Rattus norvegicus

0 known processes

Fcer1a

Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide

(Aliases: RATIGER01,Iger01)

Fcer1a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of lymphocyte chemotaxis GO:1901623 1 0.352
g protein coupled receptor signaling pathway GO:0007186 242 0.211
homeostatic process GO:0042592 331 0.139
purine containing compound biosynthetic process GO:0072522 85 0.113
circulatory system process GO:0003013 183 0.107
taxis GO:0042330 67 0.103
regulation of necroptotic process GO:0060544 2 0.101
eosinophil chemotaxis GO:0048245 3 0.096
lymphocyte chemotaxis GO:0048247 3 0.096
t cell chemotaxis GO:0010818 2 0.095
negative regulation of chronic inflammatory response GO:0002677 2 0.092
cellular response to oxygen containing compound GO:1901701 386 0.091
inflammatory response GO:0006954 150 0.089
blood circulation GO:0008015 183 0.087
regulation of t cell chemotaxis GO:0010819 1 0.086
cellular homeostasis GO:0019725 252 0.085
cytosolic calcium ion homeostasis GO:0051480 140 0.080
regulation of cell proliferation GO:0042127 359 0.078
positive regulation of multicellular organismal process GO:0051240 387 0.076
camp biosynthetic process GO:0006171 47 0.074
chemical homeostasis GO:0048878 292 0.071
metal ion homeostasis GO:0055065 186 0.071
purine nucleotide metabolic process GO:0006163 229 0.070
positive regulation of behavior GO:0048520 38 0.064
calcium ion homeostasis GO:0055074 162 0.063
cation homeostasis GO:0055080 195 0.062
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.061
macromolecule localization GO:0033036 252 0.060
organophosphate metabolic process GO:0019637 370 0.058
regulation of response to external stimulus GO:0032101 106 0.057
negative regulation of multicellular organismal process GO:0051241 203 0.056
purine ribonucleotide metabolic process GO:0009150 227 0.055
proteolysis GO:0006508 175 0.055
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.053
anion transport GO:0006820 178 0.051
response to inorganic substance GO:0010035 377 0.051
negative regulation of metabolic process GO:0009892 331 0.050
head development GO:0060322 247 0.050
t cell extravasation GO:0072683 1 0.050
cellular metal ion homeostasis GO:0006875 172 0.049
regulation of secretion GO:0051046 224 0.048
cellular response to lipopolysaccharide GO:0071222 55 0.048
divalent inorganic cation homeostasis GO:0072507 165 0.047
single organism reproductive process GO:0044702 297 0.046
regulation of t cell migration GO:2000404 1 0.046
cellular response to endogenous stimulus GO:0071495 377 0.046
organonitrogen compound biosynthetic process GO:1901566 167 0.046
central nervous system development GO:0007417 311 0.045
regulation of lymphocyte migration GO:2000401 1 0.045
negative regulation of cellular biosynthetic process GO:0031327 161 0.045
cation transport GO:0006812 382 0.044
interleukin 1 biosynthetic process GO:0042222 1 0.044
cellular response to biotic stimulus GO:0071216 59 0.043
neuron differentiation GO:0030182 368 0.043
positive regulation of signaling GO:0023056 270 0.041
negative regulation of response to tumor cell GO:0002835 2 0.041
lymphocyte migration GO:0072676 3 0.041
positive regulation of cytokine biosynthetic process GO:0042108 1 0.041
ion homeostasis GO:0050801 212 0.041
positive regulation of transport GO:0051050 245 0.040
response to wounding GO:0009611 254 0.040
response to decreased oxygen levels GO:0036293 237 0.039
programmed cell death GO:0012501 392 0.039
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.038
response to hydrogen peroxide GO:0042542 89 0.037
response to toxic substance GO:0009636 133 0.037
negative regulation of biosynthetic process GO:0009890 168 0.036
neuron neuron synaptic transmission GO:0007270 60 0.036
ribonucleotide biosynthetic process GO:0009260 85 0.035
cellular chemical homeostasis GO:0055082 247 0.035
nucleoside phosphate metabolic process GO:0006753 283 0.035
transmission of nerve impulse GO:0019226 42 0.034
regulation of nervous system development GO:0051960 264 0.034
single organism catabolic process GO:0044712 283 0.034
regulation of ion transport GO:0043269 245 0.033
organic hydroxy compound metabolic process GO:1901615 115 0.033
positive regulation of t cell migration GO:2000406 1 0.033
regulation of cytokine biosynthetic process GO:0042035 3 0.032
cellular response to vitamin k GO:0071307 1 0.032
regulation of cytokine production GO:0001817 56 0.032
signal transduction by phosphorylation GO:0023014 144 0.032
regulation of blood pressure GO:0008217 83 0.031
eosinophil migration GO:0072677 3 0.031
cellular response to lipid GO:0071396 201 0.031
chronic inflammatory response GO:0002544 16 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
regulation of neuron differentiation GO:0045664 208 0.031
regulation of chemotaxis GO:0050920 29 0.031
purine containing compound metabolic process GO:0072521 253 0.030
response to metal ion GO:0010038 253 0.030
positive regulation of cell proliferation GO:0008284 249 0.030
secretion GO:0046903 307 0.030
regulation of cell motility GO:2000145 131 0.029
cell motility GO:0048870 202 0.029
neuron development GO:0048666 286 0.029
ribose phosphate metabolic process GO:0019693 235 0.029
cytokine production GO:0001816 61 0.029
camp metabolic process GO:0046058 63 0.029
response to biotic stimulus GO:0009607 226 0.029
progesterone biosynthetic process GO:0006701 3 0.028
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.028
cellular divalent inorganic cation homeostasis GO:0072503 162 0.028
brain development GO:0007420 247 0.028
response to reactive oxygen species GO:0000302 120 0.027
synaptic transmission GO:0007268 235 0.027
positive regulation of secretion by cell GO:1903532 128 0.027
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.027
respiratory gaseous exchange GO:0007585 4 0.027
cellular response to external stimulus GO:0071496 118 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
regulation of intracellular signal transduction GO:1902531 218 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.026
tissue development GO:0009888 252 0.026
cd8 positive alpha beta t cell extravasation GO:0035697 0 0.025
acute inflammatory response GO:0002526 58 0.025
t cell migration GO:0072678 2 0.025
protein localization GO:0008104 191 0.025
dibenzo p dioxin metabolic process GO:0018894 10 0.025
mast cell migration GO:0097531 4 0.025
cellular response to ammonium ion GO:0071242 17 0.025
positive regulation of blood circulation GO:1903524 65 0.024
positive regulation of cell communication GO:0010647 271 0.024
cellular response to hexose stimulus GO:0071331 65 0.024
negative regulation of immune response to tumor cell GO:0002838 2 0.024
positive regulation of nervous system development GO:0051962 178 0.024
vascular process in circulatory system GO:0003018 96 0.024
regulation of cellular component organization GO:0051128 368 0.024
leydig cell differentiation GO:0033327 8 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
nucleotide biosynthetic process GO:0009165 98 0.024
regulation of metal ion transport GO:0010959 118 0.024
purine nucleotide biosynthetic process GO:0006164 83 0.024
intracellular signal transduction GO:0035556 314 0.024
response to external biotic stimulus GO:0043207 221 0.024
nucleoside phosphate biosynthetic process GO:1901293 102 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
regulation of phosphorus metabolic process GO:0051174 349 0.023
positive regulation of response to external stimulus GO:0032103 51 0.023
organophosphate biosynthetic process GO:0090407 143 0.023
defense response GO:0006952 194 0.023
positive regulation of t cell chemotaxis GO:0010820 1 0.023
response to growth factor GO:0070848 189 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
cellular ion homeostasis GO:0006873 184 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.022
organic substance catabolic process GO:1901575 316 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
biological adhesion GO:0022610 110 0.021
negative regulation of response to wounding GO:1903035 23 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.021
response to estrogen GO:0043627 232 0.021
regulation of cell differentiation GO:0045595 320 0.021
muscle system process GO:0003012 115 0.021
cellular response to high density lipoprotein particle stimulus GO:0071403 2 0.021
amine metabolic process GO:0009308 38 0.021
cytokine biosynthetic process GO:0042089 3 0.021
cellular cation homeostasis GO:0030003 180 0.021
oxidation reduction process GO:0055114 304 0.020
dna metabolic process GO:0006259 96 0.020
response to camp GO:0051591 91 0.020
positive regulation of synaptic transmission GO:0050806 62 0.020
response to oxidative stress GO:0006979 186 0.020
lipid metabolic process GO:0006629 283 0.020
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.019
reproductive process GO:0022414 372 0.019
positive regulation of protein transport GO:0051222 41 0.019
response to carbohydrate GO:0009743 183 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
regulation of signal transduction GO:0009966 318 0.019
regulation of defense response GO:0031347 68 0.019
cellular response to oxidative stress GO:0034599 76 0.019
urinary bladder smooth muscle contraction GO:0014832 4 0.019
positive regulation of peptide secretion GO:0002793 52 0.019
receptor metabolic process GO:0043112 18 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
fractalkine metabolic process GO:0050756 3 0.018
regulation of adenylate cyclase activity GO:0045761 18 0.018
regulation of response to tumor cell GO:0002834 3 0.018
regulation of mast cell chemotaxis GO:0060753 1 0.018
anion transmembrane transport GO:0098656 77 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
response to histamine GO:0034776 3 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
catabolic process GO:0009056 351 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
cellular amine metabolic process GO:0044106 38 0.018
nucleic acid templated transcription GO:0097659 379 0.017
action potential GO:0001508 54 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
single organism biosynthetic process GO:0044711 342 0.017
respiratory system process GO:0003016 3 0.017
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.017
cyclic nucleotide metabolic process GO:0009187 80 0.017
positive regulation of neuron projection development GO:0010976 99 0.017
development of primary sexual characteristics GO:0045137 107 0.017
positive regulation of necrotic cell death GO:0010940 4 0.017
positive regulation of mapk cascade GO:0043410 92 0.017
myelination GO:0042552 39 0.017
neuronal action potential GO:0019228 35 0.017
hormone metabolic process GO:0042445 69 0.016
regulation of hormone levels GO:0010817 187 0.016
positive regulation of saliva secretion GO:0046878 3 0.016
axon development GO:0061564 96 0.016
regulation of synaptic transmission GO:0050804 141 0.016
chemosensory behavior GO:0007635 2 0.016
carbohydrate homeostasis GO:0033500 75 0.016
positive regulation of secretion GO:0051047 140 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
aging GO:0007568 241 0.016
chemotaxis GO:0006935 66 0.016
mast cell chemotaxis GO:0002551 4 0.016
regulation of protein metabolic process GO:0051246 289 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
positive regulation of fat cell proliferation GO:0070346 1 0.016
regulation of catalytic activity GO:0050790 304 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.016
cellular component biogenesis GO:0044085 368 0.016
synapse organization GO:0050808 46 0.016
positive regulation of cell development GO:0010720 176 0.016
cellular lipid metabolic process GO:0044255 208 0.016
regulation of tube size GO:0035150 89 0.016
peptide metabolic process GO:0006518 32 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
cytokine metabolic process GO:0042107 6 0.015
immune response to tumor cell GO:0002418 3 0.015
reproductive structure development GO:0048608 128 0.015
negative regulation of long term synaptic potentiation GO:1900272 1 0.015
cyclic nucleotide biosynthetic process GO:0009190 63 0.015
cellular catabolic process GO:0044248 295 0.015
protein oligomerization GO:0051259 191 0.015
regulation of chronic inflammatory response to non antigenic stimulus GO:0002880 1 0.015
epiboly GO:0090504 2 0.015
cell chemotaxis GO:0060326 31 0.015
response to purine containing compound GO:0014074 126 0.015
positive regulation of locomotion GO:0040017 102 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
response to increased oxygen levels GO:0036296 45 0.015
response to fibroblast growth factor GO:0071774 29 0.015
cell migration GO:0016477 197 0.015
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.015
alcohol biosynthetic process GO:0046165 38 0.015
regulation of multicellular organismal development GO:2000026 376 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
negative regulation of cell differentiation GO:0045596 99 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
muscle structure development GO:0061061 87 0.015
positive regulation of chemotaxis GO:0050921 23 0.015
regulation of body fluid levels GO:0050878 90 0.014
response to nutrient GO:0007584 248 0.014
cellular response to molecule of bacterial origin GO:0071219 56 0.014
cyclic purine nucleotide metabolic process GO:0052652 62 0.014
regulation of nucleotide biosynthetic process GO:0030808 47 0.014
multicellular organismal signaling GO:0035637 44 0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.014
positive regulation of lymphocyte migration GO:2000403 1 0.014
negative regulation of innate immune response GO:0045824 4 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
regulation of neurogenesis GO:0050767 247 0.014
platelet derived growth factor production GO:0090360 2 0.014
ion transmembrane transport GO:0034220 365 0.014
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.014
response to oxygen levels GO:0070482 265 0.014
salivary gland development GO:0007431 3 0.014
regulation of camp metabolic process GO:0030814 43 0.014
response to hypoxia GO:0001666 231 0.014
regulation of blood vessel size GO:0050880 89 0.014
positive regulation of developmental process GO:0051094 283 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
positive regulation of the force of heart contraction by chemical signal GO:0003099 2 0.014
gland development GO:0048732 155 0.013
regulation of secretion by cell GO:1903530 208 0.013
response to bacterium GO:0009617 200 0.013
protein maturation GO:0051604 68 0.013
programmed necrotic cell death GO:0097300 2 0.013
chronic inflammatory response to non antigenic stimulus GO:0002545 1 0.013
cell adhesion GO:0007155 110 0.013
cellular response to peptide GO:1901653 133 0.013
purine ribonucleotide biosynthetic process GO:0009152 81 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
cardiovascular system development GO:0072358 134 0.013
cellular response to glucose stimulus GO:0071333 65 0.013
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.013
g protein coupled receptor internalization GO:0002031 3 0.013
positive regulation of mast cell activation GO:0033005 4 0.013
cellular component movement GO:0006928 248 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
regulation of protein localization GO:0032880 81 0.013
organic acid transport GO:0015849 116 0.013
cell projection organization GO:0030030 302 0.013
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
divalent inorganic cation transport GO:0072511 134 0.013
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.013
negative regulation of cell death GO:0060548 229 0.013
macromolecular complex assembly GO:0065003 273 0.013
reproductive system development GO:0061458 128 0.013
response to mechanical stimulus GO:0009612 134 0.013
nucleotide metabolic process GO:0009117 279 0.013
regulation of programmed cell death GO:0043067 341 0.013
organic hydroxy compound transport GO:0015850 77 0.013
necroptotic process GO:0070266 2 0.012
cellular response to mechanical stimulus GO:0071260 48 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
positive regulation of cell death GO:0010942 184 0.012
response to low density lipoprotein particle GO:0055098 4 0.012
cellular glucose homeostasis GO:0001678 66 0.012
renal system process GO:0003014 40 0.012
neuropeptide signaling pathway GO:0007218 29 0.012
organ regeneration GO:0031100 101 0.012
response to interleukin 15 GO:0070672 4 0.012
fat soluble vitamin biosynthetic process GO:0042362 2 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
vasoconstriction GO:0042310 54 0.012
apoptotic process GO:0006915 381 0.012
cellular response to alcohol GO:0097306 87 0.012
regulation of cell migration GO:0030334 128 0.012
protein processing GO:0016485 68 0.012
glucose homeostasis GO:0042593 75 0.012
locomotion GO:0040011 237 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
mesenchymal cell proliferation GO:0010463 4 0.012
telencephalon development GO:0021537 62 0.012
regulation of response to stress GO:0080134 126 0.012
organic acid metabolic process GO:0006082 292 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
positive regulation of hormone secretion GO:0046887 65 0.012
sexual reproduction GO:0019953 148 0.012
regulation of angiotensin metabolic process GO:0060177 3 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
regulation of dna metabolic process GO:0051052 60 0.011
regulation of membrane potential GO:0042391 110 0.011
cellular response to carbohydrate stimulus GO:0071322 72 0.011
sequestering of calcium ion GO:0051208 8 0.011
response to tumor cell GO:0002347 4 0.011
response to glucose GO:0009749 136 0.011
wound healing GO:0042060 122 0.011
immune response GO:0006955 104 0.011
response to nutrient levels GO:0031667 370 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
positive regulation of chemokine production GO:0032722 4 0.011
regulation of cell projection organization GO:0031344 175 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
regulation of fibrinolysis GO:0051917 2 0.011
response to sterol GO:0036314 13 0.011
acid secretion GO:0046717 48 0.011
neuron projection development GO:0031175 273 0.011
oxoacid metabolic process GO:0043436 290 0.011
cellular ketone metabolic process GO:0042180 51 0.011
developmental process involved in reproduction GO:0003006 159 0.011
response to corticosteroid GO:0031960 235 0.011
regulation of chronic inflammatory response GO:0002676 3 0.011
cell growth GO:0016049 104 0.011
regulation of vasoconstriction GO:0019229 44 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
angioblast cell migration GO:0035476 1 0.011
regulation of mesenchymal cell proliferation GO:0010464 4 0.011
autophagic cell death GO:0048102 4 0.011
cellular amide metabolic process GO:0043603 44 0.011
eye morphogenesis GO:0048592 4 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
tumor necrosis factor biosynthetic process GO:0042533 1 0.011
response to monosaccharide GO:0034284 159 0.011
protein complex biogenesis GO:0070271 263 0.011
cytosolic calcium ion transport GO:0060401 39 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
sequestering of metal ion GO:0051238 9 0.010
positive regulation of immune system process GO:0002684 90 0.010
skeletal muscle cell differentiation GO:0035914 2 0.010
regulation of homeostatic process GO:0032844 101 0.010
positive regulation of cell migration GO:0030335 96 0.010
circadian rhythm GO:0007623 88 0.010
positive regulation of endothelial cell migration GO:0010595 4 0.010
regulation of nucleic acid templated transcription GO:1903506 380 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
response to muscle stretch GO:0035994 2 0.010
negative regulation of transport GO:0051051 136 0.010
response to lipopolysaccharide GO:0032496 191 0.010
regulation of cell development GO:0060284 263 0.010
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.010
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.010
small molecule biosynthetic process GO:0044283 124 0.010
cell cell signaling GO:0007267 335 0.010

Fcer1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.116
sensory system disease DOID:0050155 0 0.116
disease of anatomical entity DOID:7 0 0.116
eye and adnexa disease DOID:1492 0 0.116
nervous system disease DOID:863 0 0.116
eye disease DOID:5614 0 0.116
retinal degeneration DOID:8466 0 0.031
urinary system disease DOID:18 0 0.021
disease of metabolism DOID:0014667 0 0.014
retinitis pigmentosa DOID:10584 0 0.013