GO:0046879 115 0.013
endocytosis GO:0006897 84 0.013
behavior GO:0007610 205 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
anion transport GO:0006820 178 0.013
cellular response to nitrogen compound GO:1901699 210 0.012
blood circulation GO:0008015 183 0.012
regulation of neurogenesis GO:0050767 247 0.012
peptidyl amino acid modification GO:0018193 126 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
circulatory system development GO:0072359 134 0.012
cell morphogenesis GO:0000902 142 0.012
lipid transport GO:0006869 61 0.012
response to insulin GO:0032868 133 0.012
positive regulation of immune system process GO:0002684 90 0.012
establishment of protein localization GO:0045184 141 0.012
ras protein signal transduction GO:0007265 29 0.012
regulation of cell migration GO:0030334 128 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
lipid storage GO:0019915 1 0.012
neuron death GO:0070997 127 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
response to reactive oxygen species GO:0000302 120 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
regulation of neuron death GO:1901214 115 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
mesoderm development GO:0007498 2 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
positive regulation of nervous system development GO:0051962 178 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
negative regulation of transport GO:0051051 136 0.012
negative regulation of molecular function GO:0044092 133 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
regulation of immune response GO:0050776 55 0.012
carboxylic acid transport GO:0046942 115 0.012
regulation of anatomical structure size GO:0090066 135 0.012
regulation of vesicle mediated transport GO:0060627 81 0.011
organic acid catabolic process GO:0016054 49 0.011
regulation of body fluid levels GO:0050878 90 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
organelle organization GO:0006996 266 0.011
cell projection organization GO:0030030 302 0.011
axis specification GO:0009798 4 0.011
positive regulation of cell motility GO:2000147 97 0.011
jak stat cascade GO:0007259 26 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
response to ethanol GO:0045471 162 0.011
peptide secretion GO:0002790 86 0.011
hepatocyte proliferation GO:0072574 3 0.011
amide transport GO:0042886 105 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
response to wounding GO:0009611 254 0.011
circulatory system process GO:0003013 183 0.011
response to radiation GO:0009314 137 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
cellular ion homeostasis GO:0006873 184 0.011
peptide transport GO:0015833 97 0.011
response to peptide GO:1901652 292 0.011
male gamete generation GO:0048232 99 0.011
response to increased oxygen levels GO:0036296 45 0.011
regulation of cell projection organization GO:0031344 175 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
positive regulation of cell communication GO:0010647 271 0.011
cation transmembrane transport GO:0098655 263 0.011
oxidation reduction process GO:0055114 304 0.010
neuron differentiation GO:0030182 368 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
regulation of transferase activity GO:0051338 123 0.010
developmental process involved in reproduction GO:0003006 159 0.010
epithelium development GO:0060429 96 0.010
negative regulation of cell communication GO:0010648 158 0.010
regulation of peptide transport GO:0090087 87 0.010
positive regulation of cellular catabolic process GO:0031331 71 0.010
tube development GO:0035295 89 0.010
purine nucleoside metabolic process GO:0042278 169 0.010

Hgd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011
musculoskeletal system disease DOID:17 0 0.011